Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- Published
Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease
Nathanson, D., Zethelius, B., Berne, C., Holst, Jens Juul, Sjöholm, A. & Nyström, T., 2009, In: Diabetologia. 53, 2, p. 277-80 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men
Nathanson, D., Zethelius, B., Berne, C., Lind, L., Andrén, B., Ingelsson, E., Holst, Jens Juul & Nyström, T., Mar 2011, In: Diabetic Medicine. 28, 3, p. 301-305 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
Nauck, M. A., Niedereichholz, U., Ettler, R., Holst, Jens Juul, Ørskov, Cathrine, Ritzel, R. & Schmiegel, W. H., Nov 1997, In: American Journal of Physiology (Consolidated). 273, 5 Pt 1, p. E981-8Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM
Nauck, M. A., Wollschläger, D., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Willms, B., Dec 1996, In: Diabetologia. 39, 12, p. 1546-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients
Nauck, M. A., Weber, I., Bach, I., Richter, S., Ørskov, Cathrine, Holst, Jens Juul & Schmiegel, W., Nov 1998, In: Diabetic Medicine Online. 15, 11, p. 937-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections
Nauck, M. A., Siemsglüss, J., Ørskov, Cathrine & Holst, Jens Juul, Mar 1996, In: Zeitschrift fur Gastroenterologie. 34, 3, p. 159-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?
Nauck, M. A., Vardarli, I., Deacon, Carolyn F., Holst, Jens Juul & Meier, J., 2011, In: Diabetologia. 54, 1, p. 10-18 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects
Nauck, M. A., Holle, H., Kahle, M., Tytko, A., Deacon, Carolyn F., Holst, Jens Juul & Meier, J. J., 2020, In: Peptides. 125, 170176.Research output: Contribution to journal › Review › Research › peer-review
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Preserved incretin activity of glucagon-like peptide 1 (7-36 amide) but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
Nauck, M. A., Heimesaat, M. M., Ørskov, C., Holst, Jens Juul, Ebert, R. & Creutzfeldt, W., 1993, In: Journal of Clinical Investigation. 91, p. 301-307Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of glucagon-like peptide-1 (GLP-1) on counterregulatory hormone responses, cognitive functions and insulin secretion during hyperinsulinaemic, stepped hypoglycaemic clamp experiments in healthy volunteers
Nauck, M. A., Heimesaat, M. M., Behle, K., Holst, Jens Juul, Nauck, M. S., Hüfner, M. & Schmiegel, W. H., 2002, In: J. Clin. Endocrinol. Metab.. 87, p. 1239-1246Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure
Nauck, M. A., Sauerwald, A., Ritzel, R., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetes Care. 21, p. 1925-1931Research output: Contribution to journal › Journal article › Research › peer-review
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Normalization of fasting hyperglycaemia by exogenous-glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
Nauck, M. A., Kleine, N., Ørskov, C., Holst, Jens Juul, Willms, B. & Creutzfeldt, W., 1993, In: Diabetologia. 36, p. 741-744Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of GLP-1 on gastric and pancreatic exocrine secretion and on gastrointestinal motility.
Nauck, M. A., Schepp, W., Holst, Jens Juul & Schmiegel, W. H., 1997, The Insulintropic Gut Hormone Glucagon-Like Peptide-1, Front Diabetes vol. 13. Basel: Karger, p. 194-206Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Normalization of sting glycemia by intravenous GLP-1 (7-36amide) or (7-37) in Type 2 diabetic patients
Nauck, M. A., Weber, I., Bach, I., Richter, S. H., Ørskov, C., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetic Medicine. 15, p. 937-945Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 (GLP-1) as a new therapeutic approach for type-2 diabetes.
Nauck, M. A., Holst, Jens Juul, Willms, B. & Schmiegel, W., 1997, In: Exp. Clin. Endocrinol. Diabetes. 105, p. 187-195Research output: Contribution to journal › Journal article › Research › peer-review
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Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide-1
Nauck, M. A., Walberg, J., Vethacke, A., El-Quaghlidi, A., Senkal, M., Holst, Jens Juul, Gallwitz, J. B., Schmidt, W. E. & Schmiegel, W., 2004, In: Regul. Pept.. 118, p. 89-97Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans
Nauck, M. A., Kemmeries, G., Holst, Jens Juul & Meier, J. J., 2011, In: Diabetes. 60, 5, p. 1561-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1
Nauck, M. A., Walberg, J., Vethacke, A., El-Ouaghlidi, A., Senkal, M., Holst, Jens Juul, Gallwitz, B., Gallwitz, J. B., Schmidt, W. E. & Schmiegel, W., 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 89-97 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and type 2-diabetic patients using exendin [9-39] as a GLP-1 receptor antagonist.
Nauck, M. A., Kind, J., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Broschag, M., He, Y., Kjems, L. & Foley, J., 2016, In: Diabetes. 65, 8, p. 2440-2447 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide: A randomized controlled trial in patients with type 2 diabetes
Nauck, M. A., Kahle, M., Baranov, O., Deacon, Carolyn F. & Holst, Jens Juul, 6 Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 200-207 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.
Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In: Regulatory Peptides. 122, 3, p. 209-17 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
Nauck, M. A., Heimesaat, M. M., Behle, K., Holst, Jens Juul, Nauck, M. S., Ritzel, R., Hüfner, M. & Schmiegel, W. H., Mar 2002, In: The Journal of clinical endocrinology and metabolism. 87, 3, p. 1239-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats
Nelson, D. W., Liu, X. W., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-R1264Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats
Nelson, D. W., Murali, S. G., Liu, X. W., Koopmann, M. C., Holst, Jens Juul & Ney, D. M., 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, p. R1175-R1184Research output: Contribution to journal › Journal article › Research › peer-review
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Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats
Nelson, D. W., Liu, X., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., Nov 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-64Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats
Nelson, D. W., Murali, S. G., Liu, X., Koopmann, M. C., Holst, Jens Juul & Ney, D. M., Apr 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, p. R1175-84Research output: Contribution to journal › Journal article › Research › peer-review
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The glucose-lowering effect of the bile acid sequestrant sevelamer in patients with type 2 diabetes is not mediated by glucagon-like peptide 1
Nerild, H. H., Brønden, Andreas, Haddouchi, A. E., Holst, Jens Juul, Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 217-217 422.Research output: Contribution to journal › Conference abstract in journal › Research
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Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility
Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637Research output: Contribution to journal › Journal article › Research › peer-review
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Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer
Nerild, H. H., Brønden, A., Haddouchi, A. E., Ellegaard, A., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 4, p. 1252-1263Research output: Contribution to journal › Journal article › Research › peer-review
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Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
Nielsen, C. K., Øhrstrøm, C. C., Kielgast, U. L., Hansen, D. L., Hartmann, Bolette, Holst, Jens Juul, Lund, Asger Bach, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes Care. 45, 6, p. 1476–1481Research output: Contribution to journal › Journal article › Research › peer-review
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Dasiglucagon Treatment for Postprandial Hypoglycemia After Gastric Bypass: A Randomized, Double-Blind, Placebo-Controlled Trial
Nielsen, C. K., Øhrstrøm, C. C., Houji, I. J. K., Helsted, M. M., Krogh, L. S. L., Johansen, N. J., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Diabetes Care. 46, 12, p. 2208-2217 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes
Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, A. C., Jansen-Olesen, I., Chiarelli, F., Holst, J. J., Hougaard, P. P., Porksen, S., Holl, R., Beaufort, C. D., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L., Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, C., Jansen-Olesen, I. & 11 others, , 2007, In: European Journal of Endocrinology. 156, 6, p. 663-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes
Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, Cathrine, Jansen-Olesen, I., Chiarelli, F., Holst, Jens Juul, Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B. & Hansen, L., Jun 2007, In: European Journal of Endocrinology. Supplement. 156, 6, p. 663-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial
Nielsen, M. M., Sparre, A. B., Holst, Jens Juul, Fenger-Grøn, M., Pedersen, S. B., Astrup, A. & Richelsen, B., 2012, In: European Journal of Clinical Nutrition. 66, 4, p. 523-529 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predictors of weight loss after bariatric surgery - a cross-disciplinary approach combining physiological, social, and psychological measures
Nielsen, M. S., Christensen, Bodil Just, Schmidt, J. B., Tækker, L., Holm, Lotte, Lunn, Susanne, Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Schnurr, T. M., Hansen, Torben, le Roux, C. W., Lund, Thomas Bøker, Floyd, A. K. & Sjödin, Anders Mikael, 2020, In: International Journal of Obesity. 44, 11, p. 2291-2302 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxyntomodulin and glicentin may predict the effect of bariatric surgery on food preferences and weight loss
Nielsen, M. S., Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, le Roux, C. W. & Sjödin, Anders Mikael, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 4, p. e1064-e1074Research output: Contribution to journal › Journal article › Research › peer-review
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Factors associated with favorable changes in food preferences after bariatric surgery
Nielsen, M. S., Christensen, Bodil Just, Ritz, C., Holm, Lotte, Lunn, Susanne, Tækker, L., Schmidt, J. B., Bredie, Wender, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hilbert, A., le Roux, C. W. & Sjödin, Anders Mikael, 2021, In: Obesity Surgery. 31, 8, p. 3514-3524 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients
Nielsen, R., Wiggers, H., Halbirk, M., Bøtker, H., Holst, Jens Juul, Schmitz, O., Frandsen, E. R., Nielsen, S., Møller, N. & Nørrelund, H., 2012, In: Experimental and Clinical Endocrinology and Diabetes. 120, 5, p. 266-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Appetite stimulation with cannabis-based medicine and methods for assessment of glomerular filtration in older patients with medical illness: A study protocol
Nielsen, R. L., Bornæs, O., Storgaard, I. K., Kallemose, T., Jørgensen, L. M., Jawad, B. N., Altintas, I., Juul-larsen, H. G., Tavenier, J., Durhuus, J. A., Bengaard, A. K. P., Holst, J. J., Kolko, M., Sonne, D. P., Breindahl, T., Damgaard, M., Porrini, E., Hornum, M., Andersen, O., Pedersen, M. M. & 6 others, , 2023, In: Basic & Clinical Pharmacology & Toxicology. 133, 3, p. 237-253 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass
Nielsen, S., Svane, M. S., Kuhre, Rune Ehrenreich, Clausen, T. R., Kristiansen, V. B., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., Feb 2017, In: Physiological Reports. 5, 3, 11 p., e13140.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of tumor necrosis factor-alpha infusion on the incretin effect in healthy volunteers
Nielsen, S. T., Lehrskov-Schmidt, L., Krogh-Madsen, R., Solomon, T., Lehrskov-Schmidt, L., Holst, Jens Juul & Møller, K., 31 Jul 2013, In: Diabetes - Metabolism: Research and Reviews (Online). 29, 8, p. 655-663 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro
Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.
Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .Research output: Contribution to journal › Journal article › Research › peer-review
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Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.
Nielsen, T. B., Yderstraede, K. B., Schrøder, H. D., Holst, Jens Juul, Brusgaard, K. & Beck-Nielsen, H., 2003, In: Cell Transplantation. 12, 1, p. 13-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of GLP-2 treatment and antibiotics on gut structure and function during pig weanling diarrhea
Nielsen, T. T., Sangild, Per Torp, Elnif, J., Sorensen, K., Leser, T., Holst, Jens Juul, Hartmann, B., Jensen, B. B. & Hedemann, M. S., 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 161-163 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
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Onset of small intestinal atrophy is associated with reduced intestinal blod flow in TNP-fed neonatal piglets
Niinikoski, H., Stoll, B., Guam, X., Kansagra, K., Lambert, B., Hartmann, B., Holst, Jens Juul & Burrin, D. G., 2004, In: Journal of Nutrition. 134, p. 1467-1474Research output: Contribution to journal › Journal article › Research › peer-review
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Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets
Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In: Journal of Nutrition. 134, 6, p. 1467-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast
Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Bjorck, I. M., 2008, In: Journal of Nutrition. 138, 4, p. 732-739 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning
Nilsson, A. C., Östman, E. M., Knudsen, K. E. B., Holst, Jens Juul & Björck, I. M. E., 1 Nov 2010, In: Journal of Nutrition. 140, 11, p. 1932-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast
Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Björck, I. M. E., Apr 2008, In: Journal of Nutrition. 138, 4, p. 732-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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