Jens Høiriis Nielsen

Jens Høiriis Nielsen

Emeritus

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    ORCID: 0000-0001-8252-3048

    Introductory remarks on publicationslist

    153 scientific publications including 96 original papers, 3 patent applications and 54 reviews book chapters and conference proceedings. In addition app. abstracts and >250 invited lectures.


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    1. Published

      Supravital dithizone staining in the isolation of human and rat pancreatic islets

      Hansen, W. A., Christie, M. R., Kahn, R., Norgaard, A., Abel, I., Petersen, A. M., Jorgensen, D. W., Baekkeskov, S., Nielsen, Jens Høiriis & Lernmark, A., Feb 1989, In: Diabetes Research: Clinical & Experimental. 10, 2, p. 53-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Beta Cell Workshop 2013 Kyoto

      Heller, R. S., Madsen, O. D. & Nielsen, Jens Høiriis, 11 Jun 2013, In: Islets. 5, 3, p. 107-110 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Workshop on programming beta cell development, impairment and regeneration

      Heller, S. & Nielsen, Jens Høiriis, 2012, In: Islets. 4, 2, p. 119-22 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo

      Horn, S., Kirkegaard, J. S., Hoelper, S., Seymour, Philip Allan, Rescan, C., Nielsen, Jens Høiriis, Madsen, O. D., Jensen, J. N., Kruger, M., Gronborg, M. & Ahnfelt-Rønne, J., 2016, In: Molecular endocrinology (Baltimore, Md.). 30, 1, p. 133-143 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Localization and biosynthesis of polyamines in insulin-producing cells

      Hougaard, D. M., Larsson, L. I. & Nielsen, Jens Høiriis, 15 Aug 1986, In: Biochemical Journal. 238, 1, p. 43-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Effect of Diabetes on Circulating Pancreatic Hormones in Pregnant Rats and Their Offspring

      Iessi, I. L., Sinzato, Y. K., Gallego, F. Q., Nielsen, Jens Høiriis & Damasceno, D. C., Sep 2016, In: Hormone and Metabolic Research. 48, 10, p. 682-686 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      CXCL12/SDF-1 over-expression in human insulinomas and its biological relevance

      Ilhan, A., Nabokikh, A., Maj, M., Vidakovic, M., Nielsen, Jens Høiriis, Prikoszovich, T., Niederle, B., Base, W., Luger, A. & Wagner, L., 2009, In: Molecular and Cellular Endocrinology. 298, 1-2, p. 1-10 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Trefoil factors are expressed in human and rat endocrine pancreas: differential regulation by growth hormone.

      Jackerott, M., Lee, Y. C., Møllgård, Kjeld, Kofod, H., Jensen, J., Rohleder, S., Neubauer, N., Gaarn, L. W., Lykke, J., Dodge, R., Dalgaard, L. T., Søstrup, B., Jensen, D. B., Thim, L., Nexø, E., Thams, P., Bisgaard, Hanne Cathrine & Nielsen, Jens Høiriis, 2006, In: Endocrinology. 147, 12, p. 5752-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      STAT5 activity in pancreatic beta-cells influences the severity of diabetes in animal models of type 1 and 2 diabetes.

      Jackerott, M., Møldrup, A., Thams, P., Galsgaard, E. D., Knudsen, J., Lee, Y. C. & Nielsen, Jens Høiriis, 2006, In: Diabetes. 55, 10, p. 2705-12 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration.

      Jelnes, P., Santoni-Rugiu, E., Rasmussen, M., Friis, S. L., Nielsen, Jens Høiriis, Tygstrup, N. & Bisgaard, Hanne Cathrine, 2007, In: Hepatology. 45, 6, p. 1462-70 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      STAT5 activation by human GH protects insulin-producing cells against interleukin-1beta, interferon-gamma and tumour necrosis factor-alpha-induced apoptosis independent of nitric oxide production.

      Jensen, J., Galsgaard, E. D., Karlsen, A. E., Lee, Y. C. & Nielsen, Jens Høiriis, 2005, In: Journal of Endocrinology. 187, 1, p. 25-36 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Suppressor of cytokine signaling 3 (SOCS-3) protects ß-cells against interleukin-1ß- and interferon-¿- mediated toxicity

      Karlsen, A. E., Rønn, S. G., Lindberg, K., Jonannesen, J., Galsgaard, E. D., Pociot, F., Nielsen, Jens Høiriis, Mandrup-Poulsen, T. R., Nerup, J. & Billestrup, N., 2001, In: Proceedings of the National Academy of Science of the United States of America. Vol.98, p. 12191-12196

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Programming of glucose-insulin homoeostasis: long-term consequences of pre-natal versus early post-natal nutrition insults. Evidence from a sheep model

      Kongsted, A. H., Tygesen, M. P., Husted, S. V., Oliver, M. H., Tolver, Anders, Christensen, V. G., Nielsen, Jens Høiriis & Nielsen, M. O., 2014, In: Acta Physiologica (Print). 210, 1, p. 84-98 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Cytokine signalling in embryonic stem cells.

      Kristensen, D. M., Kalisz, M. & Nielsen, Jens Høiriis, 2006, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 113, 11-12, p. 756-72 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Tissue-type plasminogen activator in somatostatin cells of rat pancreas and hypothalamus

      Kristensen, P., Larsson, L. I., Danø, K. & Nielsen, Jens Høiriis, Dec 1987, In: Endocrinology. 121, 6, p. 2238-44 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Expression and Localization of microRNAs in Perinatal Rat Pancreas: Role of miR-21 in Regulation of Cholesterol Metabolism

      Larsen, L., Rosenstierne, M. W., Gaarn, L. W., Bagge, A., Pedersen, L., Dahmcke, C. M., Nielsen, Jens Høiriis & Dalgaard, L. T., 11 Oct 2011, In: PLOS ONE. 6, 10, p. e25997 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Localization of microRNA-375 in perinatal rat pancreas

      Larsen, L., Rosenstierne, M. W., Nielsen, Jens Høiriis & Dalgaard, L. T., 2018, In: Non-Coding RNAs in Endocrinology. 3, p. 1-4

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Pancreatic hormones are expressed on the surfaces of human and rat islet cells through exocytotic sites

      Larsson, L. I., Hutton, J. C., Madsen, O. D. & Nielsen, Jens Høiriis, Feb 1989, In: European Journal of Cell Biology. 48, 1, p. 45-51 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Developmental expression of proprotein convertase 1/3 in the rat

      Lee, Y. C., Damholt, A. B., Billestrup, Nils, Kisbye, T., Galante, P., Michelsen, B., Kofod, H. & Nielsen, Jens Høiriis, 10 Sep 1999, In: Molecular and Cellular Endocrinology. 155, 1-2, p. 27-35 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Regulation of beta cell replication.

      Lee, Y. C. & Nielsen, Jens Høiriis, 2008, In: Molecular and Cellular Endocrinology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Reversed-phase high-performance liquid chromatographic analyses of insulin biosynthesis in isolated rat and mouse islets

      Linde, S., Hansen, B. A., Welinder, B. S. & Nielsen, Jens Høiriis, 13 Jan 1989, In: Journal of Chromatography A. 462, p. 243-54 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      High-performance liquid chromatography of rat and mouse islet polypeptides: potential risk of oxidation of methionine residues during sample preparation

      Linde, S., Hansen, Birger, Welinder, B. S. & Nielsen, Jens Høiriis, 24 Aug 1990, In: Journal of Chromatography A. 530, 1, p. 29-37 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Growth hormone is a growth factor for the differentiated pancreatic beta-cell

      Linde, S., Welinder, B. S., Billestrup, Nils, Madsen, O. D. & Nielsen, Jens Høiriis, Jan 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 1, p. 165-73 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Analysis of proinsulin and its conversion products by reversed-phase high-performance liquid chromatography

      Linde, S., Welinder, B. S. & Nielsen, Jens Høiriis, 5 May 1993, In: Journal of Chromatography A. 614, 2, p. 185-204 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function

      Lobie, P. E., Allevato, G., Norstedt, G., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21745-50 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Islet amyloid polypeptide and insulin expression are controlled differently in primary and transformed islet cells

      Madsen, O. D., Michelsen, B. T., Westermark, P., Betsholtz, C., Nishi, M., Steiner, D. F. & Nielsen, Jens Høiriis, Jan 1991, In: Molecular endocrinology (Baltimore, Md.). 5, 1, p. 143-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Mechanisms of pancreatic islet cell destruction. Dose-dependent cytotoxic effect of soluble blood mononuclear cell mediators on isolated islets of Langerhans

      Mandrup-Poulsen, Thomas, Bendtzen, K., Nerup, J., Egeberg, J. & Nielsen, Jens Høiriis, May 1986, In: Allergy. 41, 4, p. 250-9 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity

      Mandrup-Poulsen, Thomas, Egeberg, J., Nerup, J., Bendtzen, K., Dinarello, C. A. & Nielsen, Jens Høiriis, Apr 1987, In: Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology. 95, 2, p. 55-63 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Direct effects of cyclosporin A on human pancreatic beta-cells

      Mandrup-Poulsen, Thomas, Nerup, J. & Nielsen, Jens Høiriis, Sep 1986, In: Diabetes. 35, 9, p. 1049-52 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

      Mandrup-Poulsen, Thomas, Spinas, G. A., Prowse, S. J., Hansen, B. S., Jørgensen, D. W., Bendtzen, K., Nerup, J. & Nielsen, Jens Høiriis, May 1987, In: Diabetes. 36, 5, p. 641-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Cytokines cause functional and structural damage to isolated islets of Langerhans

      Mandrup-Poulsen, Thomas, Bendtzen, K., Bendixen, G., Nerup, J. & Nielsen, Jens Høiriis, Aug 1985, In: Allergy. 40, 6, p. 424-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans

      Mandrup-Poulsen, Thomas, Bendtzen, K., Nerup, J., Dinarello, C. A., Svenson, M. & Nielsen, Jens Høiriis, Jan 1986, In: Diabetologia. 29, 1, p. 63-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Functional characteristics of neonatal rat β cells with distinct markers

      Martens, G. A., Motté, E., Kramer, G., Stangé, G., Gaarn, L. W., Hellemans, K., Nielsen, Jens Høiriis, Aerts, J. M., Ling, Z. & Pipeleers, D., Feb 2014, In: Journal of Molecular Endocrinology. 52, 1, p. 11-28 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Gene probes to detect cross-culture contamination in hormone producing cell lines

      Matsuba, I., Lernmark, A., Madsen, O. D., Michelsen, B., Nielsen, Jens Høiriis, Scholler, J., Vissing, Henrik, Welinder, B., Tommerup, Niels & Mikkelsen, M., Nov 1988, In: In Vitro Cellular & Developmental Biology. 24, 11, p. 1071-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Regulation of integrin alpha 6A by lactogenic hormones in rat pancreatic beta-cells: Implications for the physiological adaptation to pregnancy

      Moldrup, A., Lindberg, M. N., Galsgaard, E. D., Henriksen, U., Dalgaard, L. T. & Nielsen, Jens Høiriis, 2020, In: Acta Physiologica. 229, 3, 13 p., 13454.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Multiple growth hormone-binding proteins are expressed on insulin-producing cells

      Møldrup, A., Billestrup, Nils, Thorn, N. A., Lernmark, A. & Nielsen, Jens Høiriis, Aug 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 8, p. 1173-82 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Effects of sex and pregnancy hormones on growth hormone and prolactin receptor gene expression in insulin-producing cells

      Møldrup, A., Petersen, E. D. & Nielsen, Jens Høiriis, Sep 1993, In: Endocrinology. 133, 3, p. 1165-72 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Growth hormone action in rat insulinoma cells expressing truncated growth hormone receptors

      Møldrup, A., Allevato, G., Dyrberg, T., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1991, In: The Journal of Biological Chemistry. 266, 26, p. 17441-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Expression of the growth hormone receptor gene in insulin producing cells

      Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1151-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Rat insulinoma cells express both a 115-kDa growth hormone receptor and a 95-kDa prolactin receptor structurally related to the hepatic receptors

      Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 25 May 1990, In: The Journal of Biological Chemistry. 265, 15, p. 8686-90 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Reduced TGF-beta1 expression and its target genes in human insulinomas

      Nabokikh, A., Ilhan, A., Bilban, M., Gartner, W., Vila, G., Niederle, B., Nielsen, Jens Høiriis, Wagner, O., Base, W., Luger, A. & Wagner, L., 2007, In: Experimental and Clinical Endocrinology and Diabetes. 115, 10, p. 674-682 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Implications for the offspring of circulating factors involved in beta cell adaptation in pregnancy

      Nalla, A., Ringholm, L., Søstrup, B., Højrup, P., Thim, L., Levery, S. B., Vakhrushev, Sergey, Billestrup, Nils, Mathiesen, Elisabeth, Damm, Peter & Nielsen, Jens Høiriis, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1181-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Possible mechanisms involved in improved beta cell function in pregnant women with type 1 diabetes

      Nalla, A., Ringholm, L., Sorensen, S. N., Damm, Peter, Mathiesen, Elisabeth & Nielsen, Jens Høiriis, 2020, In: Heliyon. 6, 8, 6 p., 04569.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Impact of fetal and neonatal environment on beta cell function and development of diabetes

      Nielsen, Jens Høiriis, Haase, T. N., Jaksch, C., Nalla, A., Søstrup, B., Nalla, A. A., Larsen, L., Rasmussen, M., Dalgaard, L. T., Gaarn, L. W., Thams, P., Kofod, H. & Billestrup, Nils, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1109-22 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      β-Cell Adaptability during Pregnancy

      Nielsen, Jens Høiriis, Horn, S., Kirkegaard, J. S., Nalla, A. & Søstrup, B., 2016, Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes. Bentham Science Publishers, p. 123-168 45 p. (Current and Future Developments in Physiology, Vol. 1).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    46. Published

      Mechanisms of pancreatic beta-cell growth and regeneration: studies on rat insulinoma cells

      Nielsen, Jens Høiriis, 1989, In: Experimental and Clinical Endocrinology and Diabetes. Supplement. 93, 2-3, p. 277-85 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      AKAP 18 a and g have opposing effects on insulin release in INS 1E cells

      Nielsen, Jens Høiriis, Lee, Y. C. & Thams, P. G., 2010, In: FEBS Letter. 584, p. 81-85

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Growth and function of the pancreatic beta cell in vitro: effects of glucose, hormones and serum factors on mouse, rat and human pancreatic islets in organ culture

      Nielsen, Jens Høiriis, 1985, In: Acta endocrinologica. Supplementum. 266, p. 1-39 39 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Beta cell proliferation and growth factors

      Nielsen, Jens Høiriis, Svensson, C., Møldrup, A., Galsgaard, E. D. & Billestrup, Nils, Jan 1999, In: Journal of Molecular Medicine. 77, 1, p. 62-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Dissociation between insulin secretion and DNA synthesis in cultured pancreatic islets

      Nielsen, Jens Høiriis, 1985, In: Biomedica Biochimica Acta. 44, 1, p. 161-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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