Thomas Jespersen

Thomas Jespersen

Professor

Member of:


    1. 2015
    2. Published

      Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

      Axelsen, L. N., Callø, Kirstine, Braunstein, T. H., Riemann, Mads, Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, Kristine Boisen, Bartels, Emil Daniel, Baandrup, U., Jespersen, Thomas, Nielsen, L. B., von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Antiarrhythmic effect of either negative modulation or blockade of small conductance Ca2+ activated K+ channels on ventricular fibrillation in guinea pig Langendorff perfused heart

      Diness, J. G., Kirchhoff, J. E., Sheykhzade, Majid, Jespersen, Thomas & Grunnet, M., 8 May 2015, In: Journal of Cardiovascular Pharmacology. 66, 3, p. 294–299 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses

      Haugaard, M. M., Pehrson, S., Carstensen, Helena, Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, Thomas & Buhl, Rikke, 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses

      Haugaard, M. M., Hesselkilde, E. Z., Pehrson, S. M., Carstensen, Helena, Madsen, M. F., Præstegaard, K. F., Sørensen, U. S., Diness, J. G., Grunnet, M., Buhl, Rikke & Jespersen, Thomas, Apr 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 4, p. 825-835 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Common and rare variants in SCN10A modulate the risk of atrial fibrillation.

      Jabbari, J., Olesen, Morten Steen Salling, Yuan, L., Nielsen, J. B., Liang, B., Macri, V., Christophersen, I. E., Nielsen, N., Sajadieh, Ahmad, Ellinor, P. T., Grunnet, Morten, Haunsø, Stig, Holst, A. G., Svendsen, Jesper Hastrup & Jespersen, Thomas, 2015, In: Circulation: Cardiovascular Genetics. 8, 1, p. 64-73 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family

      Kanters, Jørgen K., Skibsbye, L., Hedley, P. L., Dembic, M., Liang, B., Hagen, C. M., Eschen, O., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 2015, In: Scandinavian Journal of Clinical & Laboratory Investigation. 75, 8, p. 699-709 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Synergistic antiarrhythmic effect of combining inhibition of Ca(2+)-activated K(+) (SK) channels and voltage-gated Na(+) channels in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Goldin Diness, J., Sheykhzade, Majid, Grunnet, M. & Jespersen, Thomas, Feb 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 2, p. 409-18 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

      Poulet, C., Wettwer, E., Grunnet, Morten, Jespersen, Thomas, Fabritz, L., Matschke, K., Knaut, M. & Ravens, U., 29 Jun 2015, In: PLOS ONE. 10, 6, p. 1-19 19 p., e0131432.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

      Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

      Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Biophysical characterization of KV3.1 potassium channel activating compounds

      Taskin, B., von Schoubye, N. L., Sheykhzade, Majid, Bastlund, J. F., Grunnet, M. & Jespersen, Thomas, 5 Jul 2015, In: European Journal of Pharmacology. 758, p. 164-170 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

      Winkel, B. G., Yuan, L., Olesen, Morten Steen Salling, Sadjadieh, G., Wang, Y., Risgaard, B., Jabbari, R., Haunsø, Stig, Holst, A. G., Hollegaard, M. V., Tfelt-Hansen, J. & Jespersen, Thomas, Jun 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 6, p. 1241-1249 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. 2016
    15. Published

      The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish

      Berchtold, Martin Werner, Zacharias, T., Kulej, K., Wang, K., Torggler, R., Jespersen, Thomas, Chen, J. N., Larsen, M. R. & la Cour, J. M., 2016, In: Journal of Biological Chemistry. 291, 52, p. 26636-26646 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Diness, Jonas Goldin, Abildgaard, L., Sheykhzade, Majid, Grunnet, Morten & Jespersen, Thomas, 8 Oct 2016, In: Pfluegers Archiv. 468, 11, p. 1853–1863 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

      Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Refractoriness in human atria: Time and voltage dependence of sodium channel availability

      Skibsbye, L., Jespersen, Thomas, Christ, T., Maleckar, M. M., van den Brink, J., Tavi, P. & Koivumäki, J. T., Dec 2016, In: Journal of Molecular and Cellular Cardiology. 101, p. 26-34 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation

      van der Heyden, M. A. G. & Jespersen, Thomas, 15 Jan 2016, In: European Journal of Pharmacology. 771, p. 56-64 9 p.

      Research output: Contribution to journalReviewResearchpeer-review

    20. 2017
    21. Published

      Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons

      Boddum, K., Hougaard, C., Xiao-Ying Lin, J., von Schoubye, N. L., Jensen, H. S., Grunnet, M. & Jespersen, Thomas, 2017, In: Neuropharmacology. 118, p. 102-112 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

      Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations

      Glinge, C., Clauss, S., Boddum, K., Jabbari, R., Jabbari, J., Risgaard, B., Tomsits, P., Hildebrand, B., Kääb, S., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2017, In: PLOS ONE. 12, 2, 16 p., e0167969.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation

      Hesselkilde, E. Z., Carstensen, Helena, Haugaard, M. M., Carlson, J., Pehrson, S., Jespersen, Thomas, Buhl, Rikke & Platonov, P. G., Dec 2017, In: B M C Cardiovascular Disorders. 17, 6 p., 289.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts

      Hoeker, G. S., Skarsfeldt, M. A., Jespersen, Thomas & Poelzing, S., Jan 2017, In: Physiological Reports. 5, 1, 10 p., e13120.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Pharmacological blockade of small conductance Ca-activated K channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

      Hundahl, L. A., Sattler, S. M., Skibsbye, L., Diness, J. G., Tfelt-Hansen, Jacob & Jespersen, Thomas, Jun 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 5-6, p. 739-750 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Rat Models of Ventricular Fibrillation Following Acute Myocardial Infarction

      Hundahl, L. A., Tfelt-Hansen, Jacob & Jespersen, Thomas, Nov 2017, In: Journal of Cardiovascular Pharmacology and Therapeutics. 22, 6, p. 514-528 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

    ID: 8117