Jens Juul Holst

Jens Juul Holst

Professor


  1. 1994
  2. Published

    Peptide-evoked release of amylase from isolated acini of the rat parotid gland

    Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, Steen Seier & Holst, Jens Juul, 26 May 1994, In: Regulatory Peptides. 51, 3, p. 237-54 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Peptidergic control of amylase secretion from the rat parotid gland

    Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, S. S. & Holst, Jens Juul, 1994, In: Regulatory Peptides. 51, p. 237-254

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Subcutaneous injection of glucagon-like insulintropic peptide reduces postprandial glycemia in non-insulin dependent diabetes

    Gutniak, M. K., Linde, B., Holst, Jens Juul & Efendic, S., 1994, In: Diabetes Care. 17, p. 1039-1044

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Glucagon-like peptide 1: on its way to clinical application

    Göke, B., Göke, R., Holst, Jens Juul & Ørskov, C., 1994, In: Digestion. 54, p. 339-340

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Proglucagon processing in porcine and human pancreas

    Holst, Jens Juul, Bersani, M., Johnsen, A. H., Kofod, H., Hartmann, Bolette & Ørskov, Cathrine, 1994, In: Journal of Biological Chemistry. 269, 29, p. 18827-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Glucagon and other proglucagon-derived peptides

    Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  8. Published

    Glucagon-like peptide-1 (GLP-1) - A newly discovered Gl Hormone. Review.

    Holst, Jens Juul, 1994, In: Today in Medicine. Gastroenterology. 107, p. 1848-1855

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Gut hormones and intestinal function

    Holst, Jens Juul & Schmidt, P., 1994, The Gut as an Endocrine Organ. Clinics in Endocrinology and Metabolism, Vol 8. Bailliere, p. 137-164

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  10. Published

    Isolated organs as replacements for vertebrate animals

    Holst, Jens Juul, 1994, Handbook of Laboratory Animal Science. USA: CRC Press, p. 397-408

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  11. Published

    Nitric oxide (NO) is an important element in neurally induced pancreatic exocrine secretion in pigs

    Holst, Jens Juul, Rasmussen, T. N. & Schmidt, P., 1994, In: Am J Physiology. 29, p. G206-G213

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, Jan 1994, In: Metabolism. 43, 1, p. 104-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Effect of glucagon-like peptide-1 (proglucagon 78 - 107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Holst, Jens Juul & Ørskov, C., 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans

    Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, Apr 1994, In: Diabetes. 43, 4, p. 535-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Physiol.. 267, p. E549-E559

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Postprandial lipid oxidation reduced and carbohydrate oxidation increased in postobese subjects

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, Obesity in Europe. John Libbey, p. 135-137

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  18. Published

    Resistant starch: The effect on postprandial glycemia, hormonal response and satiety

    Raben, A., Tagliabue, A., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 60, p. 544-551

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Decreased postprandial thermogenesis and fat oxidation, but increased fullness after a high-fiber meal compared to a low-fiber meal

    Raben, A. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 59, p. 1386-1394

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, Anne, Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, In: American Journal of Physiology: Endocrinology and Metabolism. 267, 4 part 1, p. E549-E559 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Pigs produce only a single form of CGRP, part of which is processed to N- and C-terminal fragments

    Rasmussen, T. N., Bersani, M., Johnsen, A. H., Kofod, H. & Holst, Jens Juul, 1994, In: Peptides. 15, 1, p. 89-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Exendin-4 and exendin (9-39)NH*U2-agonist and antagonist, respectively, at the rat parietal cell receptor for glucagon-like peptide-1 (7-36)NH*U2

    Schepp, W., Schmidtler, J. & Holst, Jens Juul, 1994, In: Eur. J. Pharmacol.. 269, p. 183-191

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Cholecystokinin is a negative regulator of gastric acid secretion and postprandial release of gastrin in humans.

    Schmidt, W. E., Schenk, S., Nustede, R., Rovati, L. C., Holst, Jens Juul, Fölsch, U. & Creutzfeldt, W., 1994, In: Today in Medicine. Gastroenterology. 107, p. 1610-1620

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Rat parietal cell receptors for GLP-1 (7-36) amide: Northern blot, cross-linking, and radioligand binding

    Schmidtler, J., Dehne, K., Allescher, H. D., Schusdziarra, V., Classen, M., Holst, Jens Juul, Polack, A. & Schepp, W., 1994, In: Am. J. Physiol.. 267, p. G423-G432

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland

    Thulesen, J., Rasmussen, T. N., Schmidt, P., Holst, Jens Juul & Poulsen, Steen Seier, Dec 1994, In: Histochemistry. 102, 6, p. 437-444 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. P. & Holst, Jens Juul, Jun 1994, In: Scandinavian Journal of Gastroenterology. 29, 6, p. 501-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Glucagon-like peptide-1 (GLP-1) 7-36 amide and peptide YY from L-cell in the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. & Holst, Jens Juul, 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 501-505

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Production and secretion of amidated and glycine-extended glucagon-like peptide-1 (GLP) in man

    Ørskov, C., Rabenhøj, L., Kofod, H., Wettergren, A. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-39

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans

    Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-539

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 1995
  31. Published

    Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis.

    Blume, N., Skouv, J., Larsson, L., Holst, Jens Juul & Madsen, O. D., 1995, In: J. Clin. Invest.. 96, p. 2227-2235

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The role of glucagon in the maintenance of euglycemia in the fed and the fasted state. Monoclonal antibody treatment as a tool in glucagon physiology in rats.

    Brand, C. L., Jørgensen, P. N., Svendsen, I., Kristensen, J. S., Knigge, U., Warberg, J. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. E469-E477

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Effect of endogenous hypergastrinemia on gastrin receptor expressing human colon carcinoma transplanted to athymic rats.

    Chu, M., Franzén, L., Rehfeld, J. F., Holst, Jens Juul & Borch, K., 1995, In: Today in Medicine. Gastroenterology. 109, p. 1415-1420

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

    Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Sympathoadrenal regulation of adrenocortical steroidogenesis

    Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8

    Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus.

    Hannibal, J., Mikkelsen, J. D., Clausen, H., Holst, Jens Juul, Wulff, B. S. & Fahrenkrug, J., 1995, In: Regulatory Peptides. 55, p. 133-148

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.

    Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Human Glucagon-like peptide-1, - six important topics.

    Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System.. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 537-546

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  42. Published

    Ileal release of glucagonlike peptide-1 (GLP-1): association with inhibition of gastric acid in humans

    Layer, P., Holst, Jens Juul, Grandt, D. & Goebell, H., 1995, In: Digestive Disease Science. 40, p. 1074-82

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Postprandial glucagon-like peptide-1 (GLP-1) release in states of normal and disturbed luminal nutrient digestion.

    Layer, P., v d Ohe, M. & Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 547-550

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  44. Published

    Transplantable glucagonomas derived from pluripotent rat islet tumor tissue cause severe anorexia and adipsia

    Madsen, O. D., Karlsen, C., Blume, N., Jensen, H. I., Larsson, L. & Holst, Jens Juul, 1995, In: Scand. J. Clin. Lab. Invest.. 55, suppl. 220, p. 27-36

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Histochemical, pharmacological, biochemical and chromatographic evidence that pituitary adenylyl cyclase activating peptide is involved in inhibitory neurotransm.in the taenia of the guinea-pig caecum

    McConalogue, K., Furness, J. B., Vremec, M. A., Holst, Jens Juul, Tornøe, K. & Marley, P. D., 1995, In: J. Autonom Nerv. System. 50, p. 311-322

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Presence of somatostatin containing neuronal-like cells in the rat pineal gland.

    Møller, M., Holst, Jens Juul, Mikkelsen, J. D. & Webb, S., 1995, In: Neuroendocrinol. Letters. 17, p. 71-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Comparison of sandwich ELISA and RIA for determination of exogenous GLP-1 (7-36 amide) in plasma.

    Pridal, L., Ingwersen, S. H., Larsen, F. S., Holst, Jens Juul, Adelhorst, K. & Kirk, O., 1995, In: J Pharmaceutical and Biomedical Analysis. 13, p. 841-850

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glucagon-like peptide 1 (GLP-1)(7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using alpha-glucosidase inhibition (acarbose).

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, C. & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Insulintropic actions of intravenous glucagon-like peptide-1 (GLP-1) (7-36 amide) in the fasting state in healthy subjects

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Acta Diabetologica. 32, p. 13-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Increases in plasma motilin follow each episode of gallbladder emptying during the interdigestive period and changes in serum bile acid concentration correlate to plasma motilin.

    Qvist, N., Øster-Jørgensen, E., Pedersen, S. A., Rasmussen, L., Hovendal, C. & Holst, Jens Juul, 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 122-127

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Pharmacokinetic, insulinotropic and glucagonostatic properties of GLP-1 (7-36 amide) after subcutaneous injection in healthy volunteers. Dose-response-relationships

    Ritzel, R., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., 1995, In: Diabetologia. 38, p. 720-725

    Research output: Contribution to journalJournal articleResearchpeer-review

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