Neurotensin-like immunoreactivity after intestinal resection in the rat

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Neurotensin-like immunoreactivity after intestinal resection in the rat. / Poulsen, Steen Seier.

In: Gut, Vol. 28, No. 9, 09.1987, p. 1107-11.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Poulsen, SS 1987, 'Neurotensin-like immunoreactivity after intestinal resection in the rat', Gut, vol. 28, no. 9, pp. 1107-11.

APA

Poulsen, S. S. (1987). Neurotensin-like immunoreactivity after intestinal resection in the rat. Gut, 28(9), 1107-11.

Vancouver

Poulsen SS. Neurotensin-like immunoreactivity after intestinal resection in the rat. Gut. 1987 Sep;28(9):1107-11.

Author

Poulsen, Steen Seier. / Neurotensin-like immunoreactivity after intestinal resection in the rat. In: Gut. 1987 ; Vol. 28, No. 9. pp. 1107-11.

Bibtex

@article{6ac09215dac34eea9bf0087a0fa6fdf5,
title = "Neurotensin-like immunoreactivity after intestinal resection in the rat",
abstract = "Neurotensin is a tridecapeptide located mainly in the distal small intestine. The present study was carried out in order to investigate the neurotensin response after proximal small intestinal resection in the rat. After resection, the median plasma concentration of neurotensin like immunoreactivity (NTLI) was unchanged compared with sham operated rats. Intragastric instillation of fat increased the plasma concentration of NTLI from 45 pmol/l (34-63) in sham operated rats to 92 pmol/l (46-121) in resected rats. No significant increase in the plasma concentration of NTLI was found after intragastric instillation of amino acids or glucose. The tissue concentration of NTLI increased significantly in the jejunum and ileum after proximal small intestinal resection, while the number of immunoreactive neurotensin cells was unchanged. This study shows that the adaptive responses in the distal small intestine after proximal small intestinal resection also involve the neurotensin producing cells.",
keywords = "Animals, Chromatography, Gel, Hypertrophy, Ileum, Intestinal Mucosa, Intestine, Small, Jejunum, Male, Neuropeptides, Neurotensin, Rats, Rats, Inbred Strains",
author = "Poulsen, {Steen Seier}",
year = "1987",
month = sep,
language = "English",
volume = "28",
pages = "1107--11",
journal = "Gut",
issn = "0017-5749",
publisher = "B M J Group",
number = "9",

}

RIS

TY - JOUR

T1 - Neurotensin-like immunoreactivity after intestinal resection in the rat

AU - Poulsen, Steen Seier

PY - 1987/9

Y1 - 1987/9

N2 - Neurotensin is a tridecapeptide located mainly in the distal small intestine. The present study was carried out in order to investigate the neurotensin response after proximal small intestinal resection in the rat. After resection, the median plasma concentration of neurotensin like immunoreactivity (NTLI) was unchanged compared with sham operated rats. Intragastric instillation of fat increased the plasma concentration of NTLI from 45 pmol/l (34-63) in sham operated rats to 92 pmol/l (46-121) in resected rats. No significant increase in the plasma concentration of NTLI was found after intragastric instillation of amino acids or glucose. The tissue concentration of NTLI increased significantly in the jejunum and ileum after proximal small intestinal resection, while the number of immunoreactive neurotensin cells was unchanged. This study shows that the adaptive responses in the distal small intestine after proximal small intestinal resection also involve the neurotensin producing cells.

AB - Neurotensin is a tridecapeptide located mainly in the distal small intestine. The present study was carried out in order to investigate the neurotensin response after proximal small intestinal resection in the rat. After resection, the median plasma concentration of neurotensin like immunoreactivity (NTLI) was unchanged compared with sham operated rats. Intragastric instillation of fat increased the plasma concentration of NTLI from 45 pmol/l (34-63) in sham operated rats to 92 pmol/l (46-121) in resected rats. No significant increase in the plasma concentration of NTLI was found after intragastric instillation of amino acids or glucose. The tissue concentration of NTLI increased significantly in the jejunum and ileum after proximal small intestinal resection, while the number of immunoreactive neurotensin cells was unchanged. This study shows that the adaptive responses in the distal small intestine after proximal small intestinal resection also involve the neurotensin producing cells.

KW - Animals

KW - Chromatography, Gel

KW - Hypertrophy

KW - Ileum

KW - Intestinal Mucosa

KW - Intestine, Small

KW - Jejunum

KW - Male

KW - Neuropeptides

KW - Neurotensin

KW - Rats

KW - Rats, Inbred Strains

M3 - Journal article

C2 - 3678970

VL - 28

SP - 1107

EP - 1111

JO - Gut

JF - Gut

SN - 0017-5749

IS - 9

ER -

ID: 47488614