Lærke Smidt Gasbjerg
Postdoc, Assistant Professor
Molecular and Translational Pharmacology
Blegdamsvej 3, 2200 København N.
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- Published
GIP's effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3-30)NH2
Gasbjerg, Lærke Smidt, Hartmann, Bolette, Christensen, Mikkel Bring, Lanng, A. R., Vilsbøll, Tina, Jørgensen, Niklas Rye, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 130, 6 p., 115079 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects
Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment
Gabe, M. B. N., Skov-Jeppesen, Kirsa, Gasbjerg, Lærke Smidt, Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., Oeke, J., Pedersen, Lola Julie Torz, Veedfald, Simon, Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: Pharmacological Research. 176, 106058.Research output: Contribution to journal › Journal article › Research › peer-review
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Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice
Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689Research output: Contribution to journal › Journal article › Research › peer-review
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Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors
Gabe, M. B. N., Sparre-Ulrich, A. H., Pedersen, M. F., Gasbjerg, Lærke Smidt, Inoue, A., Bräuner, Hans, Hartmann, Bolette & Rosenkilde, M. M., 31 Jan 2018, In: Biochemical Pharmacology. 150, p. 97-107 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular interactions of full-length and truncated GIP peptides with the GIP receptor - A comprehensive review
Gabe, M. B. N., van der Velden, W. J. C., Smit, F. X., Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2020, In: Peptides. 125, 8 p., 170224.Research output: Contribution to journal › Review › Research › peer-review
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N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction
Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485Research output: Contribution to journal › Journal article › Research › peer-review
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The Combination of Fosfomycin, Metronidazole, and Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor is Stable in vitro and Has Maintained Antibacterial Activity
Fonnes, S., Holzknecht, Barbara Juliane, Gasbjerg, Lærke Smidt, Weisser, J. J., Hallberg, H. W., Arpi, M. & Rosenberg, Jacob, 2018, In: Drug Research. 68, 6, p. 349-354Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal expression profiles and hepatic expression of LEAP2, ghrelin and their common receptor, GHSR, in humans
Englund, A., Gilliam-Vigh, H., Suppli, M. P., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Peptides. 177, 7 p., 171227.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Intracoronary and Intravenous Melatonin on Myocardial Salvage Index in Patients with ST-Elevation Myocardial Infarction: a Randomized Placebo Controlled Trial
Ekeloef, S., Halladin, N., Fonnes, S., Jensen, S. E., Zaremba, T., Rosenberg, Jacob, Jonsson, G., Aarøe, J., Gasbjerg, Lærke Smidt, Rosenkilde, Mette & Gögenur, Ismail, Dec 2017, In: Journal of Cardiovascular Translational Research. 10, 5-6, p. 470-479 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37775779
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › Research › peer-review
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299
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GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
139
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Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats
Research output: Contribution to journal › Journal article › Research › peer-review
Published