Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

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    1. Published

      Limited benefit of haemoglobin glycation index as risk factor for cardiovascular disease in type 2 diabetes patients

      Østergaard, H. B., Mandrup-Poulsen, Thomas, Berkelmans, G. F. N., van der Graaf, Y., Visseren, F. L. J. & Westerink, J., 2019, In: Diabetes and Metabolism. 45, 3, p. 254-260 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.

      Zaitseva, I. I., Sharoyko, V., Størling, J., Efendic, S., Guerin, C., Mandrup-Poulsen, Thomas, Nicotera, P., Berggren, P. & Zaitsev, S. V., 2006, In: Biochemical and Biophysical Research Communications. 347, 4, p. 1121-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase

      Zaitseva, I. I., Storling, J., Mandrup-Poulsen, Thomas, Berggren, P. O. & Zaitsev, S. V., 2008, In: Cellular and Molecular Life Sciences. 65, 7-8, p. 1248-1255 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection

      Wagner, F. F., Lundh, M., Kaya, T., McCarren, P., Zhang, Y-L., Chattopadhyay, S., Gale, J. P., Galbo, T., Fisher, S. L., Meier, B. C., Vetere, A., Richardson, S., Morgan, N. G., Christensen, D. P., Gilbert, T. J., Hooker, J. M., Leroy, M., Walpita, D., Mandrup-Poulsen, T., Wagner, B. K. & 1 others, Holson, E. B., 19 Feb 2016, In: ACS chemical biology. 11, 2, p. 363-374 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Protection against inflammatory β-cell damage by lysine deacetylase inhibition and microRNA expression?

      Vestergaard, A. L., Pallesen, E. M. H., Novotny, G. W., Noesgaard, D., Lundh, M., Regazzi, R. & Mandrup-Poulsen, Thomas, 15 Sep 2015. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    6. Published

      A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells

      Vestergaard, A. L., Blankestijn, M., Stahl, J. L., Pallesen, E. M. H., Bang-Berthelsen, C. H., Pociot, Flemming, Novotny, G. W., Lundh, M. & Mandrup-Poulsen, Thomas, 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 8 p., 896.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    7. Published

      MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage

      Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Interaction Between Dietary Iron Intake and Genetically Determined Iron Overload: Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in the TEDDY Study

      Ullitz Thorsen, S., Liu, X., Kataria, Y., Mandrup-poulsen, T., Kaur, S., Uusitalo, U., Virtanen, S. M., Norris, J., Rewers, M., Hagopian, W., Yang, J., She, J., Akolkar, B., Rich, S. S., Aronsson, C. A., Lernmark, Å., Ziegler, A., Toppari, J., Krischer, J. P., Parikh, H. M. & 31 others, Ellervik, Christina, Svensson, Jannet, Rewers, M., Barbour, A., Bautista, K., Baxter, J., Felipe-morales, D., Frohnert, B. I., Stahl, M., Gesualdo, P., Hoffman, M., Karban, R., Liu, E., Munoz, A., Norris, J., O’donnell, H., Peacock, S., Shorrosh, H., Steck, A., Stern, M., Waugh, K., Toppari, J., Simell, O. G., Adamsson, A., Ahonen, S., Åkerlund, M., Anttila, S., Hakola, L., Hekkala, A., Agardh, D. & Environmental Determinants of Diabetes in the Young (TEDDY) Group, E. D. O. D. I. T. Y. (. G., 2023, In: Diabetes Care. 46, 5, p. 1-5

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells

      Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Størling, Joachim & Mandrup-Poulsen, Thomas, Sep 2009, In: Endocrinology. 150, 9, p. 4094-103 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Inhibition of Nuclear Factor-kappa B or Bax Prevents Endoplasmic Reticulum Stress-But Not Nitric Oxide-Mediated Apoptosis in INS-1E Cells

      Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Storling, J. & Mandrup-Poulsen, Thomas, 2009, In: Endocrinology. 150, 9, p. 4094-4103 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Antitumorigenic effect of proteasome inhibitors on insulinoma cells.

      Størling, J., Allaman-Pillet, N., Karlsen, A. E., Billestrup, N., Bonny, C. & Mandrup-Poulsen, Thomas, 2004, In: Endocrinology. 146, 4, p. 1718-26 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Apolipoprotein CIII Reduces Proinflammatory Cytokine-Induced Apoptosis in Rat Pancreatic Islets via the Akt Prosurvival Pathway

      Størling, Joachim, Juntti-Berggren, L., Olivecrona, G., Prause, M. C., Berggren, P. & Mandrup-Poulsen, Thomas, 2011, In: Endocrinology. 152, 8, p. 3040-8 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells.

      Størling, J., Zaitsev, S. V., Kapelioukh, I. L., Karlsen, A. E., Billestrup, N., Berggren, P. & Mandrup-Poulsen, Thomas, 2005, In: Endocrinology. 146, 7, p. 3026-36 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Apolipoprotein CIII reduces proinflammatory cytokine-induced apoptosis in rat pancreatic islets via the Akt prosurvival pathway.

      Størling, Joachim, Juntti-Berggren, L., Olivecrona, G., Prause, Michala Cecilie Burstein, Berggren, P. & Mandrup-Poulsen, Thomas, Aug 2011, In: Endocrinology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt

      Størling, Joachim, Binzer, J., Andersson, A., Züllig, R. A., Tonnesen, M., Knudsen, R. L. P., Spinas, G. A., Sandler, S., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Oct 2005, In: Diabetologia. 48, 10, p. 2039-50 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Obesity-induced changes in gene expression in feline adipose and skeletal muscle tissue

      Jensen, Kathrine Stenberg, Novotny, G. W., Lutz, T. A., Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2023, In: Journal of Animal Physiology and Animal Nutrition. 107, 5, p. 1262 - 1278

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      The bimodal effect of interleukin 1 on rat pancreatic beta-cells--stimulation followed by inhibition--depends upon dose, duration of exposure, and ambient glucose concentration

      Spinas, G. A., Palmer, J. P., Mandrup-Poulsen, Thomas, Andersen, Heine, Nerup, J. & Nielsen, Jens Høiriis, Oct 1988, In: Acta Endocrinologica. 119, 2, p. 307-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans

      Spinas, G. A., Hansen, B. S., Linde, S., Kastern, W., Mølvig, J., Mandrup-Poulsen, Thomas, Dinarello, C. A., Nerup, J. & Nielsen, Jens Høiriis, Jul 1987, In: Diabetologia. 30, 7, p. 474-80 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Detrimental Actions of Chlorinated Nucleosides on the Function and Viability of Insulin-Producing Cells

      Sileikaite-Morvaközi, I., Hansen, W. H., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2023, In: International Journal of Molecular Sciences. 24, 19, 13 p., 14585.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      The role of RNA oxidation in islet dysfunction in Type 2 diabetes

      Sileikaite, I., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1 , p. S37-S38

      Research output: Contribution to journal › Conference abstract in journal › Research

    21. Published

      Mitophagy protects beta cells from inflammatory damage in diabetes

      Sidarala, V., Pearson, G. L., Parekh, V. S., Thompson, B., Christen, L., Gingerich, M. A., Zhu, J., Stromer, T., Ren, J., Reck, E. C., Chai, B., Corbett, J. A., Mandrup-Poulsen, Thomas, Satin, L. S. & Soleimanpour, S. A., 2020, In: JCI insight. 5, 24, 15 p., 141138.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The Fas pathway is involved in pancreatic beta cell secretory function.

      Schumann, D. M., Maedler, K., Franklin, I., Konrad, D., Størling, J., Böni-Schnetzler, M., Gjinovci, A., Kurrer, M. O., Gauthier, B. R., Bosco, D., Andres, A., Berney, T., Greter, M., Becher, B., Chervonsky, A. V., Halban, P. A., Mandrup-Poulsen, Thomas, Wollheim, C. B. & Donath, M. Y., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 8, p. 2861-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission

      Schloot, N. C., Hanifi-Moghaddam, P., Aabenhus-Andersen, N., Alizadeh, B. Z., Saha, M. T., Knip, M., Devendra, D., Wilkin, T., Bonifacio, E., Roep, B. O., Kolb, H. & Mandrup-Poulsen, Thomas, 2007, In: Diabetic Medicine. 24, 5, p. 512-520 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Diabetes and suppressors of cytokine signaling proteins.

      Rønn, S. G., Billestrup, N. & Mandrup-Poulsen, Thomas, 2007, In: Diabetes. 56, 2, p. 541-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection

      Rønn, S. G., Börjesson, A., Bruun, C., Heding, P. E., Frobøse, H., Mandrup-Poulsen, Thomas, Karlsen, A. E., Rasschaert, J., Sandler, S. & Billestrup, Nils, 2008, In: Diabetologia. 51, 10, p. 1873-1882 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 923693