Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor

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    1. Published

      Growth differences between North American and European children at risk for type 1 diabetes

      Nucci, A. M., Becker, D. J., Virtanen, S. M., Cuthbertson, D., Softness, B., Huot, C., Wasikowa, R., Dosch, H. M., Akerblom, H. K., Knip, M., TRIGR Study Group, T. S. G. & Mandrup-Poulsen, Thomas, Aug 2012, In: Pediatric Diabetes Online. 13, 5, p. 425-31 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      HDAC Inhibitor-Mediated Beta-Cell Protection Against Cytokine-Induced Toxicity Is STAT1 Tyr701 Phosphorylation Independent

      Dahllöf, M. S., Christensen, D. P., Harving, M., Wagner, B. K., Mandrup-Poulsen, Thomas & Lundh, M., 13 Jan 2015, In: Journal of Interferon & Cytokine Research. 35, 1, p. 63-70 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      HDAC3 inhibition rescues pancreatic beta cells from glucolipotoxicity and improves insulin secretion in obese diabetic rats

      Lundh, M., Galbo, T., Wagner, F. F., Christensen, D. P., Walpita, D., Gale, J. P., Zhang, Y., Hooker, J., Shulman, G. I., Mandrup-Poulsen, Thomas, Holson, E. B. & Wagner, B. K., Sep 2013, In: Diabetologia. 56, 1 suppl, p. S219-S219

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expression

      Fred, R. G., Bang-Berthelsen, C. H., Mandrup-Poulsen, Thomas, Grunnet, L. G. & Welsh, N., 2010, In: PLoS ONE. 5, 5, p. e10843

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus

      Christensen, D. P., Dahllöf, M. S., Lundh, M., Rasmussen, D. N., Nielsen, M. D., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 2011, In: Molecular Medicine. 17, 5-6, p. 378-90 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats

      Lundh, M., Galbo, T., Poulsen, Steen Seier & Mandrup-Poulsen, Thomas, Jul 2015, In: Diabetes, Obesity and Metabolism. 17, 7, p. 703-7 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    7. Published

      Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

      Lundh, M., Christensen, D. P., Damgaard Nielsen, M., Richardson, S. J., Dahllöf, M. S., Skovgaard, T., Berthelsen, J., Dinarello, C. A., Stevenazzi, A., Mascagni, P., Grunnet, Louise Groth, Morgan, N. G. & Mandrup-Poulsen, Thomas, 2012, In: Diabetologia. 55, 9, p. 2421-31

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial

      Knip, M., Åkerblom, H. K., Becker, D., Dosch, H., Dupre, J., Fraser, W., Howard, N., Ilonen, J., Krischer, J. P., Kordonouri, O., Lawson, M. L., Palmer, J. P., Savilahti, E., Vaarala, O., Virtanen, S. M., TRIGR Study Group, T. S. G. & Mandrup-Poulsen, Thomas, 11 Jun 2014, In: JAMA : the journal of the American Medical Association. 311, 22, p. 2279-87 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      IAPP boosts islet macrophage IL-1 in type 2 diabetes

      Mandrup-Poulsen, Thomas, 1 Oct 2010, In: Nature Immunology. 11, 10, p. 881-3 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      IL-1 beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

      Jacobsen, M. L. B., Ronn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Diabetologia. 52, 2, p. 281-288 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      IL-1 family nomenclature

      Dinarello, C., Arend, W., Sims, J., Smith, D., Blumberg, H., O'Neill, L., Goldbach-Mansky, R., Pizarro, T., Hoffman, H., Bufler, P., Nold, M., Ghezzi, P., Mantovani, A., Garlanda, C., Boraschi, D., Rubartelli, A., Netea, M., van der Meer, J., Joosten, L., Mandrup-Poulsen, T. & 14 others, Donath, M., Lewis, E., Pfeilschifter, J., Martin, M., Kracht, M., Muehl, H., Novick, D., Lukic, M., Conti, B., Solinger, A., Kelk, P., Peyman, K., van de Veerdonk, F. & Gabel, C., 1 Nov 2010, In: Nature Immunology. 11, 11, p. 973 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      IL-1 receptor antagonism and muscle gene expression in patients with type 2 diabetes

      Berchtold, L. A., Larsen, C. M., Vaag, Allan, Faulenbach, M., Workman, C. T., Kruhøffer, M., Donath, M. & Mandrup-Poulsen, Thomas, 2009, In: European Cytokine Network. 20, 2, p. 81-87 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      IL-1β-induced pro-apoptotic signaling is facilitated by NCAM/FGF receptor signaling and inhibited by the C3d ligand in the INS-1E rat beta cell line

      Petersen, L. G., Størling, J., Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, N., Bock, E. M. & Mandrup-Poulsen, Thomas, 2006, In: Diabetologia. 49, p. 1864-75

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

      Jacobsen, M. L. B., Rønn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2008, In: Diabetologia. 52, 2, p. 281-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line

      Petersen, L. G., Størling, Joachim, Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, Nils, Bock, E. & Mandrup-Poulsen, Thomas, 2006, In: Diabetologia. 49, 8, p. 1864-75 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Identification of a type 1 diabetes-associated CD4 promoter haplotype with high constitutive activity

      Kristiansen, O. P., Karlsen, A. E., Larsen, Z. M., Johannesen, Jesper, Pociot, Flemming, Mandrup-Poulsen, Thomas & Danish IDDM Epidemiology and Genetics Group and Danish Study Group of IDDM in Childhood, D. I. E. A. G. G. A. D. S. G. O. I. I. C., 1 Jun 2004, In: Scandinavian Journal of Immunology. 59, 6, p. 582-91 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Immunometabolism in 2017: Metabolism and the inflammasome in health and ageing

      Mandrup-Poulsen, Thomas, Feb 2018, In: Nature Reviews Endocrinology. 14, 2, p. 72-74 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Increased Plasma Ferritin Concentration and Low-Grade Inflammation-A Mendelian Randomization Study

      Moen, I. W., Bergholdt, H. K. M., Mandrup-Poulsen, Thomas, Nordestgaard, Børge & Ellervik, Christina, 2018, In: Clinical Chemistry. 64, 2, p. 374-385 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J Mice

      Fjære, E., Aune, U. L., Røen, K., Keenan, A. H., Ma, Tao, Borkowski, K., Kristensen, D. M. B., Novotny, G. W., Mandrup-Poulsen, Thomas, Hudson, B. D., Milligan, G., Xi, Y., Newman, J. W., Haj, F. G., Liaset, B., Kristiansen, Karsten & Madsen, L., 2014, In: The Journal of Biological Chemistry. 289, 23, p. 16032-16045 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Inflammatory and metabolic stress perturbs the beta cell circadian clock: [Meeting Abstract]

      Andersen, Phillip Alexander Keller, Rose, P. H., Koomen, M., Petrenko, V., Dahlby, T., Ghiasi, S. M., Dibner, C. & Mandrup-Poulsen, Thomas, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S120-S120 237.

      Research output: Contribution to journal › Conference abstract in journal › Research

    21. Published

      Inhibition of Nuclear Factor-kappa B or Bax Prevents Endoplasmic Reticulum Stress-But Not Nitric Oxide-Mediated Apoptosis in INS-1E Cells

      Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Storling, J. & Mandrup-Poulsen, Thomas, 2009, In: Endocrinology. 150, 9, p. 4094-4103 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Inhibition of beta cell growth and function by bone morphogenetic proteins

      Bruun, C., Christensen, G. L., Jacobsen, M. L. B., Kanstrup, M. B., Jensen, P. R., Fjordvang, H., Mandrup-Poulsen, Thomas & Billestrup, Nils, 27 Sep 2014, In: Diabetologia. 57, 12, p. 2546-54 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

      Larsen, L., Tonnesen, M., Ronn, S. G., Størling, Joachim, Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, Nils & Mandrup-Poulsen, Thomas, Apr 2007, In: Diabetologia. 50, 4, p. 779-89 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

      Larsen, L., Tonnesen, M. F., Ronn, S. G., Storling, J., Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, N. & Mandrup-Poulsen, Thomas, 2007, In: Diabetologia. 50, 4, p. 779-789 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells

      Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Størling, Joachim & Mandrup-Poulsen, Thomas, Sep 2009, In: Endocrinology. 150, 9, p. 4094-103 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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