Lærke Smidt Gasbjerg
Postdoc, Assistant Professor
Molecular and Translational Pharmacology
Blegdamsvej 3, 2200 København N.
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2012
- Published
Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice
Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Biased and Constitutive Signaling in the CC-Chemokine Receptor CCR5 by manipulating the Interface between Transmembrane Helix 6 and 7
Steen, A., Thiele, S., Guo, D., Gasbjerg, Lærke Smidt, Frimurer, Thomas Michael & Rosenkilde, Mette, 3 May 2013, In: Journal of Biological Chemistry. 288, 18, p. 12511-12521 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular Disulfide Bridges Serve Different Purposes in Two Homologous Chemokine Receptors, CCR1 and CCR5
Rummel, P. C., Thiele, S., Gasbjerg, Lærke Smidt, Petersen, T. P., wbf943, wbf943, Ulven, T. & Rosenkilde, Mette, 13 Jun 2013, In: Current Molecular Pharmacology. 84, 3, p. 335-345 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors
wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release
wbf943, wbf943, Gabe, M. N., Gasbjerg, Lærke Smidt, Christiansen, Charlotte Bayer, Svendsen, B., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2017, In: Biochemical Pharmacology. 131, p. 78-88Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signaling via G proteins mediates tumorigenic effects of GPR87
Arfelt, K. N., Fares, S., wbf943, wbf943, Hjortø, Gertrud Malene, Gasbjerg, Lærke Smidt, Molleskov-Jensen, A., Benned-Jensen, T. & Rosenkilde, Mette, Jan 2017, In: Cellular Signalling. 30, p. 9-18Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor
Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, , Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Intracoronary and Intravenous Melatonin on Myocardial Salvage Index in Patients with ST-Elevation Myocardial Infarction: a Randomized Placebo Controlled Trial
Ekeloef, S., Halladin, N., Fonnes, S., Jensen, S. E., Zaremba, T., Rosenberg, Jacob, Jonsson, G., Aarøe, J., Gasbjerg, Lærke Smidt, Rosenkilde, Mette & Gögenur, Ismail, Dec 2017, In: Journal of Cardiovascular Translational Research. 10, 5-6, p. 470-479 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption
Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects
Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling
Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The Combination of Fosfomycin, Metronidazole, and Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor is Stable in vitro and Has Maintained Antibacterial Activity
Fonnes, S., Holzknecht, Barbara Juliane, Gasbjerg, Lærke Smidt, Weisser, J. J., Hallberg, H. W., Arpi, M. & Rosenberg, Jacob, 2018, In: Drug Research. 68, 6, p. 349-354Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Ethanol on Inflammation Markers and FGF-21 in Healthy Individuals
Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Møller, H., Gillum, M., Gronbaek, H., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes. 67, Supplement 1, 2415-PUB.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of the incretins in the postprandial bone remodelling
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors
Gabe, M. B. N., Sparre-Ulrich, A. H., Pedersen, M. F., Gasbjerg, Lærke Smidt, Inoue, A., Bräuner, Hans, Hartmann, Bolette & Rosenkilde, M. M., 31 Jan 2018, In: Biochemical Pharmacology. 150, p. 97-107 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study
Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents
Gasbjerg, Lærke Smidt, Gabe, M. B. N., Hartmann, Bolette, Christensen, Mikkel Bring, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Feb 2018, In: Peptides. 100, p. 173-181Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes
Brønden, A., Albér, A., Rohde, U., Gasbjerg, Lærke Smidt, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetes, Obesity and Metabolism. 20, 2, p. 362-369Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweight/obese individuals: a randomised, crossover study
Bergmann, N. C., Lund, A., Gasbjerg, Lærke Smidt, Meessen, E. C. E., Andersen, M. M., Bergmann, S., Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Diabetologia. 62, 4, p. 665-675 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous glucose-dependent insulinotropic polypeptide exerts diverging and tissue specific in obese patients with type 2 diabetes
Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., wbf943, wbf943, Skov-Jeppesen, Kirsa, Jensen, M. H., Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, M. B. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S270-S271 2 p., 560.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
GLP-2 and GIP exert separate effects on bone turnover: A randomized, placebo-controlled, crossover study in healthy young men
Skov-Jeppesen, Kirsa, Svane, M. S., Martinussen, C., Gabe, M. B. N., Gasbjerg, Lærke Smidt, Veedfald, Simon, Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2019, In: Bone. 125, p. 178-185Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gluco-metabolic effects of oral and intravenous alcohol administration in men
Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Bergmann, S., Heisted, M. M., Gillum, M. P., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Endocrine Connections. 8, 10, p. 1372-1382Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats
Baidassano, S., Gasbjerg, Lærke Smidt, Kizilkaya, Hüsün Sheyma, Rosenkilde, Mette, Holst, Jens Juul & Hartmann, Bolette, 2019, In: Frontiers in Endocrinology. 10, 11 p., 492.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals
Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Jensen, M. H., Gabe, M. B. N., wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2019, In: Diabetes. 68, 3, p. 906-917Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37775779
Most downloads
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304
downloads
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
299
downloads
GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
139
downloads
Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats
Research output: Contribution to journal › Journal article › Research › peer-review
Published