A long-term follow-up study of the Hand Eczema Trial (HET): a randomized clinical trial of a secondary preventive programme introduced to Danish healthcare workers
Research output: Contribution to journal › Journal article › Research › peer-review
Background. Preventive skin care programmes have shown beneficial effects on the prevalence and severity of hand eczema, but most trials only report short-term outcomes. One such trial was the randomized Hand Eczema Trial (HET, 2009) investigating the effects of a secondary prevention programme in healthcare workers. Positive results have been reported at 5-month follow-up.
Objectives. To examine the long-term (42-47 months) effects of the HET.
Methods. The present study was a follow-up questionnaire study on the effect of the intervention. Outcomes were the presence and severity of hand eczema, health-related quality of life (HR-QoL), skin protective behaviour, and knowledge of skin protection. A supplementary outcome was general improvement/worsening of hand eczema.
Results. Comparison of the outcomes at follow-up showed no marked differences between the two groups. General improvement was reported by 70% in the intervention group and by 54% in the control group (p=0.25). A small, statistically significant improvement was found regarding HR-QoL in the intervention group only (p=0.015).
Conclusions. The impact of an intervention that is effective after 5 months is attenuated over time, with no long-term effect on the outcomes examined. We suggest that skin care education should be repeated at regular intervals
Objectives. To examine the long-term (42-47 months) effects of the HET.
Methods. The present study was a follow-up questionnaire study on the effect of the intervention. Outcomes were the presence and severity of hand eczema, health-related quality of life (HR-QoL), skin protective behaviour, and knowledge of skin protection. A supplementary outcome was general improvement/worsening of hand eczema.
Results. Comparison of the outcomes at follow-up showed no marked differences between the two groups. General improvement was reported by 70% in the intervention group and by 54% in the control group (p=0.25). A small, statistically significant improvement was found regarding HR-QoL in the intervention group only (p=0.015).
Conclusions. The impact of an intervention that is effective after 5 months is attenuated over time, with no long-term effect on the outcomes examined. We suggest that skin care education should be repeated at regular intervals
Original language | English |
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Journal | Contact Dermatitis |
Volume | 78 |
Issue number | 5 |
Pages (from-to) | 329-334 |
ISSN | 0105-1873 |
DOIs | |
Publication status | Published - May 2018 |
- hand dermatitis, hand eczema, long-term follow-up, occupational hand dermatitis, occupational skin diasease, prevention programme, randomized clinical trial, secondary prevention programme
Research areas
ID: 215787623