The variability of 2D and 3D transthoracic echocardiography applied in a general population: Intermodality, inter- and intraobserver variability
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The variability of 2D and 3D transthoracic echocardiography applied in a general population : Intermodality, inter- and intraobserver variability. / Lyng Lindgren, Filip; Tayal, Bhupendar; Bundgaard Ringgren, Kristian; Ascanius Jacobsen, Peter; Hay Kragholm, Kristian; Zaremba, Tomas; Holmark Andersen, Niels; Møgelvang, Rasmus; Biering-Sørensen, Tor; Hagendorff, Andreas; Schnohr, Peter; Jensen, Gorm; Søgaard, Peter.
In: International Journal of Cardiovascular Imaging, Vol. 38, No. 10, 2022, p. 2177–2190.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The variability of 2D and 3D transthoracic echocardiography applied in a general population
T2 - Intermodality, inter- and intraobserver variability
AU - Lyng Lindgren, Filip
AU - Tayal, Bhupendar
AU - Bundgaard Ringgren, Kristian
AU - Ascanius Jacobsen, Peter
AU - Hay Kragholm, Kristian
AU - Zaremba, Tomas
AU - Holmark Andersen, Niels
AU - Møgelvang, Rasmus
AU - Biering-Sørensen, Tor
AU - Hagendorff, Andreas
AU - Schnohr, Peter
AU - Jensen, Gorm
AU - Søgaard, Peter
N1 - Publisher Copyright: © 2022, The Author(s), under exclusive licence to Springer Nature B.V.
PY - 2022
Y1 - 2022
N2 - Assessment of the left ventricular (LV) function by three-dimensional echocardiography (3DE) is potentially superior to 2D echo echocardiography (2DE) for LV performance assessment. However, intra- and interobserver variation needs further investigation. We examined the intra- and interobserver variability between 2 and 3DE in a general population. In total, 150 participants from the Copenhagen City Heart Study were randomly chosen. Two observers assessed left ventricular ejection fraction (LVEF), end-diastolic (EDV) and end-systolic volumes (ESV) by 2DE and 3DE. Inter-, intraobserver and intermodality variabilities are presented as means of difference (MD), limits of agreement (LoA), coefficient of correlation (r), intraclass correlation coefficients (ICC). The lowest MD and LoA and highest r- and ICC-values was generally seen among the 3D acquisitions, with the 3D EDV interobserver as the best performing estimate (r = 0.95, ICC = 0.94). The largest MD, LoA and lowest r- and ICC-values was found in the interobserver 2D LVEF (r = 0.76, ICC = 0.63. For the intraobserver analysis, there were statistically significant differences between observations for all but 3DE EDV (p = 0.06). For interobserver analysis, there were statistically significant differences between observers for all estimates but 2DE EDV (p = 0.11), 3D ejection fraction (p = 0.9), 3DE EDV (p = 0.11) and 3D ESV (p = 0.15). Three-dimensional echocardiography is more robust and reproducible than 2DE and should be preferred for assessment of LV function.
AB - Assessment of the left ventricular (LV) function by three-dimensional echocardiography (3DE) is potentially superior to 2D echo echocardiography (2DE) for LV performance assessment. However, intra- and interobserver variation needs further investigation. We examined the intra- and interobserver variability between 2 and 3DE in a general population. In total, 150 participants from the Copenhagen City Heart Study were randomly chosen. Two observers assessed left ventricular ejection fraction (LVEF), end-diastolic (EDV) and end-systolic volumes (ESV) by 2DE and 3DE. Inter-, intraobserver and intermodality variabilities are presented as means of difference (MD), limits of agreement (LoA), coefficient of correlation (r), intraclass correlation coefficients (ICC). The lowest MD and LoA and highest r- and ICC-values was generally seen among the 3D acquisitions, with the 3D EDV interobserver as the best performing estimate (r = 0.95, ICC = 0.94). The largest MD, LoA and lowest r- and ICC-values was found in the interobserver 2D LVEF (r = 0.76, ICC = 0.63. For the intraobserver analysis, there were statistically significant differences between observations for all but 3DE EDV (p = 0.06). For interobserver analysis, there were statistically significant differences between observers for all estimates but 2DE EDV (p = 0.11), 3D ejection fraction (p = 0.9), 3DE EDV (p = 0.11) and 3D ESV (p = 0.15). Three-dimensional echocardiography is more robust and reproducible than 2DE and should be preferred for assessment of LV function.
KW - Cardiac imaging techniques
KW - Health surveys
KW - Heart failure
KW - Left ventricular function
KW - Urban population
U2 - 10.1007/s10554-022-02618-8
DO - 10.1007/s10554-022-02618-8
M3 - Journal article
C2 - 37726455
AN - SCOPUS:85128706888
VL - 38
SP - 2177
EP - 2190
JO - International Journal of Cardiovascular Imaging
JF - International Journal of Cardiovascular Imaging
SN - 1569-5794
IS - 10
ER -
ID: 317940384