The mechanism of gastrin release in cysteamine-induced duodenal ulcer

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Standard

The mechanism of gastrin release in cysteamine-induced duodenal ulcer. / Poulsen, Steen Seier.

In: Scandinavian Journal of Gastroenterology, Vol. 17, No. 5, 08.1982, p. 609-12.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Poulsen, SS 1982, 'The mechanism of gastrin release in cysteamine-induced duodenal ulcer', Scandinavian Journal of Gastroenterology, vol. 17, no. 5, pp. 609-12.

APA

Poulsen, S. S. (1982). The mechanism of gastrin release in cysteamine-induced duodenal ulcer. Scandinavian Journal of Gastroenterology, 17(5), 609-12.

Vancouver

Poulsen SS. The mechanism of gastrin release in cysteamine-induced duodenal ulcer. Scandinavian Journal of Gastroenterology. 1982 Aug;17(5):609-12.

Author

Poulsen, Steen Seier. / The mechanism of gastrin release in cysteamine-induced duodenal ulcer. In: Scandinavian Journal of Gastroenterology. 1982 ; Vol. 17, No. 5. pp. 609-12.

Bibtex

@article{c9dbe4545d7e4b0982f894c8d6e841e1,
title = "The mechanism of gastrin release in cysteamine-induced duodenal ulcer",
abstract = "Duodenal ulcer can be induced in rats by a single dose of cysteamine. The ulcer formation is accompanied by acid hypersecretion and elevated serum gastrin levels. This study was performed to elucidate the mechanisms of gastrin release after an ulcerogenic dose of cysteamine. Cysteamine induced a rise in serum gastrin from 29 +/- 5 pg/ml to a maximum of 203 +/- 62 pg/ml after 3 h in unoperated rats, whereas no rise was seen in vagotomized or antrectomized rats. The beta-adrenergic blocking agent propranolol strongly inhibited cysteamine-induced gastrin release, whereas atropine dependent on an intact vagus and may be mediated by beta-adrenergic receptors.",
keywords = "Animals, Atropine, Cysteamine, Duodenal Ulcer, Female, Gastrins, Propranolol, Rats, Rats, Inbred Strains",
author = "Poulsen, {Steen Seier}",
year = "1982",
month = aug,
language = "English",
volume = "17",
pages = "609--12",
journal = "Scandinavian Journal of Gastroenterology",
issn = "0036-5521",
publisher = "Taylor & Francis",
number = "5",

}

RIS

TY - JOUR

T1 - The mechanism of gastrin release in cysteamine-induced duodenal ulcer

AU - Poulsen, Steen Seier

PY - 1982/8

Y1 - 1982/8

N2 - Duodenal ulcer can be induced in rats by a single dose of cysteamine. The ulcer formation is accompanied by acid hypersecretion and elevated serum gastrin levels. This study was performed to elucidate the mechanisms of gastrin release after an ulcerogenic dose of cysteamine. Cysteamine induced a rise in serum gastrin from 29 +/- 5 pg/ml to a maximum of 203 +/- 62 pg/ml after 3 h in unoperated rats, whereas no rise was seen in vagotomized or antrectomized rats. The beta-adrenergic blocking agent propranolol strongly inhibited cysteamine-induced gastrin release, whereas atropine dependent on an intact vagus and may be mediated by beta-adrenergic receptors.

AB - Duodenal ulcer can be induced in rats by a single dose of cysteamine. The ulcer formation is accompanied by acid hypersecretion and elevated serum gastrin levels. This study was performed to elucidate the mechanisms of gastrin release after an ulcerogenic dose of cysteamine. Cysteamine induced a rise in serum gastrin from 29 +/- 5 pg/ml to a maximum of 203 +/- 62 pg/ml after 3 h in unoperated rats, whereas no rise was seen in vagotomized or antrectomized rats. The beta-adrenergic blocking agent propranolol strongly inhibited cysteamine-induced gastrin release, whereas atropine dependent on an intact vagus and may be mediated by beta-adrenergic receptors.

KW - Animals

KW - Atropine

KW - Cysteamine

KW - Duodenal Ulcer

KW - Female

KW - Gastrins

KW - Propranolol

KW - Rats

KW - Rats, Inbred Strains

M3 - Journal article

C2 - 7178823

VL - 17

SP - 609

EP - 612

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

SN - 0036-5521

IS - 5

ER -

ID: 47489621