Systemically administered trefoil factors are secreted into the gastric lumen and increase the viscosity of gastric contents
Research output: Contribution to journal › Journal article › Research › peer-review
Trefoil factors (TFFs) secreted by mucus-producing cells are essential for the defence of the gastrointestinal mucosa. TFFs probably influence the viscoelastic properties of mucus, but this has not been demonstrated in vivo. We therefore studied the gastric secretion of systemically administered TFF2 and TFF3, and their influence on the viscosity of the secretions.
| Original language | English |
|---|---|
| Journal | British Journal of Pharmacology |
| Volume | 149 |
| Issue number | 1 |
| Pages (from-to) | 92-99 |
| Number of pages | 8 |
| ISSN | 0007-1188 |
| DOIs | |
| Publication status | Published - 2006 |
- Animals, Autoradiography, Enzyme-Linked Immunosorbent Assay, Female, Gastrointestinal Contents, Immunohistochemistry, In Situ Hybridization, Injections, Intravenous, Mice, Mice, Inbred C57BL, Peptides, Rats, Rats, Wistar, Stomach, Tissue Distribution, Viscosity
Research areas
ID: 1203034