Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance

Research output: Contribution to journalJournal articleResearchpeer-review

Glucose tolerance and skeletal muscle coenzyme Q(10) (Q(10)) content, mitochondrial density, and mitochondrial oxidative phosphorylation (OXPHOS) capacity were measured in simvastatin-treated patients (n = 10) and in well-matched control subjects (n = 9).
Original languageEnglish
JournalJournal of the American College of Cardiology
Issue number1
Pages (from-to)44-53
Number of pages10
Publication statusPublished - 8 Jan 2013

    Research areas

  • Blood Glucose, Case-Control Studies, Cell Respiration, Electron Transport, Electron Transport Complex I, Electron Transport Complex II, Glucose Intolerance, Glucose Tolerance Test, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Insulin Resistance, Male, Middle Aged, Mitochondria, Muscle, Muscle Fibers, Skeletal, Muscle, Skeletal, Oxidative Phosphorylation, Simvastatin, Ubiquinone

ID: 44914633