Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance
Research output: Contribution to journal › Journal article › peer-review
Glucose tolerance and skeletal muscle coenzyme Q(10) (Q(10)) content, mitochondrial density, and mitochondrial oxidative phosphorylation (OXPHOS) capacity were measured in simvastatin-treated patients (n = 10) and in well-matched control subjects (n = 9).
|Journal||Journal of the American College of Cardiology|
|Number of pages||10|
|Publication status||Published - 8 Jan 2013|
- Blood Glucose, Case-Control Studies, Cell Respiration, Electron Transport, Electron Transport Complex I, Electron Transport Complex II, Glucose Intolerance, Glucose Tolerance Test, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Insulin Resistance, Male, Middle Aged, Mitochondria, Muscle, Muscle Fibers, Skeletal, Muscle, Skeletal, Oxidative Phosphorylation, Simvastatin, Ubiquinone