Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo

Research output: Contribution to journalJournal articleResearchpeer-review

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Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo. / Spiess, Katja; Jeppesen, Mads G.; Malmgaard-Clausen, Mikkel; Krzywkowski, Karen; Dulal, Kalpana; Cheng, Tong; Hjorto, Gertrud M.; Larsen, Olav; Burg, John S.; Jarvis, Michael A.; Garcia, K. Christopher; Zhu, Hua; Kledal, Thomas N.; Rosenkilde, Mette M.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, No. 27, 07.2015, p. 8427-8432.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Spiess, K, Jeppesen, MG, Malmgaard-Clausen, M, Krzywkowski, K, Dulal, K, Cheng, T, Hjorto, GM, Larsen, O, Burg, JS, Jarvis, MA, Garcia, KC, Zhu, H, Kledal, TN & Rosenkilde, MM 2015, 'Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo', Proceedings of the National Academy of Sciences of the United States of America, vol. 112, no. 27, pp. 8427-8432. https://doi.org/10.1073/pnas.1509392112

APA

Spiess, K., Jeppesen, M. G., Malmgaard-Clausen, M., Krzywkowski, K., Dulal, K., Cheng, T., Hjorto, G. M., Larsen, O., Burg, J. S., Jarvis, M. A., Garcia, K. C., Zhu, H., Kledal, T. N., & Rosenkilde, M. M. (2015). Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo. Proceedings of the National Academy of Sciences of the United States of America, 112(27), 8427-8432. https://doi.org/10.1073/pnas.1509392112

Vancouver

Spiess K, Jeppesen MG, Malmgaard-Clausen M, Krzywkowski K, Dulal K, Cheng T et al. Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2015 Jul;112(27):8427-8432. https://doi.org/10.1073/pnas.1509392112

Author

Spiess, Katja ; Jeppesen, Mads G. ; Malmgaard-Clausen, Mikkel ; Krzywkowski, Karen ; Dulal, Kalpana ; Cheng, Tong ; Hjorto, Gertrud M. ; Larsen, Olav ; Burg, John S. ; Jarvis, Michael A. ; Garcia, K. Christopher ; Zhu, Hua ; Kledal, Thomas N. ; Rosenkilde, Mette M. / Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo. In: Proceedings of the National Academy of Sciences of the United States of America. 2015 ; Vol. 112, No. 27. pp. 8427-8432.

Bibtex

@article{31b48c5cda0d46f5af52807702c412e8,
title = "Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo",
keywords = "HCMV, 7TM GPCR, protein engineering, antiviral drug, chemokine",
author = "Katja Spiess and Jeppesen, {Mads G.} and Mikkel Malmgaard-Clausen and Karen Krzywkowski and Kalpana Dulal and Tong Cheng and Hjorto, {Gertrud M.} and Olav Larsen and Burg, {John S.} and Jarvis, {Michael A.} and Garcia, {K. Christopher} and Hua Zhu and Kledal, {Thomas N.} and Rosenkilde, {Mette M.}",
year = "2015",
month = jul,
doi = "10.1073/pnas.1509392112",
language = "English",
volume = "112",
pages = "8427--8432",
journal = "Proceedings of the National Academy of Sciences of the United States of America",
issn = "0027-8424",
publisher = "The National Academy of Sciences of the United States of America",
number = "27",

}

RIS

TY - JOUR

T1 - Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo

AU - Spiess, Katja

AU - Jeppesen, Mads G.

AU - Malmgaard-Clausen, Mikkel

AU - Krzywkowski, Karen

AU - Dulal, Kalpana

AU - Cheng, Tong

AU - Hjorto, Gertrud M.

AU - Larsen, Olav

AU - Burg, John S.

AU - Jarvis, Michael A.

AU - Garcia, K. Christopher

AU - Zhu, Hua

AU - Kledal, Thomas N.

AU - Rosenkilde, Mette M.

PY - 2015/7

Y1 - 2015/7

KW - HCMV

KW - 7TM GPCR

KW - protein engineering

KW - antiviral drug

KW - chemokine

U2 - 10.1073/pnas.1509392112

DO - 10.1073/pnas.1509392112

M3 - Journal article

C2 - 26080445

VL - 112

SP - 8427

EP - 8432

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

SN - 0027-8424

IS - 27

ER -

ID: 160924382