Protein carbamylation: a key driver of vascular calcification during chronic kidney disease

Research output: Contribution to journal › Comment/debate › Research › peer-review

Standard

Protein carbamylation : a key driver of vascular calcification during chronic kidney disease. / Hawkins, Clare L.

In: Kidney International, Vol. 94, No. 1, 2018, p. 12-14.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Harvard

Hawkins, CL 2018, 'Protein carbamylation: a key driver of vascular calcification during chronic kidney disease', Kidney International, vol. 94, no. 1, pp. 12-14. https://doi.org/10.1016/j.kint.2018.03.022

APA

Hawkins, C. L. (2018). Protein carbamylation: a key driver of vascular calcification during chronic kidney disease. Kidney International, 94(1), 12-14. https://doi.org/10.1016/j.kint.2018.03.022

Vancouver

Hawkins CL. Protein carbamylation: a key driver of vascular calcification during chronic kidney disease. Kidney International. 2018;94(1):12-14. https://doi.org/10.1016/j.kint.2018.03.022

Author

Hawkins, Clare L. / Protein carbamylation : a key driver of vascular calcification during chronic kidney disease. In: Kidney International. 2018 ; Vol. 94, No. 1. pp. 12-14.

Bibtex

@article{89f2d94ff5aa47efb1c556c6c5ea1b1c,
title = "Protein carbamylation: a key driver of vascular calcification during chronic kidney disease",
abstract = "Vascular calcification is a frequent complication of advanced chronic kidney disease. Protein carbamylation is implicated in the acceleration of vascular disease in chronic kidney disease, but the mechanisms are not clear. Mori et al. report that protein carbamylation exacerbates vascular calcification by decreasing ectonucleotide pyrophosphate/phosphodiesterase 1 expression, owing to carbamylation of mitochondrial proteins and oxidative stress. This provides new insight into the pathways responsible for calcification in chronic kidney disease.",
author = "Hawkins, {Clare L.}",
year = "2018",
doi = "10.1016/j.kint.2018.03.022",
language = "English",
volume = "94",
pages = "12--14",
journal = "Kidney International",
issn = "0085-2538",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Protein carbamylation

T2 - a key driver of vascular calcification during chronic kidney disease

AU - Hawkins, Clare L.

PY - 2018

Y1 - 2018

N2 - Vascular calcification is a frequent complication of advanced chronic kidney disease. Protein carbamylation is implicated in the acceleration of vascular disease in chronic kidney disease, but the mechanisms are not clear. Mori et al. report that protein carbamylation exacerbates vascular calcification by decreasing ectonucleotide pyrophosphate/phosphodiesterase 1 expression, owing to carbamylation of mitochondrial proteins and oxidative stress. This provides new insight into the pathways responsible for calcification in chronic kidney disease.

AB - Vascular calcification is a frequent complication of advanced chronic kidney disease. Protein carbamylation is implicated in the acceleration of vascular disease in chronic kidney disease, but the mechanisms are not clear. Mori et al. report that protein carbamylation exacerbates vascular calcification by decreasing ectonucleotide pyrophosphate/phosphodiesterase 1 expression, owing to carbamylation of mitochondrial proteins and oxidative stress. This provides new insight into the pathways responsible for calcification in chronic kidney disease.

U2 - 10.1016/j.kint.2018.03.022

DO - 10.1016/j.kint.2018.03.022

M3 - Comment/debate

C2 - 29933841

VL - 94

SP - 12

EP - 14

JO - Kidney International

JF - Kidney International

SN - 0085-2538

IS - 1

ER -

ID: 213163448