Pathophysiology, risk, diagnosis, and management of venous thrombosis in space: where are we now?
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Pathophysiology, risk, diagnosis, and management of venous thrombosis in space : where are we now? / Harris, Katie M.; Arya, Roopen; Elias, Antoine; Weber, Tobias; Green, David A.; Greaves, Danielle K.; Petersen, Lonnie G.; Roberts, Lara; Kamine, Tovy Haber; Mazzolai, Lucia; Bergauer, Andrej; Kim, David S.; Olde Engberink, Rik H.; zu Eulenberg, Peter; Grassi, Bruno; Zuccarelli, Lucrezia; Baldassarre, Giovanni; Tabury, Kevin; Baatout, Sarah; Jordan, Jens; Blaber, Andrew P.; Choukér, Alexander; Russomano, Thais; Goswami, Nandu.
In: npj Microgravity, Vol. 9, No. 1, 17, 2023.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Pathophysiology, risk, diagnosis, and management of venous thrombosis in space
T2 - where are we now?
AU - Harris, Katie M.
AU - Arya, Roopen
AU - Elias, Antoine
AU - Weber, Tobias
AU - Green, David A.
AU - Greaves, Danielle K.
AU - Petersen, Lonnie G.
AU - Roberts, Lara
AU - Kamine, Tovy Haber
AU - Mazzolai, Lucia
AU - Bergauer, Andrej
AU - Kim, David S.
AU - Olde Engberink, Rik H.
AU - zu Eulenberg, Peter
AU - Grassi, Bruno
AU - Zuccarelli, Lucrezia
AU - Baldassarre, Giovanni
AU - Tabury, Kevin
AU - Baatout, Sarah
AU - Jordan, Jens
AU - Blaber, Andrew P.
AU - Choukér, Alexander
AU - Russomano, Thais
AU - Goswami, Nandu
N1 - Publisher Copyright: © 2023, The Author(s).
PY - 2023
Y1 - 2023
N2 - The recent incidental discovery of an asymptomatic venous thrombosis (VT) in the internal jugular vein of an astronaut on the International Space Station prompted a necessary, immediate response from the space medicine community. The European Space Agency formed a topical team to review the pathophysiology, risk and clinical presentation of venous thrombosis and the evaluation of its prevention, diagnosis, mitigation, and management strategies in spaceflight. In this article, we discuss the findings of the ESA VT Topical Team over its 2-year term, report the key gaps as we see them in the above areas which are hindering understanding VT in space. We provide research recommendations in a stepwise manner that build upon existing resources, and highlight the initial steps required to enable further evaluation of this newly identified pertinent medical risk.
AB - The recent incidental discovery of an asymptomatic venous thrombosis (VT) in the internal jugular vein of an astronaut on the International Space Station prompted a necessary, immediate response from the space medicine community. The European Space Agency formed a topical team to review the pathophysiology, risk and clinical presentation of venous thrombosis and the evaluation of its prevention, diagnosis, mitigation, and management strategies in spaceflight. In this article, we discuss the findings of the ESA VT Topical Team over its 2-year term, report the key gaps as we see them in the above areas which are hindering understanding VT in space. We provide research recommendations in a stepwise manner that build upon existing resources, and highlight the initial steps required to enable further evaluation of this newly identified pertinent medical risk.
UR - http://www.scopus.com/inward/record.url?scp=85148463768&partnerID=8YFLogxK
U2 - 10.1038/s41526-023-00260-9
DO - 10.1038/s41526-023-00260-9
M3 - Review
C2 - 36797288
AN - SCOPUS:85148463768
VL - 9
JO - npj Microgravity
JF - npj Microgravity
SN - 2373-8065
IS - 1
M1 - 17
ER -
ID: 337978959