Neuroendokrin aktivering ved hjerteinsufficiens II: Kan diagnosen stilles og prognosen vurderes med en blodprove?
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Neuroendokrin aktivering ved hjerteinsufficiens II : Kan diagnosen stilles og prognosen vurderes med en blodprove? / Kjaer, A.
In: Ugeskrift for Laeger, Vol. 162, No. 44, 30.10.2000, p. 5910-5913.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Neuroendokrin aktivering ved hjerteinsufficiens II
T2 - Kan diagnosen stilles og prognosen vurderes med en blodprove?
AU - Kjaer, A.
PY - 2000/10/30
Y1 - 2000/10/30
N2 - Neurohumoral systems activated in heart failure are reviewed in relation to prognostic and diagnostic information. Plasma levels of noradrenaline, renin, vasopressin, endothelin-1, ANP, BNP, and TNF-α are all elevated in heart failure. Most of these factors correlate with the prognosis, but only a minor part seems to posses additional, independent information when other information that is normally available in such patients is taken into account. At present, the diagnosis of heart failure cannot be made on only one blood sample. However, neuroendocrine markers seem: 1) to have a role in the diagnosis and classification of heart failure, 2) to be useful in providing a 'neuroendocrine profile', which elucidates different aspects of heart failure, and 3) to be of probable value in the choice and titration of medical treatment for the individual patient in the future.
AB - Neurohumoral systems activated in heart failure are reviewed in relation to prognostic and diagnostic information. Plasma levels of noradrenaline, renin, vasopressin, endothelin-1, ANP, BNP, and TNF-α are all elevated in heart failure. Most of these factors correlate with the prognosis, but only a minor part seems to posses additional, independent information when other information that is normally available in such patients is taken into account. At present, the diagnosis of heart failure cannot be made on only one blood sample. However, neuroendocrine markers seem: 1) to have a role in the diagnosis and classification of heart failure, 2) to be useful in providing a 'neuroendocrine profile', which elucidates different aspects of heart failure, and 3) to be of probable value in the choice and titration of medical treatment for the individual patient in the future.
UR - http://www.scopus.com/inward/record.url?scp=0034735418&partnerID=8YFLogxK
M3 - Review
C2 - 11094550
AN - SCOPUS:0034735418
VL - 162
SP - 5910
EP - 5913
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 44
ER -
ID: 283515812