Hyperlaktatæmi
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Hyperlaktatæmi. / Berg, Ronan Mg; Jeppesen, Troels E; Mohammad, Milan; Andreasen, Anne Sofie; Iepsen, Ulrik Winning; Plovsing, Ronni R.
In: Ugeskrift for Laeger, Vol. 183, No. 33, V11200813, 2021.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Hyperlaktatæmi
AU - Berg, Ronan Mg
AU - Jeppesen, Troels E
AU - Mohammad, Milan
AU - Andreasen, Anne Sofie
AU - Iepsen, Ulrik Winning
AU - Plovsing, Ronni R
PY - 2021
Y1 - 2021
N2 - It is a common but flawed presumption that blood lactate reflects the lactic acid production in the body's tissues. Lactate is formed directly from pyruvate and functions to dampen reductions in intracellular pH through lactate-H+ cotransport to the extracellular space. Though this may give rise to elevated blood lactate, increased lactate production is not the cause of metabolic acidosis in such instances. "Lactic acidosis" is thus an inappropriate term as it indicates causality and in this review, we suggest that in the future, the term "hyperlactataemia-associated metabolic acidosis" should be used instead.
AB - It is a common but flawed presumption that blood lactate reflects the lactic acid production in the body's tissues. Lactate is formed directly from pyruvate and functions to dampen reductions in intracellular pH through lactate-H+ cotransport to the extracellular space. Though this may give rise to elevated blood lactate, increased lactate production is not the cause of metabolic acidosis in such instances. "Lactic acidosis" is thus an inappropriate term as it indicates causality and in this review, we suggest that in the future, the term "hyperlactataemia-associated metabolic acidosis" should be used instead.
KW - Acidosis/diagnosis
KW - Acidosis, Lactic/diagnosis
KW - Humans
KW - Lactic Acid
M3 - Tidsskriftartikel
C2 - 34477100
VL - 183
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 33
M1 - V11200813
ER -
ID: 305553722