GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients

Research output: Contribution to journalJournal articleResearchpeer-review

Disproportionate growth of musculoskeletal tissue is a major cause of morbidity in both acromegalic (ACRO) and GH-deficient (GHD) patients. GH/IGF1 is likely to play an important role in the regulation of tendon and muscle collagen. We hypothesized that the local production of collagen is associated with the level of GH/IGF1.
Original languageEnglish
JournalEuropean Journal of Endocrinology
Issue number6
Pages (from-to)853-62
Number of pages10
Publication statusPublished - Dec 2010

    Research areas

  • Adult, Collagen, Collagen Type I, Collagen Type III, Human Growth Hormone, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor I, Male, Microscopy, Electron, Transmission, Middle Aged, Muscle, Skeletal, RNA, Messenger, Tendons

ID: 32321075