Characterization of cardiac repolarization in the Göttingen minipig
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Characterization of cardiac repolarization in the Göttingen minipig. / Laursen, Morten; Olesen, Søren-Peter; Grunnet, Morten; Mow, Tomas; Jespersen, Thomas; Jespersen, Thomas.
In: Journal of Pharmacological and Toxicological Methods, Vol. 63, No. 2, 2011, p. 186-95.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Characterization of cardiac repolarization in the Göttingen minipig
AU - Laursen, Morten
AU - Olesen, Søren-Peter
AU - Grunnet, Morten
AU - Mow, Tomas
AU - Jespersen, Thomas
AU - Jespersen, Thomas
N1 - Copyright © 2010 Elsevier Inc. All rights reserved.
PY - 2011
Y1 - 2011
N2 - The minipig represents an attractive experimental animal within cardiovascular research due to its extensive similarities to the human heart in terms of anatomy and physiology. Although minipigs have been used for cardiovascular research for decades no thorough characterization of the minipig cardiac electrophysiology has been performed. Therefore, we have for the first time characterized the minipig cardiac repolarization in a series of experiments ranging from mRNA quantification to in vivo studies.
AB - The minipig represents an attractive experimental animal within cardiovascular research due to its extensive similarities to the human heart in terms of anatomy and physiology. Although minipigs have been used for cardiovascular research for decades no thorough characterization of the minipig cardiac electrophysiology has been performed. Therefore, we have for the first time characterized the minipig cardiac repolarization in a series of experiments ranging from mRNA quantification to in vivo studies.
U2 - 10.1016/j.vascn.2010.10.001
DO - 10.1016/j.vascn.2010.10.001
M3 - Journal article
C2 - 20951813
VL - 63
SP - 186
EP - 195
JO - Journal of Pharmacological and Toxicological Methods
JF - Journal of Pharmacological and Toxicological Methods
SN - 1056-8719
IS - 2
ER -
ID: 33016206