Bimodal oscillations in nephron autoregulation.

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The individual functional unit of the kidney (the nephron) displays oscillations in its pressure and flow regulation at two different time scales: fast oscillations associated with a myogenic dynamics of the afferent arteriole, and slower oscillations arising from a delay in the tubuloglomerular feedback. We investigate the intra- and internephron entrainment of the two time scales. In addition to full synchronization, both wavelet analyses of experimental data and numerical simulations reveal a partial entrainment in which neighboring nephrons attain a state of chaotic synchronization with respect to their slow dynamics, but the fast dynamics remain desynchronized.
Original languageEnglish
JournalPhysical Review E (Statistical, Nonlinear, and Soft Matter Physics)
Volume66
Issue number6 Pt 1
Pages (from-to)061909
ISSN1539-3755
Publication statusPublished - 2002

ID: 8420316