Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study

Research output: Contribution to journalJournal articleResearchpeer-review

  • Martin Hinterseer
  • Thomsen, Morten Bækgaard
  • Britt-Maria Beckmann
  • Arne Pfeufer
  • Rainer Schimpf
  • H-Erich Wichmann
  • Gerhard Steinbeck
  • Marc A Vos
  • Stefan Kaab
Torsades de pointes arrhythmias (TdP) occur by definition in the setting of prolonged QT intervals. Animal models of drug induced Long-QT syndrome (dLQTS) have shown higher predictive value for proarrhythmia with beat-to-beat variability of repolarization duration (BVR) when compared with QT intervals. Here, we evaluate variability of QT intervals in patients with a history of drug-induced long QT syndrome (dLQTS) and TdP in absence of a mutation in any of the major LQTS genes.
Original languageEnglish
JournalEuropean Heart Journal
Issue number2
Pages (from-to)185-90
Number of pages6
Publication statusPublished - Jan 2008

    Research areas

  • Aged, Arrhythmias, Cardiac, Case-Control Studies, Disease Susceptibility, Electrocardiography, Female, Heart Rate, Humans, Long QT Syndrome, Male, Middle Aged, Pilot Projects, Predictive Value of Tests, Torsades de Pointes

ID: 45965394