Association between exposure to heavy occupational lifting and cardiac structure and function: a cross-sectional analysis from the Copenhagen City Heart Study
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Association between exposure to heavy occupational lifting and cardiac structure and function : a cross-sectional analysis from the Copenhagen City Heart Study. / Korshøj, Mette; Skaarup, Kristoffer Grundtvig; Lassen, Mats Christian Højbjerg; Johansen, Niklas Dyrby; Marott, Jacob Louis; Schnohr, Peter; Biering-Sørensen, Tor.
In: International Journal of Cardiovascular Imaging, Vol. 38, No. 3, 2022, p. 521-532.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Association between exposure to heavy occupational lifting and cardiac structure and function
T2 - a cross-sectional analysis from the Copenhagen City Heart Study
AU - Korshøj, Mette
AU - Skaarup, Kristoffer Grundtvig
AU - Lassen, Mats Christian Højbjerg
AU - Johansen, Niklas Dyrby
AU - Marott, Jacob Louis
AU - Schnohr, Peter
AU - Biering-Sørensen, Tor
N1 - Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer Nature B.V.
PY - 2022
Y1 - 2022
N2 - To investigate cross-sectional associations between heavy occupational lifting and cardiac structure and function. Participants from the 5th round of the Copenhagen City Heart Study, aged < 65 years old, answering a questionnaire regarding occupational physical activity, heavy occupational lifting, use of anti-hypertensive and heart medication, and data on blood pressure, cardiac structure and function, from an echocardiographic examination, were included. Adjusted linear regressions and logistic regressions were applied to estimate the cross-sectional association between heavy occupational lifting and cardiac structure and function across all included participants and in groups stratified by hypertension status, and the risk for having abnormal values of cardiac structure and function. 2511 participants were included. The cross-sectional standardized associations between heavy occupational lifting and measures of cardiac structure and function showed a trends for raised left ventricular mass index (LVMi) (β 0.14, 99% CI − 0.03 to 0.31). The standardized associations stratified by hypertensive status showed significant associations between exposure to heavy occupational lifting and LVMi (β 0.20, 99% CI − 0.002 to 0.40) and a trend of a raised end-diastolic interventricular septal thickness (IVSd) (β 0.15, 99% CI − 0.03 to 0.33) among normotensives. Exposure to heavy occupational lifting increased the odds for an abnormal IVSd (OR 1.42, 99% CI 1.07–1.89). This cross-sectional study shows heavy occupational lifting to associate with indices of abnormal cardiac structure and function among normotensives, indicating an increased risk for cardiovascular disease.
AB - To investigate cross-sectional associations between heavy occupational lifting and cardiac structure and function. Participants from the 5th round of the Copenhagen City Heart Study, aged < 65 years old, answering a questionnaire regarding occupational physical activity, heavy occupational lifting, use of anti-hypertensive and heart medication, and data on blood pressure, cardiac structure and function, from an echocardiographic examination, were included. Adjusted linear regressions and logistic regressions were applied to estimate the cross-sectional association between heavy occupational lifting and cardiac structure and function across all included participants and in groups stratified by hypertension status, and the risk for having abnormal values of cardiac structure and function. 2511 participants were included. The cross-sectional standardized associations between heavy occupational lifting and measures of cardiac structure and function showed a trends for raised left ventricular mass index (LVMi) (β 0.14, 99% CI − 0.03 to 0.31). The standardized associations stratified by hypertensive status showed significant associations between exposure to heavy occupational lifting and LVMi (β 0.20, 99% CI − 0.002 to 0.40) and a trend of a raised end-diastolic interventricular septal thickness (IVSd) (β 0.15, 99% CI − 0.03 to 0.33) among normotensives. Exposure to heavy occupational lifting increased the odds for an abnormal IVSd (OR 1.42, 99% CI 1.07–1.89). This cross-sectional study shows heavy occupational lifting to associate with indices of abnormal cardiac structure and function among normotensives, indicating an increased risk for cardiovascular disease.
KW - Blue-collar
KW - Cardiovascular disease
KW - Cohort study
KW - Heavy lifting
KW - Manual handling
KW - Occupational epidemiology
KW - Occupational physical activity
UR - http://www.scopus.com/inward/record.url?scp=85115340612&partnerID=8YFLogxK
U2 - 10.1007/s10554-021-02420-y
DO - 10.1007/s10554-021-02420-y
M3 - Journal article
C2 - 34550509
AN - SCOPUS:85115340612
VL - 38
SP - 521
EP - 532
JO - International Journal of Cardiovascular Imaging
JF - International Journal of Cardiovascular Imaging
SN - 1569-5794
IS - 3
ER -
ID: 317931418