Alpine Skiing With total knee ArthroPlasty (ASWAP): metabolism, inflammation, and skeletal muscle fiber characteristics
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Alpine Skiing With total knee ArthroPlasty (ASWAP) : metabolism, inflammation, and skeletal muscle fiber characteristics. / Kristensen, M.; Pötzelsberger, B.; Scheiber, P.; Bergdahl, A.; Hansen, C. N.; Andersen, J. L.; Narici, M.; Salvioli, S.; Conte, M.; Müller, E.; Dela, F.
In: Scandinavian Journal of Medicine & Science in Sports, Vol. 25, No. Supplement S2, 08.2015, p. 40-48.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Alpine Skiing With total knee ArthroPlasty (ASWAP)
T2 - metabolism, inflammation, and skeletal muscle fiber characteristics
AU - Kristensen, M.
AU - Pötzelsberger, B.
AU - Scheiber, P.
AU - Bergdahl, A.
AU - Hansen, C. N.
AU - Andersen, J. L.
AU - Narici, M.
AU - Salvioli, S.
AU - Conte, M.
AU - Müller, E.
AU - Dela, F.
N1 - © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
PY - 2015/8
Y1 - 2015/8
N2 - We investigated the effect of alpine skiing for 12 weeks on skeletal muscle characteristics and biomarkers of glucose homeostasis and cardiovascular risk factors. Twenty-three patients with a total knee arthroplasty (TKA) were studied 2.9 ± 0.9 years (mean ± SD) after the operation. Fourteen patients participated in the intervention group (IG) and nine in the control group (CG). Blood samples and muscle biopsies were obtained before (PRE) and 7.3 ± 0.8 days after (POST) the intervention, and blood samples again after a retention (RET) phase of 8 weeks. With skiing, glucose homeostasis improved in IG (decrease in fasting insulin, increase in muscle glycogen) but not in CG. Fiber type distribution and size, as well as capillary density and number of capillaries around the fibers (CAF), were not different between the operated and the non-operated leg in either group. The relative number of type I fibers increased with skiing in IG with no change in CG. Inflammatory biomarkers, plasma lipids, and mitochondrial proteins and activity did not change. Alpine skiing is metabolically beneficial and can be used as a training modality by elderly people with TKA.
AB - We investigated the effect of alpine skiing for 12 weeks on skeletal muscle characteristics and biomarkers of glucose homeostasis and cardiovascular risk factors. Twenty-three patients with a total knee arthroplasty (TKA) were studied 2.9 ± 0.9 years (mean ± SD) after the operation. Fourteen patients participated in the intervention group (IG) and nine in the control group (CG). Blood samples and muscle biopsies were obtained before (PRE) and 7.3 ± 0.8 days after (POST) the intervention, and blood samples again after a retention (RET) phase of 8 weeks. With skiing, glucose homeostasis improved in IG (decrease in fasting insulin, increase in muscle glycogen) but not in CG. Fiber type distribution and size, as well as capillary density and number of capillaries around the fibers (CAF), were not different between the operated and the non-operated leg in either group. The relative number of type I fibers increased with skiing in IG with no change in CG. Inflammatory biomarkers, plasma lipids, and mitochondrial proteins and activity did not change. Alpine skiing is metabolically beneficial and can be used as a training modality by elderly people with TKA.
KW - Aged
KW - Arthroplasty, Replacement, Knee
KW - Blood Glucose
KW - C-Reactive Protein
KW - Capillaries
KW - Cholesterol, HDL
KW - Cholesterol, LDL
KW - Cytokines
KW - Female
KW - Glycogen
KW - Humans
KW - Inflammation
KW - Insulin
KW - Male
KW - Middle Aged
KW - Mitochondrial Proteins
KW - Muscle Fibers, Skeletal
KW - Muscle Fibers, Slow-Twitch
KW - Muscle, Skeletal
KW - Osteoarthritis, Knee
KW - Skiing
KW - Triglycerides
U2 - 10.1111/sms.12478
DO - 10.1111/sms.12478
M3 - Journal article
C2 - 26083701
VL - 25
SP - 40
EP - 48
JO - Scandinavian Journal of Medicine & Science in Sports
JF - Scandinavian Journal of Medicine & Science in Sports
SN - 0905-7188
IS - Supplement S2
ER -
ID: 162710224