Age-dependent decline of β cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study

Research output: Contribution to journalJournal articleResearchpeer-review

  • Vincent A. Barker
  • A Lauria
  • N Schloot
  • N Hosszufalusi
  • J Ludvigsson
  • Christopher John Mathieu
  • D Mauricio
  • M Nordwall
  • B Van der Schueren
  • Mandrup-Poulsen, Thomas
  • Wa Scherbaum
  • I Weets
  • Fk Gorus
  • N Wareham
  • Rd Leslie
  • P Pozzilli
C-peptide secretion is currently the only available clinical biomarker to measure residual β-cell function in type 1 diabetes. However, the natural history of C-peptide decline after diagnosis can vary considerably dependent upon several variables. We investigated the shape of C-peptide decline over time from type 1 diabetes onset in relation to age at diagnosis, HbA1c levels and insulin dose.
Original languageEnglish
JournalDiabetes, Obesity and Metabolism Online
Volume16
Issue number3
Pages (from-to)262-267
Number of pages6
ISSN1463-1326
DOIs
Publication statusPublished - 1 Oct 2013

ID: 96513521