Søren-Peter Olesen
Professor
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3, 2200 København N.
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Regulation of cloned, Ca2+-activated K+ channels by cell volume changes.
Grunnet, Morten, MacAulay, Nanna, Jorgensen, N. K., Jensen, S., Olesen, Søren-Peter & Klærke, Dan Arne, 2002, In: Pflügers Archiv: European Journal of Physiology. 444, 1-2, p. 167-77 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome.
Grunnet, Morten, Behr, E. R., Callø, Kirstine, Hofman-Bang, J., Till, J., Christiansen, M., McKenna, W. J., Olesen, Søren-Peter & Schmitt, Nicole, 2005, In: Heart Rhythm. 2, 11, p. 1238-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apamin interacts with all subtypes of cloned small-conductance Ca2+-activated K+ channels
Grunnet, Morten, Jensen, B. S., Olesen, Søren-Peter & Klærke, Dan Arne, 2001, In: Pflügers Archiv: European Journal of Physiology. 441, p. 544-550Research output: Contribution to journal › Journal article › Research › peer-review
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Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623[N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N '-(3 '-trifluoromethylphenyl)urea]
Hansen, R. S., Diness, T. G., Christ, T., Wettwer, E., Ravens, U., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Molecular Pharmacology. 70, 4, p. 1319-1329 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of HERG potassium channels by the diphenylurea NS1643
Hansen, R. S., Diness, T. G., Christ, T., Demnitz, J., Ravens, U. & Olesen, Søren-Peter, 2006, In: Molecular Pharmacology. 69, p. 266-277Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart.
Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Journal of Pharmacology and Experimental Therapeutics. 321, 3, p. 996-1002 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).
Hansen, R. S., Diness, T. G., Christ, T., Demnitz, J., Ravens, U., Olesen, Søren-Peter & Grunnet, Morten, 2005, In: Molecular Pharmacology. 69, 1, p. 266-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo effects of the IKr agonist NS3623 on cardiac electrophysiology of the guinea pig.
Hansen, R. S., Olesen, Søren-Peter, Rønn, L. C. B. & Grunnet, Morten, 2008, In: Journal of Cardiovascular Pharmacology. 52, 1, p. 35-41 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kvalitet og styring i fremtidens universiteter - Ejerskab, ledelseskultur og de faktiske følger af universitetsloven: Forskningspolitisk årsmøde 2009
Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 2009, 78 p. Det Kongelige Danske Videnskabernes Selskab.Research output: Other contribution › Communication
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Forskning skal ikke gøre ledelsen glad
Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 11 Feb 2009, In: Universitetsavisen.Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
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Bureaukrati, Bogholderi og Bullshit
Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 30 Oct 2009, In: Weekendavisen.Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
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Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes
Hofgaard, J. P., Banach, K., Mollerup, S., Jørgensen, H. K., Olesen, Søren-Peter, von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 2008, In: Pflügers Archiv: European Journal of Physiology. 457, 2, p. 303-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CNTF inhibits high voltage activated Ca2+ currents in fetal mouse cortical neurones.
Holm, N. R., Christophersen, P., Hounsgaard, Jørn Dybkjær, Gammeltoft, S. & Olesen, Søren-Peter, 2002, In: Journal of Neurochemistry. 82, 3, p. 495-503 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modulation of the KCNQ4 potassium channel by changes in cell volume
Hougaard, C., Klærke, Dan Arne, Olesen, Søren-Peter, Hoffmann, E. K. & Jørgensen, N. K., 2004, In: Acta Physiologica (Print Edition). A45-A163, p. A64-A65Research output: Contribution to journal › Conference abstract in journal › Research
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Modulation of KCNQ4 channel activity by changes in cell volume.
Hougaard, C., Klærke, Dan Arne, Hoffmann, E. K., Olesen, Søren-Peter & Jorgensen, N. K., 2004, In: BBA General Subjects. 1660, 1-2, p. 1-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels
Jensen, B. S., Ødum, Niels, Jorgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 19, p. 10917-21 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels
Jensen, B. S., Ødum, Niels, Jørgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, p. 10917-10921Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the cloned human intermediate-conductance Ca*O2*O+-activated K*O+ channel
Jensen, B. S., Strøbæk, D., Christophersen, P., Jørgensen, T. D., Hansen, C., Silahtaroglu, Asli, Olesen, Søren-Peter & Ahring, P. K., 1998, In: The American Physiological Society. p. 848-856Research output: Contribution to journal › Journal article › Research › peer-review
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Trafficking of Kv2.1 Channels to the Axon Initial Segment by a Novel Nonconventional Secretory Pathway
Jensen, C. S., Watanabe, S., Stas, J. I., Klaphaak, J., Yamane, A., Schmitt, Nicole, Olesen, Søren-Peter, Trimmer, J. S., Rasmussen, Hanne Borger & Misonou, H., 29 Nov 2017, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 37, 48, p. 11523-11536 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specific Sorting and Post-Golgi trafficking of Dendritic Potassium Channels in Living Neurons
Jensen, C. S., Watanabe, S., Rasmussen, Hanne Borger, Schmitt, Nicole, Olesen, Søren-Peter, Frost, N. A., Blanpied, T. A. & Misonou, H., 25 Feb 2014, In: The Journal of Biological Chemistry. 289, p. 10566-10581 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inactivation as a new regulatory mechanism for neuronal Kv7 channels.
Jensen, H. S., Grunnet, Morten & Olesen, Søren-Peter, 2007, In: Biophysical Journal. 92, 8, p. 2747-56 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.
Jensen, H. S., Callø, Kirstine, Jespersen, Thomas, Jensen, B. S. & Olesen, Søren-Peter, 2005, In: Brain Research. 139, 1, p. 52-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Magnetocardiography on an isolated animal heart with a room-temperature optically pumped magnetometer
Jensen, K., Skarsfeldt, M. A., Stærkind, Hans, Arnbak, J., Balabas, M. V., Olesen, Søren-Peter, Bentzen, Bo Hjorth & Polzik, Eugene Simon, 1 Nov 2018, In: Scientific Reports. 8, 9 p., 16218.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-invasive detection of animal nerve impulses with an atomic magnetometer operating near quantum limited sensitivity
Jensen, K., Budvytyte, R., Thomas, Rodrigo A., Wang, T., Fuchs, A. M., Balabas, M. V., Vasilakis, G., Mosgaard, L. D., Stærkind, Hans, Müller, Jörg Helge, Heimburg, Thomas Rainer, Olesen, Søren-Peter & Polzik, Eugene Simon, 15 Jul 2016, In: Scientific Reports. 6, 29638.Research output: Contribution to journal › Journal article › Research › peer-review
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The Ca2+-activated K+ channel of intermediate-conductance: A molecular target for novel treatments?
Jensen Skanning, B., Strøbaek, D., Olesen, Søren-Peter & Christophersen, P., 2001, In: Current Drug Targets. 2, p. 401-422Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats
Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Greenwood, I. A. & Dalsgaard, T., May 2016, In: British Journal of Pharmacology. 173, 9, p. 1478-1490 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone
Jepps, Thomas Andrew Qvistgaard, Carr, G., Lundegaard, Pia Rengtved, Olesen, Søren-Peter & Greenwood, I. A., 15 Dec 2015, In: Journal of Physiology. 593, 24, p. 5325-40 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders
Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter & Greenwood, I. A., 2013, In: British Journal of Pharmacology. 168, 1, p. 19-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The KCNQ1 potassium channel: from gene to physiological function.
Jespersen, Thomas, Grunnet, Morten & Olesen, Søren-Peter, 2005, In: Physiology. 20, p. 408-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family.
Jespersen, Thomas, Membrez, M., Nicolas, C. S., Pitard, B., Staub, O., Olesen, Søren-Peter, Baró, I. & Abriel, H., 2007, In: Cardiovascular Research. 74, 1, p. 64-74 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?
Jespersen, Thomas, Grunnet, Morten, Rasmussen, Hanne Borger, Jørgensen, N. B., Jensen, H., Angelo, K., Olesen, Søren-Peter & Klærke, Dan Arne, 2006, In: Biochemical and Biophysical Research Communications. 341, 4, p. 979-88 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.
Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell swelling activates cloned Ca(2+)-activated K(+) channels: a role for the F-actin cytoskeleton.
Jorgensen, N. K., Pedersen, Stine Helene Falsig, Rasmussen, Hanne Borger, Grunnet, Morten, Klærke, Dan Arne & Olesen, Søren-Peter, 2003, In: BBA General Subjects. 1615, 1-2, p. 115-25 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional characterization of a cloned human intermediate-conductance Ca2+-activated K+ channel
Jørgensen, T. D., Jensen, B. S., Strøbæk, D., Christofersen, P., Olesen, Søren-Peter & Ahring, B. K., 1999, In: Annals of the New York Academy of Sciences. 868, p. 423-426Research output: Contribution to journal › Journal article › Research › peer-review
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Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia
Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart
Killeen, M. J., Thomas, G., Olesen, Søren-Peter, Demnitz, J., Stokoe, K. S., Grace, A. A. & Huang, C. L. H., 2008, In: Acta Physiologica (Print Edition). 193, 1, p. 25-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An ERG channel inhibitor from the scorpion Buthus eupeus
Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, Thomas, Olesen, Søren-Peter, Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Unique binding site on the molecular scaffold of scorpion toxin BeKm-1 provides selectivity for HERG potassium channels
Korolkova, Y. V., Bocharov, E. V., Pedersen, K. A., Maslennikov, I. V., Grinenko, O. V., Lipkin, A. V., Nosireva, E. D., Pluzhnikov, K. A., Olesen, Søren-Peter, Arseniev, A. S. & Grishin, E. V., 2002, In: Journal of Biological Chemistry. 277, p. 43104-43109Research output: Contribution to journal › Journal article › Research › peer-review
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New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
Korolkova, Y. V., Bocharov, E. V., Angelo, K., Maslennikov, I. V., Grinenko, O. V., Lipkin, A. V., Nosyreva, E. D., Pluzhnikov, K. A., Olesen, Søren-Peter, Arseniev, A. S. & Grishin, E. V., 2002, In: Journal of Biological Chemistry. 277, 45, p. 43104-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of a novel voltage-gated Na+ channel rNav 1.5a in the rat hippocampal progenitor stem cell line HiB5
Korsgaard, M., Grunnet, Morten, Christophersen, P., Ahring, P. K. & Olesen, Søren-Peter, 2001, In: Pflügers Archiv: European Journal of Physiology. 443, p. 18-30Research output: Contribution to journal › Journal article › Research › peer-review
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K(Ca)3.1 channel downregulation and impaired endothelium-derived hyperpolarization-type relaxation in pulmonary arteries from chronically hypoxic rats
Kroigaard, C., Kudryavtseva, O., Dalsgaard, T., Wandall-Frostholm, C., Olesen, Søren-Peter & Simonsen, U., Apr 2013, In: Experimental Physiology. 98, 4, p. 957-69 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels
Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Forskeren i samfundet: Forskningspolitisk årsmøde 2008
Kærgård, Niels, Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 2008, Det Kongelige Danske Videnskabernes Selskab. 42 p.Research output: Book/Report › Book › Communication
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Forsknings- og ytringsfriheden på universiteterne: forskningspolitisk årsmøde 2007
Kærgård, Niels, Bache, C., Flensted-Jensen, M., Harder, Peter, Olesen, Søren-Peter & Wewer, Ulla M., 2007, København: Det Kongelige Danske Videnskabernes Selskab.Research output: Book/Report › Book › Communication
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Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics
Larsen, A. P. & Olesen, Søren-Peter, 2010, In: P L o S One. 5, 2, p. e9021Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.
Larsen, A. P., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 6, p. 1137-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state
Larsen, A. P., Steffensen, Annette Buur, Grunnet, Morten & Olesen, Søren-Peter, 2011, In: Biophysical Journal. 101, 4, p. 818-27 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts
Laursen, M., Grunnet, Morten, Olesen, Søren-Peter, Jespersen, Thomas & Mow, T., 2012, In: Journal of Pharmacological and Toxicological Methods. 64, 2, p. 134-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of cardiac repolarization in the Göttingen minipig
Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle
Layne, J. J., Nausch, B., Olesen, Søren-Peter & Nelson, M. T., 2009, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 298, 2, p. R378-84Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13436
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Tissue-specific effects of acetylcholine in the canine heart
Research output: Contribution to journal › Journal article › Research › peer-review
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493
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Non-invasive detection of animal nerve impulses with an atomic magnetometer operating near quantum limited sensitivity
Research output: Contribution to journal › Journal article › Research › peer-review
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346
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Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
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