Nils Billestrup
Professor
- 1984
- Published
Preparation of 125I-protein A usable for up to 10 months in immunoassays
Dyrberg, T. & Billestrup, Nils, 6 Jul 1984, In: Journal of Immunological Methods. 71, 2, p. 193-201 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1985
- Published
Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells
Billestrup, Nils, 1985, In: Biomedica Biochimica Acta. 44, 1, p. 85-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone binding to specific receptors stimulates growth and function of cloned insulin-producing rat insulinoma RIN-5AH cells
Billestrup, Nils & Martin, J. M., Mar 1985, In: Endocrinology. 116, 3, p. 1175-81 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1986
- Published
Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro
Billestrup, Nils, Swanson, L. W. & Vale, W., Sep 1986, In: Proceedings of the National Academy of Sciences of the United States of America. 83, 18, p. 6854-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of corticotropin-releasing factor (CRF) target cells and effects of dexamethasone on binding in anterior pituitary using a fluorescent analog of CRF
Schwartz, J., Billestrup, Nils, Perrin, M., Rivier, J. & Vale, W., Nov 1986, In: Endocrinology. 119, 5, p. 2376-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1987
- Published
Growth hormone-releasing factor induces c-fos expression in cultured primary pituitary cells
Billestrup, Nils, Mitchell, R. L., Vale, W. & Verma, I. M., Apr 1987, In: Molecular endocrinology (Baltimore, Md.). 1, 4, p. 300-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of a pituitary corticotropin-releasing factor binding protein by chemical cross-linking
Nishimura, E., Billestrup, Nils, Perrin, M. & Vale, W., 25 Sep 1987, In: The Journal of Biological Chemistry. 262, 27, p. 12893-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1989
- Published
Growth hormone is a growth factor for the differentiated pancreatic beta-cell
Linde, S., Welinder, B. S., Billestrup, Nils, Madsen, O. D. & Nielsen, Jens Høiriis, Jan 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 1, p. 165-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple growth hormone-binding proteins are expressed on insulin-producing cells
Møldrup, A., Billestrup, Nils, Thorn, N. A., Lernmark, A. & Nielsen, Jens Høiriis, Aug 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 8, p. 1173-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adenohypophysial changes in mice transgenic for human growth hormone-releasing factor: a histological, immunocytochemical, and electron microscopic investigation
Stefaneanu, L., Kovacs, K., Horvath, E., Asa, S. L., Losinski, N. E., Billestrup, Nils, Price, J. & Vale, W., Nov 1989, In: Endocrinology. 125, 5, p. 2710-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
- Published
Effect of growth hormone and serum on the expression of the proto-oncogenes c-jun and c-fos in insulin producing cells
Petersen, E. D., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1171-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the growth hormone receptor gene in insulin producing cells
Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1151-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of somatotroph growth and growth hormone biosynthesis by activin in vitro
Billestrup, Nils, González-Manchón, C., Potter, E. & Vale, W., Feb 1990, In: Molecular endocrinology (Baltimore, Md.). 4, 2, p. 356-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pituitary mammosomatotroph adenomas develop in old mice transgenic for growth hormone-releasing hormone
Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, Nils, Gonzalez-Manchon, C. & Vale, W., Mar 1990, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 193, 3, p. 232-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rat insulinoma cells express both a 115-kDa growth hormone receptor and a 95-kDa prolactin receptor structurally related to the hepatic receptors
Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 25 May 1990, In: The Journal of Biological Chemistry. 265, 15, p. 8686-90 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introduction of exogenous growth hormone receptors augments growth hormone-responsive insulin biosynthesis in rat insulinoma cells
Billestrup, Nils, Møldrup, A., Serup, Palle, Mathews, L. S., Norstedt, G. & Nielsen, Jens Høiriis, Sep 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 18, p. 7210-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
The stimulatory effect of growth hormone, prolactin, and placental lactogen on beta-cell proliferation is not mediated by insulin-like growth factor-I
Billestrup, Nils & Nielsen, Jens Høiriis, Aug 1991, In: Endocrinology. 129, 2, p. 883-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone action in rat insulinoma cells expressing truncated growth hormone receptors
Møldrup, A., Allevato, G., Dyrberg, T., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1991, In: The Journal of Biological Chemistry. 266, 26, p. 17441-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
The role of growth hormone and prolactin in beta cell growth and regeneration
Nielsen, Jens Høiriis, Møldrup, A., Billestrup, Nils, Petersen, E. D., Allevato, G. & Stahl, M., 1992, Pancreatic islet cell regeneration and growth. Vol. 321. p. 9-17; discussion 19-20 (Advances in Experimental Medicine and Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase
Wang, X., Uhler, M. D., Billestrup, Nils, Norstedt, G., Talamantes, F., Nielsen, Jens Høiriis & Carter-Su, C., 25 Aug 1992, In: The Journal of Biological Chemistry. 267, 24, p. 17390-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pituitary adenomas in mice transgenic for growth hormone-releasing hormone
Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, Nils, Gonzalez-Manchon, C. & Vale, W., Nov 1992, In: Endocrinology. 131, 5, p. 2083-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Growth of the endocrine pancreas: the role of somatolactogenic hormones and receptors
Billestrup, Nils, Møldrup, A., Allevato, G., Petersen, Erik Brinch, Pedersen, Johan, Hansen, J. A. & Nielsen, Jens Høiriis, Feb 1993, In: Biochemical Society Transactions. 21, 1, p. 146-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Cell transfection as a tool to study growth hormone action
Norstedt, G., Enberg, B., Francis, S., Hansson, A., Hulthén, A., Lobie, P. E., Sliva, D., Wood, T. J. & Billestrup, Nils, Jul 1994, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 206, 3, p. 181-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of intracellular domains in the growth hormone receptor involved in signal transduction
Billestrup, Nils, Allevato, G., Norstedt, G., Møldrup, A. & Nielsen, Jens Høiriis, Jul 1994, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 206, 3, p. 205-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase
VanderKuur, J. A., Wang, X., Zhang, L., Campbell, G. S., Allevato, G., Billestrup, Nils, Norstedt, G. & Carter-Su, C., 26 Aug 1994, In: The Journal of Biological Chemistry. 269, 34, p. 21709-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cellular mechanism of growth hormone signal transduction
Lobie, P. E., Wood, T. J., Sliva, D., Billestrup, Nils, Waters, M. J., Enberg, B. & Norstedt, G., Dec 1994, In: Acta Paediatrica. Supplement. 406, p. 39-46; discussion 47Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription
Billestrup, Nils, Bouchelouche, P., Allevato, G., Ilondo, M. & Nielsen, Jens Høiriis, 28 Mar 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 7, p. 2725-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2
VanderKuur, J., Allevato, G., Billestrup, Nils, Norstedt, G. & Carter-Su, C., 31 Mar 1995, In: The Journal of Biological Chemistry. 270, 13, p. 7587-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1
Argetsinger, L. S., Hsu, G. W., Myers, M. G., Billestrup, Nils, White, M. F. & Carter-Su, C., 16 Jun 1995, In: The Journal of Biological Chemistry. 270, 24, p. 14685-92 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation
Allevato, G., Billestrup, Nils, Goujon, L., Galsgaard, E. D., Norstedt, G., Postel-Vinay, M. C., Kelly, P. A. & Nielsen, Jens Høiriis, 21 Jul 1995, In: The Journal of Biological Chemistry. 270, 29, p. 17210-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular dissection of the growth hormone receptor. Identification of distinct cytoplasmic domains corresponding to different signaling pathways
Billestrup, Nils, Allevato, G., Møldrup, A., Galsgaard, E. D., Amstrup, J., Hansen, J. A., Svensson, C. & Nielsen, Jens Høiriis, 7 Sep 1995, In: Annals of the New York Academy of Sciences. 766, p. 481-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor
VanderKuur, J. A., Wang, X., Zhang, L., Allevato, G., Billestrup, Nils & Carter-Su, C., 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21738-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function
Lobie, P. E., Allevato, G., Norstedt, G., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21745-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH
Smit, L. S., Meyer, D. J., Billestrup, Nils, Norstedt, G., Schwartz, J. & Carter-Su, C., May 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 5, p. 519-33 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation
Hansen, L. H., Wang, X., Kopchick, J. J., Bouchelouche, P., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, 24 May 1996, In: The Journal of Biological Chemistry. 271, 21, p. 12669-73 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene
Galsgaard, E. D., Gouilleux, F., Groner, B., Serup, Palle, Billestrup, Nils & Nielsen, Jens Høiriis, Jun 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 6, p. 652-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct cytoplasmic domains of the growth hormone receptor are required for glucocorticoid- and phorbol ester-induced decreases in growth hormone (GH) binding. These domains are different from that reported for GH-induced receptor internalization
King, A. P., Tseng, M. J., Logsdon, C. D., Billestrup, Nils & Carter-Su, C., 26 Jul 1996, In: The Journal of Biological Chemistry. 271, 30, p. 18088-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling
Argetsinger, L. S., Norstedt, G., Billestrup, Nils, White, M. F. & Carter-Su, C., 15 Nov 1996, In: The Journal of Biological Chemistry. 271, 46, p. 29415-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
The role of GH receptor tyrosine phosphorylation in Stat5 activation
Hansen, J. A., Hansen, Lars Hestbjerg, Wang, X., Kopchick, J. J., Gouilleux, F., Groner, B., Møldrup, A., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, Jun 1997, In: Journal of Molecular Endocrinology. 18, 3, p. 213-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas
Carlsson, C., Tornehave, D., Lindberg, K., Galante, P., Billestrup, Nils, Michelsen, B., Larsson, L. I. & Nielsen, Jens Høiriis, Sep 1997, In: Endocrinology. 138, 9, p. 3940-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling
Adams, T. E., Hansen, J. A., Starr, R., Nicola, N. A., Hilton, D. J. & Billestrup, Nils, 16 Jan 1998, In: The Journal of Biological Chemistry. 273, 3, p. 1285-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanism of growth hormone signalling
Billestrup, Nils, Hansen, J. A., Hansen, L. H., Møldrup, A., Galsgaard, E. D. & Nielsen, Jens Høiriis, Apr 1998, In: Endocrine Journal. 45 Suppl, p. S41-5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of glucose transport and c-fos and egr-1 expression in cells with mutated or endogenous growth hormone receptors
Gong, T. W., Meyer, D. J., Liao, J., Hodge, C. L., Campbell, G. S., Wang, X., Billestrup, Nils, Carter-Su, C. & Schwartz, J., Apr 1998, In: Endocrinology. 139, 4, p. 1863-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the inhibitory effect of growth hormone on primary preadipocyte differentiation
Hansen, L. H., Madsen, B., Teisner, B., Nielsen, Jens Høiriis & Billestrup, Nils, Aug 1998, In: Molecular endocrinology (Baltimore, Md.). 12, 8, p. 1140-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Beta cell proliferation and growth factors
Nielsen, Jens Høiriis, Svensson, C., Møldrup, A., Galsgaard, E. D. & Billestrup, Nils, Jan 1999, In: Journal of Molecular Medicine. 77, 1, p. 62-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developmental expression of proprotein convertase 1/3 in the rat
Lee, Y. C., Damholt, A. B., Billestrup, Nils, Kisbye, T., Galante, P., Michelsen, B., Kofod, H. & Nielsen, Jens Høiriis, 10 Sep 1999, In: Molecular and Cellular Endocrinology. 155, 1-2, p. 27-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins
Hansen, J. A., Lindberg, K., Hilton, D. J., Nielsen, Jens Høiriis & Billestrup, Nils, Nov 1999, In: Molecular endocrinology (Baltimore, Md.). 13, 11, p. 1832-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Growth hormone (GH)-independent dimerization of GH receptor by a leucine zipper results in constitutive activation
Behncken, S. N., Billestrup, Nils, Brown, R., Amstrup, J., Conway-Campbell, B. & Waters, M. J., 2 Jun 2000, In: The Journal of Biological Chemistry. 275, 22, p. 17000-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B
Stofega, M. R., Herrington, J., Billestrup, Nils & Carter-Su, C., Sep 2000, In: Molecular endocrinology (Baltimore, Md.). 14, 9, p. 1338-50 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
The effect of suppressor of cytokine signaling 3 on GH signaling in beta-cells
Rønn, S. G., Hansen, J. A., Lindberg, K., Karlsen, A. E. & Billestrup, Nils, Sep 2002, In: Molecular endocrinology (Baltimore, Md.). 16, 9, p. 2124-34 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 15311848
Most downloads
-
210
downloads
JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
38
downloads
Butyrate protects pancreatic beta cells from cytokine-induced dysfunction
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
32
downloads
Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published