Michael Jonathan Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin
Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael Jonathan & Witting, P. K., 15 Sep 2008, In: Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 28 Aug 2007, In: Biochemistry. 46, 34, p. 9853-64 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells
Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In: Free Radical Biology and Medicine. 134, p. 526-536Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid
Lloyd, M. M., van Reyk, D. M., Davies, Michael Jonathan & Hawkins, Clare Louise, 1 Sep 2008, In: Biochemical Journal. 414, 2, p. 271-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance
Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 15 Aug 2009, In: Biochemical Journal. 422, 1, p. 111-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of protein cross-links induced by oxidative reactions
Hägglund, Per Mårten, Mariotti, M. & Davies, Michael Jonathan, 2018, In: Expert Review of Proteomics. 15, 8, p. 665-681Research output: Contribution to journal › Review › Research › peer-review
- Published
Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications
Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In: Redox Biology. 24, UNSP 101226.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines
Summers, F. A., Morgan, P. E., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2008, In: Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]
Flouda, K., Davies, Michael Jonathan & Hawkins, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides
Hampton, M. B., Morgan, P. E. & Davies, Michael Jonathan, 11 Sep 2002, In: FEBS Letters. 527, 1-3, p. 289-92 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products
Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Jul 2002, In: Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function
Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates
Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Mar 2012, In: Free Radical Biology & Medicine. 52, 6, p. 1075-85 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus
Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Increasing capacity to deliver diabetes self-management education: Results of the DESMOND lay educator non-randomized controlled equivalence trial
Carey, M. E., Mandalia, P. K., Daly, H., Gray, L. J., Hale, R., Martin Stacey, L., Taub, N., Skinner, Timothy, Stone, M., Heller, S., Khunti, K. & Davies, Michael Jonathan, 1 Jan 2014, In: Diabetic Medicine. 31, 11, p. 1431-1438 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of DNA damage by oxidised amino acids and proteins
Luxford, C., Dean, R. T. & Davies, Michael Jonathan, 2002, In: Biogerontology. 3, 1-2, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of O-2 on riboflavin-mediated photo-oxidation of lysozyme: [Meeting Abstract]
Silva, E., Tirapegui, C., Fuentes-Lemus, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Caroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S58-S59 P-46.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone
Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael Jonathan, 2020, In: Redox Biology. 28, 9 p., 101335 .Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides
Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael Jonathan, 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack
Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, Apr 2002, In: European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis
Moheimani, F., Kim, C. H. J., Rahmanto, A. S., van Reyk, D. M. & Davies, Michael Jonathan, Jul 2012, In: Atherosclerosis. 223, 1, p. 144-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides
Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2014, In: Free Radical Biology & Medicine. 70, p. 96-105 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides
Rees, M. D., Bottle, S. E., Fairfull-Smith, K. E., Malle, E., Whitelock, J. M. & Davies, Michael Jonathan, 1 Jul 2009, In: Biochemical Journal. 421, 1, p. 79-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products
Gracanin, M. & Davies, Michael Jonathan, 15 May 2007, In: Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction kinetics of selenium -containing compounds with oxidants
Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael Jonathan, 2020, In: Free Radical Biology and Medicine. 155, p. 58-68Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins: [Meeting Abstract]
Ignasiak-Kciuk, M., Shashikadze, B., Frackowiak, K., Gamon, Luke Francis, Davies, Michael Jonathan & Marciniak, B., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S30-S30 89.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]
Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael Jonathan, 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase
Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael Jonathan, 2020, In: Redox Biology. 28, 12 p., 101331.Research output: Contribution to journal › Journal article › Research › peer-review
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Truscott, R. J. W., Mizdrak, J., Friedrich, M. G., Hooi, M. Y., Lyons, B., Jamie, J. F., Davies, Michael Jonathan, Wilmarth, P. A. & David, L. L., Jun 2012, In: Experimental Eye Research. 99, p. 48-54 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Key role of cysteine residues and sulfenic acids in thermal- and H2O2-mediated modification of β-lactoglobulin
Krämer, A. C., Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael Jonathan, 2016, In: Free Radical Biology & Medicine. 97, 8, p. 544–555 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Key role of cysteine residues in thermal- and H2O2-mediated modification of beta-lactoglobulin
Krämer, A. C., Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael Jonathan, 2016, In: Free Radical Biology & Medicine. 96, Suppl. 1, p. S16 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress
Pattison, D. I. & Davies, Michael Jonathan, 27 Apr 2004, In: Biochemistry. 43, 16, p. 4799-809 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation
Pattison, D. I. & Davies, Michael Jonathan, 17 May 2005, In: Biochemistry. 44, 19, p. 7378-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols
Sauerland, M., Mertes, R., Morozzi, C., Eggler, A. L., Gamon, Luke Francis & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 169, p. 1-11 569.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics and biological consequences of quinone-induced protein adduction: [Meeting Abstract]
Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2018, In: Free Radical Biology and Medicine. 120, S1, p. S55-S55 P-34.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants
Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, Dec 2007, In: Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance
Storkey, C., Pattison, D. I., Ignasiak, M. T., Schiesser, C. H. & Davies, Michael Jonathan, Dec 2015, In: Free Radical Biology & Medicine. 89, p. 1049-1056 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage
Moreau, S., Davies, Michael Jonathan, Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In: The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid oxidation in human low-density lipoprotein induced by metmyoglobin/H2O2: involvement of alpha-tocopheroxyl and phosphatidylcholine alkoxyl radicals
Witting, P. K., Willhite, C. A., Davies, Michael Jonathan & Stocker, R., Dec 1999, In: Chemical Research in Toxicology. 12, 12, p. 1173-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation
Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, Michael Jonathan, Beattie, J. H. & Galley, H. F., 2015, In: British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
M. jannaschii FtsZ, a key protein in bacterial cell division, is inactivated by peroxyl radical-mediated methionine oxidation
Reyes, J. S., Fuentes Lemus, Eduardo, Aspée, A., Davies, Michael Jonathan, Monasterio, O. & López-Alarcón, C., 2021, In: Free Radical Biology and Medicine. 166, p. 53-66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MODULATION OF ENDOTHELIAL CELL FUNCTION BY THE MYELOPEROXIDASE-DERIVED OXIDANT HYPOCHLOROUS ACID (HOCl) AND ITS CONTRIBUTION TO ATHEROSCLEROSIS
Rayner, B. S., Lloyd, M. M., Summers, F. A., Davies, Michael Jonathan & Hawkins, Clare Louise, 2014, In: Hypertension.Research output: Contribution to journal › Journal article › Research › peer-review
Mammalian heme peroxidases: from molecular mechanisms to health implications
Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In: Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.Research output: Contribution to journal › Journal article › Research › peer-review
Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion
Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael Jonathan, Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In: Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products
Headlam, H. A. & Davies, Michael Jonathan, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation
Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 2018, In: Journal of Proteome Research. 17, 6, p. 2017-2027Research output: Contribution to journal › Journal article › Research › peer-review
Mechanisms and consequences of oxidative damage to extracellular matrix
Kennett, E. C., Chuang, Christine, Degendorfer, G., Whitelock, J. M. & Davies, Michael Jonathan, Oct 2011, In: Biochemical Society Transactions. 39, 5, p. 1279-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mechanisms of degradation of the natural high-potency sweetener (2R,4R)-monatin in mock beverage solutions
Storkey, C., Pattison, D. I., Gaspard, D. S., Hagestuen, E. D. & Davies, Michael Jonathan, 16 Apr 2014, In: Journal of Agricultural and Food Chemistry. 62, 15, p. 3476-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanistic view of iodide in oxidative stress: [Meeting Abstract]
Kciuk, M. I., Davies, Michael Jonathan & Marciniak, B., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S122-S122 P-254.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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