Michael Jonathan Davies
Michael Jonathan Davies

Professor


  1. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues

    Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael Jonathan, Jul 2002, In : Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Singlet oxygen-mediated damage to proteins and its consequences

    Davies, Michael Jonathan, 6 Jun 2003, In : Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In : Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In : Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides

    Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In : Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

    Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 395-405 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Selenium-containing amino acids as direct and indirect antioxidants

    Rahmanto, A. S. & Davies, Michael Jonathan, Nov 2012, In : I U B M B Life. 64, 11, p. 863-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage

    Skaff, O., Pattison, D. I., Morgan, P. E., Bachana, R., Jain, V. K., Priyadarsini, K. I. & Davies, Michael Jonathan, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 305-16 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins

    Hazell, L. J., Davies, Michael Jonathan & Stocker, R., 1999, In : Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: A cross-sectional study

    Gray, L. J., Tringham, J. R., Davies, Michael Jonathan, Webb, D. R., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Dec 2010, In : Vascular Health and Risk Management. 6, 1, p. 837-842 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study

    Khunti, K., Taub, N., Tringham, J., Jarvis, J., Farooqi, A., Skinner, Timothy & Davies, Michael Jonathan, 1 Apr 2010, In : Primary Care Diabetes. 4, 1, p. 25-32 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima

    Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan & Smith, N. C., Jun 2003, In : Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]

    Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

    Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : P L o S One. 11, 12, 16 p., e0168844.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function

    Indo, H. P., Hawkins, Clare Louise, Nakanishi, I., Matsumoto, K., Matsui, H., Suenaga, S., Davies, Michael Jonathan, St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Vol. 240. p. 439-456 18 p. (Handbook of Experimental Pharmacology, Vol. 240).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode

    Silva, E., Barrias, P., Fuentes-Lemus, E., Tirapegui, C., Aspee, A., Carroll, L., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 131, p. 133-143

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses

    Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., Aug 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides

    Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 241-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3

    Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, Michael Jonathan & Winterbourn, C. C., 1 Dec 2010, In : Biochemical Journal. 432, 2, p. 313-21 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1

    Kovacevic, Z., Sahni, S., Lok, K. H., Davies, Michael Jonathan, Wink, D. A. & Richardson, D. R., May 2017, In : B B A - Reviews on Cancer. 1861, 5 Pt A, p. 995-999 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach

    Storkey, C., Davies, Michael Jonathan & Pattison, D. I., Aug 2014, In : Free Radical Biology & Medicine. 73, p. 60-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Reduced metal ion concentrations in atherosclerotic plaques from subjects with type 2 diabetes mellitus

    Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., Croft, K. D., Mori, T. A., Vacata, V., Daemen, M. J. A. P., Waltenberger, J. & Davies, Michael Jonathan, Jun 2012, In : Atherosclerosis. 222, 2, p. 512-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage

    Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, Jul 2015, In : Free Radical Biology & Medicine. 84, p. 279-288 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability

    Karimi, M., Ignasiak, M. T., Chan, B., Croft, A. K., Radom, L., Schiesser, C. H., Pattison, D. I. & Davies, Michael Jonathan, 12 Dec 2016, In : Scientific Reports. 6, 12 p., 38572.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Reactive species formed on proteins exposed to singlet oxygen

    Davies, Michael Jonathan, Jan 2004, In : Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

    Pattison, D. I., Davies, Michael Jonathan & Hawkins, Clare Louise, Aug 2012, In : Free Radical Research. 46, 8, p. 975-95 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Reaction of quinones with proteins: Kinetics of adduct formation, effects on enzymatic activity and protein structure, and potential reversibility of modifications

    Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 137, p. 169-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation

    Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In : Biochemical Journal. 365, Pt 3, p. 605-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants

    Carroll, L., Davies, Michael Jonathan & Pattison, D. I., 2015, In : Free Radical Research. 49, 6, p. 750-767 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species

    Moreau, S., Davies, Michael Jonathan & Puppo, A., 16 Aug 1995, In : Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Reaction between protein radicals and other biomolecules

    Østdal, H., Davies, Michael Jonathan & Andersen, H. J., 15 Jul 2002, In : Free Radical Biology & Medicine. 33, 2, p. 201-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, Jul 2000, In : Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Radical chemistry of epigallocatechin gallate and its relevance to protein damage

    Hagerman, A. E., Dean, R. T. & Davies, Michael Jonathan, 1 Jun 2003, In : Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Quinone-induced protein modifications: kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins

    Li, Y., Jongberg, S., Andersen, Mogens Larsen, Davies, Michael Jonathan & Lund, Marianne N., 2016, In : Free Radical Biology & Medicine. 97, p. 148-157 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline

    Morgan, P. E., Pattison, D. I. & Davies, Michael Jonathan, 15 Jan 2012, In : Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching

    David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Redox Biology. 24, UNSP 101207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Protein-bound kynurenine is a photosensitizer of oxidative damage

    Parker, N. R., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., 1 Nov 2004, In : Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Protein oxidation injury occurs during pediatric cardiopulmonary bypass

    Sheil, M. L., Luxford, C., Davies, Michael Jonathan, Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In : Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Protein oxidation and peroxidation

    Davies, Michael Jonathan, 2016, In : Biochemical Journal. 473, 7, p. 805-825 21 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Protein oxidation and ageing

    Linton, S., Davies, Michael Jonathan & Dean, R. T., Sep 2001, In : Experimental Gerontology. 36, 9, p. 1503-18 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin

    Silvester, J. A., Timmins, G. S. & Davies, Michael Jonathan, 15 Feb 1998, In : Archives of Biochemistry and Biophysics. 350, 2, p. 249-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification

    Forman, H. J., Davies, Michael Jonathan, Krämer, Anna Carola, Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In : Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage

    Davies, Michael Jonathan, 1 Dec 1996, In : Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Protein and low molecular mass thiols as targets and inhibitors of glycation reactions

    Zeng, J. & Davies, Michael Jonathan, Dec 2006, In : Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Feb 2004, In : Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Preventing protein oxidation with sugars: scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives

    Storkey, C., Pattison, D. I., White, J. M., Schiesser, C. H. & Davies, Michael Jonathan, 19 Nov 2012, In : Chemical Research in Toxicology. 25, 11, p. 2589-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Photodynamically generated bovine serum albumin radicals: evidence for damage transfer and oxidation at cysteine and tryptophan residues

    Silvester, J. A., Timmins, G. S. & Davies, Michael Jonathan, 15 Mar 1998, In : Free Radical Biology & Medicine. 24, 5, p. 754-66 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Photo-oxidation-induced inactivation of the selenium-containing protective enzymes thioredoxin reductase and glutathione peroxidase

    Suryo Rahmanto, A., Pattison, D. I. & Davies, Michael Jonathan, 15 Sep 2012, In : Free Radical Biology & Medicine. 53, 6, p. 1308-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Photo-oxidation of proteins and its role in cataractogenesis

    Davies, Michael Jonathan & Truscott, R. J., 2001, In : Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205