Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2005
  2. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In : Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers

    Birinyi-Strachan, L. C., Davies, Michael Jonathan, Lewis, R. J. & Nicholson, G. M., Oct 2005, In : Neuropharmacology. 49, 5, p. 669-86 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Protein oxidation injury occurs during pediatric cardiopulmonary bypass

    Sheil, M. L., Luxford, C., Davies, Michael Jonathan, Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In : Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins

    Zeng, J. & Davies, Michael Jonathan, Aug 2005, In : Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Jul 2005, In : Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Guanine-specific DNA damage induced by gamma-irradiated histone

    Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael Jonathan & Kawanishi, S., 15 Jun 2005, In : Biochemical Journal. 388, Pt 3, p. 813-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation

    Pattison, D. I. & Davies, Michael Jonathan, 17 May 2005, In : Biochemistry. 44, 19, p. 7378-87 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells

    Brown, B. E., Dean, R. T. & Davies, Michael Jonathan, Feb 2005, In : Diabetologia. 48, 2, p. 361-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. The oxidative environment and protein damage

    Davies, Michael Jonathan, 17 Jan 2005, In : B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2004
  12. Protein-bound kynurenine is a photosensitizer of oxidative damage

    Parker, N. R., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., 1 Nov 2004, In : Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides

    Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 241-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress

    Pattison, D. I. & Davies, Michael Jonathan, 27 Apr 2004, In : Biochemistry. 43, 16, p. 4799-809 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Feb 2004, In : Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Reactive species formed on proteins exposed to singlet oxygen

    Davies, Michael Jonathan, Jan 2004, In : Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper

    Stadler, N., Lindner, R. A. & Davies, Michael Jonathan, 2004, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    EPR spin trapping of protein radicals

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products

    Headlam, H. A. & Davies, Michael Jonathan, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2003
  22. Published

    Hypochlorite-induced oxidation of amino acids, peptides and proteins

    Hawkins, C. L., Pattison, D. I. & Davies, Michael Jonathan, Dec 2003, In : Amino Acids. 25, 3-4, p. 259-74 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Fragmentation of extracellular matrix by hypochlorous acid

    Woods, A. A. & Davies, Michael Jonathan, 15 Nov 2003, In : Biochemical Journal. 376, Pt 1, p. 219-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 12 Nov 2003, In : Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles

    Knott, H. M., Brown, B. E., Davies, Michael Jonathan & Dean, R. T., Sep 2003, In : European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Singlet oxygen-mediated damage to proteins and its consequences

    Davies, Michael Jonathan, 6 Jun 2003, In : Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Radical chemistry of epigallocatechin gallate and its relevance to protein damage

    Hagerman, A. E., Dean, R. T. & Davies, Michael Jonathan, 1 Jun 2003, In : Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima

    Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan & Smith, N. C., Jun 2003, In : Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, Apr 2003, In : Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Photo-oxidation of cells generates long-lived intracellular protein peroxides

    Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Mar 2003, In : Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques

    Woods, A. A., Linton, S. M. & Davies, Michael Jonathan, 1 Mar 2003, In : Biochemical Journal. 370, Pt 2, p. 729-35 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals

    Headlam, H. A. & Davies, Michael Jonathan, 1 Jan 2003, In : Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The retina: oxidative stress and diabetes

    van Reyk, D. M., Gillies, M. C. & Davies, Michael Jonathan, 2003, In : Redox Report (Online). 8, 4, p. 187-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2002
  35. Published

    Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides

    Hampton, M. B., Morgan, P. E. & Davies, Michael Jonathan, 11 Sep 2002, In : FEBS letters. 527, 1-3, p. 289-92 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s

    Pattison, D. I., Dean, R. T. & Davies, Michael Jonathan, 1 Aug 2002, In : Toxicology. 177, 1, p. 23-37 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation

    Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In : Biochemical Journal. 365, Pt 3, p. 605-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Jul 2002, In : Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Reaction between protein radicals and other biomolecules

    Østdal, H., Davies, Michael Jonathan & Andersen, H. J., 15 Jul 2002, In : Free Radical Biology & Medicine. 33, 2, p. 201-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues

    Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael Jonathan, Jul 2002, In : Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones

    Headlam, H. A. & Davies, Michael Jonathan, 1 Jun 2002, In : Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein

    Knott, H. M., Baoutina, A., Davies, Michael Jonathan & Dean, R. T., 15 Apr 2002, In : Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, Apr 2002, In : European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In : FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals

    Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In : Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Analysis of aliphatic amino acid alcohols in oxidized proteins

    Morin, B., Fu, S., Wang, H., Davies, Michael Jonathan & Dean, R. T., 2002, In : Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Induction of DNA damage by oxidised amino acids and proteins

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, 2002, In : Biogerontology. 3, 1-2, p. 95-102 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 2001
  49. Published

    Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis

    Hawkins, C. L., Brown, B. E. & Davies, Michael Jonathan, 15 Nov 2001, In : Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Protein oxidation and ageing

    Linton, S., Davies, Michael Jonathan & Dean, R. T., Sep 2001, In : Experimental Gerontology. 36, 9, p. 1503-18 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals

    Hawkins, C. L. & Davies, Michael Jonathan, Aug 2001, In : Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Generation and propagation of radical reactions on proteins

    Hawkins, C. L. & Davies, Michael Jonathan, 2 Apr 2001, In : B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    An investigation of the chromium oxidation state of a monoanionic chromium tris(catecholate) complex by X-ray absorption and EPR spectroscopies

    Pattison, D. I., Levina, A., Davies, Michael Jonathan & Lay, P. A., 15 Jan 2001, In : Inorganic Chemistry. 40, 2, p. 214-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds

    Pattison, D. I. & Davies, Michael Jonathan, 2001, In : Chemical Research in Toxicology. 14, 10, p. 1453-64 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity

    Pattison, D. I., Davies, Michael Jonathan, Levina, A., Dixon, N. E. & Lay, P. A., 2001, In : Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205