Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2008
  2. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Oxidative damage to extracellular matrix and its role in human pathologies

    Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jun 2008, In : Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation

    Stadler, N., Stanley, N., Heeneman, S., Vacata, V., Daemen, M. J. A. P., Bannon, P. G., Waltenberger, J. & Davies, Michael Jonathan, May 2008, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 1024-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage

    Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael Jonathan, 15 Mar 2008, In : Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial

    Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In : BMJ. 336, 7642, p. 491-495 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The DESMOND educational intervention

    Davies, Michael Jonathan, Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In : Chronic Illness. 4, 1, p. 38-40 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links

    Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2008, In : Biochemical Journal. 410, 3, p. 565-574 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2007
  10. Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants

    Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, Dec 2007, In : Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In : Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides

    Dremina, E. S., Sharov, V. S., Davies, Michael Jonathan & Schöneich, C., Oct 2007, In : Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 28 Aug 2007, In : Biochemistry. 46, 34, p. 9853-64 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses

    Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., Aug 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A randomized controlled trial examining combinations of repaglinide, metformin and NPH insulin

    Davies, Michael Jonathan, Thaware, P. K., Tringham, J. R., Howe, J., Jarvis, J., Johnston, V., Kitchener, D. L., Skinner, Timothy, McNally, P. G. & Lawrence, I. G., 1 Jul 2007, In : Diabetic Medicine. 24, 7, p. 714-719 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products

    Gracanin, M. & Davies, Michael Jonathan, 15 May 2007, In : Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism

    Kennett, E. C. & Davies, Michael Jonathan, 15 Apr 2007, In : Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro

    Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, 6 Mar 2007, In : FEBS letters. 581, 5, p. 1067-70 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages

    Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, Mar 2007, In : F E B S Journal. 274, 6, p. 1530-41 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Degradation of extracellular matrix and its components by hypobromous acid

    Rees, M. D., McNiven, T. N. & Davies, Michael Jonathan, 15 Jan 2007, In : Biochemical Journal. 401, 2, p. 587-96 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2006
  22. Published

    Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study

    Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In : Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Protein and low molecular mass thiols as targets and inhibitors of glycation reactions

    Zeng, J. & Davies, Michael Jonathan, Dec 2006, In : Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

    Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael Jonathan, 1 Sep 2006, In : Biochemical Journal. 398, 2, p. 197-206 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals

    Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael Jonathan & Radom, L., 31 Aug 2006, In : Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael Jonathan, 4 Jul 2006, In : Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions

    Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael Jonathan, 1 May 2006, In : Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides

    Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael Jonathan, 1 May 2006, In : Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid

    Malle, E., Marsche, G., Arnhold, J. & Davies, Michael Jonathan, Apr 2006, In : B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives

    Rees, M. D. & Davies, Michael Jonathan, 8 Mar 2006, In : Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides

    Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In : Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Actions of ultraviolet light on cellular structures

    Pattison, D. I. & Davies, Michael Jonathan, 2006, In : E X S. 96, p. 131-57 27 p.

    Research output: Contribution to journalJournal articleResearch

  33. 2005
  34. Published

    Diabetes screening anxiety and beliefs

    Skinner, Timothy, Davies, Michael Jonathan, Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In : Diabetic Medicine. 22, 11, p. 1497-1502 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In : Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation

    Rees, M. D., Pattison, D. I. & Davies, Michael Jonathan, 1 Oct 2005, In : Biochemical Journal. 391, Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation

    Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In : Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In : Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers

    Birinyi-Strachan, L. C., Davies, Michael Jonathan, Lewis, R. J. & Nicholson, G. M., Oct 2005, In : Neuropharmacology. 49, 5, p. 669-86 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Protein oxidation injury occurs during pediatric cardiopulmonary bypass

    Sheil, M. L., Luxford, C., Davies, Michael Jonathan, Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In : Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins

    Zeng, J. & Davies, Michael Jonathan, Aug 2005, In : Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Jul 2005, In : Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Guanine-specific DNA damage induced by gamma-irradiated histone

    Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael Jonathan & Kawanishi, S., 15 Jun 2005, In : Biochemical Journal. 388, Pt 3, p. 813-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation

    Pattison, D. I. & Davies, Michael Jonathan, 17 May 2005, In : Biochemistry. 44, 19, p. 7378-87 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells

    Brown, B. E., Dean, R. T. & Davies, Michael Jonathan, Feb 2005, In : Diabetologia. 48, 2, p. 361-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. The oxidative environment and protein damage

    Davies, Michael Jonathan, 17 Jan 2005, In : B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2004
  48. Protein-bound kynurenine is a photosensitizer of oxidative damage

    Parker, N. R., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., 1 Nov 2004, In : Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides

    Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 241-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress

    Pattison, D. I. & Davies, Michael Jonathan, 27 Apr 2004, In : Biochemistry. 43, 16, p. 4799-809 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Feb 2004, In : Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Reactive species formed on proteins exposed to singlet oxygen

    Davies, Michael Jonathan, Jan 2004, In : Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper

    Stadler, N., Lindner, R. A. & Davies, Michael Jonathan, 2004, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    EPR spin trapping of protein radicals

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205