Michael Jonathan Davies

Michael Jonathan Davies

Professor

ORCID: 0000-0002-5196-6919

Publication year:
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  1. 2021
  2. Published

    Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues

    Flouda, Konstantina, Gammelgaard, Bente, Davies, Michael Jonathan & Hawkins, Clare Louise, May 2021, In : Redox Biology. 41, 101873.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Oxidation of protein disulfide bonds by singlet oxygen gives rise to glutathionylated proteins

    Jiang, S., Carroll, L., Rasmussen, L. M. & Davies, Michael Jonathan, Jan 2021, In : Redox Biology. 38, 101822.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Dynein regulates Kv7.4 channel trafficking from the cell membrane

    van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael Jonathan, Greenwood, Iain Andrew, Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In : Journal of General Physiology. 153, 3, 19 p., e202012760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases

    Davies, Michael Jonathan, 2021, In : Pharmacology and Therapeutics. 218, 23 p., 107685.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage

    Flouda, Konstantina, Mercer, J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2021, In : Free Radical Biology & Medicine. 166, p. 165-177

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2020
  8. Published

    Oxidant-induced glutathionylation at protein disulfide bonds

    Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 20 Nov 2020, In : Free Radical Biology and Medicine. 160, p. 513-525 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization

    Gamon, Luke Francis, Guo, Chaorui, He, Jianfei, Hägglund, Per Mårten, Hawkins, Clare Louise & Davies, Michael Jonathan, Sep 2020, In : Redox Biology. 36, 9 p., 101586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

    Guo, Chaorui, Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In : Redox Biology. 36, 14 p., 101666.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

    Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael Jonathan, Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In : Archives of Biochemistry and Biophysics. 689, 7 p., 108443.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway

    Shu, N., Hägglund, Per Mårten, Cai, H., Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2020, In : Redox Biology. 29, UNSP 101400.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Azocompounds as generators of defined radical species: Contributions and challenges for free radical research

    López-Alarcón, C., Fuentes-Lemus, E., Figueroa, J. D., Dorta, E., Schöneich, C. & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 160, p. 78-91

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

    Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In : Scientific Reports. 13 p., 666.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols

    Karimi, M., Crossett, B., Cordwell, S. J., Pattison, David & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 154, p. 62-74 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis

    Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael Jonathan & Siebuhr, A. S., 2020, In : Scientific Reports. 10, 1, 10 p., 17300.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings

    Zacharias, T., Flouda, Konstantina, Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael Jonathan, 2020, In : Biochemical Pharmacology. 173, 14 p., 113631.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion

    Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In : RSC Advances. 10, 43, p. 25786-25800 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure

    Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael Jonathan & Lund, Marianne N., 2020, In : Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone

    Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael Jonathan, 2020, In : Redox Biology. 28, 9 p., 101335 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Interaction kinetics of selenium -containing compounds with oxidants

    Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 155, p. 58-68

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase

    Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael Jonathan, 2020, In : Redox Biology. 28, 12 p., 101331.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages

    Guo, Chaorui, Sileikaite, Inga, Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants. 9, 12, 14 p., 1255.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN−)

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In : Redox Biology. 36, 13 p., 101641.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin

    He, Jianfei, fjp320, fjp320, Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael Jonathan & Hägglund, Per Mårten, 2020, In : Redox Biology. 36, 11 p., 101631.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks

    Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2020, In : Free Radical Biology and Medicine. 152, p. 61-73

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination

    Möllers Blossom, Benedikt, Russo, D. A., Singh, Raushan Kumar, Van Oort, B., Keller, Malene Billeskov, Simonsen, Tor Ivan, Perzon, A., Gamon, Luke Francis, Davies, Michael Jonathan, Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In : ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants & Redox Signaling. 32, 13, p. 957-981

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites

    Leinisch, F., Mariotti, M., Andersen, Sofie Hagel, Lindemose, S., Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael Jonathan, 2020, In : Scientific Reports. 10, 1, 11 p., 3106.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation

    Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In : Free Radical Biology and Medicine. 153, p. 12-16 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2019
  32. Published

    Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]

    Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.

    Research output: Contribution to journal › Conference abstract in journal › Research

  33. Published

    Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]

    Shu, N., Hägglund, Per Mårten & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S9-S9 8.

    Research output: Contribution to journal › Conference abstract in journal › Research

  34. Published

    Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function: [Meeting Abstract]

    Shu, N. & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S49-S49 168.

    Research output: Contribution to journal › Conference abstract in journal › Research

  35. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule

    Davies, Michael Jonathan & Schiesser, C. H., 2019, In : New Journal of Chemistry. 43, 25, p. 9759-9765

    Research output: Contribution to journal › Review › Research › peer-review

  36. Published

    3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism

    Avila, F., Ravello, N., Zanocco, A. L., Gamon, Luke Francis, Davies, Michael Jonathan & Silva, E., 2019, In : Free Radical Biology and Medicine. 141, p. 103-114

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]

    Gamon, Luke Francis & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.

    Research output: Contribution to journal › Conference abstract in journal › Research

  38. Published

    Analysis of protein chlorination by mass spectrometry

    Nybo, T., Davies, Michael Jonathan & Rogowska-Wrzesinska, A., 2019, In : Redox Biology. 26, 10 p., UNSP 101236.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan

    Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 143, p. 375-386

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines

    Carroll, L., Karton, A., Radom, L., Davies, Michael Jonathan & Pattison, D. I., 2019, In : Chemical Research in Toxicology. 32, 3, p. 513-525 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula

    Chen, Z., Leinisch, F., Greco, Ines, Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 68-81

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

    Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 20, p. 496-513

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action

    Tiwari, M. K., Hägglund, Per Mårten, Møller, I. M., Davies, Michael Jonathan & Bjerrum, Morten Jannik, 2019, In : Redox Biology. 26, 15 p., 101262.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Detection, identification, and quantification of oxidative protein modifications

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Journal of Biological Chemistry. 294, 51, p. 19683-19708

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin

    Krämer, Anna Carola & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models

    Chen, Z., Kondrashina, A., Greco, Ines, Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}

    Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael Jonathan & Siebuhr, A. S., 2019, In : Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.

    Research output: Contribution to journal › Conference abstract in journal › Research

  48. Published

    Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells

    Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 134, p. 526-536

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

    Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 24, UNSP 101226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]

    Flouda, Konstantina, Davies, Michael Jonathan & Hawkins, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.

    Research output: Contribution to journal › Conference abstract in journal › Research

  51. Published

    Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins: [Meeting Abstract]

    Ignasiak-Kciuk, M., Shashikadze, B., Frackowiak, K., Gamon, Luke Francis, Davies, Michael Jonathan & Marciniak, B., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S30-S30 89.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  52. Published

    Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 136, p. 118-134

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]

    Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.

    Research output: Contribution to journal › Conference abstract in journal › Research

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