Michael Jonathan Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3, 2200 København N, 12.6, Building: 30
- 2021
- Published
Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues
Flouda, Konstantina, Gammelgaard, Bente, Davies, Michael Jonathan & Hawkins, Clare Louise, May 2021, In : Redox Biology. 41, 101873.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidation of protein disulfide bonds by singlet oxygen gives rise to glutathionylated proteins
Jiang, S., Carroll, L., Rasmussen, L. M. & Davies, Michael Jonathan, Jan 2021, In : Redox Biology. 38, 101822.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
Davies, Michael Jonathan, 2021, In : Pharmacology and Therapeutics. 218, 23 p., 107685.Research output: Contribution to journal › Review › Research › peer-review
- 2020
- Published
Oxidant-induced glutathionylation at protein disulfide bonds
Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 20 Nov 2020, In : Free Radical Biology and Medicine. 160, p. 513-525 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization
Gamon, Luke Francis, Guo, Chaorui, He, Jianfei, Hägglund, Per Mårten, Hawkins, Clare Louise & Davies, Michael Jonathan, Sep 2020, In : Redox Biology. 36, 9 p., 101586.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
Guo, Chaorui, Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In : Redox Biology. 36, 14 p., 101666.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes
Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael Jonathan, Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In : Archives of Biochemistry and Biophysics. 689, 7 p., 108443.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway
Shu, N., Hägglund, Per Mårten, Cai, H., Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2020, In : Redox Biology. 29, UNSP 101400.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Azocompounds as generators of defined radical species: Contributions and challenges for free radical research
López-Alarcón, C., Fuentes-Lemus, E., Figueroa, J. D., Dorta, E., Schöneich, C. & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 160, p. 78-91Research output: Contribution to journal › Review › Research › peer-review
- Published
Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In : Scientific Reports. 13 p., 666.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols
Karimi, M., Crossett, B., Cordwell, S. J., Pattison, David & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 154, p. 62-74 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis
Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael Jonathan & Siebuhr, A. S., 2020, In : Scientific Reports. 10, 1, 10 p., 17300.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings
Zacharias, T., Flouda, Konstantina, Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael Jonathan, 2020, In : Biochemical Pharmacology. 173, 14 p., 113631.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion
Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In : RSC Advances. 10, 43, p. 25786-25800 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure
Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael Jonathan & Lund, Marianne N., 2020, In : Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone
Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael Jonathan, 2020, In : Redox Biology. 28, 9 p., 101335 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction kinetics of selenium -containing compounds with oxidants
Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 155, p. 58-68Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase
Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael Jonathan, 2020, In : Redox Biology. 28, 12 p., 101331.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages
Guo, Chaorui, Sileikaite, Inga, Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants. 9, 12, 14 p., 1255.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN−)
Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In : Redox Biology. 36, 13 p., 101641.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin
He, Jianfei, fjp320, fjp320, Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael Jonathan & Hägglund, Per Mårten, 2020, In : Redox Biology. 36, 11 p., 101631.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks
Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2020, In : Free Radical Biology and Medicine. 152, p. 61-73Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination
Möllers Blossom, Benedikt, Russo, D. A., Singh, Raushan Kumar, Van Oort, B., Keller, Malene Billeskov, Simonsen, Tor Ivan, Perzon, A., Gamon, Luke Francis, Davies, Michael Jonathan, Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In : ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease
Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants & Redox Signaling. 32, 13, p. 957-981Research output: Contribution to journal › Review › Research › peer-review
- Published
UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites
Leinisch, F., Mariotti, M., Andersen, Sofie Hagel, Lindemose, S., Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael Jonathan, 2020, In : Scientific Reports. 10, 1, 11 p., 3106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation
Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In : Free Radical Biology and Medicine. 153, p. 12-16 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]
Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]
Shu, N., Hägglund, Per Mårten & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S9-S9 8.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function: [Meeting Abstract]
Shu, N. & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S49-S49 168.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule
Davies, Michael Jonathan & Schiesser, C. H., 2019, In : New Journal of Chemistry. 43, 25, p. 9759-9765Research output: Contribution to journal › Review › Research › peer-review
- Published
3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism
Avila, F., Ravello, N., Zanocco, A. L., Gamon, Luke Francis, Davies, Michael Jonathan & Silva, E., 2019, In : Free Radical Biology and Medicine. 141, p. 103-114Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]
Gamon, Luke Francis & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Analysis of protein chlorination by mass spectrometry
Nybo, T., Davies, Michael Jonathan & Rogowska-Wrzesinska, A., 2019, In : Redox Biology. 26, 10 p., UNSP 101236.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan
Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 143, p. 375-386Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines
Carroll, L., Karton, A., Radom, L., Davies, Michael Jonathan & Pattison, D. I., 2019, In : Chemical Research in Toxicology. 32, 3, p. 513-525 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula
Chen, Z., Leinisch, F., Greco, Ines, Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 68-81Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase
Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 20, p. 496-513Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action
Tiwari, M. K., Hägglund, Per Mårten, Møller, I. M., Davies, Michael Jonathan & Bjerrum, Morten Jannik, 2019, In : Redox Biology. 26, 15 p., 101262.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection, identification, and quantification of oxidative protein modifications
Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Journal of Biological Chemistry. 294, 51, p. 19683-19708Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin
Krämer, Anna Carola & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models
Chen, Z., Kondrashina, A., Greco, Ines, Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}
Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael Jonathan & Siebuhr, A. S., 2019, In : Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells
Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 134, p. 526-536Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications
Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 24, UNSP 101226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]
Flouda, Konstantina, Davies, Michael Jonathan & Hawkins, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins: [Meeting Abstract]
Ignasiak-Kciuk, M., Shashikadze, B., Frackowiak, K., Gamon, Luke Francis, Davies, Michael Jonathan & Marciniak, B., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S30-S30 89.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function
Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 136, p. 118-134Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]
Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)
Tur, J. A., Jacob, C., Chaimbault, P., Tadayyon, M., Richling, E., Hermans, N., dos Santos, C. N., Diederich, M., Giblin, L., Elhabiri, M., Gaucher, C., Andreoletti, P., Fernandes, A., Davies, Michael Jonathan, Bartoszek, A. & Cherkaoui-Malki, M., 2019, In : Free Radical Research. 53, S1, p. 1163-1170Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching
David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Redox Biology. 24, 9 p., 101207.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Research output: Contribution to journal › Journal article › Research › peer-review
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