Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2021
  2. Published

    Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues

    Flouda, Konstantina, Gammelgaard, Bente, Davies, Michael Jonathan & Hawkins, Clare Louise, May 2021, In: Redox Biology. 41, 101873.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Anthocyanin complex niosome gel accelerates oral wound healing: In vitro and clinical studies

    Damrongrungruang, T., Paphangkorakit, J., Limsitthichaikoon, S., Khampaenjiraroch, B., Davies, Michael Jonathan, Sungthong, B. & Priprem, A., 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 37, 14 p., 102423.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions

    Mariotti, M., Rogowska-Wrzesinska, A., Hägglund, P. & Davies, Michael Jonathan, 2021, In: Journal of Biological Chemistry. 296, 100360.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Crosslinking of human plasma C-reactive protein to human serum albumin via disulfide bond oxidation

    Jiang, S., Hagglund, P., Carroll, L., Rasmussen, L. M. & Davies, Michael Jonathan, 2021, In: Redox Biology. 41, 17 p., 101925.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Dynein regulates Kv7.4 channel trafficking from the cell membrane

    van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, P., Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael Jonathan, Greenwood, Iain Andrew, Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation

    Jiang, S., Carroll, L., Mariotti, M., Hagglund, P. & Davies, Michael Jonathan, 2021, In: Redox Biology. 41, 16 p., 101874.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage

    Fuentes Lemus, Eduardo, Jiang, S., Hägglund, P. & Davies, Michael Jonathan, 2021, In: Food Hydrocolloids. 121, 16 p., 107060.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols

    Sauerland, M., Mertes, R., Morozzi, C., Eggler, A. L., Gamon, L. F. & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 169, p. 1-11 569.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    M. jannaschii FtsZ, a key protein in bacterial cell division, is inactivated by peroxyl radical-mediated methionine oxidation

    Reyes, J. S., Fuentes Lemus, Eduardo, Aspée, A., Davies, Michael Jonathan, Monasterio, O. & López-Alarcón, C., 2021, In: Free Radical Biology and Medicine. 166, p. 53-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases

    Davies, Michael Jonathan, 2021, In: Pharmacology and Therapeutics. 218, 23 p., 107685.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats

    Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael Jonathan, 2021, In: Scientific Reports. 11, 1, 18 p., 12712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Oxidation of lysozyme induced by peroxyl radicals involves amino acid modifications, loss of activity, and formation of specific crosslinks

    Fuentes Lemus, Eduardo, Mariotti, M., Hagglund, P., Leinisch, F., Fierro, A., Silva, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2021, In: Free Radical Biology and Medicine. 167, p. 258-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Oxidation of protein disulfide bonds by singlet oxygen gives rise to glutathionylated proteins

    Jiang, S., Carroll, L., Rasmussen, L. M. & Davies, Michael Jonathan, 2021, In: Redox Biology. 38, 16 p., 101822.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Processed foods drive intestinal barrier permeability and microvascular diseases

    Snelson, M., Tan, S. M., Clarke, R. E., De Pasquale, C., Thallas-Bonke, V., Nguyen, T. V., Penfold, S. A., Harcourt, B. E., Sourris, K. C., Lindblom, R. S., Ziemann, M., Steer, D., El-Osta, A., Davies, Michael Jonathan, Donnellan, L., Deo, P., Kellow, N. J., Cooper, M. E., Woodruff, T. M., Mackay, C. R., Forbes, J. M. & Coughlan, M. T., 2021, In: Science Advances. 7, 14, eabe4841.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 172, p. 633-651

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage

    Flouda, Konstantina, Mercer, J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2021, In: Free Radical Biology & Medicine. 166, p. 165-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Suppressive effect of 1,4-anhydro-4-seleno-D-talitol (SeTal) on atopic dermatitis-like skin lesions in mice through regulation of inflammatory mediators

    Voss, G. T., de Oliveira, R. L., Davies, Michael Jonathan, Domingues, W. B., Campos, V. F., Soares, M. P., Luchese, C., Schiesser, C. H. & Wilhelm, E. A., 2021, In: Journal of Trace Elements in Medicine and Biology. 67, 10 p., 126795.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2020
  20. Published

    Oxidant-induced glutathionylation at protein disulfide bonds

    Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 20 Nov 2020, In: Free Radical Biology and Medicine. 160, p. 513-525 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization

    Gamon, L. F., Guo, C., He, J., Hägglund, P., Hawkins, Clare Louise & Davies, Michael Jonathan, Sep 2020, In: Redox Biology. 36, 9 p., 101586.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

    Guo, C., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In: Redox Biology. 36, 14 p., 101666.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

    Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, L., Paumann-Page, M., Hofbauer, S., Davies, Michael Jonathan, Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In: Archives of Biochemistry and Biophysics. 689, 7 p., 108443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway

    Shu, N., Hagglund, P., Cai, H., Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2020, In: Redox Biology. 29, UNSP 101400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Azocompounds as generators of defined radical species: Contributions and challenges for free radical research

    López-Alarcón, C., Fuentes-Lemus, E., Figueroa, J. D., Dorta, E., Schöneich, C. & Davies, Michael Jonathan, 2020, In: Free Radical Biology and Medicine. 160, p. 78-91

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

    Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In: Scientific Reports. 13 p., 666.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols

    Karimi, M., Crossett, B., Cordwell, S. J., Pattison, David & Davies, Michael Jonathan, 2020, In: Free Radical Biology and Medicine. 154, p. 62-74 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis

    Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael Jonathan & Siebuhr, A. S., 2020, In: Scientific Reports. 10, 1, 10 p., 17300.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings

    Zacharias, T., Flouda, Konstantina, Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael Jonathan, 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction

    Gentile, C., Kesteven, S., Wu, J., Davies, Michael Jonathan, Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion

    Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure

    Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael Jonathan & Lund, Marianne N., 2020, In: Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone

    Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael Jonathan, 2020, In: Redox Biology. 28, 9 p., 101335 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Interaction kinetics of selenium -containing compounds with oxidants

    Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael Jonathan, 2020, In: Free Radical Biology and Medicine. 155, p. 58-68

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase

    Gamon, L. F., Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael Jonathan, 2020, In: Redox Biology. 28, 12 p., 101331.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages

    Guo, C., Sileikaite, Inga, Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In: Antioxidants. 9, 12, 14 p., 1255.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN)

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In: Redox Biology. 36, 13 p., 101641.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin

    He, J., Becares, E. R., Thulstrup, Peter Waaben, Gamon, L. F., Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael Jonathan & Hägglund, P., 2020, In: Redox Biology. 36, 11 p., 101631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks

    Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hagglund, P., Silva, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2020, In: Free Radical Biology and Medicine. 152, p. 61-73

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination

    Blossom, B. M., Russo, D. A., Singh, R. K., Van Oort, B., Keller, M. B., Simonsen, Tor Ivan, Perzon, A., Gamon, L. F., Davies, Michael Jonathan, Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In: ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In: Antioxidants & Redox Signaling. 32, 13, p. 957-981

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites

    Leinisch, F., Mariotti, M., Andersen, Sofie Hagel, Lindemose, S., Hägglund, P., Møllegaard, Niels Erik & Davies, Michael Jonathan, 2020, In: Scientific Reports. 10, 1, 11 p., 3106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation

    Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In: Free Radical Biology and Medicine. 153, p. 12-16 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2019
  45. Published

    Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]

    Gamon, L. F., Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael Jonathan, 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.

    Research output: Contribution to journalConference abstract in journalResearch

  46. Published

    Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]

    Shu, N., Hagglund, P. M. & Davies, Michael Jonathan, 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S9-S9 8.

    Research output: Contribution to journalConference abstract in journalResearch

  47. Published

    Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function: [Meeting Abstract]

    Shu, N. & Davies, Michael Jonathan, 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S49-S49 168.

    Research output: Contribution to journalConference abstract in journalResearch

  48. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule

    Davies, Michael Jonathan & Schiesser, C. H., 2019, In: New Journal of Chemistry. 43, 25, p. 9759-9765

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism

    Avila, F., Ravello, N., Zanocco, A. L., Gamon, L. F., Davies, Michael Jonathan & Silva, E., 2019, In: Free Radical Biology and Medicine. 141, p. 103-114

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]

    Gamon, L. F. & Davies, Michael Jonathan, 2019, In: Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.

    Research output: Contribution to journalConference abstract in journalResearch

  51. Published

    Analysis of protein chlorination by mass spectrometry

    Nybo, T., Davies, Michael Jonathan & Rogowska-Wrzesinska, A., 2019, In: Redox Biology. 26, 10 p., UNSP 101236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan

    Fuentes-Lemus, E., Mariotti, M., Hagglund, P., Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael Jonathan, 2019, In: Free Radical Biology and Medicine. 143, p. 375-386

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines

    Carroll, L., Karton, A., Radom, L., Davies, Michael Jonathan & Pattison, D. I., 2019, In: Chemical Research in Toxicology. 32, 3, p. 513-525 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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