Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. Published

    Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]

    Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  2. Published

    Photo-oxidation of lysozyme triggered by riboflavin is O2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter-molecular crosslinks

    Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael Jonathan & López-Alarcón, C., 20 May 2020, In : Free Radical Biology and Medicine. 152, p. 61-73 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan

    Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 143, p. 375-386

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent

    Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael Jonathan & Lopez-Alarcon, C., 1 Aug 2018, In : Food Chemistry. 256, p. 119-128

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals

    Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2016, In : RSC Advances. 6, 63, p. 57948-57955 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

    Fu, S., Davies, Michael Jonathan, Stocker, R. & Dean, R. T., 1 Aug 1998, In : Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification

    Forman, H. J., Davies, Michael Jonathan, Krämer, Anna Carola, Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In : Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]

    Flouda, Konstantina, Davies, Michael Jonathan & Hawkins, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.

    Research output: Contribution to journalConference abstract in journalResearch

  9. Published

    Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion

    Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In : RSC Advances. 10, 43, p. 25786-25800 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function

    Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael Jonathan & López-Alarcón, C., Nov 2017, In : Free Radical Biology and Medicine. 112, p. 60-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]

    Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.

    Research output: Contribution to journalConference abstract in journalResearch

  12. A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis

    Dunn, L. L., Simpson, P. J. L., Prosser, H. C., Lecce, L., Yuen, G. S. C., Buckle, A., Sieveking, D. P., Vanags, L. Z., Lim, P. R., Chow, R. W. Y., Lam, Y. T., Clayton, Z., Bao, S., Davies, Michael Jonathan, Stadler, N., Celermajer, D. S., Stocker, R., Bursill, C. A., Cooke, J. P. & Ng, M. K. C., Feb 2014, In : Diabetes. 63, 2, p. 675-87 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides

    Dremina, E. S., Sharov, V. S., Davies, Michael Jonathan & Schöneich, C., Oct 2007, In : Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Peroxynitrite-mediated oxidation of plasma fibronectin

    Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael Jonathan, Aug 2016, In : Free Radical Biology & Medicine. 97, p. 602-615 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin

    Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael Jonathan, Dec 2015, In : Free Radical Biology & Medicine. 89, p. 721-733 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]

    Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  17. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function

    Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael Jonathan, 1 Feb 2018, In : Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Biochemistry and pathology of radical-mediated protein oxidation

    Dean, R. T., Fu, S., Stocker, R. & Davies, Michael Jonathan, 1997, In : Biochemical Journal. 324 ( Pt 1), p. 1-18 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Stable markers of oxidant damage to proteins and their application in the study of human disease

    Davies, Michael Jonathan, Fu, S., Wang, H. & Dean, R. T., Dec 1999, In : Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Protein oxidation and peroxidation

    Davies, Michael Jonathan, 2016, In : Biochemical Journal. 473, 7, p. 805-825 21 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Sulfur and selenium in oxidation protection

    Davies, Michael Jonathan, 2015, In : La chimica e l’industria, Chimica & Materiali. 2015, 6, p. 50-54

    Research output: Contribution to journalReviewResearchpeer-review

  22. Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention

    Davies, Michael Jonathan, Jan 2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 8-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Photo-oxidation of proteins and its role in cataractogenesis

    Davies, Michael Jonathan & Truscott, R. J., 2001, In : Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Reactive species formed on proteins exposed to singlet oxygen

    Davies, Michael Jonathan, Jan 2004, In : Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants & Redox Signaling. 32, 13, p. 957-981

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage

    Davies, Michael Jonathan, 1 Dec 1996, In : Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods

    Davies, Michael Jonathan, 2016, In : Methods. 109, p. 21-30 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. The oxidative environment and protein damage

    Davies, Michael Jonathan, 17 Jan 2005, In : B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    EPR spin trapping of protein radicals

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates

    Davies, Michael Jonathan & Hawkins, C. L., Dec 2000, In : Free Radical Research. 33, 6, p. 719-29 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Singlet oxygen-mediated damage to proteins and its consequences

    Davies, Michael Jonathan, 6 Jun 2003, In : Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Free Radical Research origins

    Davies, Michael Jonathan, Jan 2012, In : Free Radical Research. 46, 1, p. 1

    Research output: Contribution to journalJournal articleResearch

  34. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule

    Davies, Michael Jonathan & Schiesser, C. H., 2019, In : New Journal of Chemistry. 43, 25, p. 9759-9765

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Tempus fugit horizontal ellipsis

    Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 1-1

    Research output: Contribution to journalEditorialResearchpeer-review

  36. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial

    Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In : BMJ. 336, 7642, p. 491-495 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The DESMOND educational intervention

    Davies, Michael Jonathan, Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In : Chronic Illness. 4, 1, p. 38-40 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  38. Published

    Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching

    David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Redox Biology. 24, 9 p., 101207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation

    Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael Jonathan, 27 Jul 2011, In : Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study

    Crasto, W., Jarvis, J., Khunti, K., Skinner, Timothy, Gray, L. J., Brela, J., Troughton, J., Daly, H., Lawrence, I. G., McNally, P. G., Carey, M. E. & Davies, Michael Jonathan, 1 Sep 2011, In : Diabetes Research and Clinical Practice. 93, 3, p. 328-336 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A hydrogen-donating monohydroxamate scavenges ferryl myoglobin radicals

    Cooper, C. E., Green, E. S., Rice-Evans, C. A., Davies, Michael Jonathan & Wrigglesworth, J. M., Apr 1994, In : Free Radical Research. 20, 4, p. 219-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues

    Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael Jonathan, 1 Jan 2016, In : Free Radical Biology & Medicine. 90, p. 195-205 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells

    Cook, N. L., Viola, H. M., Sharov, V. S., Hool, L. C., Schöneich, C. & Davies, Michael Jonathan, 1 Mar 2012, In : Free Radical Biology & Medicine. 52, 5, p. 951-61 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins

    Cook, N. L., Pattison, D. I. & Davies, Michael Jonathan, 1 Dec 2012, In : Free Radical Biology & Medicine. 53, 11, p. 2072-80 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias

    Collis, C. S., Rice-Evans, C. & Davies, Michael Jonathan, Apr 1996, In : International Journal of Biochemistry & Cell Biology. 28, 4, p. 405-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells

    Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael Jonathan, 15 Apr 2014, In : Biochemical Journal. 459, 2, p. 313-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Oxidation and modification of extracellular matrix and its role in disease

    Chuang, Christine, Degendorfer, G. & Davies, Michael Jonathan, Sep 2014, In : Free Radical Research. 48, 9, p. 970-89 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models

    Chen, Z., Kondrashina, A., Greco, Ines, Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula

    Chen, Z., Leinisch, F., Greco, Ines, Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 68-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula: [Meeting Abstract]

    Chen, Z., Leinisch, F., Greco, Ines, Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, Supplement 1, p. S47 1 p., P-8.

    Research output: Contribution to journalConference abstract in journalResearch

ID: 38036205