Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. Published

    Protein oxidation and ageing

    Linton, S., Davies, Michael Jonathan & Dean, R. T., Sep 2001, In: Experimental Gerontology. 36, 9, p. 1503-18 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells

    Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael Jonathan & Hawkins, Clare Louise, Dec 2013, In: Free Radical Biology & Medicine. 65, p. 1352-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

    Lloyd, M. M., van Reyk, D. M., Davies, Michael Jonathan & Hawkins, Clare Louise, 1 Sep 2008, In: Biochemical Journal. 414, 2, p. 271-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

    Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael Jonathan, Iozzo, R. V. & Whitelock, J. M., Apr 2014, In: Matrix Biology. 35, p. 112-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Nitration alters laminin polymerization: [Meeting Abstract]

    Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2018, In: Free Radical Biology and Medicine. 120, S1, p. S127-S127 P-271.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  6. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

    Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In: Redox Biology. 24, UNSP 101226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages

    Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In: Free Radical Biology & Medicine. 94, p. 88-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

    Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, Seyed Mojtaba, De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael Jonathan, Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, Jul 2000, In: Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA

    Luxford, C., Morin, B., Dean, R. T. & Davies, Michael Jonathan, 15 Nov 1999, In: Biochemical Journal. 344 Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Induction of DNA damage by oxidised amino acids and proteins

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, 2002, In: Biogerontology. 3, 1-2, p. 95-102 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Azocompounds as generators of defined radical species: Contributions and challenges for free radical research

    López-Alarcón, C., Fuentes-Lemus, E., Figueroa, J. D., Dorta, E., Schöneich, C. & Davies, Michael Jonathan, 2020, In: Free Radical Biology and Medicine. 160, p. 78-91

    Research output: Contribution to journalReviewResearchpeer-review

  13. Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

    Mai, K., Smith, N. C., Feng, Z., Katrib, M., Slapeta, J., Slapetova, I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan, Zhang, X., Norton, R. S. & Belli, S. I., Sep 2011, In: International Journal for Parasitology (Online). 41, 11, p. 1157-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Chasing Great Paths of Helmut “Oxidative Stress” Sies

    Majima, H., Indo, H., Nakanishi, I., Suenaga, S., Matsumoto, K., Matsui, H., Minamiyami, Y., Ichikawa, H., Yen, H., Hawkins, C., Davies, Michael Jonathan, Ozawa, T. & St. Clair, D., 2016, In: Archives of Biochemistry and Biophysics. 595, p. 54-60 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid

    Malle, E., Marsche, G., Arnhold, J. & Davies, Michael Jonathan, Apr 2006, In: B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

    Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 2018, In: Journal of Proteome Research. 17, 6, p. 2017-2027

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions

    Mariotti, M., Rogowska-Wrzesinska, A., Hägglund, Per Mårten & Davies, Michael Jonathan, 2021, In: Journal of Biological Chemistry. 296, 100360.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Absence of synproportionation between oxy and ferryl leghemoglobin. off

    Mathieu, C., Swaraj, K., Davies, Michael Jonathan, Trinchant, J. C. & Puppo, A., Aug 1997, In: Free Radical Research. 27, 2, p. 165-71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes

    Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael Jonathan, 1998, In: Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation

    Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, Michael Jonathan, Beattie, J. H. & Galley, H. F., 2015, In: British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage

    Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael Jonathan, 15 Mar 2008, In: Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis

    Moheimani, F., Morgan, P. E., van Reyk, D. M. & Davies, Michael Jonathan, Jun 2010, In: B B A - Reviews on Cancer. 1802, 6, p. 561-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins

    Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael Jonathan, 2011, In: Journal of Diabetes Research. 2011, p. 851280

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis

    Moheimani, F., Kim, C. H. J., Rahmanto, A. S., van Reyk, D. M. & Davies, Michael Jonathan, Jul 2012, In: Atherosclerosis. 223, 1, p. 144-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species

    Moreau, S., Davies, Michael Jonathan & Puppo, A., 16 Aug 1995, In: Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage

    Moreau, S., Davies, Michael Jonathan, Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In: The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase

    Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael Jonathan, 27 Mar 2015, In: Free Radical Research. 49, 6, p. 743-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Feb 2009, In: Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Jul 2002, In: Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes

    Morgan, P. E., Sheahan, P. J., Pattison, D. I. & Davies, Michael Jonathan, Aug 2013, In: Free Radical Biology & Medicine. 61, p. 229-42 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, Apr 2002, In: European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Feb 2004, In: Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline

    Morgan, P. E., Pattison, D. I. & Davies, Michael Jonathan, 15 Jan 2012, In: Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In: Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal

    Morgan, P. E., Sheahan, P. J. & Davies, Michael Jonathan, 2014, In: PloS one. 9, 1, 11 p., e86564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In: Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

    Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage

    Morin, B., Davies, Michael Jonathan & Dean, R. T., 15 Mar 1998, In: Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation

    Morin, B., Bubb, W. A., Davies, Michael Jonathan, Dean, R. T. & Fu, S., Nov 1998, In: Chemical Research in Toxicology. 11, 11, p. 1265-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Analysis of aliphatic amino acid alcohols in oxidized proteins

    Morin, B., Fu, S., Wang, H., Davies, Michael Jonathan & Dean, R. T., 2002, In: Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Synthesis and cellular evaluation of click-chemistry probes to study the biological effects of alpha, beta-unsaturated carbonyls

    Morozzi, C., Sauerland, M., Gamon, Luke Francis, Manandhar, Asmita, Ulven, Trond & Davies, Michael Jonathan, 2022, In: Redox Biology. 52, 8 p., 102299.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte

    Murphy, P. G., Davies, Michael Jonathan, Columb, M. O. & Stratford, N., Apr 1996, In: British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction

    Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael Jonathan, Oct 2014, In: Free Radical Research. 48, 10, p. 1256-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress

    Ng, H. H., Leo, C. H., O'Sullivan, K., Alexander, S., Davies, Michael Jonathan, Schiesser, C. H. & Parry, L. J., Mar 2017, In: Biochemical Pharmacology. 128, p. 34-45 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin

    Nielsen, L. R., Lund, Marianne N., Davies, Michael Jonathan, Nielsen, J. H. & Nielsen, S. B., 2018, In: International Dairy Journal. 79, p. 52-61 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I

    Nobécourt, E., Tabet, F., Lambert, G., Puranik, R., Bao, S., Yan, L., Davies, Michael Jonathan, Brown, B. E., Jenkins, A. J., Dusting, G. J., Bonnet, D. J., Curtiss, L. K., Barter, P. J. & Rye, K., Apr 2010, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 766-72 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Analysis of protein chlorination by mass spectrometry

    Nybo, T., Davies, Michael Jonathan & Rogowska-Wrzesinska, A., 2019, In: Redox Biology. 26, 10 p., UNSP 101236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function: [Meeting Abstract]

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2018, In: Free Radical Biology & Medicine. 120, S1, p. S24-S24 P-41 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

    Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In: Redox Biology. 20, p. 496-513

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205