Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Feb 2009, In : Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Jul 2002, In : Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes

    Morgan, P. E., Sheahan, P. J., Pattison, D. I. & Davies, Michael Jonathan, Aug 2013, In : Free Radical Biology & Medicine. 61, p. 229-42 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, Apr 2002, In : European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Feb 2004, In : Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline

    Morgan, P. E., Pattison, D. I. & Davies, Michael Jonathan, 15 Jan 2012, In : Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In : Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal

    Morgan, P. E., Sheahan, P. J. & Davies, Michael Jonathan, 2014, In : PloS one. 9, 1, 11 p., e86564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In : Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

    Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2011, In : Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage

    Morin, B., Davies, Michael Jonathan & Dean, R. T., 15 Mar 1998, In : Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation

    Morin, B., Bubb, W. A., Davies, Michael Jonathan, Dean, R. T. & Fu, S., Nov 1998, In : Chemical Research in Toxicology. 11, 11, p. 1265-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Analysis of aliphatic amino acid alcohols in oxidized proteins

    Morin, B., Fu, S., Wang, H., Davies, Michael Jonathan & Dean, R. T., 2002, In : Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte

    Murphy, P. G., Davies, Michael Jonathan, Columb, M. O. & Stratford, N., Apr 1996, In : British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction

    Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael Jonathan, Oct 2014, In : Free Radical Research. 48, 10, p. 1256-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress

    Ng, H. H., Leo, C. H., O'Sullivan, K., Alexander, S., Davies, Michael Jonathan, Schiesser, C. H. & Parry, L. J., Mar 2017, In : Biochemical Pharmacology. 128, p. 34-45 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin

    Nielsen, L. R., Lund, Marianne N., Davies, Michael Jonathan, Nielsen, J. H. & Nielsen, S. B., 2018, In : International Dairy Journal. 79, p. 52-61 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I

    Nobécourt, E., Tabet, F., Lambert, G., Puranik, R., Bao, S., Yan, L., Davies, Michael Jonathan, Brown, B. E., Jenkins, A. J., Dusting, G. J., Bonnet, D. J., Curtiss, L. K., Barter, P. J. & Rye, K., Apr 2010, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 766-72 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Analysis of protein chlorination by mass spectrometry

    Nybo, T., Davies, Michael Jonathan & Rogowska-Wrzesinska, A., 2019, In : Redox Biology. 26, 10 p., UNSP 101236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Analysis of extracellular matrix protein chlorination and oxidation by mass spectrometry: [Meeting Abstract]

    Nybo, T., Davies, Michael Jonathan & Rogowska-Wrzesinska, A., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S56-S57 P-40.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, Oct 2018, In : Redox Biology. 19, p. 388-400

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function: [Meeting Abstract]

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2018, In : Free Radical Biology & Medicine. 120, S1, p. S24-S24 P-41 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

    Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 20, p. 496-513

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?

    Ostdal, H., Andersen, H. J. & Davies, Michael Jonathan, 1 Feb 1999, In : Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing

    Park, J. I., Grant, C. M., Davies, Michael Jonathan & Dawes, I. W., 4 Sep 1998, In : The Journal of Biological Chemistry. 273, 36, p. 22921-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A kinetic and ESR investigation of iron(II) oxalate oxidation by hydrogen peroxide and dioxygen as a source of hydroxyl radicals

    Park, J. S., Wood, P. M., Davies, Michael Jonathan, Gilbert, B. C. & Whitwood, A. C., Nov 1997, In : Free Radical Research. 27, 5, p. 447-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Protein-bound kynurenine is a photosensitizer of oxidative damage

    Parker, N. R., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., 1 Nov 2004, In : Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses

    Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., Aug 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    An investigation of the chromium oxidation state of a monoanionic chromium tris(catecholate) complex by X-ray absorption and EPR spectroscopies

    Pattison, D. I., Levina, A., Davies, Michael Jonathan & Lay, P. A., 15 Jan 2001, In : Inorganic Chemistry. 40, 2, p. 214-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity

    Pattison, D. I., Davies, Michael Jonathan, Levina, A., Dixon, N. E. & Lay, P. A., 2001, In : Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds

    Pattison, D. I. & Davies, Michael Jonathan, 2001, In : Chemical Research in Toxicology. 14, 10, p. 1453-64 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    An investigation into the genotoxic species generated during reduction of chromium(VI) by catechol(amine)s

    Pattison, D. I., Lay, P. A. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 2-3, p. 130-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers

    Pattison, D. I., Lay, P. A. & Davies, Michael Jonathan, 26 Jun 2000, In : Inorganic Chemistry. 39, 13, p. 2729-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

    Pattison, D. I., Davies, Michael Jonathan & Hawkins, Clare Louise, Aug 2012, In : Free Radical Research. 46, 8, p. 975-95 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 28 Aug 2007, In : Biochemistry. 46, 34, p. 9853-64 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress

    Pattison, D. I. & Davies, Michael Jonathan, 27 Apr 2004, In : Biochemistry. 43, 16, p. 4799-809 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. One-electron reduction of N-chlorinated and N-brominated species is a source of radicals and bromine atom formation

    Pattison, D. I., O'Reilly, R. J., Skaff, O., Radom, L., Anderson, R. F. & Davies, Michael Jonathan, 21 Mar 2011, In : Chemical Research in Toxicology. 24, 3, p. 371-82 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Photo-oxidation of proteins

    Pattison, D. I., Rahmanto, A. S. & Davies, Michael Jonathan, Jan 2012, In : Photochemical & Photobiological Sciences. 11, 1, p. 38-53 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2009, In : Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies

    Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael Jonathan, 1 Nov 2012, In : Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation

    Pattison, D. I. & Davies, Michael Jonathan, 17 May 2005, In : Biochemistry. 44, 19, p. 7378-87 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, Apr 2003, In : Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Actions of ultraviolet light on cellular structures

    Pattison, D. I. & Davies, Michael Jonathan, 2006, In : E X S. 96, p. 131-57 27 p.

    Research output: Contribution to journalJournal articleResearch

  44. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael Jonathan, 4 Jul 2006, In : Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s

    Pattison, D. I., Dean, R. T. & Davies, Michael Jonathan, 1 Aug 2002, In : Toxicology. 177, 1, p. 23-37 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3

    Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, Michael Jonathan & Winterbourn, C. C., 1 Dec 2010, In : Biochemical Journal. 432, 2, p. 313-21 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Cardiac spheroids as promising in vitro models to study the human heart microenvironment

    Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Figtree, G. A., Davies, Michael Jonathan & Gentile, C., 1 Aug 2017, In : Scientific Reports. 7, 12 p., 7005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Cardiac spheroid co-cultures as a novel in vitro model to study human heart microenvironment

    Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Davies, Michael Jonathan, Figtree, G. & Gentile, C., 2018, In : Journal of Pharmacological and Toxicological Methods. 93, p. 167 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. Cellular effects of peptide and protein hydroperoxides

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Apr 2010, In : Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael Jonathan, 30 Nov 2010, In : Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205