Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. Published

    Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, 15 Jun 1998, In: Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis

    Hawkins, C. L., Brown, Benjamin James & Davies, Michael Jonathan, 15 Nov 2001, In: Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Detection, identification, and quantification of oxidative protein modifications

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In: Journal of Biological Chemistry. 294, 51, p. 19683-19708

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 172, p. 633-651

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals

    Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

    Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In: Biochemical Journal. 416, 3, p. 441-52 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation

    Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In: Biochemical Journal. 365, Pt 3, p. 605-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation

    Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In: Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In: FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Detection and characterisation of radicals in biological materials using EPR methodology

    Hawkins, Clare Louise & Davies, Michael Jonathan, Feb 2014, In: B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins

    Hazell, L. J., Davies, Michael Jonathan & Stocker, R., 1999, In: Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Benzoyl peroxide-induced damage to DNA and its components: direct evidence for the generation of base adducts, sugar radicals, and strand breaks

    Hazlewood, C. & Davies, Michael Jonathan, 1 Aug 1996, In: Archives of Biochemistry and Biophysics. 332, 1, p. 79-91 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin

    He, Jianfei, Becares, E. R., Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael Jonathan & Hägglund, Per Mårten, 2020, In: Redox Biology. 36, 11 p., 101631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains

    Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael Jonathan, Nov 2000, In: Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones

    Headlam, H. A. & Davies, Michael Jonathan, 1 Jun 2002, In: Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals

    Headlam, H. A. & Davies, Michael Jonathan, 1 Jan 2003, In: Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products

    Headlam, H. A. & Davies, Michael Jonathan, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides

    Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael Jonathan, 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The illness beliefs of people newly diagnosed with type 2 diabetes: results from the DESMOND pilot study

    Heller, S., Davies, Michael Jonathan, Khunti, K., Skinner, Timothy & James, P., 1 Jan 2005, Diabetologia.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  23. Published

    Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences

    Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael Jonathan & Spickett, C. M., Apr 2015, In: Free Radical Research. 49, 4, p. 347-73 27 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation

    Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In: Free Radical Biology and Medicine. 153, p. 12-16 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins: [Meeting Abstract]

    Ignasiak-Kciuk, M., Shashikadze, B., Frackowiak, K., Gamon, Luke Francis, Davies, Michael Jonathan & Marciniak, B., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S30-S30 89.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

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