Michael J. Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- Published
Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Apr 2018, In: Free Radical Biology and Medicine. 118, p. 126-136Research output: Contribution to journal › Journal article › peer-review
Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice
Brown, B. E., Kim, C. H. J., Torpy, F. R., Bursill, C. A., McRobb, L. S., Heather, A. K., Davies, Michael J. & van Reyk, D. M., Feb 2014, In: Atherosclerosis. 232, 2, p. 403-9 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Suppressive effect of 1,4-anhydro-4-seleno-D-talitol (SeTal) on atopic dermatitis-like skin lesions in mice through regulation of inflammatory mediators
Voss, G. T., de Oliveira, R. L., Davies, Michael J., Domingues, W. B., Campos, V. F., Soares, M. P., Luchese, C., Schiesser, C. H. & Wilhelm, E. A., 2021, In: Journal of Trace Elements in Medicine and Biology. 67, 10 p., 126795.Research output: Contribution to journal › Journal article › peer-review
Synthesis and antioxidant capacity of 5-selenopyranose derivatives
Storkey, C., Davies, Michael J., White, J. M. & Schiesser, C. H., 14 Sep 2011, In: Chemical communications (Cambridge, England). 47, 34, p. 9693-5 3 p.Research output: Contribution to journal › Journal article › peer-review
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Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
Borges, E. L., Ignasiak, M. T., Velichenko, Y., Perin, G., Hutton, C. A., Davies, Michael J. & Schiesser, C. H., 25 Mar 2018, In: Chemical Communications. 54, 24, p. 2990-2993Research output: Contribution to journal › Journal article › peer-review
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Synthesis and cellular evaluation of click-chemistry probes to study the biological effects of alpha, beta-unsaturated carbonyls
Morozzi, C., Sauerland, M., Gamon, Luke Francis, Manandhar, Asmita, Ulven, Trond & Davies, Michael J., 2022, In: Redox Biology. 52, 8 p., 102299.Research output: Contribution to journal › Journal article › peer-review
Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content
Thallas-Bonke, V., Coughlan, M. T., Tan, A. L., Harcourt, B. E., Morgan, P. E., Davies, Michael J., Bach, L. A., Cooper, M. E. & Forbes, J. M., Jan 2013, In: Nephrology. 18, 1, p. 47-56 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Temperature Activated Diffusion of Radicals through Ion Implanted Polymers
Wakelin, E. A., Davies, Michael J., Bilek, M. M. M. & McKenzie, D. R., 2 Dec 2015, In: A C S Applied Materials and Interfaces. 7, 47, p. 26340-26345 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Tempus fugit horizontal ellipsis
Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 1-1Research output: Contribution to journal › Editorial › peer-review
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The DESMOND educational intervention
Davies, Michael J., Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In: Chronic Illness. 4, 1, p. 38-40 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease
Davies, Michael J. & Hawkins, Clare Louise, 2020, In: Antioxidants & Redox Signaling. 32, 13, p. 957-981Research output: Contribution to journal › Review › peer-review
- Published
The Use of Membrane Filtration to Increase Native Whey Proteins in Infant Formula
Chen, Y., Callanan, M., Shanahan, C., Tobin, J., Gamon, Luke Francis, Davies, Michael J., Giblin, L. & Brodkorb, A., Sep 2021, In: Dairy. 2, 4, p. 515-529Research output: Contribution to journal › Journal article › peer-review
- Published
The association between anxiety and measures of glycaemia in a population-based diabetes screening programme
Aujla, N., Davies, Michael J., Skinner, Timothy, Gray, L. J., Webb, D. R., Srinivasan, B. & Khunti, K., 1 Jul 2011, In: Diabetic Medicine. 28, 7, p. 785-788 4 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The association between depression and health-related quality of life in people with type 2 diabetes: A systematic literature review
Ali, S., Stone, M., Skinner, Timothy, Robertson, N., Davies, Michael J. & Khunti, K., 1 Feb 2010, In: Diabetes/Metabolism Research and Reviews. 26, 2, p. 75-89 15 p.Research output: Contribution to journal › Review › peer-review
- Published
The cysteine residue in beta-lactoglobulin reacts with oxidized tyrosine residues in beta-casein to give casein-lactoglobulin dimers
Doblas, L., Hägglund, Per Mårten, Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Archives of Biochemistry and Biophysics. 733, 7 p., 109482.Research output: Contribution to journal › Journal article › peer-review
- Published
The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing
Park, J. I., Grant, C. M., Davies, Michael J. & Dawes, I. W., 4 Sep 1998, In: The Journal of Biological Chemistry. 273, 36, p. 22921-8 8 p.Research output: Contribution to journal › Journal article › peer-review
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The illness beliefs of people newly diagnosed with type 2 diabetes: results from the DESMOND pilot study
Heller, S., Davies, Michael J., Khunti, K., Skinner, Timothy & James, P., 1 Jan 2005, Diabetologia.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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The immunoproteasome is induced by cytokines and regulates apoptosis in human islets
Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, Seyed Mojtaba, De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael J., Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin: cholesterol acyltransferase
Nobecourt, E., Davies, Michael J., Brown, B. E., Curtiss, L. K., Bonnet, D. J., Charlton, F., Januszewski, A. S., Jenkins, A. J., Barter, P. J. & Rye, K. -., Mar 2007, In: Diabetologia. 50, 3, p. 643-653 11 p.Research output: Contribution to journal › Journal article › peer-review
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The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes
Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael J., Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In: Archives of Biochemistry and Biophysics. 689, 7 p., 108443.Research output: Contribution to journal › Journal article › peer-review
The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
Graham, G. G., Davies, Michael J., Day, R. O., Mohamudally, A. & Scott, K. F., Jun 2013, In: Inflammopharmacology. 21, 3, p. 201-32 32 p.Research output: Contribution to journal › Journal article › peer-review
The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages
Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael J., 15 Aug 2010, In: Biochemical Journal. 430, 1, p. 161-9 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues
Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael J., 1 Jan 2016, In: Free Radical Biology & Medicine. 90, p. 195-205 11 p.Research output: Contribution to journal › Journal article › peer-review
The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies
Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael J., 1 Nov 2012, In: Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.Research output: Contribution to journal › Journal article › peer-review
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The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice
Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael J., May 2015, In: Atherosclerosis. 240, 1, p. 234-241 8 p.Research output: Contribution to journal › Journal article › peer-review
The oxidative environment and protein damage
Davies, Michael J., 17 Jan 2005, In: B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.Research output: Contribution to journal › Journal article › peer-review
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The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function
Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael J. & López-Alarcón, C., Nov 2017, In: Free Radical Biology and Medicine. 112, p. 60-68 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus
Aujla, N., Abrams, K. R., Davies, Michael J., Taub, N., Skinner, Timothy & Khunti, K., 9 Nov 2009, In: PLoS ONE. 4, 11, e7755.Research output: Contribution to journal › Journal article › peer-review
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The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: A comparison of two screening tools
Aujla, N., Skinner, Timothy, Khunti, K. & Davies, Michael J., 1 Aug 2010, In: Diabetic Medicine. 27, 8, p. 896-905 10 p.Research output: Contribution to journal › Journal article › peer-review
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The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage
Morin, B., Davies, Michael J. & Dean, R. T., 15 Mar 1998, In: Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.Research output: Contribution to journal › Journal article › peer-review
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The retina: oxidative stress and diabetes
van Reyk, D. M., Gillies, M. C. & Davies, Michael J., 2003, In: Redox Report (Online). 8, 4, p. 187-92 6 p.Research output: Contribution to journal › Journal article › peer-review
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The role of RNA oxidation in islet dysfunction in Type 2 diabetes
Sileikaite, Inga, Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1 , p. S37-S38Research output: Contribution to journal › Conference abstract in journal
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael J., Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.Research output: Contribution to journal › Journal article › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael J., 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.Research output: Contribution to journal › Journal article › peer-review
The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael J., Iozzo, R. V. & Whitelock, J. M., Apr 2014, In: Matrix Biology. 35, p. 112-22 11 p.Research output: Contribution to journal › Journal article › peer-review
The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction
Talib, J., Kwan, J., Suryo Rahmanto, A., Witting, P. K. & Davies, Michael J., 1 Jan 2014, In: Biochemical Journal. 457, 1, p. 89-97 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage
Skjoldager, N., Blanner Bang, M., Rykaer, M., Björnberg, O., Davies, Michael J., Svensson, B., Harris, P. & Hägglund, Per Mårten, Apr 2017, In: Scientific Reports. 7, 10 p., 46282.Research output: Contribution to journal › Journal article › peer-review
The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study
Skaff, O., Pattison, D. I. & Davies, Michael J., 5 Aug 2008, In: Biochemistry. 47, 31, p. 8237-45 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase
Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael J., 27 Mar 2015, In: Free Radical Research. 49, 6, p. 743-9 7 p.Research output: Contribution to journal › Journal article › peer-review
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Tryptophan and Cysteine residues mediate chain reactions and propagation of oxidative damage in concentrated casein solutions
Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 562 1 p.Research output: Contribution to journal › Conference abstract in journal
Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants
Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael J., Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In: Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.Research output: Contribution to journal › Journal article › peer-review
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation
Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael J., 15 Dec 2008, In: Biochemical Journal. 416, 3, p. 441-52 12 p.Research output: Contribution to journal › Journal article › peer-review
Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage
Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael J., 15 Mar 2008, In: Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites
Leinisch, F., Mariotti, M., Andersen, S. H., Lindemose, Søren, Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael J., 2020, In: Scientific Reports. 10, 1, 11 p., 3106.Research output: Contribution to journal › Journal article › peer-review
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Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation
Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael J. & Marciniak, B., 2020, In: Free Radical Biology and Medicine. 153, p. 12-16 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications
Rykær, M., Svensson, B., Davies, Michael J. & Hägglund, Per Mårten, 3 Nov 2017, In: Journal of Proteome Research. 16, 11, p. 3978-3988 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Utility of risk factors when screening for diabetes mellitus
Tringham, J. R., Davies, Michael J., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Jan 2005, Diabetes.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study
Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael J., 1 Jul 2008, In: Patient Education and Counseling. 72, 1, p. 88-93 6 p.Research output: Contribution to journal › Journal article › peer-review
What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., May 2009, In: Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Whey proteins: targets of oxidation, or mediators of redox protection
Giblin, L., Yalcin, A. S., Bicim, G., Kramer, A. C., Chen, Z., Callanan, M. J., Arranz, E. & Davies, Michael J., 2019, In: Free Radical Research. 53, S1, p. 1136–1152 17 p.Research output: Contribution to journal › Review › peer-review
ID: 38036205
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Protein oxidation and peroxidation
Research output: Contribution to journal › Review › peer-review
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Research output: Contribution to journal › Journal article › peer-review
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
Research output: Contribution to journal › Journal article › peer-review
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