Michael J. Davies

Michael J. Davies

Professor

ORCID: 0000-0002-5196-6919

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  1. Published

    Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space

    Indo, H. P., Majima, H. J., Terada, M., Suenaga, S., Tomita, K., Yamada, S., Higashibata, A., Ishioka, N., Kanekura, T., Nonaka, I., Hawkins, Clare Louise, Davies, Michael J., Clair, D. K. S. & Mukai, C., 16 Dec 2016, In: Scientific Reports. 6, 10 p., 39015.

    Research output: Contribution to journal › Journal article › peer-review

  2. Published

    Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula

    Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 68-81

    Research output: Contribution to journal › Journal article › peer-review

  3. Published

    Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula: [Meeting Abstract]

    Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, Supplement 1, p. S47 1 p., P-8.

    Research output: Contribution to journal › Conference abstract in journal

  4. Published

    Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols

    Karimi, M., Crossett, B., Cordwell, S. J., Pattison, David & Davies, Michael J., 2020, In: Free Radical Biology and Medicine. 154, p. 62-74 13 p.

    Research output: Contribution to journal › Journal article › peer-review

  5. Published

    Chasing Great Paths of Helmut “Oxidative Stress” Sies

    Majima, H., Indo, H., Nakanishi, I., Suenaga, S., Matsumoto, K., Matsui, H., Minamiyami, Y., Ichikawa, H., Yen, H., Hawkins, C., Davies, Michael J., Ozawa, T. & St. Clair, D., 2016, In: Archives of Biochemistry and Biophysics. 595, p. 54-60 7 p.

    Research output: Contribution to journal › Journal article › peer-review

  6. Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals: role of oxidizable amino acid residues

    Arenas, A., López-Alarcón, C., Kogan, M., Lissi, E., Davies, Michael J. & Silva, E., 18 Jan 2013, In: Chemical Research in Toxicology. 26, 1, p. 67-77 11 p.

    Research output: Contribution to journal › Journal article › peer-review

  7. Published

    Chlorination and nitration of extracellular matrix by inflammatory myeloperoxidase-derived oxidants in the presence of nitrite

    Xu, Shuqi, Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 566 1 p.

    Research output: Contribution to journal › Conference abstract in journal

  8. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function: [Meeting Abstract]

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., 2018, In: Free Radical Biology & Medicine. 120, S1, p. S24-S24 P-41 .

    Research output: Contribution to journal › Conference abstract in journal › peer-review

  9. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., Oct 2018, In: Redox Biology. 19, p. 388-400

    Research output: Contribution to journal › Journal article › peer-review

  10. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

    Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 20, p. 496-513

    Research output: Contribution to journal › Journal article › peer-review

  11. Published

    Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity

    Pattison, D. I., Davies, Michael J., Levina, A., Dixon, N. E. & Lay, P. A., 2001, In: Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.

    Research output: Contribution to journal › Journal article › peer-review

  12. Published

    Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): implications for foam cell formation in atherosclerosis

    Ismael, F. O., Proudfoot, J. M., Brown, B. E., van Reyk, D. M., Croft, K. D., Davies, Michael J. & Hawkins, C. L., May 2015, In: Archives of Biochemistry and Biophysics. 573, p. 40-51 12 p.

    Research output: Contribution to journal › Journal article › peer-review

  13. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells

    Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael J. & Hawkins, Clare Louise, Dec 2013, In: Free Radical Biology & Medicine. 65, p. 1352-62 11 p.

    Research output: Contribution to journal › Journal article › peer-review

  14. Published

    Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein

    Knott, H. M., Baoutina, A., Davies, Michael J. & Dean, R. T., 15 Apr 2002, In: Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.

    Research output: Contribution to journal › Journal article › peer-review

  15. Published

    Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Dalyb, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Olivere, L., 1 Mar 2011, In: Psychology and Health. 26, 3, p. 321-335 15 p.

    Research output: Contribution to journal › Journal article › peer-review

  16. Published

    Competitive kinetics as a tool to determine rate constants for reduction of ferrylmyoglobin by food components

    Jongberg, S., Lund, Marianne N., Pattison, David, Skibsted, Leif Horsfelt & Davies, Michael J., 2016, In: Food Chemistry. 199, p. 36-41 6 p.

    Research output: Contribution to journal › Journal article › peer-review

  17. Published

    Competitive reduction of perferrylmyoglobin radicals by protein thiols and plant phenols

    Jongberg, S., Lund, Marianne N., Skibsted, Leif Horsfelt & Davies, Michael J., 2014, In: Journal of Agricultural and Food Chemistry. 62, 46, p. 11279-11288 10 p.

    Research output: Contribution to journal › Journal article › peer-review

  18. Computational design of effective, bioinspired HOCl antioxidants: the role of intramolecular Cl+ and H+ shifts

    Karton, A., O'Reilly, R. J., Pattison, D. I., Davies, Michael J. & Radom, L., 21 Nov 2012, In: Journal of the American Chemical Society. 134, 46, p. 19240-5 6 p.

    Research output: Contribution to journal › Journal article › peer-review

  19. Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions

    Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.

    Research output: Contribution to journal › Journal article › peer-review

  20. Published

    Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action

    Tiwari, M. K., Hägglund, Per Mårten, Møller, I. M., Davies, Michael J. & Bjerrum, Morten Jannik, 2019, In: Redox Biology. 26, 15 p., 101262.

    Research output: Contribution to journal › Journal article › peer-review

  21. Published

    Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions

    Mariotti, M., Rogowska-Wrzesinska, A., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Journal of Biological Chemistry. 296, 100360.

    Research output: Contribution to journal › Journal article › peer-review

  22. Published

    Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development

    Tweeddale, H. J., Hawkins, Clare Louise, Janmie, J. F., Truscott, R. J. W. & Davies, Michael J., Oct 2016, In: Free Radical Research. 50, 10, p. 1116-1130 15 p.

    Research output: Contribution to journal › Journal article › peer-review

  23. Published

    Crosslinking of human plasma C-reactive protein to human serum albumin via disulfide bond oxidation

    Jiang, S., Hägglund, Per Mårten, Carroll, L., Rasmussen, L. M. & Davies, Michael J., 2021, In: Redox Biology. 41, 17 p., 101925.

    Research output: Contribution to journal › Journal article › peer-review

  24. Published

    Crowding modulates the glycation of plasma proteins: In vitro analysis of structural modifications to albumin and transferrin and identification of sites of modification

    Fuentes Lemus, Eduardo, Reyes, J. S., López-Alarcón, C. & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 193, p. 551-566 16 p.

    Research output: Contribution to journal › Journal article › peer-review

  25. Published

    Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

    Sies, H., Belousov, V. V., Chandel, N. S., Davies, Michael J., Jones, D. P., Mann, G. E., Murphy, M. P., Yamamoto, M. & Winterbourn, C., 2022, In: Nature Reviews Molecular Cell Biology. 23, p. 499–515

    Research output: Contribution to journal › Review › peer-review

  26. Degradation of extracellular matrix and its components by hypobromous acid

    Rees, M. D., McNiven, T. N. & Davies, Michael J., 15 Jan 2007, In: Biochemical Journal. 401, 2, p. 587-96 10 p.

    Research output: Contribution to journal › Journal article › peer-review

  27. Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid

    Kennett, E. C. & Davies, Michael J., 1 Sep 2008, In: Free Radical Biology & Medicine. 45, 5, p. 716-25 10 p.

    Research output: Contribution to journal › Journal article › peer-review

  28. Published

    Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation

    Hawkins, C. L. & Davies, Michael J., Jun 1998, In: Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.

    Research output: Contribution to journal › Journal article › peer-review

  29. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism

    Kennett, E. C. & Davies, Michael J., 15 Apr 2007, In: Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.

    Research output: Contribution to journal › Journal article › peer-review

  30. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis

    Moheimani, F., Morgan, P. E., van Reyk, D. M. & Davies, Michael J., Jun 2010, In: B B A - Reviews on Cancer. 1802, 6, p. 561-71 11 p.

    Research output: Contribution to journal › Journal article › peer-review

  31. Published

    Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cost effectiveness analysis

    Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M. E., Campbell, M. J., Heller, S., Khunti, K., Skinner, Timothy & Davies, Michael J., 26 Aug 2010, In: BMJ (Online). 341, 7770, c4093.

    Research output: Contribution to journal › Journal article › peer-review

  32. Published

    Depressive symptoms in the first year from diagnosis of Type 2 diabetes: Results from the DESMOND trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Aug 2010, In: Diabetic Medicine. 27, 8, p. 965-967 3 p.

    Research output: Contribution to journal › Journal article › peer-review

  33. Published

    Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis

    Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael J. & Siebuhr, A. S., 2020, In: Scientific Reports. 10, 1, 10 p., 17300.

    Research output: Contribution to journal › Journal article › peer-review

  34. Detection and characterisation of radicals in biological materials using EPR methodology

    Hawkins, Clare Louise & Davies, Michael J., Feb 2014, In: B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.

    Research output: Contribution to journal › Review › peer-review

  35. Published

    Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods

    Davies, Michael J., 2016, In: Methods. 109, p. 21-30 10 p.

    Research output: Contribution to journal › Journal article › peer-review

  36. Published

    Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques

    Woods, A. A., Linton, S. M. & Davies, Michael J., 1 Mar 2003, In: Biochemical Journal. 370, Pt 2, p. 729-35 7 p.

    Research output: Contribution to journal › Journal article › peer-review

  37. Published

    Detection, identification, and quantification of oxidative protein modifications

    Hawkins, Clare Louise & Davies, Michael J., 2019, In: Journal of Biological Chemistry. 294, 51, p. 19683-19708

    Research output: Contribution to journal › Review › peer-review

  38. Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses

    Gad, N. A., Mizdrak, J., Pattison, D. I., Davies, Michael J., Truscott, R. J. W. & Jamie, J. F., Feb 2014, In: Investigative Ophthalmology & Visual Science. 55, 2, p. 849-55 7 p.

    Research output: Contribution to journal › Journal article › peer-review

  39. Published

    Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

    Weber, D., Davies, Michael J. & Grune, T., 1 Aug 2015, In: Redox Biology. 5, p. 367-380 14 p.

    Research output: Contribution to journal › Review › peer-review

  40. Published

    Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study

    Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In: Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.

    Research output: Contribution to journal › Journal article › peer-review

  41. Published

    Diabetes screening anxiety and beliefs

    Skinner, Timothy, Davies, Michael J., Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In: Diabetic Medicine. 22, 11, p. 1497-1502 6 p.

    Research output: Contribution to journal › Journal article › peer-review

  42. Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease

    Leung, C., Herath, C. B., Jia, Z., Andrikopoulos, S., Brown, B. E., Davies, Michael J., Rivera, L. R., Furness, J. B., Forbes, J. M. & Angus, P. W., 21 Sep 2016, In: World Journal of Gastroenterology. 22, 35, p. 8026-8040 15 p.

    Research output: Contribution to journal › Journal article › peer-review

  43. Published

    Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper

    Stadler, N., Lindner, R. A. & Davies, Michael J., 2004, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.

    Research output: Contribution to journal › Journal article › peer-review

  44. Published

    Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes

    Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael J., 1998, In: Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.

    Research output: Contribution to journal › Journal article › peer-review

  45. Published

    Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation

    Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael J., 27 Jul 2011, In: Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.

    Research output: Contribution to journal › Journal article › peer-review

  46. Published

    Dynein regulates Kv7.4 channel trafficking from the cell membrane

    van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

    Research output: Contribution to journal › Journal article › peer-review

  47. Published

    EPR spin trapping of protein radicals

    Davies, Michael J. & Hawkins, Clare Louise, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journal › Journal article › peer-review

  48. Published

    EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers

    Pattison, D. I., Lay, P. A. & Davies, Michael J., 26 Jun 2000, In: Inorganic Chemistry. 39, 13, p. 2729-39 11 p.

    Research output: Contribution to journal › Journal article › peer-review

  49. Published

    Early events in copper-ion catalyzed oxidation of α-synuclein

    Tiwari, M. K., Leinisch, F., Sahin, C., Møller, I. M., Otzen, D. E., Davies, Michael J. & Bjerrum, Morten Jannik, 2018, In: Free Radical Biology & Medicine. 121, p. 38-50 13 p.

    Research output: Contribution to journal › Journal article › peer-review

  50. Published

    Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin

    Krämer, A. C. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.

    Research output: Contribution to journal › Journal article › peer-review

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