Michael J. Davies

Professor

Inflammation, Metabolism and Oxidation
Blegdamsvej 3B
2200 København N
- davies@sund.ku.dk
- https://bmi.ku.dk/english/research/inflammation-metabolism-and-oxidation/davies-group/
Mobile: +4523649445

ORCID: 0000-0002-5196-6919

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2024
Published
Oxidation of the active site cysteine residue of glyceraldehyde-3-phosphate dehydrogenase to the hyper-oxidized sulfonic acid form is favored under crowded conditions
Glover, M. R., Davies, Michael J. & Fuentes Lemus, Eduardo, 2024, In: Free Radical Biology and Medicine. 212, p. 1-9 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Elevated levels of iodide promote peroxidase-mediated protein iodination and inhibit protein chlorination
Jokumsen, Kathrine Væver, Huhle, V. H., Hägglund, Per Mårten, Davies, Michael J. & Gamon, Luke Francis, 2024, In: Free Radical Biology and Medicine. 220, p. 207-221 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Proteomic analysis of the extracellular matrix of human atherosclerotic plaques shows marked changes between plaque types
Lorentzen, Lasse Gøbel, Yeung, K., Eldrup, Nikolaj, Eiberg, Jonas Peter, Sillesen, Henrik & Davies, Michael J., 2024, In: Matrix Biology Plus. 21, 14 p., 100141.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Competitive oxidation of key pentose phosphate pathway enzymes modulates the fate of intermediates and NAPDH production
Reyes, J. S., Cortés-Ríos, J., Fuentes Lemus, Eduardo, Rodriguez-Fernandez, M., Davies, Michael J. & López-Alarcón, C., 2024, In: Free Radical Biology and Medicine. 222, p. 505-518
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Modification of extracellular matrix proteins by oxidants and electrophiles
Yang-Jensen, Karen Chuxian, Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael J., 2024, In: Biochemical Society Transactions. 52, 3, p. 1199-1217
Research output: Contribution to journal › Review › Research › peer-review
2023
Published
Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules
Anghinoni, J. M., Birmann, P. T., da Rocha, M. J., Gomes, C. S., Davies, Michael J., Brüning, C. A., Savegnago, L. & Lenardão, E. J., 2023, In: Molecules. 28, 21, p. 1-45 7349.
Research output: Contribution to journal › Review › Research › peer-review
Published
Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation
Campolo, N., Mastrogiovanni, M., Mariotti, M., Issoglio, F. M., Estrin, D., Hägglund, Per Mårten, Grune, T., Davies, Michael J., Bartesaghi, S. & Radi, R., 2023, In: Journal of Biological Chemistry. 299, 3, 22 p., 102941.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells
Clemen, R., Fuentes Lemus, Eduardo, Bekeschus, S. & Davies, Michael J., 2023, In: Redox Biology. 65, 14 p., 102835.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Myeloperoxidase Alters Lung Cancer Cell Function to Benefit Their Survival
Cosic-Mujkanovic, N., Valadez-Cosmes, P., Maitz, K., Lueger, A., Mihalic, Z. N., Runtsch, M. C., Kienzl, M., Davies, Michael J., Chuang, Christine, Heinemann, A., Schicho, R., Marsche, G. & Kargl, J., 2023, In: Antioxidants. 12, 8, 17 p., 1587.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The cysteine residue in beta-lactoglobulin reacts with oxidized tyrosine residues in beta-casein to give casein-lactoglobulin dimers
Doblas, L., Hägglund, Per Mårten, Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Archives of Biochemistry and Biophysics. 733, 7 p., 109482.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Complexation of AAPH (2,2′-azobis(2-methylpropionamidine) dihydrochloride) with cucurbit[7]uril enhances the yield of AAPH-derived radicals
Forero-Girón, A. C., Fuentealba, D., Mariño-Ocampo, N., Gutiérrez-Oliva, S., Herrera, B., Toro-Labbé, A., Fuentes Lemus, Eduardo, Davies, Michael J., Aliaga, M. E. & López-Alarcón, C., 2023, In: Journal of Molecular Liquids. 389, 9 p., 122840.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of crowding, compartmentalization and nanodomains on protein modification and redox signaling – current state and future challenges
Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 196, p. 81-92
Research output: Contribution to journal › Review › Research › peer-review
Published
The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production
Fuentes Lemus, Eduardo, Reyes, J. S., Figueroa, J. D., Davies, Michael J. & López-Alarcón, C., 2023, In: Biochemical Society Transactions. 51, 6, p. 2173–2187
Research output: Contribution to journal › Review › Research › peer-review
Published
The structure of model and peptide disulfides markedly affects their reactivity and products formed with singlet oxygen
Gao, Qing, Grzyb, K., Gamon, Luke Francis, Ogilby, P. R., Pędziński, T. & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 207, p. 320-329
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Exposure to peroxynitrite impacts the ability of anastellin to modulate the structure of extracellular matrix
He, Jianfei, Chuang, Christine, Hawkins, Clare Louise, Davies, Michael J. & Hägglund, Per Mårten, 2023, In: Free Radical Biology and Medicine. 206, p. 83-93 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The inflammatory oxidant peroxynitrous acid modulates the structure and function of the recombinant human V3 isoform of the extracellular matrix proteoglycan versican
Jørgensen, Sara Marthedal, Lorentzen, Lasse Gøbel, Hammer, A., Hoefler, G., Malle, E., Chuang, Christine & Davies, Michael J., 2023, In: Redox Biology. 64, 19 p., 102794.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxygen Exposure and Tolerance Shapes the Cell Wall-Associated Lipids of the Skin Commensal Cutibacterium acnes
Popa, I., Touboul, D., Andersson, T., Fuentes Lemus, Eduardo, Santerre, C., Davies, Michael J. & Lood, R., 2023, In: Microorganisms. 11, 9, 15 p., 2260.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peroxyl radicals modify 6-phosphogluconolactonase from Escherichia coli via oxidation of specific amino acids and aggregation which inhibits enzyme activity
Reyes, J. S., Fuentes Lemus, Eduardo, Romero, J., Arenas, F., Fierro, A., Davies, Michael J. & López-Alarcón, C., 2023, In: Free Radical Biology and Medicine. 204, p. 118-127
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Identification of galectin-1 and other cellular targets of alpha,beta-unsaturated carbonyl compounds, including dimethylfumarate, by use of click-chemistry probes
Sauerland, Max Benjamin, Helm, C., Lorentzen, Lasse Gøbel, Manandhar, Asmita, Ulven, Trond, Gamon, Luke Francis & Davies, Michael J., 2023, In: Redox Biology. 59, 15 p., 102560.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Detrimental Actions of Chlorinated Nucleosides on the Function and Viability of Insulin-Producing Cells
Sileikaite-Morvaközi, I., Hansen, W. H., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2023, In: International Journal of Molecular Sciences. 24, 19, 13 p., 14585.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids
Trammell, Sam, Gamon, Luke Francis, Gotfryd, K., Michler, Katja Thorøe, Alrehaili, B. D., Rix, I., Knop, Filip Krag, Gourdon, Pontus Emanuel, Lee, Y. K., Davies, Michael J., Gillum, M. P. & Grevengoed, Trisha Jean, 2023, In: Journal of Lipid Research. 64, 9, 9 p., 100361.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Treating atopic-dermatitis-like skin lesions in mice with gelatin-alginate films containing 1,4-anhydro-4-seleno-D-talitol (SeTal)
Voss, G. T., Davies, Michael J., Schiesser, C. H., de Oliveira, R. L., Nornberg, A. B., Soares, V. R., Barcellos, A. M., Luchese, C., Fajardo, A. R. & Wilhelm, E. A., 2023, In: International Journal of Pharmaceutics. 642, 13 p., 123174.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity
Wang, Y., Hammer, A., Hoefler, G., Malle, E., Hawkins, Clare Louise, Chuang, Christine & Davies, Michael J., 2023, In: Antioxidants. 12, 2, 25 p., 420.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Identification and quantification of protein nitration sites in human coronary artery smooth muscle cells in the absence and presence of peroxynitrous acid/peroxynitrite
Xu, Shuqi, Chuang, Christine, Hawkins, Clare Louise, Hägglund, Per Mårten & Davies, Michael J., 2023, In: Redox Biology. 64, 13 p., 102799.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Genotoxicity assessment of 1,4-anhydro-4-seleno-D-talitol (SeTal) in human liver HepG2 and HepaRG cells
di Vito, R., Acito, M., Fatigoni, C., Schiesser, C. H., Davies, Michael J., Mangiavacchi, F., Villarini, M., Santi, C. & Moretti, M., 2023, In: Toxicology. 499, 153663.
Research output: Contribution to journal › Journal article › Research › peer-review
2022
Published
Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**
Bolding, J. E., Martín-Gago, P., Rajabi, N., Gamon, Luke Francis, Hansen, T. N., Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Davies, Michael J. & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 47, 11 p., e202204565.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Adduction reactions of alpha,beta-unsaturated aldehydes to proteins
Davies, Michael J., 2022, In: Toxicology Letters. 368, Suppl, p. S62-S62 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
In memoriam: Emeritus Professor Robin L. Willson
Davies, Michael J., Davies, K. J. A., Halliwell, B., Jackson, M. J., Mann, G. E., Poli, G., Radi, R., Riley, P. A., Sies, H., Ward, J. F., Wardman, P. & Willson, J., 2022, In: Free Radical Research. 56, 7-8, p. 572-576 5 p.
Research output: Contribution to journal › Journal article › Research
Published
Role of amino acid oxidation and protein unfolding in peroxyl radical and peroxynitrite-induced inactivation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides
Figueroa, J. D., Fuentes Lemus, Eduardo, Reyes, J. S., Loaiza, M., Aliaga, M. E., Fierro, A., Leinisch, F., Hägglund, Per Mårten, Davies, Michael J. & López-Alarcón, C., 2022, In: Free Radical Biology and Medicine. 190, p. 292-306
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Crowding modulates the glycation of plasma proteins: In vitro analysis of structural modifications to albumin and transferrin and identification of sites of modification
Fuentes Lemus, Eduardo, Reyes, J. S., López-Alarcón, C. & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 193, p. 551-566 16 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative Crosslinking of Peptides and Proteins: Mechanisms of Formation, Detection, Characterization and Quantification
Fuentes Lemus, Eduardo, Hägglund, Per Mårten, López-Alarcón, C. & Davies, Michael J., 1 Jan 2022, In: Molecules. 27, 1, p. 1-31 15.
Research output: Contribution to journal › Review › Research › peer-review
Published
Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells
He, Jianfei, Steffen, Jonas Hyld, Thulstrup, Peter Waaben, Pedersen, J. N., Sauerland, Max Benjamin, Otzen, D. E., Hawkins, Clare Louise, Gourdon, Pontus Emanuel, Davies, Michael J. & Hägglund, Per Mårten, 2022, In: Scientific Reports. 12, 1, 15 p., 22051.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidant-mediated modification and cross-linking of beta-2-microglobulin
Jiang, S., Fuentes Lemus, Eduardo & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 187, p. 59-71
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peroxynitrous acid-modified extracellular matrix alters gene and protein expression in human coronary artery smooth muscle cells and induces a pro-inflammatory phenotype
Jørgensen, Sara Marthedal, Lorentzen, Lasse Gøbel, Chuang, Christine & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 186, p. 43-52
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Proteomic Characterization of Atherosclerotic Lesions in Situ Using Percutaneous Coronary Intervention Angioplasty Balloons-Brief Report
Lorentzen, Lasse Gøbel, Hansen, G. M., Iversen, Kasper, Bundgård, Henning & Davies, Michael J., 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 7, p. 857-864
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Synthesis and cellular evaluation of click-chemistry probes to study the biological effects of alpha, beta-unsaturated carbonyls
Morozzi, C., Sauerland, M., Gamon, Luke Francis, Manandhar, Asmita, Ulven, Trond & Davies, Michael J., 2022, In: Redox Biology. 52, 8 p., 102299.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Murphy, M. P., Bayir, H., Belousov, V., Chang, C. J., Davies, K. J. A., Davies, M. J., Dick, T. P., Finkel, T., Forman, H. J., Janssen-Heininger, Y., Gems, D., Kagan, V. E., Kalyanaraman, B., Larsson, N. G., Milne, G. L., Nyström, T., Poulsen, H. E., Radi, R., Van Remmen, H., Schumacker, P. T. & 5 others, Thornalley, P. J., Toyokuni, S., Winterbourn, C. C., Yin, H. & Halliwell, B., 2022, In: Nature Metabolism. 4, 6, p. 651-662
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC
Perez-Hernandez, M., van Opbergen, C. J. M., Bagwan, N., Vissing, C. R., Marron-Linares, G. M., Zhang, M., Vega, E. T., Sorrentino, A., Drici, L., Sulek, K., Zhai, R., Hansen, F. B., Christensen, A. H., Boesgaard, S., Gustafsson, F., Rossing, K., Small, E. M., Davies, M. J., Rothenberg, E., Sato, P. Y. & 6 others, Cerrone, M., Jensen, Thomas Hartvig Lindkær, Qvortrup, Klaus, Bundgård, Henning, Delmar, M. & Lundby, Alicia, 2022, In: Circulation. 146, 11, p. 851-867
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Implications of differential peroxyl radical-induced inactivation of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase for the pentose phosphate pathway
Reyes, J. S., Fuentes Lemus, Eduardo, Figueroa, J. D., Rojas, J., Fierro, A., Arenas, F., Hägglund, Per Mårten, Davies, Michael J. & López-Alarcón, C., 2022, In: Scientific Reports. 12, 1, 19 p., 21191.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Reaction of cysteine residues with oxidized tyrosine residues mediates cross-linking of photo-oxidized casein proteins
Rossi, C., Fuentes Lemus, Eduardo & Davies, Michael J., 2022, In: Food Chemistry. 385, 7 p., 132667.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Structural Basis for Dityrosine-Mediated Inhibition of alpha-Synuclein Fibrillization
Sahin, C., Osterlund, E. C., Osterlund, N., Costeira-Paulo, J., Pedersen, J. N., Christiansen, G., Nielsen, J., Grønnemose, A. L., Amstrup, S. K., Tiwari, M. K., Rao, R. S. P., Bjerrum, Morten Jannik, Ilag, L. L., Davies, Michael J., Marklund, E. G., Pedersen, J. S., Landreh, M., Moller, I. M., Jorgensen, T. J. D. & Otzen, D. E., 2022, In: Journal of the American Chemical Society. 144, 27, p. 11949-11954 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Electrophile versus oxidant modification of cysteine residues: Kinetics as a key driver of protein modification
Sauerland, Max Benjamin & Davies, Michael J., 30 Sep 2022, In: Archives of Biochemistry and Biophysics. 727, 10 p., 109344.
Research output: Contribution to journal › Review › Research › peer-review
Published
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
Sies, H., Belousov, V. V., Chandel, N. S., Davies, Michael J., Jones, D. P., Mann, G. E., Murphy, M. P., Yamamoto, M. & Winterbourn, C., 2022, In: Nature Reviews Molecular Cell Biology. 23, p. 499–515
Research output: Contribution to journal › Review › Research › peer-review
Published
Activation and Inhibition of Human Matrix Metalloproteinase-9 (MMP9) by HOCl, Myeloperoxidase and Chloramines
Wang, Y., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., Aug 2022, In: Antioxidants. 11, 8, 22 p., 1616.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage
Xu, Shuqi, Chuang, Christine, Malle, E., Gamon, Luke Francis, Hawkins, Clare Louise & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 188, p. 162-174
Research output: Contribution to journal › Journal article › Research › peer-review
2021
Published
The Use of Membrane Filtration to Increase Native Whey Proteins in Infant Formula
Chen, Y., Callanan, M., Shanahan, C., Tobin, J., Gamon, Luke Francis, Davies, Michael J., Giblin, L. & Brodkorb, A., Sep 2021, In: Dairy. 2, 4, p. 515-529
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Anthocyanin complex niosome gel accelerates oral wound healing: In vitro and clinical studies
Damrongrungruang, T., Paphangkorakit, J., Limsitthichaikoon, S., Khampaenjiraroch, B., Davies, Michael J., Sungthong, B. & Priprem, A., 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 37, 14 p., 102423.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
"What, where and how much? Key challenges in protein oxidation"
Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 165, Suppl. 1, p. 15-15 Suppl. 13-1.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
Davies, Michael J., 2021, In: Pharmacology and Therapeutics. 218, 23 p., 107685.
Research output: Contribution to journal › Review › Research › peer-review
Published
Reactivity of Peroxidase-Derived Oxidants with Proteins, Glycoproteins and Proteoglycans
Davies, Michael J., 1 Jan 2021, Mammalian Heme Peroxidases: Diverse Roles in Health and Disease. CRC Press, p. 53-77
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues
Flouda, K., Gammelgaard, Bente, Davies, Michael J. & Hawkins, Clare Louise, May 2021, In: Redox Biology. 41, 101873.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage
Flouda, K., Mercer, J., Davies, Michael J. & Hawkins, Clare Louise, 2021, In: Free Radical Biology & Medicine. 166, p. 165-177
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of macromolecular crowding on protein oxidation: Consequences on the rate, extent and oxidation pathways
Fuentes Lemus, Eduardo, Reyes, J. S., Gamon, Luke Francis, López-Alarcón, C. & Davies, Michael J., 2021, In: Redox Biology. 48, 15 p., 102202.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage
Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Food Hydrocolloids. 121, 16 p., 107060.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidation of lysozyme induced by peroxyl radicals involves amino acid modifications, loss of activity, and formation of specific crosslinks
Fuentes Lemus, Eduardo, Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Davies, Michael J. & Lopez-Alarcon, C., 2021, In: Free Radical Biology and Medicine. 167, p. 258-270
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative damage on proteins is enhanced in crowded environments
Fuentes Lemus, Eduardo, Gamon, Luke Francis, Lopez-Alarcon, C. & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. S31-S32
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Tryptophan and Cysteine residues mediate chain reactions and propagation of oxidative damage in concentrated casein solutions
Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 562 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats
Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael J., 2021, In: Scientific Reports. 11, 1, 18 p., 12712.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage
Hawkins, Clare Louise & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 172, p. 633-651
Research output: Contribution to journal › Review › Research › peer-review
Published
Hypoxia of human endothelial artery wall cells affects arterial extracellular matrix remodelling and contributes to atherosclerosis development
Huang, S., Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 563 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Crosslinking of human plasma C-reactive protein to human serum albumin via disulfide bond oxidation
Jiang, S., Hägglund, Per Mårten, Carroll, L., Rasmussen, L. M. & Davies, Michael J., 2021, In: Redox Biology. 41, 17 p., 101925.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation
Jiang, S., Carroll, L., Mariotti, M., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Redox Biology. 41, 16 p., 101874.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidation of protein disulfide bonds by singlet oxygen gives rise to glutathionylated proteins
Jiang, S., Carroll, L., Rasmussen, L. M. & Davies, Michael J., 2021, In: Redox Biology. 38, 16 p., 101822.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Phenotypic changes to vascular smooth muscle cells induced by extracellular matrix modification
Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology & Medicine. 165, Suppl. 1, p. 36-37 NC38.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Phenotypic changes to vascular smooth muscle cells induced by oxidant-modified extracellular matrix
Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 165, 1 p., NC38.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions
Mariotti, M., Rogowska-Wrzesinska, A., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Journal of Biological Chemistry. 296, 100360.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Enzymatic cross-linking of collagens in organ fibrosis - resolution and assessment
Pehrsson, M., Mortensen, J. H., Manon-Jensen, T., Bay-Jensen, A., Karsdal, M. A. & Davies, Michael J., 2021, In: Expert Review of Molecular Diagnostics. 21, 10, p. 1049-1064
Research output: Contribution to journal › Review › Research › peer-review
Published
M. jannaschii FtsZ, a key protein in bacterial cell division, is inactivated by peroxyl radical-mediated methionine oxidation
Reyes, J. S., Fuentes Lemus, Eduardo, Aspée, A., Davies, Michael J., Monasterio, O. & López-Alarcón, C., 2021, In: Free Radical Biology and Medicine. 166, p. 53-66
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols
Sauerland, M., Mertes, R., Morozzi, C., Eggler, A. L., Gamon, Luke Francis & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 169, p. 1-11 569.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Kinetic data for the reactions of alpha,beta-unsaturated aldehydes shed light on their molecular targets and biological effects
Sauerland, M., Gamon, Luke Francis & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 596 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
The role of RNA oxidation in islet dysfunction in Type 2 diabetes
Sileikaite, I., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1 , p. S37-S38
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Processed foods drive intestinal barrier permeability and microvascular diseases
Snelson, M., Tan, S. M., Clarke, R. E., De Pasquale, C., Thallas-Bonke, V., Nguyen, T. V., Penfold, S. A., Harcourt, B. E., Sourris, K. C., Lindblom, R. S., Ziemann, M., Steer, D., El-Osta, A., Davies, M. J., Donnellan, L., Deo, P., Kellow, N. J., Cooper, M. E., Woodruff, T. M., Mackay, C. R. & 2 others, Forbes, J. M. & Coughlan, M. T., 2021, In: Science Advances. 7, 14, eabe4841.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Suppressive effect of 1,4-anhydro-4-seleno-D-talitol (SeTal) on atopic dermatitis-like skin lesions in mice through regulation of inflammatory mediators
Voss, G. T., de Oliveira, R. L., Davies, Michael J., Domingues, W. B., Campos, V. F., Soares, M. P., Luchese, C., Schiesser, C. H. & Wilhelm, E. A., 2021, In: Journal of Trace Elements in Medicine and Biology. 67, 10 p., 126795.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chlorination and nitration of extracellular matrix by inflammatory myeloperoxidase-derived oxidants in the presence of nitrite
Xu, Shuqi, Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 566 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Dynein regulates Kv7.4 channel trafficking from the cell membrane
van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.
Research output: Contribution to journal › Journal article › Research › peer-review
2020
Published
Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination
Blossom, B. M., Russo, D. A., Singh, R. K., Van Oort, B., Keller, M. B., Simonsen, Tor Ivan, Perzon, A., Gamon, Luke Francis, Davies, Michael J., Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In: ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Scientific Reports. 13 p., 666.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Interaction kinetics of selenium -containing compounds with oxidants
Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael J., 2020, In: Free Radical Biology and Medicine. 155, p. 58-68
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidant-induced glutathionylation at protein disulfide bonds
Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael J., 20 Nov 2020, In: Free Radical Biology and Medicine. 160, p. 513-525 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease
Davies, Michael J. & Hawkins, Clare Louise, 2020, In: Antioxidants & Redox Signaling. 32, 13, p. 957-981
Research output: Contribution to journal › Review › Research › peer-review
Published
Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion
Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael J. & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks
Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael J. & Lopez-Alarcon, C., 2020, In: Free Radical Biology and Medicine. 152, p. 61-73
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization
Gamon, Luke Francis, Guo, C., He, Jianfei, Hägglund, Per Mårten, Hawkins, Clare Louise & Davies, Michael J., Sep 2020, In: Redox Biology. 36, 9 p., 101586.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase
Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael J., 2020, In: Redox Biology. 28, 12 p., 101331.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction
Gentile, C., Kesteven, S., Wu, J., Davies, Michael J., Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages
Guo, C., Sileikaite, I., Davies, Michael J. & Hawkins, Clare Louise, 2020, In: Antioxidants. 9, 12, 14 p., 1255.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
Guo, C., Davies, Michael J. & Hawkins, Clare Louise, Sep 2020, In: Redox Biology. 36, 14 p., 101666.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin
He, Jianfei, Becares, E. R., Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael J. & Hägglund, Per Mårten, 2020, In: Redox Biology. 36, 11 p., 101631.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation
Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael J. & Marciniak, B., 2020, In: Free Radical Biology and Medicine. 153, p. 12-16 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis
Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael J. & Siebuhr, A. S., 2020, In: Scientific Reports. 10, 1, 10 p., 17300.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols
Karimi, M., Crossett, B., Cordwell, S. J., Pattison, David & Davies, Michael J., 2020, In: Free Radical Biology and Medicine. 154, p. 62-74 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites
Leinisch, F., Mariotti, M., Andersen, S. H., Lindemose, Søren, Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael J., 2020, In: Scientific Reports. 10, 1, 11 p., 3106.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Azocompounds as generators of defined radical species: Contributions and challenges for free radical research
López-Alarcón, C., Fuentes-Lemus, E., Figueroa, J. D., Dorta, E., Schöneich, C. & Davies, Michael J., 2020, In: Free Radical Biology and Medicine. 160, p. 78-91
Research output: Contribution to journal › Review › Research › peer-review
Published
The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes
Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael J., Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In: Archives of Biochemistry and Biophysics. 689, 7 p., 108443.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone
Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael J., 2020, In: Redox Biology. 28, 9 p., 101335 .
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway
Shu, N., Hägglund, Per Mårten, Cai, H., Hawkins, Clare Louise & Davies, Michael J., Jan 2020, In: Redox Biology. 29, UNSP 101400.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN⁻)
Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Redox Biology. 36, 13 p., 101641.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings
Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael J., 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure
Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael J. & Lund, Marianne N., 2020, In: Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2019
Published
3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism
Avila, F., Ravello, N., Zanocco, A. L., Gamon, Luke Francis, Davies, Michael J. & Silva, E., 2019, In: Free Radical Biology and Medicine. 141, p. 103-114
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells
Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 134, p. 526-536
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines
Carroll, L., Karton, A., Radom, L., Davies, Michael J. & Pattison, D. I., 2019, In: Chemical Research in Toxicology. 32, 3, p. 513-525 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula
Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 68-81
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models
Chen, Z., Kondrashina, A., Greco, I., Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching
David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Redox Biology. 24, 9 p., 101207.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tempus fugit horizontal ellipsis
Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 1-1
Research output: Contribution to journal › Editorial › Research › peer-review
Published
1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule
Davies, Michael J. & Schiesser, C. H., 2019, In: New Journal of Chemistry. 43, 25, p. 9759-9765
Research output: Contribution to journal › Review › Research › peer-review
Published
Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]
Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]
Flouda, K., Davies, Michael J. & Hawkins, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan
Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 143, p. 375-386
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]
Gamon, Luke Francis & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]
Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Whey proteins: targets of oxidation, or mediators of redox protection
Giblin, L., Yalcin, A. S., Bicim, G., Kramer, A. C., Chen, Z., Callanan, M. J., Arranz, E. & Davies, Michael J., 2019, In: Free Radical Research. 53, S1, p. 1136–1152 17 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Detection, identification, and quantification of oxidative protein modifications
Hawkins, Clare Louise & Davies, Michael J., 2019, In: Journal of Biological Chemistry. 294, 51, p. 19683-19708
Research output: Contribution to journal › Review › Research › peer-review
Published
Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins: [Meeting Abstract]
Ignasiak-Kciuk, M., Shashikadze, B., Frackowiak, K., Gamon, Luke Francis, Davies, Michael J. & Marciniak, B., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S30-S30 89.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}
Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael J. & Siebuhr, A. S., 2019, In: Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin
Krämer, A. C. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications
Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 24, UNSP 101226.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Analysis of protein chlorination by mass spectrometry
Nybo, T., Davies, Michael J. & Rogowska-Wrzesinska, A., 2019, In: Redox Biology. 26, 10 p., UNSP 101236.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase
Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 20, p. 496-513
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]
Shu, N., Hägglund, Per Mårten & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S9-S9 8.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function: [Meeting Abstract]
Shu, N. & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S49-S49 168.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Reaction of quinones with proteins: Kinetics of adduct formation, effects on enzymatic activity and protein structure, and potential reversibility of modifications
Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 137, p. 169-180
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode
Silva, E., Barrias, P., Fuentes-Lemus, E., Tirapegui, C., Aspee, A., Carroll, L., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Free Radical Biology and Medicine. 131, p. 133-143
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Copper ion / H₂O₂ oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action
Tiwari, M. K., Hägglund, Per Mårten, Møller, I. M., Davies, Michael J. & Bjerrum, Morten Jannik, 2019, In: Redox Biology. 26, 15 p., 101262.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)
Tur, J. A., Jacob, C., Chaimbault, P., Tadayyon, M., Richling, E., Hermans, N., dos Santos, C. N., Diederich, M., Giblin, L., Elhabiri, M., Gaucher, C., Andreoletti, P., Fernandes, A., Davies, Michael J., Bartoszek, A. & Cherkaoui-Malki, M., 2019, In: Free Radical Research. 53, S1, p. 1163-1170
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function
Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 136, p. 118-134
Research output: Contribution to journal › Journal article › Research › peer-review
2018
Published
Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
Borges, E. L., Ignasiak, M. T., Velichenko, Y., Perin, G., Hutton, C. A., Davies, Michael J. & Schiesser, C. H., 25 Mar 2018, In: Chemical Communications. 54, 24, p. 2990-2993
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis: [Meeting Absract]
Cai, H., Chuang, Christine & Davies, Michael J., 2018, In: International Journal of Experimental Pathology. 99, 6, p. A24-A24
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Apr 2018, In: Free Radical Biology and Medicine. 118, p. 126-136
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula: [Meeting Abstract]
Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, Supplement 1, p. S47 1 p., P-8.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]
Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael J., 1 Feb 2018, In: Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent
Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael J. & Lopez-Alarcon, C., 1 Aug 2018, In: Food Chemistry. 256, p. 119-128
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Aggregation of alpha- and beta- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation
Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Escobar, E., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 20 Aug 2018, In: Free Radical Biology and Medicine. 124, p. 176-188
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]
Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Identification and characterization of protein cross-links induced by oxidative reactions
Hägglund, Per Mårten, Mariotti, M. & Davies, Michael J., 2018, In: Expert Review of Proteomics. 15, 8, p. 665-681
Research output: Contribution to journal › Review › Research › peer-review
Published
Mechanistic view of iodide in oxidative stress: [Meeting Abstract]
Kciuk, M. I., Davies, Michael J. & Marciniak, B., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S122-S122 P-254.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017)
Khramtsov, V. V. & Davies, Michael J., 2018, In: Free Radical Research. 52, 3, p. 305-306
Research output: Contribution to journal › Editorial › Research
Published
Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals
Leinisch, F., Mariotti, M., Hägglund, Per Mårten & Davies, Michael J., Oct 2018, In: Free Radical Biology and Medicine. 126, p. 73-86
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Nitration alters laminin polymerization: [Meeting Abstract]
Lorentzen, Lasse Gøbel & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S127-S127 P-271.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation
Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, Michael J. & Hägglund, Per Mårten, 2018, In: Journal of Proteome Research. 17, 6, p. 2017-2027
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin
Nielsen, L. R., Lund, Marianne N., Davies, Michael J., Nielsen, J. H. & Nielsen, S. B., 2018, In: International Dairy Journal. 79, p. 52-61 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Analysis of extracellular matrix protein chlorination and oxidation by mass spectrometry: [Meeting Abstract]
Nybo, T., Davies, Michael J. & Rogowska-Wrzesinska, A., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S56-S57 P-40.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function
Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., Oct 2018, In: Redox Biology. 19, p. 388-400
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function: [Meeting Abstract]
Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., 2018, In: Free Radical Biology & Medicine. 120, S1, p. S24-S24 P-41 .
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Cardiac spheroid co-cultures as a novel in vitro model to study human heart microenvironment
Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Davies, Michael J., Figtree, G. & Gentile, C., 2018, In: Journal of Pharmacological and Toxicological Methods. 93, p. 167 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Kinetics and biological consequences of quinone-induced protein adduction: [Meeting Abstract]
Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S55-S55 P-34.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Influence of O-2 on riboflavin-mediated photo-oxidation of lysozyme: [Meeting Abstract]
Silva, E., Tirapegui, C., Fuentes-Lemus, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Caroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S58-S59 P-46.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Early events in copper-ion catalyzed oxidation of α-synuclein
Tiwari, M. K., Leinisch, F., Sahin, C., Møller, I. M., Otzen, D. E., Davies, Michael J. & Bjerrum, Morten Jannik, 2018, In: Free Radical Biology & Medicine. 121, p. 38-50 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]
Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael J., 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
2017
Published
Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael J. & Hawkins, Clare Louise, 2017, In: Redox Biology. 12, p. 872-882 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 132-142 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins
Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 395-405 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peroxides and protein oxidation
Davies, Michael J., 1 Jan 2017, Hydrogen Peroxide Metabolism in Health and Disease. CRC Press, p. 101-124
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function
Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael J. & López-Alarcón, C., Nov 2017, In: Free Radical Biology and Medicine. 112, p. 60-68 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification
Forman, H. J., Davies, Michael J., Krämer, A. C., Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In: Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma
Havelund, J. F., Wojdyla, K. I., Davies, Michael J., Jensen, O. N., Møller, I. M. & Rogowska-Wrzesinska, A., 6 Mar 2017, In: Journal of Proteomics. 156, p. 40-51 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function
Indo, H. P., Hawkins, Clare Louise, Nakanishi, I., Matsumoto, K., Matsui, H., Suenaga, S., Davies, Michael J., St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Vol. 240. p. 439-456 18 p. (Handbook of Experimental Pharmacology, Vol. 240).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1
Kovacevic, Z., Sahni, S., Lok, K. H., Davies, Michael J., Wink, D. A. & Richardson, D. R., May 2017, In: B B A - Reviews on Cancer. 1861, 5 Pt A, p. 995-999 5 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin
Krämer, A. C., Torreggiani, A. & Davies, Michael J., 2017, In: Journal of Agricultural and Food Chemistry. 65, 47, p. 10258-10269 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues
Leinisch, F., Mariotti, M., Rykaer, M., López-Alarcón, C., Hägglund, Per Mårten & Davies, Michael J., Nov 2017, In: Free Radical Biology & Medicine. 112, p. 240-252 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The immunoproteasome is induced by cytokines and regulates apoptosis in human islets
Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael J., Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
1,4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress
Ng, H. H., Leo, C. H., O'Sullivan, K., Alexander, S., Davies, Michael J., Schiesser, C. H. & Parry, L. J., Mar 2017, In: Biochemical Pharmacology. 128, p. 34-45 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cardiac spheroids as promising in vitro models to study the human heart microenvironment
Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Figtree, G. A., Davies, Michael J. & Gentile, C., 1 Aug 2017, In: Scientific Reports. 7, 12 p., 7005.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications
Rykær, M., Svensson, B., Davies, Michael J. & Hägglund, Per Mårten, 3 Nov 2017, In: Journal of Proteome Research. 16, 11, p. 3978-3988 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage
Skjoldager, N., Blanner Bang, M., Rykaer, M., Björnberg, O., Davies, Michael J., Svensson, B., Harris, P. & Hägglund, Per Mårten, Apr 2017, In: Scientific Reports. 7, 10 p., 46282.
Research output: Contribution to journal › Journal article › Research › peer-review
2016
Published
The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues
Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael J., 1 Jan 2016, In: Free Radical Biology & Medicine. 90, p. 195-205 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods
Davies, Michael J., 2016, In: Methods. 109, p. 21-30 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Protein oxidation and peroxidation
Davies, Michael J., 2016, In: Biochemical Journal. 473, 7, p. 805-825 21 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Peroxynitrite-mediated oxidation of plasma fibronectin
Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael J., Aug 2016, In: Free Radical Biology & Medicine. 97, p. 602-615 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals
Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael J. & Lopez-Alarcon, C., 2016, In: RSC Advances. 6, 63, p. 57948-57955 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space
Indo, H. P., Majima, H. J., Terada, M., Suenaga, S., Tomita, K., Yamada, S., Higashibata, A., Ishioka, N., Kanekura, T., Nonaka, I., Hawkins, Clare Louise, Davies, Michael J., Clair, D. K. S. & Mukai, C., 16 Dec 2016, In: Scientific Reports. 6, 10 p., 39015.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?
Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael J. & Hawkins, Clare Louise, 2016, In: P L o S One. 11, 12, 16 p., e0168844.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Competitive kinetics as a tool to determine rate constants for reduction of ferrylmyoglobin by food components
Jongberg, S., Lund, Marianne N., Pattison, David, Skibsted, Leif Horsfelt & Davies, Michael J., 2016, In: Food Chemistry. 199, p. 36-41 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability
Karimi, M., Ignasiak, M. T., Chan, B., Croft, A. K., Radom, L., Schiesser, C. H., Pattison, D. I. & Davies, Michael J., 12 Dec 2016, In: Scientific Reports. 6, 12 p., 38572.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Key role of cysteine residues and sulfenic acids in thermal- and H₂O₂-mediated modification of β-lactoglobulin
Krämer, A. C., Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael J., 2016, In: Free Radical Biology & Medicine. 97, 8, p. 544–555 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Key role of cysteine residues in thermal- and H2O2-mediated modification of beta-lactoglobulin
Krämer, A. C., Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael J., 2016, In: Free Radical Biology & Medicine. 96, Suppl. 1, p. S16 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease
Leung, C., Herath, C. B., Jia, Z., Andrikopoulos, S., Brown, B. E., Davies, Michael J., Rivera, L. R., Furness, J. B., Forbes, J. M. & Angus, P. W., 21 Sep 2016, In: World Journal of Gastroenterology. 22, 35, p. 8026-8040 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Quinone-induced protein modifications: kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins
Li, Y., Jongberg, S., Andersen, Mogens Larsen, Davies, Michael J. & Lund, Marianne N., 2016, In: Free Radical Biology & Medicine. 97, p. 148-157 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages
Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, Michael J. & Hawkins, Clare Louise, 2016, In: Free Radical Biology & Medicine. 94, p. 88-98 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chasing Great Paths of Helmut “Oxidative Stress” Sies
Majima, H., Indo, H., Nakanishi, I., Suenaga, S., Matsumoto, K., Matsui, H., Minamiyami, Y., Ichikawa, H., Yen, H., Hawkins, C., Davies, Michael J., Ozawa, T. & St. Clair, D., 2016, In: Archives of Biochemistry and Biophysics. 595, p. 54-60 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells
Talib, J. & Davies, Michael J., 2016, In: Journal of Biological Inorganic Chemistry. 21, 3, p. 305-317 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development
Tweeddale, H. J., Hawkins, Clare Louise, Janmie, J. F., Truscott, R. J. W. & Davies, Michael J., Oct 2016, In: Free Radical Research. 50, 10, p. 1116-1130 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Special issue for the 7th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia 2015 Thailand)
Ungsurungsie, M., Surh, Y., Toyokuni, S. & Davies, Michael J., 2 Oct 2016, In: Free Radical Research. 50, 10, p. 1045-1046
Research output: Contribution to journal › Editorial › Research
2015
Published
Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants
Carroll, L., Davies, Michael J. & Pattison, D. I., 2015, In: Free Radical Research. 49, 6, p. 750-767 18 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael J. & Hawkins, Clare Louise, Jul 2015, In: Free Radical Biology & Medicine. 84, p. 279-288 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Sulfur and selenium in oxidation protection
Davies, Michael J., 2015, In: La chimica e l’industria, Chimica & Materiali. 2015, 6, p. 50-54
Research output: Contribution to journal › Review › Research › peer-review
Published
Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin
Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael J., Dec 2015, In: Free Radical Biology & Medicine. 89, p. 721-733 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences
Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael J. & Spickett, C. M., Apr 2015, In: Free Radical Research. 49, 4, p. 347-73 27 p.
Research output: Contribution to journal › Review › Research › peer-review
Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion
Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael J., Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In: Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): implications for foam cell formation in atherosclerosis
Ismael, F. O., Proudfoot, J. M., Brown, B. E., van Reyk, D. M., Croft, K. D., Davies, Michael J. & Hawkins, C. L., May 2015, In: Archives of Biochemistry and Biophysics. 573, p. 40-51 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice
Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael J., May 2015, In: Atherosclerosis. 240, 1, p. 234-241 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation
Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, Michael J., Beattie, J. H. & Galley, H. F., 2015, In: British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase
Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael J., 27 Mar 2015, In: Free Radical Research. 49, 6, p. 743-9 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Kinetics of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance
Storkey, C., Pattison, D. I., Ignasiak, M. T., Schiesser, C. H. & Davies, Michael J., Dec 2015, In: Free Radical Biology & Medicine. 89, p. 1049-1056 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Prevention of degradation of the natural high potency sweetener (2R,4R)-monatin in mock beverage solutions
Storkey, C., Pattison, David, Koehler, J. A., Gaspard, D. S., Evans, J. C., Hagestuen, E. D. & Davies, Michael J., 2015, In: Food Chemistry. 173, p. 645-651
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Bio-Activation of Polyether Ether Ketone Using Plasma Immersion Ion Implantation: A Kinetic Model
Wakelin, E. A., Kondyurin, A. V., Wise, S. G., McKenzie, D. R., Davies, Michael J. & Bilek, M. M. M., 2015, In: Plasma Processes and Polymers.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Temperature Activated Diffusion of Radicals through Ion Implanted Polymers
Wakelin, E. A., Davies, Michael J., Bilek, M. M. M. & McKenzie, D. R., 2 Dec 2015, In: A C S Applied Materials and Interfaces. 7, 47, p. 26340-26345 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions
Weber, D., Davies, Michael J. & Grune, T., 1 Aug 2015, In: Redox Biology. 5, p. 367-380 14 p.
Research output: Contribution to journal › Review › Research › peer-review
2014
Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants
Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael J., Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In: Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice
Brown, B. E., Kim, C. H. J., Torpy, F. R., Bursill, C. A., McRobb, L. S., Heather, A. K., Davies, Michael J. & van Reyk, D. M., Feb 2014, In: Atherosclerosis. 232, 2, p. 403-9 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Increasing capacity to deliver diabetes self-management education: Results of the DESMOND lay educator non-randomized controlled equivalence trial
Carey, M. E., Mandalia, P. K., Daly, H., Gray, L. J., Hale, R., Martin Stacey, L., Taub, N., Skinner, Timothy, Stone, M., Heller, S., Khunti, K. & Davies, Michael J., 1 Jan 2014, In: Diabetic Medicine. 31, 11, p. 1431-1438 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation and modification of extracellular matrix and its role in disease
Chuang, Christine, Degendorfer, G. & Davies, Michael J., Sep 2014, In: Free Radical Research. 48, 9, p. 970-89 20 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells
Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael J., 15 Apr 2014, In: Biochemical Journal. 459, 2, p. 313-22 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis
Dunn, L. L., Simpson, P. J. L., Prosser, H. C., Lecce, L., Yuen, G. S. C., Buckle, A., Sieveking, D. P., Vanags, L. Z., Lim, P. R., Chow, R. W. Y., Lam, Y. T., Clayton, Z., Bao, S., Davies, Michael J., Stadler, N., Celermajer, D. S., Stocker, R., Bursill, C. A., Cooke, J. P. & Ng, M. K. C., Feb 2014, In: Diabetes. 63, 2, p. 675-87 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses
Gad, N. A., Mizdrak, J., Pattison, D. I., Davies, Michael J., Truscott, R. J. W. & Jamie, J. F., Feb 2014, In: Investigative Ophthalmology & Visual Science. 55, 2, p. 849-55 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction
Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael J., Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A Novel Method for Isolating and Culturing Human Cardiomyocytes from Cryopreserved Tissues
Gentile, C., Kuehn, B., Davies, Michael J. & dos Remedios, C. G., 2014, In: Biophysical Journal.
Research output: Contribution to journal › Journal article › Research › peer-review
Detection and characterisation of radicals in biological materials using EPR methodology
Hawkins, Clare Louise & Davies, Michael J., Feb 2014, In: B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Competitive reduction of perferrylmyoglobin radicals by protein thiols and plant phenols
Jongberg, S., Lund, Marianne N., Skibsted, Leif Horsfelt & Davies, Michael J., 2014, In: Journal of Agricultural and Food Chemistry. 62, 46, p. 11279-11288 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides
Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, Clare Louise & Davies, Michael J., May 2014, In: Free Radical Biology & Medicine. 70, p. 96-105 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael J., Iozzo, R. V. & Whitelock, J. M., Apr 2014, In: Matrix Biology. 35, p. 112-22 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal
Morgan, P. E., Sheahan, P. J. & Davies, Michael J., 2014, In: PloS one. 9, 1, 11 p., e86564.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction
Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael J., Oct 2014, In: Free Radical Research. 48, 10, p. 1256-66 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
MODULATION OF ENDOTHELIAL CELL FUNCTION BY THE MYELOPEROXIDASE-DERIVED OXIDANT HYPOCHLOROUS ACID (HOCl) AND ITS CONTRIBUTION TO ATHEROSCLEROSIS
Rayner, B. S., Lloyd, M. M., Summers, F. A., Davies, Michael J. & Hawkins, Clare Louise, 2014, In: Hypertension.
Research output: Contribution to journal › Journal article › Research › peer-review
Mechanisms of degradation of the natural high-potency sweetener (2R,4R)-monatin in mock beverage solutions
Storkey, C., Pattison, D. I., Gaspard, D. S., Hagestuen, E. D. & Davies, Michael J., 16 Apr 2014, In: Journal of Agricultural and Food Chemistry. 62, 15, p. 3476-87 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach
Storkey, C., Davies, Michael J. & Pattison, D. I., Aug 2014, In: Free Radical Biology & Medicine. 73, p. 60-6 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction
Talib, J., Kwan, J., Suryo Rahmanto, A., Witting, P. K. & Davies, Michael J., 1 Jan 2014, In: Biochemical Journal. 457, 1, p. 89-97 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2013
Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals: role of oxidizable amino acid residues
Arenas, A., López-Alarcón, C., Kogan, M., Lissi, E., Davies, Michael J. & Silva, E., 18 Jan 2013, In: Chemical Research in Toxicology. 26, 1, p. 67-77 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages
Brown, B. E., Nobecourt, E., Zeng, J., Jenkins, A. J., Rye, K. & Davies, Michael J., 2013, In: PLOS ONE. 8, 5, p. e65430
Research output: Contribution to journal › Journal article › Research › peer-review
The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
Graham, G. G., Davies, Michael J., Day, R. O., Mohamudally, A. & Scott, K. F., Jun 2013, In: Inflammopharmacology. 21, 3, p. 201-32 32 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)
Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K., Davies, Michael J. & Hawkins, Clare Louise, 15 Jan 2013, In: Biochemical Journal. 449, 2, p. 531-42 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Biomarkers of oxidative stress study V: ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine
Kadiiska, M. B., Basu, S., Brot, N., Cooper, C., Saari Csallany, A., Davies, Michael J., George, M. M., Murray, D. M., Jackson Roberts, L., Shigenaga, M. K., Sohal, R. S., Stocker, R., Van Thiel, D. H., Wiswedel, I., Hatch, G. E. & Mason, R. P., Aug 2013, In: Free Radical Biology & Medicine. 61, p. 408-15 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells
Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael J. & Hawkins, Clare Louise, Dec 2013, In: Free Radical Biology & Medicine. 65, p. 1352-62 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes
Morgan, P. E., Sheahan, P. J., Pattison, D. I. & Davies, Michael J., Aug 2013, In: Free Radical Biology & Medicine. 61, p. 229-42 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content
Thallas-Bonke, V., Coughlan, M. T., Tan, A. L., Harcourt, B. E., Morgan, P. E., Davies, Michael J., Bach, L. A., Cooper, M. E. & Forbes, J. M., Jan 2013, In: Nephrology. 18, 1, p. 47-56 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Superoxide radicals have a protective role during H2O2 stress
Thorpe, G. W., Reodica, M., Davies, Michael J., Heeren, G., Jarolim, S., Pillay, B., Breitenbach, M., Higgins, V. J. & Dawes, I. W., Sep 2013, In: Molecular Biology of the Cell. 24, 18, p. 2876-84 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2012
Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates
Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, Michael J. & Hawkins, Clare Louise, 15 Mar 2012, In: Free Radical Biology & Medicine. 52, 6, p. 1075-85 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells
Cook, N. L., Viola, H. M., Sharov, V. S., Hool, L. C., Schöneich, C. & Davies, Michael J., 1 Mar 2012, In: Free Radical Biology & Medicine. 52, 5, p. 951-61 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins
Cook, N. L., Pattison, D. I. & Davies, Michael J., 1 Dec 2012, In: Free Radical Biology & Medicine. 53, 11, p. 2072-80 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-Derived Oxidants Rapidly and Efficiently Oxidise Protein Zinc-Thiol Clusters
Cook, N. L., Pattison, David & Davies, Michael J., 2012, In: Free Radical Biology and Medicine. 53, Supl. 2, p. S146 1 p., 355.
Research output: Contribution to journal › Conference abstract in journal › Research
Free Radical Research origins
Davies, Michael J., Jan 2012, In: Free Radical Research. 46, 1, p. 1
Research output: Contribution to journal › Journal article › Research
Computational design of effective, bioinspired HOCl antioxidants: the role of intramolecular Cl+ and H+ shifts
Karton, A., O'Reilly, R. J., Pattison, D. I., Davies, Michael J. & Radom, L., 21 Nov 2012, In: Journal of the American Chemical Society. 134, 46, p. 19240-5 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care
Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael J., 9 Jun 2012, In: BMJ (Online). 344, 7860, e2333.
Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis
Moheimani, F., Kim, C. H. J., Rahmanto, A. S., van Reyk, D. M. & Davies, Michael J., Jul 2012, In: Atherosclerosis. 223, 1, p. 144-51 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline
Morgan, P. E., Pattison, D. I. & Davies, Michael J., 15 Jan 2012, In: Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Photo-oxidation of proteins
Pattison, D. I., Rahmanto, A. S. & Davies, Michael J., Jan 2012, In: Photochemical & Photobiological Sciences. 11, 1, p. 38-53 16 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids
Pattison, D. I., Davies, Michael J. & Hawkins, Clare Louise, Aug 2012, In: Free Radical Research. 46, 8, p. 975-95 21 p.
Research output: Contribution to journal › Journal article › Research › peer-review
The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies
Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael J., 1 Nov 2012, In: Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Selenium-containing amino acids as direct and indirect antioxidants
Rahmanto, A. S. & Davies, Michael J., Nov 2012, In: I U B M B Life. 64, 11, p. 863-71 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage
Skaff, O., Pattison, D. I., Morgan, P. E., Bachana, R., Jain, V. K., Priyadarsini, K. I. & Davies, Michael J., 1 Jan 2012, In: Biochemical Journal. 441, 1, p. 305-16 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Reduced metal ion concentrations in atherosclerotic plaques from subjects with type 2 diabetes mellitus
Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., Croft, K. D., Mori, T. A., Vacata, V., Daemen, M. J. A. P., Waltenberger, J. & Davies, Michael J., Jun 2012, In: Atherosclerosis. 222, 2, p. 512-8 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Preventing protein oxidation with sugars: scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives
Storkey, C., Pattison, D. I., White, J. M., Schiesser, C. H. & Davies, Michael J., 19 Nov 2012, In: Chemical Research in Toxicology. 25, 11, p. 2589-99 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Photo-oxidation-induced inactivation of the selenium-containing protective enzymes thioredoxin reductase and glutathione peroxidase
Suryo Rahmanto, A., Pattison, D. I. & Davies, Michael J., 15 Sep 2012, In: Free Radical Biology & Medicine. 53, 6, p. 1308-16 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine
Talib, J., Pattison, D. I., Harmer, J. A., Celermajer, D. S. & Davies, Michael J., 1 Jul 2012, In: Free Radical Biology & Medicine. 53, 1, p. 20-9 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Truscott, R. J. W., Mizdrak, J., Friedrich, M. G., Hooi, M. Y., Lyons, B., Jamie, J. F., Davies, Michael J., Wilmarth, P. A. & David, L. L., Jun 2012, In: Experimental Eye Research. 99, p. 48-54 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2011
Published
The association between anxiety and measures of glycaemia in a population-based diabetes screening programme
Aujla, N., Davies, Michael J., Skinner, Timothy, Gray, L. J., Webb, D. R., Srinivasan, B. & Khunti, K., 1 Jul 2011, In: Diabetic Medicine. 28, 7, p. 785-788 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study
Crasto, W., Jarvis, J., Khunti, K., Skinner, Timothy, Gray, L. J., Brela, J., Troughton, J., Daly, H., Lawrence, I. G., McNally, P. G., Carey, M. E. & Davies, Michael J., 1 Sep 2011, In: Diabetes Research and Clinical Practice. 93, 3, p. 328-336 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation
Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael J., 27 Jul 2011, In: Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention
Davies, Michael J., Jan 2011, In: Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 8-19 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome
Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael J., 15 Jan 2011, In: Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Mechanisms and consequences of oxidative damage to extracellular matrix
Kennett, E. C., Chuang, Christine, Degendorfer, G., Whitelock, J. M. & Davies, Michael J., Oct 2011, In: Biochemical Society Transactions. 39, 5, p. 1279-87 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima
Mai, K., Smith, N. C., Feng, Z., Katrib, M., Slapeta, J., Slapetova, I., Wallach, M. G., Luxford, C., Davies, Michael J., Zhang, X., Norton, R. S. & Belli, S. I., Sep 2011, In: International Journal for Parasitology (Online). 41, 11, p. 1157-64 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins
Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael J., 2011, In: Journal of Diabetes Research. 2011, p. 851280
Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase
Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
One-electron reduction of N-chlorinated and N-brominated species is a source of radicals and bromine atom formation
Pattison, D. I., O'Reilly, R. J., Skaff, O., Radom, L., Anderson, R. F. & Davies, Michael J., 21 Mar 2011, In: Chemical Research in Toxicology. 24, 3, p. 371-82 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial
Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Dalyb, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Olivere, L., 1 Mar 2011, In: Psychology and Health. 26, 3, p. 321-335 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis and antioxidant capacity of 5-selenopyranose derivatives
Storkey, C., Davies, Michael J., White, J. M. & Schiesser, C. H., 14 Sep 2011, In: Chemical communications (Cambridge, England). 47, 34, p. 9693-5 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Catalytic activity of selenomethionine in removing amino acid, peptide, and protein hydroperoxides
Suryo Rahmanto, A. & Davies, Michael J., 15 Dec 2011, In: Free Radical Biology & Medicine. 51, 12, p. 2288-99 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2010
Published
Ethnic differences in the prevalence and recognition of depression in a primary care population with and without type 2 diabetes
Ali, S., Taub, N. A., Stone, M. A., Davies, Michael J., Skinner, Timothy & Khunti, K., 1 Sep 2010, Diabetologia.
Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Published
The association between depression and health-related quality of life in people with type 2 diabetes: A systematic literature review
Ali, S., Stone, M., Skinner, Timothy, Robertson, N., Davies, Michael J. & Khunti, K., 1 Feb 2010, In: Diabetes/Metabolism Research and Reviews. 26, 2, p. 75-89 15 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: A comparison of two screening tools
Aujla, N., Skinner, Timothy, Khunti, K. & Davies, Michael J., 1 Aug 2010, In: Diabetic Medicine. 27, 8, p. 896-905 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cost effectiveness analysis
Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M. E., Campbell, M. J., Heller, S., Khunti, K., Skinner, Timothy & Davies, Michael J., 26 Aug 2010, In: BMJ (Online). 341, 7770, c4093.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: A cross-sectional study
Gray, L. J., Tringham, J. R., Davies, Michael J., Webb, D. R., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Dec 2010, In: Vascular Health and Risk Management. 6, 1, p. 837-842 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains
Kennett, E. C., Rees, M. D., Malle, E., Hammer, A., Whitelock, J. M. & Davies, Michael J., 15 Jul 2010, In: Free Radical Biology & Medicine. 49, 2, p. 282-93 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study
Khunti, K., Taub, N., Tringham, J., Jarvis, J., Farooqi, A., Skinner, Timothy & Davies, Michael J., 1 Apr 2010, In: Primary Care Diabetes. 4, 1, p. 25-32 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations
Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 15 Apr 2010, In: Biochemical Pharmacology. 79, 8, p. 1156-64 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages
Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael J., 15 Aug 2010, In: Biochemical Journal. 430, 1, p. 161-9 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis
Moheimani, F., Morgan, P. E., van Reyk, D. M. & Davies, Michael J., Jun 2010, In: B B A - Reviews on Cancer. 1802, 6, p. 561-71 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I
Nobécourt, E., Tabet, F., Lambert, G., Puranik, R., Bao, S., Yan, L., Davies, Michael J., Brown, B. E., Jenkins, A. J., Dusting, G. J., Bonnet, D. J., Curtiss, L. K., Barter, P. J. & Rye, K., Apr 2010, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 766-72 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3
Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, Michael J. & Winterbourn, C. C., 1 Dec 2010, In: Biochemical Journal. 432, 2, p. 313-21 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Cellular effects of peptide and protein hydroperoxides
Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 15 Apr 2010, In: Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts
Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 30 Nov 2010, In: Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan
Rees, M. D., Whitelock, J. M., Malle, E., Chuang, Christine, Iozzo, R. V., Nilasaroya, A. & Davies, Michael J., Jan 2010, In: Matrix Biology. 29, 1, p. 63-73 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Depressive symptoms in the first year from diagnosis of Type 2 diabetes: Results from the DESMOND trial
Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Aug 2010, In: Diabetic Medicine. 27, 8, p. 965-967 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy
Sourris, K. C., Harcourt, B. E., Penfold, S. A., Yap, F. Y. T., Morley, A. L., Morgan, P. E., Davies, Michael J., Baker, S. T., Jerums, G. & Forbes, J. M., 2010, In: Journal of Diabetes Research. 2010, p. 974681
Research output: Contribution to journal › Journal article › Research › peer-review
Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction
Szuchman-Sapir, A. J., Pattison, D. I., Davies, Michael J. & Witting, P. K., 1 Jan 2010, In: Free Radical Biology & Medicine. 48, 1, p. 35-46 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2009
Published
The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus
Aujla, N., Abrams, K. R., Davies, Michael J., Taub, N., Skinner, Timothy & Khunti, K., 9 Nov 2009, In: PLoS ONE. 4, 11, e7755.
Research output: Contribution to journal › Journal article › Research › peer-review
Hypobromous acid and bromamine production by neutrophils and modulation by superoxide
Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael J., 1 Feb 2009, In: Biochemical Journal. 417, 3, p. 773-81 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products
Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael J., 1 Jul 2009, In: Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of protein modification by oxidants
Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael J., 15 Apr 2009, In: Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation
Kennett, E. C. & Davies, Michael J., 15 Aug 2009, In: Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients
Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Feb 2009, In: Free Radical Research. 43, 2, p. 117-27 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., May 2009, In: Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides
Rees, M. D., Bottle, S. E., Fairfull-Smith, K. E., Malle, E., Whitelock, J. M. & Davies, Michael J., 1 Jul 2009, In: Biochemical Journal. 421, 1, p. 79-86 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance
Skaff, O., Pattison, D. I. & Davies, Michael J., 15 Aug 2009, In: Biochemical Journal. 422, 1, p. 111-7 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2008
Published
Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial
Davies, Michael J., Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In: BMJ. 336, 7642, p. 491-495 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The DESMOND educational intervention
Davies, Michael J., Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In: Chronic Illness. 4, 1, p. 38-40 3 p.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Mammalian heme peroxidases: from molecular mechanisms to health implications
Davies, Michael J., Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In: Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation
Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael J., 15 Dec 2008, In: Biochemical Journal. 416, 3, p. 441-52 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid
Kennett, E. C. & Davies, Michael J., 1 Sep 2008, In: Free Radical Biology & Medicine. 45, 5, p. 716-25 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes: Baseline data from the DESMOND randomized controlled trial
Khunti, K., Skinner, Timothy, Heller, S., Carey, M. E., Dallosso, H. M. & Davies, Michael J., 1 Dec 2008, In: Diabetic Medicine. 25, 12, p. 1454-1461 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals
Lam, M. A., Pattison, D. I., Bottle, S. E., Keddie, D. J. & Davies, Michael J., Nov 2008, In: Chemical Research in Toxicology. 21, 11, p. 2111-9 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links
Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael J., 2008, In: Biochemical Journal. 410, 3, p. 565-574
Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid
Lloyd, M. M., van Reyk, D. M., Davies, Michael J. & Hawkins, Clare Louise, 1 Sep 2008, In: Biochemical Journal. 414, 2, p. 271-80 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage
Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael J., 15 Mar 2008, In: Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins
Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2008, In: Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I
Nobecourt, E., Zeng, J., Davies, Michael J., Brown, B. E., Yadav, S., Barter, P. J. & Rye, K. -., Jun 2008, In: Diabetologia. 51, 6, p. 1008-1017 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Oxidative damage to extracellular matrix and its role in human pathologies
Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael J., 15 Jun 2008, In: Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.
Research output: Contribution to journal › Journal article › Research › peer-review
The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study
Skaff, O., Pattison, D. I. & Davies, Michael J., 5 Aug 2008, In: Biochemistry. 47, 31, p. 8237-45 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
'Educator talk' and patient change: Some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial
Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Sep 2008, In: Diabetic Medicine. 25, 9, p. 1117-1120 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation
Stadler, N., Stanley, N., Heeneman, S., Vacata, V., Daemen, M. J. A. P., Bannon, P. G., Waltenberger, J. & Davies, Michael J., May 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 1024-30 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines
Summers, F. A., Morgan, P. E., Davies, Michael J. & Hawkins, Clare Louise, Sep 2008, In: Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin
Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael J. & Witting, P. K., 15 Sep 2008, In: Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study
Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael J., 1 Jul 2008, In: Patient Education and Counseling. 72, 1, p. 88-93 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2007
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael J., Mar 2007, In: F E B S Journal. 274, 6, p. 1530-41 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides
Dremina, E. S., Sharov, V. S., Davies, Michael J. & Schöneich, C., Oct 2007, In: Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products
Gracanin, M. & Davies, Michael J., 15 May 2007, In: Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism
Kennett, E. C. & Davies, Michael J., 15 Apr 2007, In: Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis
Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael J., Dec 2007, In: Free Radical Research. 41, 12, p. 1301-12 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin: cholesterol acyltransferase
Nobecourt, E., Davies, Michael J., Brown, B. E., Curtiss, L. K., Bonnet, D. J., Charlton, F., Januszewski, A. S., Jenkins, A. J., Barter, P. J. & Rye, K. -., Mar 2007, In: Diabetologia. 50, 3, p. 643-653 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses
Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., Aug 2007, In: Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 28 Aug 2007, In: Biochemistry. 46, 34, p. 9853-64 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro
Rashid, I., van Reyk, D. M. & Davies, Michael J., 6 Mar 2007, In: FEBS Letters. 581, 5, p. 1067-70 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of extracellular matrix and its components by hypobromous acid
Rees, M. D., McNiven, T. N. & Davies, Michael J., 15 Jan 2007, In: Biochemical Journal. 401, 2, p. 587-96 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants
Skaff, O., Pattison, D. I. & Davies, Michael J., Dec 2007, In: Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2006
Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides
Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Feb 2006, In: Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides
Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid
Malle, E., Marsche, G., Arnhold, J. & Davies, Michael J., Apr 2006, In: B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Reactions of myeloperoxidase-derived oxidants with biological substrates: Gaining chemical insight into human inflammatory diseases
Pattison, David & Davies, Michael J., 2006, In: Current Medicinal Chemistry. 13, 27, p. 3271-3290 20 p.
Research output: Contribution to journal › Review › Research › peer-review
Actions of ultraviolet light on cellular structures
Pattison, D. I. & Davies, Michael J., 2006, In: E X S. 96, p. 131-57 27 p.
Research output: Contribution to journal › Journal article › Research
Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage
Pattison, D. I. & Davies, Michael J., 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives
Rees, M. D. & Davies, Michael J., 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study
Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In: Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions
Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals
Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael J. & Radom, L., 31 Aug 2006, In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols
Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael J., 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions
Zeng, J. & Davies, Michael J., Dec 2006, In: Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2005
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers
Birinyi-Strachan, L. C., Davies, Michael J., Lewis, R. J. & Nicholson, G. M., Oct 2005, In: Neuropharmacology. 49, 5, p. 669-86 18 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells
Brown, B. E., Dean, R. T. & Davies, Michael J., Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
The oxidative environment and protein damage
Davies, Michael J., 17 Jan 2005, In: B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Guanine-specific DNA damage induced by gamma-irradiated histone
Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael J. & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function
Hawkins, Clare Louise & Davies, Michael J., Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael J., Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael J., 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The illness beliefs of people newly diagnosed with type 2 diabetes: results from the DESMOND pilot study
Heller, S., Davies, Michael J., Khunti, K., Skinner, Timothy & James, P., 1 Jan 2005, Diabetologia.
Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus
Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation
Pattison, D. I. & Davies, Michael J., 17 May 2005, In: Biochemistry. 44, 19, p. 7378-87 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation
Rees, M. D., Pattison, D. I. & Davies, Michael J., 1 Oct 2005, In: Biochemical Journal. 391, Pt 1, p. 125-34 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Protein oxidation injury occurs during pediatric cardiopulmonary bypass
Sheil, M. L., Luxford, C., Davies, Michael J., Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In: Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Diabetes screening anxiety and beliefs
Skinner, Timothy, Davies, Michael J., Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In: Diabetic Medicine. 22, 11, p. 1497-1502 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Utility of risk factors when screening for diabetes mellitus
Tringham, J. R., Davies, Michael J., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Jan 2005, Diabetes.
Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins
Zeng, J. & Davies, Michael J., Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2004
Published
EPR spin trapping of protein radicals
Davies, Michael J. & Hawkins, Clare Louise, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Reactive species formed on proteins exposed to singlet oxygen
Davies, Michael J., Jan 2004, In: Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products
Headlam, H. A. & Davies, Michael J., 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Protective mechanisms against peptide and protein peroxides generated by singlet oxygen
Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Feb 2004, In: Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Protein-bound kynurenine is a photosensitizer of oxidative damage
Parker, N. R., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., 1 Nov 2004, In: Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress
Pattison, D. I. & Davies, Michael J., 27 Apr 2004, In: Biochemistry. 43, 16, p. 4799-809 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates
Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper
Stadler, N., Lindner, R. A. & Davies, Michael J., 2004, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides
Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 241-8 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2003
Published
Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima
Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael J. & Smith, N. C., Jun 2003, In: Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Singlet oxygen-mediated damage to proteins and its consequences
Davies, Michael J., 6 Jun 2003, In: Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Radical chemistry of epigallocatechin gallate and its relevance to protein damage
Hagerman, A. E., Dean, R. T. & Davies, Michael J., 1 Jun 2003, In: Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite-induced oxidation of amino acids, peptides and proteins
Hawkins, C. L., Pattison, D. I. & Davies, Michael J., Dec 2003, In: Amino Acids. 25, 3-4, p. 259-74 16 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals
Headlam, H. A. & Davies, Michael J., 1 Jan 2003, In: Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles
Knott, H. M., Brown, B. E., Davies, Michael J. & Dean, R. T., Sep 2003, In: European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation
Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques
Woods, A. A., Linton, S. M. & Davies, Michael J., 1 Mar 2003, In: Biochemical Journal. 370, Pt 2, p. 729-35 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Fragmentation of extracellular matrix by hypochlorous acid
Woods, A. A. & Davies, Michael J., 15 Nov 2003, In: Biochemical Journal. 376, Pt 1, p. 219-27 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Photo-oxidation of cells generates long-lived intracellular protein peroxides
Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Mar 2003, In: Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The retina: oxidative stress and diabetes
van Reyk, D. M., Gillies, M. C. & Davies, Michael J., 2003, In: Redox Report (Online). 8, 4, p. 187-92 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2002
Published
Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides
Hampton, M. B., Morgan, P. E. & Davies, Michael J., 11 Sep 2002, In: FEBS Letters. 527, 1-3, p. 289-92 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals
Hawkins, Clare Louise & Davies, Michael J., Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation
Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael J., 1 Aug 2002, In: Biochemical Journal. 365, Pt 3, p. 605-15 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins
Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 2 Jan 2002, In: FEBS Letters. 510, 1-2, p. 41-4 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones
Headlam, H. A. & Davies, Michael J., 1 Jun 2002, In: Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein
Knott, H. M., Baoutina, A., Davies, Michael J. & Dean, R. T., 15 Apr 2002, In: Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Induction of DNA damage by oxidised amino acids and proteins
Luxford, C., Dean, R. T. & Davies, Michael J., 2002, In: Biogerontology. 3, 1-2, p. 95-102 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products
Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Jul 2002, In: Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack
Morgan, P. E., Dean, R. T. & Davies, Michael J., Apr 2002, In: European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Analysis of aliphatic amino acid alcohols in oxidized proteins
Morin, B., Fu, S., Wang, H., Davies, Michael J. & Dean, R. T., 2002, In: Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s
Pattison, D. I., Dean, R. T. & Davies, Michael J., 1 Aug 2002, In: Toxicology. 177, 1, p. 23-37 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues
Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael J., Jul 2002, In: Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Reaction between protein radicals and other biomolecules
Østdal, H., Davies, Michael J. & Andersen, H. J., 15 Jul 2002, In: Free Radical Biology & Medicine. 33, 2, p. 201-9 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2001
Published
Photo-oxidation of proteins and its role in cataractogenesis
Davies, Michael J. & Truscott, R. J., 2001, In: Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Generation and propagation of radical reactions on proteins
Hawkins, C. L. & Davies, Michael J., 2 Apr 2001, In: B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis
Hawkins, C. L., Brown, B. E. & Davies, Michael J., 15 Nov 2001, In: Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals
Hawkins, C. L. & Davies, Michael J., Aug 2001, In: Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Protein oxidation and ageing
Linton, S., Davies, Michael J. & Dean, R. T., Sep 2001, In: Experimental Gerontology. 36, 9, p. 1503-18 16 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds
Pattison, D. I. & Davies, Michael J., 2001, In: Chemical Research in Toxicology. 14, 10, p. 1453-64 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
An investigation of the chromium oxidation state of a monoanionic chromium tris(catecholate) complex by X-ray absorption and EPR spectroscopies
Pattison, D. I., Levina, A., Davies, Michael J. & Lay, P. A., 15 Jan 2001, In: Inorganic Chemistry. 40, 2, p. 214-7 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity
Pattison, D. I., Davies, Michael J., Levina, A., Dixon, N. E. & Lay, P. A., 2001, In: Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2000
Published
Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates
Davies, Michael J. & Hawkins, C. L., Dec 2000, In: Free Radical Research. 33, 6, p. 719-29 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract
Garner, B., Davies, Michael J. & Truscott, R. J., Jan 2000, In: Experimental Eye Research. 70, 1, p. 81-8 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals
Hawkins, C. L. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 1, p. 57-9 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains
Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael J., Nov 2000, In: Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA
Luxford, C., Dean, R. T. & Davies, Michael J., Jul 2000, In: Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
An investigation into the genotoxic species generated during reduction of chromium(VI) by catechol(amine)s
Pattison, D. I., Lay, P. A. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 2-3, p. 130-2 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers
Pattison, D. I., Lay, P. A. & Davies, Michael J., 26 Jun 2000, In: Inorganic Chemistry. 39, 13, p. 2729-39 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive peroxides
Wright, A., Hawkins, C. L. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 2-3, p. 159-61 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1999
Published
Stable markers of oxidant damage to proteins and their application in the study of human disease
Davies, Michael J., Fu, S., Wang, H. & Dean, R. T., Dec 1999, In: Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael J., 1 Jun 1999, In: Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
Hazell, L. J., Davies, Michael J. & Stocker, R., 1999, In: Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Myoglobin-induced oxidative damage: evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants
Irwin, J. A., Ostdal, H. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 94-104 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA
Luxford, C., Morin, B., Dean, R. T. & Davies, Michael J., 15 Nov 1999, In: Biochemical Journal. 344 Pt 1, p. 125-34 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?
Ostdal, H., Andersen, H. J. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Lipid oxidation in human low-density lipoprotein induced by metmyoglobin/H2O2: involvement of alpha-tocopheroxyl and phosphatidylcholine alkoxyl radicals
Witting, P. K., Willhite, C. A., Davies, Michael J. & Stocker, R., Dec 1999, In: Chemical Research in Toxicology. 12, 12, p. 1173-81 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1998
Published
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
Fu, S., Davies, Michael J., Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation
Hawkins, C. L. & Davies, Michael J., Jun 1998, In: Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael J., 15 Jun 1998, In: Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes
Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael J., 1998, In: Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation
Morin, B., Bubb, W. A., Davies, Michael J., Dean, R. T. & Fu, S., Nov 1998, In: Chemical Research in Toxicology. 11, 11, p. 1265-73 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage
Morin, B., Davies, Michael J. & Dean, R. T., 15 Mar 1998, In: Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing
Park, J. I., Grant, C. M., Davies, Michael J. & Dawes, I. W., 4 Sep 1998, In: The Journal of Biological Chemistry. 273, 36, p. 22921-8 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Photodynamically generated bovine serum albumin radicals: evidence for damage transfer and oxidation at cysteine and tryptophan residues
Silvester, J. A., Timmins, G. S. & Davies, Michael J., 15 Mar 1998, In: Free Radical Biology & Medicine. 24, 5, p. 754-66 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin
Silvester, J. A., Timmins, G. S. & Davies, Michael J., 15 Feb 1998, In: Archives of Biochemistry and Biophysics. 350, 2, p. 249-58 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite
Thomas, S. R., Davies, Michael J. & Stocker, R., 1998, In: Chemical Research in Toxicology. 11, 5, p. 484-94 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1997
Published
Biochemistry and pathology of radical-mediated protein oxidation
Dean, R. T., Fu, S., Stocker, R. & Davies, Michael J., 1997, In: Biochemical Journal. 324 ( Pt 1), p. 1-18 18 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?
Hawkins, C. L. & Davies, Michael J., 27 Feb 1997, In: B B A - Reviews on Cancer. 1360, 1, p. 84-96 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Absence of synproportionation between oxy and ferryl leghemoglobin. off
Mathieu, C., Swaraj, K., Davies, Michael J., Trinchant, J. C. & Puppo, A., Aug 1997, In: Free Radical Research. 27, 2, p. 165-71 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A kinetic and ESR investigation of iron(II) oxalate oxidation by hydrogen peroxide and dioxygen as a source of hydroxyl radicals
Park, J. S., Wood, P. M., Davies, Michael J., Gilbert, B. C. & Whitwood, A. C., Nov 1997, In: Free Radical Research. 27, 5, p. 447-58 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1996
Published
Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias
Collis, C. S., Rice-Evans, C. & Davies, Michael J., Apr 1996, In: International Journal of Biochemistry & Cell Biology. 28, 4, p. 405-13 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage
Davies, Michael J., 1 Dec 1996, In: Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Xanthine oxidase activity and free radical generation in patients with sepsis syndrome
Galley, H. F., Davies, Michael J. & Webster, N. R., 1996, In: Critical Care Medicine. 24, 10, p. 1649-53 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Benzoyl peroxide-induced damage to DNA and its components: direct evidence for the generation of base adducts, sugar radicals, and strand breaks
Hazlewood, C. & Davies, Michael J., 1 Aug 1996, In: Archives of Biochemistry and Biophysics. 332, 1, p. 79-91 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage
Moreau, S., Davies, Michael J., Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In: The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte
Murphy, P. G., Davies, Michael J., Columb, M. O. & Stratford, N., Apr 1996, In: British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1995
Published
Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species
Moreau, S., Davies, Michael J. & Puppo, A., 16 Aug 1995, In: Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1994
Published
A hydrogen-donating monohydroxamate scavenges ferryl myoglobin radicals
Cooper, C. E., Green, E. S., Rice-Evans, C. A., Davies, Michael J. & Wrigglesworth, J. M., Apr 1994, In: Free Radical Research. 20, 4, p. 219-27 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review

ID: 38036205

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