Clare Louise Hawkins
Professor MSO
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- 2010
Cellular effects of peptide and protein hydroperoxides
Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 15 Apr 2010, In: Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ability of hypochlorous acid and N-chloramines to chlorinate DNA and its constituents
Stanley, N. R., Pattison, D. I. & Hawkins, Clare Louise, 19 Jul 2010, In: Chemical Research in Toxicology. 23, 7, p. 1293-302 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages
Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael J., 15 Aug 2010, In: Biochemical Journal. 430, 1, p. 161-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation - an EPR study
Jansson, P. J., Hawkins, Clare Louise, Lovejoy, D. B. & Richardson, D. R., Nov 2010, In: Journal of Inorganic Biochemistry. 104, 11, p. 1224-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts
Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 30 Nov 2010, In: Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome
Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael J., 15 Jan 2011, In: Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone affect crucial thiol systems required for ribonucleotide reductase activity
Yu, Y., Suryo Rahmanto, Y., Hawkins, Clare Louise & Richardson, D. R., Jun 2011, In: Molecular Pharmacology. 79, 6, p. 921-31 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase
Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes
Lok, H. C., Suryo Rahmanto, Y., Hawkins, Clare Louise, Kalinowski, D. S., Morrow, C. S., Townsend, A. J., Ponka, P. & Richardson, D. R., 2 Jan 2012, In: The Journal of Biological Chemistry. 287, 1, p. 607-18 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid - benign or deadly?
Barrett, T. J. & Hawkins, Clare Louise, 20 Feb 2012, In: Chemical Research in Toxicology. 25, 2, p. 263-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates
Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, Michael J. & Hawkins, Clare Louise, 15 Mar 2012, In: Free Radical Biology & Medicine. 52, 6, p. 1075-85 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reduced circulating oxidized LDL is associated with hypocholesterolemia and enhanced thiol status in Gilbert syndrome
Boon, A., Hawkins, Clare Louise, Bisht, K., Coombes, J. S., Bakrania, B., Wagner, K. & Bulmer, A. C., 15 May 2012, In: Free Radical Biology & Medicine. 52, 10, p. 2120-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids
Pattison, D. I., Davies, Michael J. & Hawkins, Clare Louise, Aug 2012, In: Free Radical Research. 46, 8, p. 975-95 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of proteins susceptible to thiol oxidation in endothelial cells exposed to hypochlorous acid and N-chloramines
Summers, F. A., Forsman Quigley, A. & Hawkins, Clare Louise, 24 Aug 2012, In: Biochemical and Biophysical Research Communications. 425, 2, p. 157-61 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)
Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K., Davies, Michael J. & Hawkins, Clare Louise, 15 Jan 2013, In: Biochemical Journal. 449, 2, p. 531-42 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells
Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael J. & Hawkins, Clare Louise, Dec 2013, In: Free Radical Biology & Medicine. 65, p. 1352-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction
Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael J., Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MODULATION OF ENDOTHELIAL CELL FUNCTION BY THE MYELOPEROXIDASE-DERIVED OXIDANT HYPOCHLOROUS ACID (HOCl) AND ITS CONTRIBUTION TO ATHEROSCLEROSIS
Rayner, B. S., Lloyd, M. M., Summers, F. A., Davies, Michael J. & Hawkins, Clare Louise, 2014, In: Hypertension.Research output: Contribution to journal › Journal article › Research › peer-review
Detection and characterisation of radicals in biological materials using EPR methodology
Hawkins, Clare Louise & Davies, Michael J., Feb 2014, In: B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.Research output: Contribution to journal › Review › Research › peer-review
Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides
Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, Clare Louise & Davies, Michael J., May 2014, In: Free Radical Biology & Medicine. 70, p. 96-105 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparative reactivity of myeloperoxidase-derived oxidants with mammalian cells
Rayner, B. S., Love, D. T. & Hawkins, Clare Louise, Jun 2014, In: Free Radical Biology & Medicine. 71, p. 240-55 16 p.Research output: Contribution to journal › Journal article › Commissioned › peer-review
Role of cyanate in the induction of vascular dysfunction during uremia: more than protein carbamylation?
Hawkins, Clare Louise, Nov 2014, In: Kidney International. 86, 5, p. 875-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants
Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael J., Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In: Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael J. & Hawkins, Clare Louise, Jul 2015, In: Free Radical Biology & Medicine. 84, p. 279-288 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion
Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael J., Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In: Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 173742266
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
185
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Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
162
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Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space
Research output: Contribution to journal › Journal article › Research › peer-review
Published