Clare Louise Hawkins

Clare Louise Hawkins

Professor with special responsibilities


  1. 2002
  2. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides : formation of chloramines and nitrogen-centered radicals. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 15, No. 1, 01.2002, p. 83-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins. / Hawkins, Clare Louise; Rees, Martin D; Davies, Michael Jonathan.

    In: FEBS letters, Vol. 510, No. 1-2, 02.01.2002, p. 41-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Singlet oxygen-mediated protein oxidation : evidence for the formation of reactive side chain peroxides on tyrosine residues. / Wright, Adam; Bubb, William A; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Photochemistry and Photobiology, Vol. 76, No. 1, 07.2002, p. 35-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Reaction of protein chloramines with DNA and nucleosides : evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation. / Hawkins, Clare Louise; Pattison, David I; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 365, No. Pt 3, 01.08.2002, p. 605-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2003
  7. Published

    Photo-oxidation of cells generates long-lived intracellular protein peroxides. / Wright, Adam; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 34, No. 6, 15.03.2003, p. 637-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins : absolute rate constants, product analysis, and computational modeling. / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 16, No. 4, 04.2003, p. 439-49.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines : evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation. / Rees, Martin D; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Journal of the American Chemical Society, Vol. 125, No. 45, 12.11.2003, p. 13719-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2004
  11. Published

    EPR spin trapping of protein radicals. / Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Free Radical Biology & Medicine, Vol. 36, No. 9, 2004, p. 1072-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates. / Rees, Martin D; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 381, No. Pt 1, 01.07.2004, p. 175-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2005
  14. Inactivation of protease inhibitors and lysozyme by hypochlorous acid : role of side-chain oxidation and protein unfolding in loss of biological function. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 18, No. 10, 10.2005, p. 1600-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 39, No. 7, 01.10.2005, p. 900-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 18, No. 11, 11.2005, p. 1669-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2006
  18. Sensitizer-mediated photooxidation of histidine residues : evidence for the formation of reactive side-chain peroxides. / Agon, Vanessa V; Bubb, William A; Wright, Adam; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 40, No. 4, 15.02.2006, p. 698-710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2007
  20. Hypochlorous acid-mediated protein oxidation : how important are chloramine transfer reactions and protein tertiary structure? / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Biochemistry, Vol. 46, No. 34, 28.08.2007, p. 9853-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2008
  22. Mammalian heme peroxidases : from molecular mechanisms to health implications. / Davies, Michael Jonathan; Hawkins, Clare Louise; Pattison, David I; Rees, Martin D.

    In: Antioxidants & Redox Signaling, Vol. 10, No. 7, 07.2008, p. 1199-234.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines. / Summers, Fiona A; Morgan, Philip E; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Chemical Research in Toxicology, Vol. 21, No. 9, 09.2008, p. 1832-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid. / Lloyd, Mitchell M; van Reyk, David M; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Biochemical Journal, Vol. 414, No. 2, 01.09.2008, p. 271-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin. / Szuchman-Sapir, Andrea J; Pattison, David I; Ellis, Natasha A; Hawkins, Clare Louise; Davies, Michael Jonathan; Witting, Paul K.

    In: Free Radical Biology & Medicine, Vol. 45, No. 6, 15.09.2008, p. 789-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins. / Morgan, Philip E; Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 45, No. 9, 01.11.2008, p. 1279-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation. / Hawkins, Clare Louise; Pattison, David I; Stanley, Naomi R; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 416, No. 3, 15.12.2008, p. 441-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2009
  29. Quantification of protein modification by oxidants. / Hawkins, Clare Louise; Morgan, Philip E; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 46, No. 8, 15.04.2009, p. 965-88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach. / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 22, No. 5, 05.2009, p. 807-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Singlet-oxygen-mediated amino acid and protein oxidation : formation of tryptophan peroxides and decomposition products. / Gracanin, Michelle; Hawkins, Clare Louise; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 47, No. 1, 01.07.2009, p. 92-102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. The role of hypothiocyanous acid (HOSCN) in biological systems. / Hawkins, Clare L.

    In: Free Radical Research, Vol. 43, No. 12, 12.2009, p. 1147-58.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  33. 2010
  34. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations. / Koelsch, Maud; Mallak, Roger; Graham, Garry G; Kajer, Tracey; Milligan, Marian K; Nguyen, Ly Q; Newsham, Dawn W; Keh, Jeremy S; Kettle, Anthony J; Scott, Kieran F; Ziegler, John B; Pattison, David I; Fu, Shanlin; Hawkins, Clare Louise; Rees, Martin D; Davies, Michael Jonathan.

    In: Biochemical Pharmacology, Vol. 79, No. 8, 15.04.2010, p. 1156-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

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