Clare Louise Hawkins

Clare Louise Hawkins

Professor MSO

ORCID: 0000-0003-2738-5089

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  1. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., May 2009, In: Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Cellular effects of peptide and protein hydroperoxides

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 15 Apr 2010, In: Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 30 Nov 2010, In: Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Role of macrophage extracellular traps in innate immunity and inflammatory disease

    Rasmussen, K. H. & Hawkins, Clare Louise, 2022, In: Biochemical Society Transactions. 50, 1, p. 21-32 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    MODULATION OF ENDOTHELIAL CELL FUNCTION BY THE MYELOPEROXIDASE-DERIVED OXIDANT HYPOCHLOROUS ACID (HOCl) AND ITS CONTRIBUTION TO ATHEROSCLEROSIS

    Rayner, B. S., Lloyd, M. M., Summers, F. A., Davies, Michael J. & Hawkins, Clare Louise, 2014, In: Hypertension.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Comparative reactivity of myeloperoxidase-derived oxidants with mammalian cells

    Rayner, B. S., Love, D. T. & Hawkins, Clare Louise, Jun 2014, In: Free Radical Biology & Medicine. 71, p. 240-55 16 p.

    Research output: Contribution to journal › Journal article › Commissioned › peer-review

  8. Published

    Role of hypochlorous acid (HOCl) and other inflammatory mediators in the induction of macrophage extracellular trap formation

    Rayner, B. S., Zhang, Y., Brown, B. E., Reyes, L., Cogger, V. C. & Hawkins, Clare Louise, 2018, In: Free Radical Biology and Medicine. 129, p. 25-34

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Characterization of the cellular effects of myeloperoxidase-derived oxidants on H9c2 cardiac myoblasts

    Reyes, L., Hawkins, Clare Louise & Rayner, B. S., 2019, In: Archives of Biochemistry and Biophysics. 665, p. 132-142

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Assessing the Efficacy of Dietary Selenomethionine Supplementation in the Setting of Cardiac Ischemia/Reperfusion Injury

    Reyes, L., Bishop, D. P., Hawkins, Clare Louise & Rayner, B. S., 2019, In: Antioxidants. 8, 546 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. CC-chemokine class inhibition attenuates pathological angiogenesis while preserving physiological angiogenesis

    Ridiandries, A., Tan, J. T. M., Ravindran, D., Williams, H., Medbury, H. J., Lindsay, L., Hawkins, Clare Louise, Prosser, H. C. G. & Bursill, C. A., Mar 2017, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31, 3, p. 1179-1192 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway

    Shu, N., Hägglund, Per Mårten, Cai, H., Hawkins, Clare Louise & Davies, Michael J., Jan 2020, In: Redox Biology. 29, UNSP 101400.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The role of RNA oxidation in islet dysfunction in Type 2 diabetes

    Sileikaite, I., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1 , p. S37-S38

    Research output: Contribution to journal › Conference abstract in journal › Research

  16. Published

    Detrimental Actions of Chlorinated Nucleosides on the Function and Viability of Insulin-Producing Cells

    Sileikaite-Morvaközi, I., Hansen, W. H., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2023, In: International Journal of Molecular Sciences. 24, 19, 13 p., 14585.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Ability of hypochlorous acid and N-chloramines to chlorinate DNA and its constituents

    Stanley, N. R., Pattison, D. I. & Hawkins, Clare Louise, 19 Jul 2010, In: Chemical Research in Toxicology. 23, 7, p. 1293-302 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Cellular responses to radical propagation from ion-implanted plasma polymer surfaces

    Stewart, C. A. C., Akhavan, B., Santos, M., Hung, J., Hawkins, Clare Louise, Bao, S., Wise, S. G. & Bilek, M. M. M., 2018, In: Applied Surface Science. 456, p. 701-710

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Identification of proteins susceptible to thiol oxidation in endothelial cells exposed to hypochlorous acid and N-chloramines

    Summers, F. A., Forsman Quigley, A. & Hawkins, Clare Louise, 24 Aug 2012, In: Biochemical and Biophysical Research Communications. 425, 2, p. 157-61 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines

    Summers, F. A., Morgan, P. E., Davies, Michael J. & Hawkins, Clare Louise, Sep 2008, In: Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin

    Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael J. & Witting, P. K., 15 Sep 2008, In: Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    8-Chloroadenosine induces apoptosis in human coronary artery endothelial cells through the activation of the unfolded protein response

    Tang, V., Fu, S., Rayner, B. S. & Hawkins, Clare Louise, 2019, In: Redox Biology. 26, 11 p., UNSP 101274.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development

    Tweeddale, H. J., Hawkins, Clare Louise, Janmie, J. F., Truscott, R. J. W. & Davies, Michael J., Oct 2016, In: Free Radical Research. 50, 10, p. 1116-1130 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 136, p. 118-134

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN−)

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Redox Biology. 36, 13 p., 101641.

    Research output: Contribution to journal › Journal article › Research › peer-review

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