Christina Christoffersen

Christina Christoffersen

Associate Professor


  1. 2018
  2. Published

    Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

    Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T. & 1 others, Clausen, Henrik, 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

    Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]

    Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael J., 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  5. 2019
  6. Published

    Apolipoprotein M/sphingosine-1-phosphate: novel effects on lipids, inflammation and kidney biology

    Bisgaard, L. S. & Christoffersen, Christina, 2019, In: Current Opinion in Lipidology. 30, 3, p. 212-217

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Diurnal regulation of sphingolipids in blood

    Brunkhorst, R., Pfeilschifter, W., Rajkovic, N., Pfeffer, M., Fischer, C., Korf, H. W., Christoffersen, Christina, Trautmann, S., Thomas, D., Pfeilschifter, J. & Koch, A., 2019, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 3, p. 304-311

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of menopause and exercise training on plasma apolipoprotein M and sphingosine-1-phosphate

    Yafasova, A., djc739, djc739, Egelund, J., Nyberg, M. P., Stallknecht, Bente Merete, Hellsten, Ylva, Nielsen, L. B. & Christoffersen, Christina, 2019, In: Journal of Applied Physiology. 126, 1, p. 214-220 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway

    Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Molecular Characterization of Microvesicular and Macrovesicular Steatosis Shows Widespread Differences in Metabolic Pathways

    Kristiansen, M., Veidal, S. S., Christoffersen, Christina, Jelsing, J. & Rigbolt, K. T. G., 2019, In: Lipids. 54, 1, p. 109-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Subclinical atherosclerosis in patients with cyanotic congenital heart disease

    Tarp, J. B., Sorgaard, M. H., Christoffersen, Christina, Jensen, A. S., Sillesen, Henrik, Celermajer, D., Eriksson, P., Estensen, M., Nagy, E., von Holstein-Rathlou, Niels-Henrik, Engstrøm, Thomas & Søndergaard, Lars, 2019, In: International Journal of Cardiology. 277, p. 97-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH

    Kristiansen, M. N. B., Veidal, S. S., Christoffersen, Christina, Feigh, M., Vrang, N., Roth, J. D., Erickson, M., Adorini, L. & Jelsing, J., 2019, In: B M C Gastroenterology. 19, 1, 11 p., 228 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis

    Mathiesen Janiurek, M., Soylu-Kucharz, R., Christoffersen, Christina, Kucharz, Krzysztof & Lauritzen, Martin, 25 Nov 2019, In: eLife. 8, 22 p., e49405.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding

    Tian, E., Wang, S., Zhang, L., Zhang, Y., Malicdan, M. C., Mao, Y., Christoffersen, Christina, Tabak, L. A., Schjoldager, Katrine Ter-Borch Gram & Ten Hagen, K. G., 10 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25196-25202

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2020
  16. Published

    Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair

    Ding, B. S., Yang, D., Swendeman, S. L., Christoffersen, Christina, Nielsen, L. B., Friedman, S. L., Powell, C. A., Hla, T. & Cao, Z., 2020, In: Developmental Cell. 53, 6, p. 677-690

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Apolipoprotein M and Risk of Type 2 Diabetes

    Hajny, Stefan, Christoffersen, M., Dalila, N., Nielsen, L. B., Tybjærg-Hansen, Anne & Christoffersen, Christina, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 9, p. 3046-3057

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Cardiovascular prognostic value of echocardiography and N terminal pro B-type natriuretic peptide in type 1 diabetes: The Thousand and 1 Study

    Rørth, R., Jørgensen, P. G., Andersen, H. U., Christoffersen, Christina, Goetze, Jens P. , Køber, Lars Valeur, Rossing, Peter & bqn654, bqn654, 2020, In: European Journal of Endocrinology. 182, 5, p. 481-488

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature

    Del Gaudio, I., Sreckovic, I., Zardoya-Laguardia, P., Bernhart, E., Christoffersen, Christina, Frank, S., Marsche, G., Illanes, S. E. & Wadsack, C., 2020, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1865, 4, 11 p., 158632.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effect of insulin on natriuretic peptide gene expression in porcine heart

    Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure

    Chirinos, J. A., Zhao, L., Jia, Y., Frej, C., Adamo, L., Mann, D., Shewale, S. V., Millar, J. S., Rader, D. J., French, B., Brandimarto, J., Margulies, K. B., Parks, J. S., Wang, Z., Sieffert, D. A., Fang, J., Sweitzer, N., Christoffersen, C., Dahlbäck, B., Car, B. D. & 3 others, Gordon, D. A., Cappola, T. P. & Javaheri, A., 2020, In: Circulation. 141, 18, p. 1463–1476

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Regional distribution and severity of arterial calcification in patients with chronic kidney disease stages 1-5: a cross-sectional study of the Copenhagen chronic kidney disease cohort

    Sorensen, I. M. H., Saurbrey, S. A. K., Hjortkjaer, H. O., Brainin, P., Carlson, N., Ballegaard, E. L. F., Kamper, A., Christoffersen, Christina, Feldt-Rasmussen, Bo, Kofoed, Klaus Fuglsang & Bro, S., 2020, In: BMC Nephrology. 21, 1, 11 p., 534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Vascular function in adults with cyanotic congenital heart disease

    Tarp, J. B., Clausen, P., Celermajer, D., Christoffersen, Christina, Jensen, A. S., Sorensen, K., Sillesen, Henrik, Estensen, M., Nagy, E., von Holstein-Rathlou, Niels-Henrik, Engstrøm, Thomas, Feldt-Rasmussen, Bo & Søndergaard, Lars, 2020, In: IJC Heart and Vasculature. 30, 7 p., 100632.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Neonatal HDL Counteracts Placental Vascular Inflammation via S1P-S1PR1 Axis

    Gaudio, I. D., Hendrix, S., Christoffersen, Christina & Wadsack, C., 25 Jan 2020, In: International Journal of Molecular Sciences. 21, 3, 789.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2021
  26. Published

    Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein

    Velagapudi, S., Rohrer, L., Poti, F., Feuerborn, R., Perisa, D., Wang, D., Panteloglou, G., Potapenko, A., Yalcinkaya, M., Hulsmeier, A. J., Hesse, B., Lukasz, A., Liu, M., Parks, J. S., Christoffersen, Christina, Stoffel, M., Simoni, M., Nofer, J. & von Eckardstein, A., 2021, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 41, 10, p. E468-E479 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Apolipoprotein M and its impact on endothelial dysfunction and inflammation in the cardiovascular system

    Yao Mattisson, I. & Christoffersen, Christina, 2021, In: Atherosclerosis. 334, p. 76-84

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Apolipoprotein M-A Marker or an Active Player in Type II Diabetes?

    Christoffersen, Christina, 2021, In: Frontiers in Endocrinology. 12, 10 p., 665393.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Carotid plaque thickness is increased in chronic kidney disease and associated with carotid and coronary calcification

    Bjergfelt, S. S., Sørensen, I. M. H., Hjortkjær, H., Landler, N., Ballegaard, E. L. F., Biering-Sørensen, Tor, Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Sillesen, Henrik, Christoffersen, Christina & Bro, S., 2021, In: PLoS ONE. 16, 16 p., e0260417.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 18392597