Carolyn F. Deacon

Carolyn F. Deacon

Associate Professor


  1. Published

    A Protein Preload Enhances the Glucose-Lowering Efficacy of Vildagliptin in Type 2 Diabetes. / Wu, T; Little, TL; Bound, MJ; Borg, M; Zhang, X; Deacon, Carolyn F.; Horowitz, Michael; Jones, KL; Rayner, CK.

    In: Diabetes Care, Vol. 39, No. 4, 2016, p. 511-517.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients. / Samkani, Amirsalar; Skytte, Mads Gustav Juul; Kandel, Daniel; Kjaer, Stine; Astrup, Arne; Deacon, Carolyn F.; Holst, Jens J; Madsbad, Sten; Rehfeld, Jens Frederik; Haugaard, Steen Bendix; Krarup, Thure.

    In: British Journal of Nutrition, Vol. 119, No. 8, 2018, p. 910-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A comparative review of DPP-4 inhibitors and sulphonylureas. / Deacon, Carolyn F.; Lebovitz, HE.

    In: Diabetes, Obesity and Metabolism, Vol. 18, 2016, p. 333-347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A review of dipeptidyl peptidase-4 inhibitors : Hot topics from randomized controlled trials. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 20, 02.2018, p. 34-46.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    A review of dipeptidyl peptidase-4 inhibitors. Hot topics from randomised controlled trials. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. Suppl. 1, 2018, p. 34-46.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite. / Wewer Albrechtsen, Nicolai J; Asmar, Ali; Jensen, Frederik; Törang, Signe; Simonsen, Lene; Kuhre, Rune E; Asmar, Meena; Veedfald, Simon; Plamboeck, Astrid; Knop, Filip K; Vilsbøll, Tina; Madsbad, Sten; Nauck, Michael A; Deacon, Carolyn F; Bülow, Jens; Holst, Jens J; Hartmann, Bolette.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 313, No. 3, 01.09.2017, p. E284-E291.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow. / Jensen, Elisa Pouline; Poulsen, Steen Seier; Kissow, Hannelouise; Holstein-Rathlou, Niels-Henrik; Deacon, Carolyn F.; Jensen, Boye L.; Holst, Jens J.; Sorensen, Charlotte M.

    In: A J P: Renal Physiology (Online), Vol. 308, No. 8, 15.04.2015, p. F867-F877.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Acute Effects of Dietary Carbohydrate Restriction on Glycemia, Lipemia and Appetite Regulating Hormones in Normal-Weight to Obese Subjects. / Samkani, Amirsalar Agertoft; Skytte, Mads J; Thomsen, Mads N; Astrup, Arne; Deacon, Carolyn F; Holst, Jens Juul; Madsbad, Sten; Rehfeld, Jens Frederik; Krarup, Thure; Haugaard, Steen B.

    In: Nutrients, Vol. 10, No. 9, 1285, 09.2018, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice. / Christiansen, Charlotte B.; Lind, Sara J.; Svendsen, Berit; Balk-Møller, Emilie; Dahlby, Tina; Kuhre, Rune E; Hartmann, Bolette; Mandrup-Poulsen, Thomas; Deacon, Carolyn F; Albrechtsen, Nicolai J. Wewer; Holst, Jens J.

    In: Physiological Reports, Vol. 6, No. 13, e13788, 2018, p. 1-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones. / Olthof, MR; van Dijk, AE; Deacon, Carolyn F.; Heine, RJ; van Dam, RM .

    In: Nutrition & Metabolism, Vol. 8, 2011, p. Artikel 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide : A randomized controlled trial in patients with type 2 diabetes. / Nauck, Michael A; Kahle, Melanie; Baranov, Oleg; Deacon, Carolyn F; Holst, Jens J.

    In: Diabetes, Obesity and Metabolism, Vol. 19, No. 2, 06.02.2017, p. 200-207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes. / Deacon, Carolyn F.

    In: Current Opinion in Investigational Drugs, Vol. 9, No. 4, 2008, p. 402-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future. / Madsbad, S; Kielgast, U; Asmar, M; Deacon, C F; Torekov, Signe Sørensen; Holst, J J.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 5, 05.2011, p. 394-407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects. / Deacon, C.F.; Nauck, M.A.; Nielsen, M.T.; Pridal, L.; Holst, Jens Juul.

    In: Diabetes, No. 44, 1995, p. 1126-1131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published
  17. Published

    Cephalic phase secretion of insulin and other enteropancreatic hormones in humans. / Veedfald, Simon; Plamboeck, Astrid; Deacon, Carolyn F; Hartmann, Bolette; Knop, Filip K; Lauritsen, Tina Vilsbøll; Holst, Jens J.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 310, No. 1, 01.01.2016, p. G43-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty. / Plamboeck, Astrid; Veedfald, Simon; Deacon, Carolyn; Hartmann, Bolette; Wettergren, Andre; Svendsen, Lars Bo; Meisner, Søren; Hovendal, Claus; Knop, Filip Krag; Vilsbøll, Tina; Holst, Jens Juul.

    In: European Journal of Endocrinology, Vol. 169, 23.05.2013, p. 187-201.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production. / Albrechtsen, Nicolai J. Wewer; Kuhre, Rune E.; Hornburg, Daniel; Jensen, Christian Z.; Hornum, Mads; Dirksen, Carsten; Svane, Maria; Gasbjerg, Laerke S.; Jorgensen, Nils B.; Gabe, Maria N.; Balk-Moller, Emilie; Albrechtsen, Reidar; Winther-Sorensen, Marie; Galsgaard, Katrine D.; Meissner, Felix; Jorsal, Tina; Lund, Asger; Vilsboll, Tina; Eliasen, Rasmus; Bojsen-Moller, Kirstine N.; Idorn, Thomas; Deacon, Carolyn F.; Knop, Filip K.; Rosenkilde, Mette M.; Hartmann, Bolette; Feldt-Rasmussen, Bo; Mann, Matthias; Madsbad, Sten; Holst, Jens J.

    In: Cell Reports, Vol. 21, No. 6, 11.2017, p. 1452-1460.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Circulation and degradation of GIP and GLP-1. / Deacon, Carolyn F.

    In: Hormone and Metabolic Research, No. 36, 2004, p. 761-765.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Commentary: Is endogenous GLP-1 the only important enhancer of glucose-induced insulin secretion in type 2 diabetes? / Deacon, Carolyn F.

    In: Diabetes, Vol. 61, No. 9, 2012, p. 2219-2220.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas. / Deacon, Carolyn F.; Lebovitz, HE.

    In: Diabetes, Obesity and Metabolism, Vol. 18, No. 4, 2016, p. 333-347.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia. / Craig, Colleen M; Liu, Li-Fen; Deacon, Carolyn F; Holst, Jens J; McLaughlin, Tracey L.

    In: Diabetologia, Vol. 60, No. 3, 03.2017, p. 531-540.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    DPP-4 inhibition – advances in our understanding of diabetes management. / Deacon, Carolyn F.; Holst, Jens Juul.

    In: European Endocrinology, Vol. 4, 2009, p. 47-49.

    Research output: Contribution to journalReviewResearch

  25. Published

    DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes. / Deacon, Carolyn F; Carr, Richard D; Holst, Jens Juul.

    In: Frontiers in Bioscience, Vol. 13, 2008, p. 1780-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    DPP-4 inhibitors. / Deacon, Carolyn F.

    Handbook of incretin therapies in type 2 diabetes. ed. / S Gough. Switzerland : Springer, 2016. p. 45-60.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  27. Published

    Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide. / Deacon, C.F.; Nauck, M.A.; Meier, J.; Hücking, K.; Holst, J.J.

    In: Journal of Clinical Endocrinology and Metabolism, No. 85, 2000, p. 3575-3581.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo. / Deacon, C.F.; Johnsen, A.H.; Holst, Jens Juul.

    In: Journal of Clinical Endocrinology and Metabolism, No. 80, 1995, p. 952-957.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men. / Eelderink, Coby; Noort, Martijn W J; Sozer, Nesli; Koehorst, Martijn; Holst, Jens J; Deacon, Carolyn F; Rehfeld, Jens F; Poutanen, Kaisa; Vonk, Roel J; Oudhuis, Lizette; Priebe, Marion G.

    In: European Journal of Nutrition, Vol. 56, No. 3, 2017, p. 1063-1076.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men. / Lindgren, Ola; Mari, Andrea; Deacon, Carolyn F; Carr, Richard D; Winzell, Maria Sörhede; Vikman, Jenny; Ahrén, Bo.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 8, 2009, p. 2887-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Differential regional metabolism of glucagon in anesthetized pigs. / Deacon, Carolyn F; Kelstrup, Mette; Trebbien, Ramona; Klarskov, Letty; Olesen, Mette; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 285, No. 3, 2003, p. E552-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Dipeptidyl peptidase 4 inhibition with sitagliptin: a new therapy for type 2 diabetes. / Deacon, Carolyn F.

    In: Expert Opinion on Investigational Drugs, Vol. 16, No. 4, 2007, p. 533-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective. / Deacon, Carolyn F; Holst, Jens J.

    In: Biochemical and Biophysical Research Communications, Vol. 294, No. 1, 2002, p. 1-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig. / Deacon, C.F.; Hughes, T.E.; Holst, J.J.

    In: Diabetes, No. 47, 1998, p. 764-769.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs. / Deacon, C.F.; Danielsen, P.; Klarskov, L.; Holst, J.J.; Olesen, M.

    In: Diabetes, No. 50, 2001, p. 1588-1597.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes. / Deacon, Carolyn F; Holst, Jens J.

    In: International Journal of Biochemistry & Cell Biology, Vol. 38, No. 5-6, 2005, p. 831-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity. / Deacon, C.F.; Knudsen, L.B.; Madsen, K.; Wiberg, F.C.; Jacobsen, O.; Holst, J.J.

    In: Diabetologia, No. 41, 1998, p. 271-278.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs. / Hjøllund, K R; Deacon, C F; Holst, Jens Juul.

    In: Diabetologia, Vol. 54, No. 8, 2011, p. 2206-8.

    Research output: Contribution to journalLetterResearchpeer-review

  39. Published

    Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1. / Migoya, E M; Bergeron, R; Miller, J L; Snyder, R N K; Tanen, M; Hilliard, D; Weiss, B; Larson, P; Gutierrez, M; Jiang, G; Liu, F.; Pryor, K A; Yao, J; Zhu, L; Holst, Jens Juul; Deacon, C; Herman, G; Thornberry, N; Amatruda, J; Williams-Herman, D; Wagner, J A; SinhaRoy, R.

    In: Clinical Pharmacology and Therapeutics, Vol. 88, No. 6, 01.12.2010, p. 801-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes : comparison, efficacy and safety. / Deacon, Carolyn F; Holst, Jens Juul.

    In: Expert Opinion on Pharmacotherapy, Vol. 14, No. 15, 10.2013, p. 2047-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 1, 01.2011, p. 7-18.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Dissociated incretin hormone response to protein versus fat ingestion in obese subjects. / Lindgren, O; Carr, RD; Holst, Jens Juul; Deacon, Carolyn F.; Ahren, B.

    In: Diabetes, Obesity and Metabolism Online, Vol. 13, No. 9, 07.2011, p. 863-865.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Do we know the true mechanism of action of the DPP-4 inhibitors? / Andersen, Emilie S.; Deacon, Carolyn F.; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 1, 2018, p. 34-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes. / Albrechtsen, Nicolai Jacob Wewer; Kuhre, Rune Ehrenreich; Windeløv, Johanne Agerlin; Ørgaard, Anne; Deacon, Carolyn F.; Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 311, No. 2, 2016, p. E302-E309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients. / Yabe, Daisuke; Kuroe, Akira; Watanabe, Koin; Iwasaki, Masahiro; Hamasaki, Akihiro; Hamamoto, Yoshiyuki; Harada, Norio; Yamane, Shunsuke; Lee, Soushou; Murotani, Kenta; Deacon, Carolyn F; Holst, Jens Juul; Hirano, Tsutomu; Inagaki, Nobuya; Kurose, Takeshi; Seino, Yutaka.

    In: Journal of Diabetes and its Complications, Vol. 29, 2015, p. 413-421.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Effect of Sitagliptin therapy on postprandial lipoprotein levels in patients with type 2 diabetes. / Tremblay, AJ; Lamarche, B; Deacon, Carolyn F.; Weisnagel, SJ; Couture, P.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 4, 04.2011, p. 366-373.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes. / Foley, J.E.; Ligueros-Saylan, M.; He, Y.L.; Holst, Jens Juul; Deacon, Carolyn F.; Dunning, B.E.; Leone-Jones, A.; Yu, T.; Kelley, D.E.

    In: Hormone and Metabolic Research, Vol. 40, No. 10, 2008, p. 727-730.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes. / Herman, Gary A; Bergman, Arthur; Stevens, Catherine; Kotey, Paul; Yi, Bingming; Zhao, Peng; Dietrich, Bruno; Golor, George; Schrodter, Andreas; Keymeulen, Bart; Lasseter, Kenneth C; Kipnes, Mark S; Snyder, Karen; Hilliard, Deborah; Tanen, Michael; Cilissen, Caroline; De Smet, Marina; de Lepeleire, Inge; Van Dyck, Kristien; Wang, Amy Q; Zeng, Wei; Davies, Michael J; Tanaka, Wesley; Holst, Jens J; Deacon, Carolyn F; Gottesdiener, Keith M; Wagner, John A.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 91, No. 11, 2006, p. 4612-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes. / Foley, J E; Ligueros-Saylan, M; He, Y-L; Holst, Jens Juul; Deacon, C F; Dunning, B E; Leone-Jones, A; Yu, T; Kelley, D E.

    In: Hormone and Metabolic Research. Supplement, Vol. 40, No. 10, 10.2008, p. 727-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure : A Pilot Study. / Clarke, Sophie J.; Pettit, Stephen; Giblett, Joel P.; Zhao, Tian; Kydd, Anna C.; Albrechtsen, Nicolai J. W.; Deacon, Carolyn F.; Parameshwar, Jayan; Hoole, Stephen P.

    In: Clinical Therapeutics, Vol. 41, No. 1, 2019, p. 118-127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes. / Henry, R R; Smith, Susanne; Schwartz, Saul; Mudaliar, S R; Deacon, C F; Holst, Jens Juul; Duan, R Y; Chen, R S; List, J F.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 9, 2011, p. 850-858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus. / Stephens, J W; Bodvarsdottir, T B; Wareham, K; Prior, S L; Bracken, R M; Lowe, G D; Rumley, A; Dunseath, G; Luzio, S; Deacon, C F; Holst, Jens Juul; Bain, S C.

    In: Diabetes Research and Clinical Practice, Vol. 94, No. 2, 11.2011, p. 199-206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose. / Vardarli, Irfan; Arndt, Elisabeth; Deacon, Carolyn F; Holst, Jens Juul; Nauck, Michael A.

    In: Diabetes, Vol. 63, No. 2, 02.2014, p. 663-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Effects of sitagliptin on blood pressure and heart rate in response to intraduodenal glucose infusion in type 2 diabetes. / Wu, T; Trahair, LG; Bound, MJ; Deacon, Carolyn F.; Horowitz, M; Rayner, CK; Jones, KL.

    In: Diabetic Medicine, Vol. 32, No. 5, 2015, p. 595-600.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Effects of sitagliptin on glycemia, incretin hormones, and antropyloroduodenal motility in response to intraduodenal glucose infusion in healthy lean and obese humans, and patients with type 2 diabetes treated with or without metformin. / Wu, T; Ma, J; Bound, MJ; Checklin, H; Deacon, Carolyn F.; Jones, KI; Horowitz, M; Raynor, CK.

    In: Diabetes, Vol. 63, No. 8, 2014, p. 2776-2787.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Effects of sitagliptin therapy on markers of low-grade inflammation and cell adhesion molecules in patients with type 2 diabetes. / Tremblay, AJ ; Lamarche, B; Deacon, Carolyn F.; Weisnagel, SJ; Couture, P.

    In: Metabolism, Vol. 63, No. 9, 2014, p. 1141-1148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Effects of the dipeptidyl peptidase IV inhibitor, vildagliptin, on glycemic, gut hormone, triglyceride, energy expenditure and energy intake responses to intraduodenal fat infusion in healthy males. / Heruc, GA; Horowitz, Michael; Deacon, Carolyn F.; Feinle-Bisset, C; Rayner, CK; Luscombe-Marsh, N; Little, Tanya J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 307, No. 9, 2014, p. E830-E837.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance. / Rosenstock, Julio; Foley, James E; Rendell, Marc; Landin-Olsson, Mona; Holst, Jens J; Deacon, Carolyn F; Rochotte, Erika; Baron, Michelle A.

    In: Diabetes Care, Vol. 31, No. 1, 2008, p. 30-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Elevated Postoperative Endogenous GLP-1 Levels Mediate Effects of Roux-en-Y Gastric Bypass on Neural Responsivity to Food Cues. / Ten Kulve, Jennifer S; Veltman, Dick J; Gerdes, Victor E A; van Bloemendaal, Liselotte; Barkhof, Frederik; Deacon, Carolyn F; Holst, Jens J; Drent, Madeleine L; Diamant, Michaela; IJzerman, Richard G.

    In: Diabetes Care, Vol. 40, No. 11, 11.2017, p. 1522-1529.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes. / Ten Kulve, Jennifer S; Veltman, Dick J; van Bloemendaal, Liselotte; Barkhof, Frederik; Deacon, Carolyn F; Holst, Jens J; Konrad, Robert J; Sloan, John H; Drent, Madeleine L; Diamant, Michaela; IJzerman, Richard G.

    In: Diabetologia, Vol. 58, No. 12, 12.2015, p. 2688-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Enhanced glucagon-like peptide- 1 (GLP-1) response to oral glucose in glucose intolerant HIV-infected patients on antiretroviral therapy. / Andersen, O.; Haugaard, S.B.; Holst, Jens Juul; Deacon, Carolyn F.; Iversen, J.; Andersen, U.B.; Nielsen, J.O.; Madsbad, S.

    In: HIV Medicine, Vol. 6, 2005, p. 91-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy. / Andersen, O; Haugaard, S B; Holst, Jens Juul; Deacon, C F; Iversen, J; Andersen, U B; Nielsen, J O; Madsbad, S.

    In: HIV Medicine, Vol. 6, No. 2, 03.2005, p. 91-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats. / Simonsen, Lotte; Pilgaard, Sofie; Orskov, Cathrine; Rosenkilde, Mette M; Hartmann, Bolette; Holst, Jens J; Deacon, Carolyn F.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 293, No. 1, 2007, p. G288-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs. / Simonsen, L; Holst, Jens Juul; Deacon, C F.

    In: Diabetologia, Vol. 49, No. 4, 04.2006, p. 706-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs. / Simonsen, L.; Holst, J.J.; Deacon, C.F.

    In: Diabetologia, Vol. 49, No. 4, 2006, p. 706-712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition : a randomized, prospective comparison of sitagliptin and vildagliptin treatment. / Baranov, Oleg; Kahle, Melanie; Deacon, Carolyn F; Holst, Jens J; Nauck, Michael A.

    In: Diabetes, Obesity and Metabolism, Vol. 18, No. 11, 11.2016, p. 1100-1109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    For debate: Are antidiabetic actions of DPP-IV inhibitors mediated by glucagon-like peptide- 1? / Holst, Jens Juul; Deacon, Carolyn F.

    In: Diabetologia, No. 48, 2005, p. 612-615.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men. / Matikainen, N; Söderlund, S; Björnson, E; Bogl, L H; Pietiläinen, K H; Hakkarainen, A; Lundbom, N; Eliasson, B; Räsänen, S M; Rivellese, A; Patti, L; Prinster, A; Riccardi, G; Després, J-P; Alméras, N; Holst, J J; Deacon, C F; Borén, J; Taskinen, M-R.

    In: Nutrition, Metabolism & Cardiovascular Diseases, Vol. 27, No. 6, 06.2017, p. 534-542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes. / Mentis, Nikolaos; Vardarli, Irfan; Köthe, Lars D; Holst, Jens Juul; Deacon, Carolyn F; Theodorakis, Michael; Meier, Juris J; Nauck, Michael A.

    In: Diabetes, Vol. 60, No. 4, 2011, p. 1270-1276.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations. / Deacon, Carolyn F; Plamboeck, Astrid; Rosenkilde, Mette M; de Heer, Jocelyn; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 291, No. 3, 2006, p. E468-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    GLP-1 Is a Coronary Artery Vasodilator in Humans. / Clarke, Sophie J.; Giblett, Joel P.; Yang, Lucy L.; Hubsch, Annette; Zhao, Tian; Aetesam-ur-Rahman, Muhammad; West, Nick E. J.; O'Sullivan, Michael; Figg, Nichola; Bennett, Martin; Albrechtsen, Nicolai J. Wewer; Deacon, Carolyn F.; Cheriyan, Joseph; Hoole, Stephen P.

    In: Journal of the American Heart Association, Vol. 7, No. 22, e010321, 20.11.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics. / Sturis, Jeppe; Gotfredsen, Carsten F; Rømer, John; Rolin, Bidda; Ribel, Ulla; Brand, Christian L; Wilken, Michael; Wassermann, Karsten; Deacon, Carolyn F; Carr, Richard D; Knudsen, Lotte Bjerre.

    In: British Journal of Pharmacology, Vol. 140, No. 1, 2003, p. 123-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    GLP-1 signals via ERK in peripheral nerve and prevents nerve dysfunction in diabetic mice. / Jolivalt, CG; Fineman, M; Deacon, Carolyn F.; Carr, RD; Calcutt, NA.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 11, 11.2011, p. 990-1000.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion. / Deacon, Carolyn F; Plamboeck, Astrid; Møller, Søren; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 282, No. 4, 2002, p. E873-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia. / Meier, J J; Gallwitz, B; Siepmann, N; Holst, Jens Juul; Deacon, C F; Schmidt, W E; Nauck, M A.

    In: Diabetologia, Vol. 46, No. 6, 06.2003, p. 798-801.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia. / Meier, J.J.; Gallwitz, N.; Siepmann, N.; Holst, Jens Juul; Deacon, C.F.; Schmidt, W.E.; Nauck, M.A.

    In: Diabetologia, No. 46, 2003, p. 798-801.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Ghrelin secretion in humans - a role for the vagus nerve? / Veedfald, S; Plamboeck, A; Hartmann, B; Vilsbøll, T; Knop, F K; Deacon, C F; Svendsen, L B; Holst, J J.

    In: Neurogastroenterology and Motility, Vol. 30, No. 6, e13295, 06.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Glucagon-like peptide 1 and inhibitors of dipeptidyl peptidase IV in the treatment of type 2 diabetes mellitus. / Holst, Jens Juul; Deacon, Carolyn F.

    In: Current Opinion in Pharmacology, Vol. 4, No. 6, 2004, p. 589-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes : a review of clinical trials. / Madsbad, Sten; Krarup, Thure; Deacon, Carolyn F; Holst, Jens Juul.

    In: Current Opinion in Clinical Nutrition and Metabolic Care, Vol. 11, No. 4, 07.2008, p. 491-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials. / Madsbad, Sten; Krarup, Thure; Deacon, Carolyn F; Holst, Jens Juul; Madsbad, Sten; Krarup, Thure; Deacon, Carolyn F; Holst, Jens J.

    In: Current Opinion in Clinical Nutrition and Metabolic Care, Vol. 11, No. 4, 2008, p. 491-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Glucagon-like peptide-1 : a basis for new approaches to the management of diabetes. / Deacon, C F; Holst, Jens Juul; Carr, R D.

    In: Drugs of Today, Vol. 35, No. 3, 03.1999, p. 159-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors. / Holst, Jens Juul; Deacon, C F.

    In: Diabetologia, Vol. 48, No. 4, 04.2005, p. 612-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Glucagon-like peptide-1 mediates the therapeutic actions of Dpp-IV inhibitors. / Holst, Jens Juul; Deacon, Carolyn F.

    In: Diabetologia, No. 48, 2005, p. 612-615.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published
  85. Published

    Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells. / Hansen, L.; Deacon, C.F.; Ørskov, C.; Holst, J.J.

    In: Endokrinologiya, No. 140, 1999, p. 5356-5363.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Glucagon-like peptide-1, glucose homeostasis and diabetes. / Holst, Jens Juul; Deacon, Carolyn F; Vilsbøll, Tina; Krarup, Thure; Madsbad, Sten.

    In: Trends in Molecular Medicine, Vol. 14, No. 4, 2008, p. 161-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. / Hansen, L; Deacon, C F; Orskov, C; Holst, J J.

    In: Molecular Endocrinology, Vol. 140, No. 11, 11.1999, p. 5356-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Glucagon-like peptide-1: A basis for new approaches to the management of Diabetes. / Deacon, C.F.; Holst, J.J.; Carr, R.D.

    In: Drugs of Today, No. 35, 1999, p. 159-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin. / Holst, Jens Juul; Deacon, Carolyn F.; Hartmann, Bolette; Pedersen, Jens.

    Handbook of Biologically Active Peptides . ed. / AJ Kastin. 2. ed. Elsevier, 2013. p. 1241-1250.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  90. Published

    Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice. / Gunnarsson, P Thomas; Winzell, Maria Sörhede; Deacon, Carolyn F; Larsen, Marianne O; Jelic, Katarina; Carr, Richard D; Ahrén, Bo.

    In: Endocrinology, Vol. 147, No. 7, 2006, p. 3173-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy. / Haugaard, S B; Andersen, O; Pedersen, S B; Dela, F; Deacon, C F; Holst, Jens Juul; Iversen, J; Madsbad, S.

    In: HIV Medicine, Vol. 7, No. 3, 2006, p. 163-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes—a review and meta analysis. / Deacon, Carolyn F.; Mannucci, E; Ahren, B.

    In: Diabetes, Obesity and Metabolism Online, Vol. 14, No. 8, 2012, p. 762-767.

    Research output: Contribution to journalReviewResearchpeer-review

  93. Published

    Human colon produces fully processed glucagon-like peptide-1 (7-36 amide). / Deacon, C.F.; Johnsen, A.H.; Holst, Jens Juul.

    In: FEBS Letters, No. 372, 1995, p. 269-272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA : nonspecific interference or truly elevated levels? / Albrechtsen, Nicolai Jacob Wewer; Hartmann, Bolette; Veedfald, Simon; Windeløv, Johanne A; Plamboeck, Astrid; Bojsen-Møller, Kirstine N; Idorn, Thomas; Feldt-Rasmussen, Bo; Knop, Filip K; Vilsbøll, Tina; Madsbad, Sten; Deacon, Carolyn F; Holst, Jens J.

    In: Diabetologia, Vol. 57, No. 9, 03.06.2014, p. 1919-1926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans. / Vollmer, Kirsten; Gardiwal, Husai; Menge, Bjoern A; Goetze, Oliver; Deacon, Carolyn F; Schmidt, Wolfgang E; Holst, Jens Juul; Meier, Juris J.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 4, 2009, p. 1379-85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men. / Veedfald, Simon; Wu, Tongzhi; Bound, Michelle; Grivell, Jacqueline; Hartmann, Bolette; Rehfeld, Jens F.; Deacon, Carolyn F.; Horowitz, Michael; Holst, Jens J.; Rayner, Christopher K.

    In: Journal of Clinical Endocrinology & Metabolism, Vol. 103, No. 12, 2018, p. 4409-4418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Immunoassays for the incretin hormones GIP and GLP-1. / Deacon, Carolyn F; Holst, Jens J.

    In: Best Practice & Research: Clinical Endocrinology & Metabolism, Vol. 23, No. 4, 2009, p. 425-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Impact of exogenous hyperglucagonemia on postprandial concentrations of gastric inhibitory polypeptide and glucagon-like peptide-1 in humans. / Meier, Juris J; Ritter, Peter R; Jacob, Alexandra; Menge, Bjoern A; Deacon, Carolyn F; Schmidt, Wolfgang E; Nauck, Michael A; Holst, Jens J.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 95, No. 8, 01.08.2010, p. 4061-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals. / Rohrer, Stefan; Menge, Björn A; Grüber, Lena; Deacon, Carolyn F; Schmidt, Wolfgang E; Veldhuis, Johannes D; Holst, Jens Juul; Meier, Juris J.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 5, 2012, p. E791-E795.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1. / Ugleholdt, Randi; Zhu, Xiaorong; Deacon, Carolyn F; Ørskov, Cathrine; Steiner, Donald F; Holst, Jens J.

    In: Endocrinology, Vol. 145, No. 3, 2003, p. 1349-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

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