Carolyn F. Deacon

Carolyn F. Deacon

Associate Professor


  1. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus. / Aaboe, K; Knop, F K; Vilsbøll, T; Deacon, C F; Holst, Jens Juul; Madsbad, S; Krarup, Troels Magelund.

    In: Diabetes, Obesity and Metabolism, Vol. 12, No. 4, 01.04.2010, p. 323-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors. / Aaboe, K.; Akram, S.; Deacon, C. F.; Holst, J. J.; Madsbad, S.; Krarup, T.

    In: Diabetes, Obesity and Metabolism, Vol. 17, No. 1, 01.2015, p. 74-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. Published
  5. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes. / Aaboe, Kasper; Knop, Filip Krag; Vilsboll, Tina; Vølund, Aage; Simonsen, Ulf; Deacon, Carolyn F.; Madsbad, Sten; Holst, Jens Juul; Krarup, Thure.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2008, p. 603-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes. / Aaboe, Kasper; Knop, Filip Krag; Vilsbøll, Tina; Vølund, A; Simonsen, U; Deacon, Carolyn F.; Madsbad, Sten; Holst, Jens Juul; Krarup, Thure.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2009, p. 603-608.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Incretin hormone secretion over the day. / Ahren, B; Carr, RD; Deacon, Carolyn F.

    In: Vitamins and Hormones, Vol. 84, 2010, p. 203-220.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production. / Albrechtsen, Nicolai J. Wewer; Kuhre, Rune E.; Hornburg, Daniel; Jensen, Christian Z.; Hornum, Mads; Dirksen, Carsten; Svane, Maria; Gasbjerg, Laerke S.; Jorgensen, Nils B.; Gabe, Maria N.; Balk-Moller, Emilie; Albrechtsen, Reidar; Winther-Sorensen, Marie; Galsgaard, Katrine D.; Meissner, Felix; Jorsal, Tina; Lund, Asger; Vilsboll, Tina; Eliasen, Rasmus; Bojsen-Moller, Kirstine N.; Idorn, Thomas; Deacon, Carolyn F.; Knop, Filip K.; Rosenkilde, Mette M.; Hartmann, Bolette; Feldt-Rasmussen, Bo; Mann, Matthias; Madsbad, Sten; Holst, Jens J.

    In: Cell Reports, Vol. 21, No. 6, 11.2017, p. 1452-1460.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Stability of glucagon-like peptide-1 and glucagon in human plasma. / Albrechtsen, Nicolai Jacob Wewer; Bak, Monika Judyta; Hartmann, Bolette; Christensen, Louise Wulff; Kuhre, Rune E; Deacon, Carolyn; Holst, Jens Juul.

    In: Endocrine Connections, Vol. 4, No. 1, 16.01.2015, p. 50-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Targeting the intestinal L-cell for obesity and type 2 diabetes treatment. / Albrechtsen, Nicolai Jacob Wewer; Kuhre, Rune Ehrenreich; Deacon, Carolyn F.; Holst, Jens Juul.

    In: Expert Review of Endocrinology & Metabolism, Vol. 9, No. 1, 01.01.2014, p. 61-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes. / Albrechtsen, Nicolai Jacob Wewer; Kuhre, Rune Ehrenreich; Windeløv, Johanne Agerlin; Ørgaard, Anne; Deacon, Carolyn F.; Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 311, No. 2, 2016, p. E302-E309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published
  13. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA : nonspecific interference or truly elevated levels? / Albrechtsen, Nicolai Jacob Wewer; Hartmann, Bolette; Veedfald, Simon; Windeløv, Johanne A; Plamboeck, Astrid; Bojsen-Møller, Kirstine N; Idorn, Thomas; Feldt-Rasmussen, Bo; Knop, Filip K; Vilsbøll, Tina; Madsbad, Sten; Deacon, Carolyn F; Holst, Jens J.

    In: Diabetologia, Vol. 57, No. 9, 03.06.2014, p. 1919-1926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes? / Andersen, Emilie S.; Lund, A.; Bagger, J. I.; Andreasen, C; Grøndahl, MF; Deacon, Carolyn F.; Hartmann, Bolette; Holst, Jens Juul; Knop, Filip Krag; Lauritsen, Tina Vilsbøll.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 8, 08.2018, p. 1937-1943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Do we know the true mechanism of action of the DPP-4 inhibitors? / Andersen, Emilie S.; Deacon, Carolyn F.; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 1, 2018, p. 34-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy. / Andersen, O; Haugaard, S B; Holst, Jens Juul; Deacon, C F; Iversen, J; Andersen, U B; Nielsen, J O; Madsbad, S.

    In: HIV Medicine, Vol. 6, No. 2, 03.2005, p. 91-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Enhanced glucagon-like peptide- 1 (GLP-1) response to oral glucose in glucose intolerant HIV-infected patients on antiretroviral therapy. / Andersen, O.; Haugaard, S.B.; Holst, Jens Juul; Deacon, Carolyn F.; Iversen, J.; Andersen, U.B.; Nielsen, J.O.; Madsbad, S.

    In: HIV Medicine, Vol. 6, 2005, p. 91-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes. / Asmar, Meena; Højberg, Patricia; Deacon, Carolyn F.; Hare, Kristine; Holst, Jens Juul; Madsbad, Sten.

    In: Regulatory Peptides, Vol. 160, No. 1-3, 2010, p. 175-180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes. / Asmar, Meena; Højberg, Patricia V; Deacon, Carolyn F; Hare, Kristine; Holst, Jens Juul; Madsbad, Sten.

    In: Regulatory Peptides, Vol. 160, No. 1-3, 2010, p. 175-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus. / Azuma, K; Radikova, Z; Mancino, J; Toledo, FGS; Thomas, E; Kangani, C; Dalla Man, C; Cobelli, C; Holst, Jens Juul; Deacon, Carolyn F.; He, Y; Ligueros-Saylan, M; Serra, D; Kelley, DE.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, 2008, p. 459-463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes. / Azuma, Koichiro; Rádiková, Zofia; Mancino, Juliet; Toledo, Frederico G S; Thomas, Ernestine; Kangani, Cyrous; Dalla Man, Chiara; Cobelli, Claudio; Holst, Jens J; Deacon, Carolyn F; He, Yanling; Ligueros-Saylan, Monica; Serra, Denise; Foley, James E; Kelley, David E.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 2, 2007, p. 459-464.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1) : Implications for GLP-1 measurements in clinical studies. / Bak, Monika Judyta; Albrechtsen, Nicolai Jacob Wewer; Pedersen, Jens; Knop, Filip Krag; Vilsbøll Lauritsen, Tina; Jørgensen, Nils B; Hartmann, Bolette; Deacon, Carolyn F.; Dragsted, Lars Ove; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism, Vol. 16, No. 11, 2014, p. 1155-1164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans. / Bak, Monika Judyta; Wewer Albrechtsen, Nicolai Jacob; Pedersen, Jens; Hartmann, Bolette; Christensen, Mikkel; Vilsbøll, Tina; Knop, Filip Krag; Deacon, Carolyn F; Dragsted, Lars Ove; Holst, Jens Juul.

    In: European Journal of Endocrinology, Vol. 170, No. 4, 2014, p. 529-538.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    No Effect of Aprotinin (Trasylol) on Degradation of Exogenous and Endogenous Glucagon in Human, Mouse and Rat Plasma. / Bak, Monika judyta; Albrechtsen, Nicolai Jacob Wewer; Hartmann, Bolette; Pedersen, Jens; Christensen, Mikkel; Vilsboll, Tina; Knop, Filip Krag; Deacon, Carolyn Fiona; Dragsted, Lars Ove; Holst, Jens Juul.

    In: Journal of Endocrinology and Diabetes, Vol. 1, No. 1, 2014, p. 1-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients. / Balas, Bogdan; Baig, Muhammad R; Watson, Catherine; Dunning, Beth E; Ligueros-Saylan, Monica; Wang, Yibin; He, Yan-Ling; Darland, Celia; Holst, Jens J; Deacon, Carolyn F; Cusi, Kenneth; Mari, Andrea; Foley, James E; DeFronzo, Ralph A.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 92, No. 4, 2007, p. 1249-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition : a randomized, prospective comparison of sitagliptin and vildagliptin treatment. / Baranov, Oleg; Kahle, Melanie; Deacon, Carolyn F; Holst, Jens J; Nauck, Michael A.

    In: Diabetes, Obesity and Metabolism, Vol. 18, No. 11, 11.2016, p. 1100-1109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose. / Bock, Gerlies; Man, Chiara Dalla; Micheletto, Francesco; Basu, Rita; Rn, Paula D Giesler; Laugen, Jeanette; Deacon, Carolyn F; Holst, Jens J; Toffolo, Gianna; Cobelli, Claudio; Rizza, Robert A; Vella, Adrian.

    In: Clinical Endocrinology, Vol. 73, 2010, p. 189-196.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men. / Carr, Richard D; Larsen, Marianne O; Jelic, Katarina; Lindgren, Ola; Vikman, Jenny; Holst, Jens J; Deacon, Carolyn F; Ahrén, Bo.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 95, No. 2, 2010, p. 872-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Incretin and islet hormonal responses to fat and protein ingestion in healthy men. / Carr, Richard D; Larsen, Marianne O; Winzell, Maria Sörhede; Jelic, Katarina; Lindgren, Ola; Deacon, Carolyn F; Ahrén, Bo.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 295, No. 4, 2008, p. E779-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice. / Christiansen, Charlotte B.; Lind, Sara J.; Svendsen, Berit; Balk-Møller, Emilie; Dahlby, Tina; Kuhre, Rune E; Hartmann, Bolette; Mandrup-Poulsen, Thomas; Deacon, Carolyn F; Albrechtsen, Nicolai J. Wewer; Holst, Jens J.

    In: Physiological Reports, Vol. 6, No. 13, e13788, 2018, p. 1-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure : A Pilot Study. / Clarke, Sophie J.; Pettit, Stephen; Giblett, Joel P.; Zhao, Tian; Kydd, Anna C.; Albrechtsen, Nicolai J. W.; Deacon, Carolyn F.; Parameshwar, Jayan; Hoole, Stephen P.

    In: Clinical Therapeutics, Vol. 41, No. 1, 2019, p. 118-127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    GLP-1 Is a Coronary Artery Vasodilator in Humans. / Clarke, Sophie J.; Giblett, Joel P.; Yang, Lucy L.; Hubsch, Annette; Zhao, Tian; Aetesam-ur-Rahman, Muhammad; West, Nick E. J.; O'Sullivan, Michael; Figg, Nichola; Bennett, Martin; Albrechtsen, Nicolai J. Wewer; Deacon, Carolyn F.; Cheriyan, Joseph; Hoole, Stephen P.

    In: Journal of the American Heart Association, Vol. 7, No. 22, e010321, 20.11.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass : A Case Report. / Craig, CM; Lamendola, C; Holst, Jens Juul; Deacon, Carolyn F.; McLaughlin, TL.

    In: aace clinical case reports, Vol. 1, No. 2, 2015, p. e84-e87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia. / Craig, Colleen M; Liu, Li-Fen; Deacon, Carolyn F; Holst, Jens J; McLaughlin, Tracey L.

    In: Diabetologia, Vol. 60, No. 3, 03.2017, p. 531-540.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs. / Deacon, C F; Wamberg, S; Bie, P; Hughes, T E; Holst, Jens Juul.

    In: Journal of Endocrinology, Vol. 172, No. 2, 02.2002, p. 355-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Glucagon-like peptide-1 : a basis for new approaches to the management of diabetes. / Deacon, C F; Holst, Jens Juul; Carr, R D.

    In: Drugs of Today, Vol. 35, No. 3, 03.1999, p. 159-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide. / Deacon, C.F.; Nauck, M.A.; Meier, J.; Hücking, K.; Holst, J.J.

    In: Journal of Clinical Endocrinology and Metabolism, No. 85, 2000, p. 3575-3581.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Human colon produces fully processed glucagon-like peptide-1 (7-36 amide). / Deacon, C.F.; Johnsen, A.H.; Holst, Jens Juul.

    In: FEBS Letters, No. 372, 1995, p. 269-272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo. / Deacon, C.F.; Johnsen, A.H.; Holst, Jens Juul.

    In: Journal of Clinical Endocrinology and Metabolism, No. 80, 1995, p. 952-957.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity. / Deacon, C.F.; Knudsen, L.B.; Madsen, K.; Wiberg, F.C.; Jacobsen, O.; Holst, J.J.

    In: Diabetologia, No. 41, 1998, p. 271-278.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects. / Deacon, C.F.; Nauck, M.A.; Nielsen, M.T.; Pridal, L.; Holst, Jens Juul.

    In: Diabetes, No. 44, 1995, p. 1126-1131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs. / Deacon, C.F.; Danielsen, P.; Klarskov, L.; Holst, J.J.; Olesen, M.

    In: Diabetes, No. 50, 2001, p. 1588-1597.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig. / Deacon, C.F.; Hughes, T.E.; Holst, J.J.

    In: Diabetes, No. 47, 1998, p. 764-769.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Glucagon-like peptide-1: A basis for new approaches to the management of Diabetes. / Deacon, C.F.; Holst, J.J.; Carr, R.D.

    In: Drugs of Today, No. 35, 1999, p. 159-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    What do we know about the secretion and degradation of incretin hormones? / Deacon, Carolyn F.

    In: Regulatory Peptides, Vol. 128, No. 2, 2005, p. 117-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes : comparison, efficacy and safety. / Deacon, Carolyn F; Holst, Jens Juul.

    In: Expert Opinion on Pharmacotherapy, Vol. 14, No. 15, 10.2013, p. 2047-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Inhibitors of dipeptidyl peptidase IV: a novel approach for the prevention and treatment of Type 2 diabetes? / Deacon, Carolyn F; Ahrén, Bo; Holst, Jens J.

    In: Expert Opinion on Investigational Drugs, Vol. 13, No. 9, 2004, p. 1091-102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes. / Deacon, Carolyn F; Carr, Richard D; Holst, Jens Juul.

    In: Frontiers in Bioscience, Vol. 13, 2008, p. 1780-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Differential regional metabolism of glucagon in anesthetized pigs. / Deacon, Carolyn F; Kelstrup, Mette; Trebbien, Ramona; Klarskov, Letty; Olesen, Mette; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 285, No. 3, 2003, p. E552-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Incretin-based treatment of type 2 diabetes: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 9 Suppl 1, 2007, p. 23-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes. / Deacon, Carolyn F; Holst, Jens J.

    In: International Journal of Biochemistry & Cell Biology, Vol. 38, No. 5-6, 2005, p. 831-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    A review of dipeptidyl peptidase-4 inhibitors : Hot topics from randomized controlled trials. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 20, 02.2018, p. 34-46.

    Research output: Contribution to journalReviewResearchpeer-review

  53. Published

    Peptide degradation and the role of DPP-4 inhibitors in the treatment of type 2 diabetes. / Deacon, Carolyn F.

    In: Peptides, Vol. 100, 02.2018, p. 150-157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. / Deacon, Carolyn F; Holst, Jens J.

    In: Advances in Therapy, Vol. 26, No. 5, 2009, p. 488-99.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion. / Deacon, Carolyn F; Plamboeck, Astrid; Møller, Søren; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 282, No. 4, 2002, p. E873-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations. / Deacon, Carolyn F; Plamboeck, Astrid; Rosenkilde, Mette M; de Heer, Jocelyn; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 291, No. 3, 2006, p. E468-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes. / Deacon, Carolyn F.

    In: Current Opinion in Investigational Drugs, Vol. 9, No. 4, 2008, p. 402-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Therapeutic strategies based on glucagon-like peptide 1. / Deacon, Carolyn F.

    In: Diabetes, Vol. 53, No. 9, 2004, p. 2181-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective. / Deacon, Carolyn F; Holst, Jens J.

    In: Biochemical and Biophysical Research Communications, Vol. 294, No. 1, 2002, p. 1-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Potential of liraglutide in the treatment of patients with type 2 diabetes. / Deacon, Carolyn F.

    In: Vascular Health and Risk Management (Online), Vol. 5, No. 1, 2009, p. 199-211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    MK-431 (Merck). / Deacon, Carolyn F.

    In: Current Opinion in Investigational Drugs, Vol. 6, No. 4, 2005, p. 419-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Immunoassays for the incretin hormones GIP and GLP-1. / Deacon, Carolyn F; Holst, Jens J.

    In: Best Practice & Research: Clinical Endocrinology & Metabolism, Vol. 23, No. 4, 2009, p. 425-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Dipeptidyl peptidase 4 inhibition with sitagliptin: a new therapy for type 2 diabetes. / Deacon, Carolyn F.

    In: Expert Opinion on Investigational Drugs, Vol. 16, No. 4, 2007, p. 533-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes. / Deacon, Carolyn F; Holst, Jens Juul.

    In: Expert Opinion on Investigational Drugs, Vol. 19, No. 1, 01.2010, p. 133-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 1, 01.2011, p. 7-18.

    Research output: Contribution to journalReviewResearchpeer-review

  66. Published

    Commentary: Is endogenous GLP-1 the only important enhancer of glucose-induced insulin secretion in type 2 diabetes? / Deacon, Carolyn F.

    In: Diabetes, Vol. 61, No. 9, 2012, p. 2219-2220.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Physiology of incretins in health and disease. / Deacon, Carolyn F.; Ahren, Bo.

    In: Review of Diabetic Studies, Vol. 8, No. 3, 2011, p. 293-306.

    Research output: Contribution to journalReviewResearchpeer-review

  68. Published

    DPP-4 inhibition – advances in our understanding of diabetes management. / Deacon, Carolyn F.; Holst, Jens Juul.

    In: European Endocrinology, Vol. 4, 2009, p. 47-49.

    Research output: Contribution to journalReviewResearch

  69. Published

    Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes. / Deacon, Carolyn F.

    In: Frontiers in Endocrinology, Vol. 10, 80, 2019.

    Research output: Contribution to journalReviewResearchpeer-review

  70. Published

    Potential cardiovascular effects of incretin-based therapies. / Deacon, Carolyn F.; Marx, N.

    In: Expert Review of Cardiovascular Therapy, Vol. 10, 2012, p. 337-351.

    Research output: Contribution to journalReviewResearchpeer-review

  71. Published

    Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas. / Deacon, Carolyn F.; Lebovitz, HE.

    In: Diabetes, Obesity and Metabolism, Vol. 18, No. 4, 2016, p. 333-347.

    Research output: Contribution to journalReviewResearchpeer-review

  72. Published

    A comparative review of DPP-4 inhibitors and sulphonylureas. / Deacon, Carolyn F.; Lebovitz, HE.

    In: Diabetes, Obesity and Metabolism, Vol. 18, 2016, p. 333-347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Circulation and degradation of GIP and GLP-1. / Deacon, Carolyn F.

    In: Hormone and Metabolic Research, No. 36, 2004, p. 761-765.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes—a review and meta analysis. / Deacon, Carolyn F.; Mannucci, E; Ahren, B.

    In: Diabetes, Obesity and Metabolism Online, Vol. 14, No. 8, 2012, p. 762-767.

    Research output: Contribution to journalReviewResearchpeer-review

  75. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes. / Deacon, Carolyn F.; Holst, Jens Juul.

    In: Expert Opinion on Investigational Drugs, Vol. 19, No. 1, 2010, p. 133-140.

    Research output: Contribution to journalReviewResearchpeer-review

  76. Published

    DPP-4 inhibitors. / Deacon, Carolyn F.

    Handbook of incretin therapies in type 2 diabetes. ed. / S Gough. Switzerland : Springer, 2016. p. 45-60.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  77. Published

    A review of dipeptidyl peptidase-4 inhibitors. Hot topics from randomised controlled trials. / Deacon, Carolyn F.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. Suppl. 1, 2018, p. 34-46.

    Research output: Contribution to journalReviewResearchpeer-review

  78. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men. / Eelderink, Coby; Noort, Martijn W J; Sozer, Nesli; Koehorst, Martijn; Holst, Jens J; Deacon, Carolyn F; Rehfeld, Jens F; Poutanen, Kaisa; Vonk, Roel J; Oudhuis, Lizette; Priebe, Marion G.

    In: European Journal of Nutrition, Vol. 56, No. 3, 2017, p. 1063-1076.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    The structure of wheat bread influences the postprandial metabolic response in healthy men. / Eelderink, Coby; Noort, Martijn W J; Sozer, Nesli; Koehorst, Martijn; Holst, Jens J; Deacon, Carolyn F; Rehfeld, Jens F; Poutanen, Kaisa; Vonk, Roel J; Oudhuis, Lizette; Priebe, Marion G.

    In: Food & Function, Vol. 6, No. 10, 10.2015, p. 3236-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes. / Foley, J E; Ligueros-Saylan, M; He, Y-L; Holst, Jens Juul; Deacon, C F; Dunning, B E; Leone-Jones, A; Yu, T; Kelley, D E.

    In: Hormone and Metabolic Research. Supplement, Vol. 40, No. 10, 10.2008, p. 727-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes. / Foley, J.E.; Ligueros-Saylan, M.; He, Y.L.; Holst, Jens Juul; Deacon, Carolyn F.; Dunning, B.E.; Leone-Jones, A.; Yu, T.; Kelley, D.E.

    In: Hormone and Metabolic Research, Vol. 40, No. 10, 2008, p. 727-730.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published
  83. Published

    Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV. / Gram, Dorte X; Hansen, Anker J; Deacon, Carolyn F; Brand, Christian L; Ribel, Ulla; Wilken, Michael; Carr, Richard D; Svendsen, Ove; Ahrén, Bo.

    In: European Journal of Pharmacology, Vol. 509, No. 2-3, 2005, p. 211-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice. / Gunnarsson, P Thomas; Winzell, Maria Sörhede; Deacon, Carolyn F; Larsen, Marianne O; Jelic, Katarina; Carr, Richard D; Ahrén, Bo.

    In: Endocrinology, Vol. 147, No. 7, 2006, p. 3173-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. / Hansen, L; Deacon, C F; Orskov, C; Holst, J J.

    In: Molecular Endocrinology, Vol. 140, No. 11, 11.1999, p. 5356-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells. / Hansen, L.; Deacon, C.F.; Ørskov, C.; Holst, J.J.

    In: Endokrinologiya, No. 140, 1999, p. 5356-5363.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV. / Hansen, Lene; Hare, Kristine J; Hartmann, Bolette; Deacon, Carolyn F; Ugleholdt, Randi K; Plamboeck, Astrid; Holst, Jens J.

    In: Regulatory Peptides, Vol. 138, No. 2-3, 2006, p. 126-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Important species differences regarding lymph contribution to gut hormone responses. / Hansen, Marie; Hjøllund, Karina R; Hartmann, Bolette; Plamboeck, Astrid; Deacon, Carolyn F; Albrechtsen, Nicolai Jacob Wewer; Holst, Jens J.

    In: Peptides, Vol. 71, 09.2015, p. 28-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus. / Hare, Kristine J; Knop, Filip K; Asmar, Meena; Madsbad, Sten; Deacon, Carolyn F; Holst, Jens J; Vilsbøll, Tina.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 12, 2009, p. 4679-87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action. / Hare, Kristine J; Vilsbøll, Tina; Asmar, Meena; Deacon, Carolyn F; Knop, Filip K; Holst, Jens Juul.

    In: Diabetes, Vol. 59, No. 7, 01.07.2010, p. 1765-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    In vivo and in vitro degradation of glucagon-like peptide-2 in humans. / Hartmann, Bolette; Harr, M.B.; Jeppesen, P.B.; Wojdemann, M.; Deacon, C.F.; Mortensen, P.B.; Holst, J.J.

    In: Journal of Clinical Endocrinology and Metabolism, No. 85, 2000, p. 2884-2888.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy. / Haugaard, S B; Andersen, O; Pedersen, S B; Dela, F; Deacon, C F; Holst, Jens Juul; Iversen, J; Madsbad, S.

    In: HIV Medicine, Vol. 7, No. 3, 2006, p. 163-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Plasma TNF-x is associated with insulin mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy. / Haugaard, S.B.; Andersen, O.; Pedersen, S.B.; Dela, Flemming; Deacon, C.F.

    In: Metabolism - Clinical and Experimental, No. 55(2), 1996, p. 175-182.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT. / He, Yan-Ling; Wang, Yibin; Bullock, Julie M; Deacon, Carolyn F; Holst, Jens Juul; Dunning, Beth E; Ligueros-Saylan, Monica; Foley, James E.

    In: Journal of Clinical Pharmacology, Vol. 47, No. 5, 2007, p. 633-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus. / He, Yan-Ling; Serra, Denise; Wang, Yibin; Campestrini, Joelle; Riviere, Gilles-Jacques; Deacon, Carolyn F; Holst, Jens J; Schwartz, Sherwyn; Nielsen, Jace C; Ligueros-Saylan, Monica.

    In: Clinical Pharmacokinetics, Vol. 46, No. 7, 2007, p. 577-88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes. / Henry, R R; Smith, Susanne; Schwartz, Saul; Mudaliar, S R; Deacon, C F; Holst, Jens Juul; Duan, R Y; Chen, R S; List, J F.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 9, 2011, p. 850-858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes. / Herman, Gary A; Bergman, Arthur; Stevens, Catherine; Kotey, Paul; Yi, Bingming; Zhao, Peng; Dietrich, Bruno; Golor, George; Schrodter, Andreas; Keymeulen, Bart; Lasseter, Kenneth C; Kipnes, Mark S; Snyder, Karen; Hilliard, Deborah; Tanen, Michael; Cilissen, Caroline; De Smet, Marina; de Lepeleire, Inge; Van Dyck, Kristien; Wang, Amy Q; Zeng, Wei; Davies, Michael J; Tanaka, Wesley; Holst, Jens J; Deacon, Carolyn F; Gottesdiener, Keith M; Wagner, John A.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 91, No. 11, 2006, p. 4612-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Effects of the dipeptidyl peptidase IV inhibitor, vildagliptin, on glycemic, gut hormone, triglyceride, energy expenditure and energy intake responses to intraduodenal fat infusion in healthy males. / Heruc, GA; Horowitz, Michael; Deacon, Carolyn F.; Feinle-Bisset, C; Rayner, CK; Luscombe-Marsh, N; Little, Tanya J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 307, No. 9, 2014, p. E830-E837.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs. / Hjøllund, K R; Deacon, C F; Holst, Jens Juul.

    In: Diabetologia, Vol. 54, No. 8, 2011, p. 2206-8.

    Research output: Contribution to journalLetterResearchpeer-review

  100. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1. / Holst, J.J.; Deacon, C.F.; Toft-Nielsen, M.; Bjerre-Knudsen, L.

    In: Annals of the New York Academy of Sciences, No. 865, 1998, p. 336-343.

    Research output: Contribution to journalJournal articleResearchpeer-review

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