Carolyn F. Deacon
Associate Professor
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Effects of sitagliptin on glycemia, incretin hormones, and antropyloroduodenal motility in response to intraduodenal glucose infusion in healthy lean and obese humans, and patients with type 2 diabetes treated with or without metformin
Wu, T., Ma, J., Bound, M., Checklin, H., Deacon, Carolyn F., Jones, K., Horowitz, M. & Raynor, C., 2014, In: Diabetes. 63, 8, p. 2776-2787 12 p.Research output: Contribution to journal › Journal article › peer-review
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Effects of sitagliptin on blood pressure and heart rate in response to intraduodenal glucose infusion in type 2 diabetes
Wu, T., Trahair, L., Bound, M., Deacon, Carolyn F., Horowitz, M., Rayner, C. & Jones, K., 2015, In: Diabetic Medicine. 32, 5, p. 595-600 6 p.Research output: Contribution to journal › Journal article › peer-review
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Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose
Vardarli, I., Arndt, E., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Feb 2014, In: Diabetes. 63, 2, p. 663-74 12 p.Research output: Contribution to journal › Journal article › peer-review
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Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus
Stephens, J. W., Bodvarsdottir, T. B., Wareham, K., Prior, S. L., Bracken, R. M., Lowe, G. D., Rumley, A., Dunseath, G., Luzio, S., Deacon, Carolyn F., Holst, Jens Juul & Bain, S. C., Nov 2011, In: Diabetes Research and Clinical Practice. 94, 2, p. 199-206 8 p.Research output: Contribution to journal › Journal article › peer-review
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Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes
Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In: Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.Research output: Contribution to journal › Journal article › peer-review
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Effects of a six-week intervention with glucagon-like peptide-1 receptor analogue on pancreatic volume, oedema and DNA synthesis in obese men
Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, A. E., Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S216-S217 442.Research output: Contribution to journal › Conference abstract in journal
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Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes
Tharp, W. G., Gupta, D., Sideleva, O., Deacon, Carolyn F., Holst, Jens Juul, Elahi, D. & Pratley, R. E., 2020, In: Diabetes. 69, 2, p. 146-157Research output: Contribution to journal › Journal article › peer-review
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Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study
Clarke, S. J., Pettit, S., Giblett, J. P., Zhao, T., Kydd, A. C., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Parameshwar, J. & Hoole, S. P., 2019, In: Clinical Therapeutics. 41, 1, p. 118-127 10 p.Research output: Contribution to journal › Journal article › peer-review
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Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes
Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In: Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.Research output: Contribution to journal › Journal article › peer-review
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Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.
Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q. & 7 others, , 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.Research output: Contribution to journal › Journal article › peer-review
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Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes
Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In: Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.Research output: Contribution to journal › Journal article › peer-review
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Effect of Sitagliptin therapy on postprandial lipoprotein levels in patients with type 2 diabetes
Tremblay, A., Lamarche, B., Deacon, Carolyn F., Weisnagel, S. & Couture, P., Apr 2011, In: Diabetes, Obesity and Metabolism. 13, 4, p. 366-373 8 p.Research output: Contribution to journal › Journal article › peer-review
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Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients
Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.Research output: Contribution to journal › Journal article › peer-review
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Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.Research output: Contribution to journal › Journal article › peer-review
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Do we know the true mechanism of action of the DPP-4 inhibitors?
Andersen, E. S., Deacon, Carolyn F. & Holst, Jens Juul, 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 34-41 8 p.Research output: Contribution to journal › Journal article › peer-review
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Do sodium-glucose transporter-2 inhibitors increase plasma glucagon by direct actions on the alpha-cell? - and does the increase matter for the associated increase in endogenous glucose production?
Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2021, In: Diabetes, Obesity and Metabolism. 23, 9, p. 2009-2019Research output: Contribution to journal › Review › peer-review
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Dissociated incretin hormone response to protein versus fat ingestion in obese subjects
Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In: Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review
Deacon, Carolyn F., Jan 2011, In: Diabetes, Obesity and Metabolism. 13, 1, p. 7-18 12 p.Research output: Contribution to journal › Review › peer-review
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Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety
Deacon, Carolyn F. & Holst, Jens Juul, Oct 2013, In: Expert Opinion on Pharmacotherapy. 14, 15, p. 2047-58 12 p.Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1
Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, , 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs
Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.Research output: Contribution to journal › Letter › peer-review
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Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity
Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes.
Deacon, Carolyn F. & Holst, Jens Juul, 2005, In: International Journal of Biochemistry & Cell Biology. 38, 5-6, p. 831-44 13 p.Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs
Deacon, Carolyn F., Danielsen, P., Klarskov, L., Holst, Jens Juul & Olesen, M., 2001, In: Diabetes. 50, p. 1588-1597Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.
Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769Research output: Contribution to journal › Journal article › peer-review
ID: 9220
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388
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Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
Research output: Contribution to journal › Journal article › peer-review
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305
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Acute effects of dietary carbohydrate restriction on glycemia, lipemia and appetite regulating hormones in normal-weight to obese subjects
Research output: Contribution to journal › Journal article › peer-review
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297
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › peer-review
Published