Carolyn F. Deacon

Carolyn F. Deacon

Associate Professor

Member of:

    ORCID: 0000-0003-2611-5642

    Publication year:
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    1 - 238 out of 238Page size: 500
    1. 2024
    2. Published

      Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes

      Hartmann, Bolette, Longo, M., Mathiesen, D. S., Hare, Kristine Juul, Jørgensen, Niklas Rye, Esposito, K., Deacon, Carolyn F., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 1, p. e259-e265 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2023
    4. Published

      Impact of dipeptidyl peptidase-4 inhibitors on glucose-dependent insulinotropic polypeptide in type 2 diabetes mellitus: a systematic review and meta-analysis

      Chai, S., Zhang, R., Carr, R. D., Deacon, Carolyn F., Zheng, Y., Rajpathak, S., Chen, J. & Yu, M., 2023, In: Frontiers in Endocrinology. 14, 12 p., 1203187.

      Research output: Contribution to journal › Review › Research › peer-review

    5. 2022
    6. Published

      Acute effects of linagliptin on intact and total glucagon-like peptide-1 and gastric inhibitory polypeptide levels in insulin-dependent type 2 diabetes patients with and without moderate renal impairment

      Meier, J. J., Quast, D. R., Nauck, M. A., Schenker, N., Deacon, Carolyn F., Holst, Jens Juul, Plum-Mörschel, L. & Kapitza, C., 2022, In: Diabetes, Obesity and Metabolism. 24, 5, p. 806-815

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes

      Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Four weeks treatment with the GLP-1 receptor analogue liraglutide lowers liver fat and concomitantly circulating glucagon in individuals with overweight

      Svane, M. S., Johannesen, H. H., Hansen, Adam Espe, Martinussen, C., Bojsen-Møller, K. N., Hansen, M. L., Deacon, Carolyn F., Keller, S. H., Klausen, Thomas Levin, Loft, A., Kjær, Andreas, Löfgren, J., Madsbad, Sten, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: International Journal of Obesity. 46, 11, p. 2058–2062 8 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    9. Published

      Measurement of plasma glucagon in humans: A shift in the performance of a current commercially available radioimmunoassay kit

      Wu, T., Rayner, C. K., Jones, K. L., Horowitz, M., Feinle-Bisset, C., Standfield, S. D., Xie, C., Deacon, Carolyn F., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1182-1184

      Research output: Contribution to journal › Letter › Research › peer-review

    10. Published

      Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty

      Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism

      Taskinen, M., Matikainen, N., Björnson, E., Söderlund, S., Ainola, M., Hakkarainen, A., Lundbom, N., Sihlbom, C., Thorsell, A., Andersson, L., Adiels, M., Hartmann, Bolette, Deacon, Carolyn F., Holst, Jens Juul, Packard, C. J. & Borén, J., 2022, In: European Journal of Endocrinology. 187, 1, p. 75-84 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. 2021
    13. Published

      Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner

      Jepsen, Sara Lind, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Farb, T. B., Kissow, Hannelouise, Pedersen, J., Deacon, Carolyn F., Martin, R. E. & Holst, Jens Juul, 2021, In: JCI insight. 6, 4, 15 p., e143228.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Cerebral effects of glucagon-like peptide-1 receptor blockade before and after Roux-en-Y gastric bypass surgery in obese women: A proof-of-concept resting-state functional MRI study

      van Duinkerken, E., Bernardes, G., van Bloemendaal, L., Veltman, D. J., Barkhof, F., Mograbi, D. C., Gerdes, V. E. A., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M., ten Kulve, J. & Ijzerman, R. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 415-424 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Do sodium-glucose transporter-2 inhibitors increase plasma glucagon by direct actions on the alpha-cell? - and does the increase matter for the associated increase in endogenous glucose production?

      Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2021, In: Diabetes, Obesity and Metabolism. 23, 9, p. 2009-2019

      Research output: Contribution to journal › Review › Research › peer-review

    16. Published

      Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

      Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell?

      Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Holst, Jens Juul & Petersen, N., 2021, In: Frontiers in Endocrinology. 12, 19 p., 694284.

      Research output: Contribution to journal › Review › Research › peer-review

    18. 2020
    19. Published

      Dipeptidyl peptidase 4 inhibitors in the treatment of type 2 diabetes mellitus

      Deacon, Carolyn F., 2020, In: Nature Reviews Endocrinology. 16, 11, p. 642-653

      Research output: Contribution to journal › Review › Research › peer-review

    20. Published

      Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes

      Tharp, W. G., Gupta, D., Sideleva, O., Deacon, Carolyn F., Holst, Jens Juul, Elahi, D. & Pratley, R. E., 2020, In: Diabetes. 69, 2, p. 146-157

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Effects of a six-week intervention with glucagon-like peptide-1 receptor analogue on pancreatic volume, oedema and DNA synthesis in obese men

      Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, A. E., Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S216-S217 442.

      Research output: Contribution to journal › Conference abstract in journal › Research

    22. Published

      Glucose-Dependent Insulinotropic Polypeptide Is a Pancreatic Polypeptide Secretagogue in Humans

      Veedfald, Simon, Vedtofte, L., Skov-Jeppesen, Kirsa, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Christensen, Mikkel Bring & Holst, Jens Juul, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e502-e510

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Metabolism of GIP and the contribution of GIP to the glucose-lowering properties of DPP-4 inhibitors

      Deacon, Carolyn F., 2020, In: Peptides. 125, 7 p., 170196.

      Research output: Contribution to journal › Review › Research › peer-review

    24. Published

      No effects of a 6-week intervention with a glucagon-like peptide-1 receptor agonist on pancreatic volume and oedema in obese men without diabetes

      Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, Adam Espe, Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Klausen, T. L., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetes, Obesity and Metabolism. 22, 10, p. 1837-1846

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects

      Nauck, M. A., Holle, H., Kahle, M., Tytko, A., Deacon, Carolyn F., Holst, Jens Juul & Meier, J. J., 2020, In: Peptides. 125, 170176.

      Research output: Contribution to journal › Review › Research › peer-review

    26. Published

      The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study

      Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. 2019
    28. Published

      Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study

      Clarke, S. J., Pettit, S., Giblett, J. P., Zhao, T., Kydd, A. C., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Parameshwar, J. & Hoole, S. P., 2019, In: Clinical Therapeutics. 41, 1, p. 118-127 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice

      Jepsen, Sara Lind, Grunddal, Kaare Villum, Albrechtsen, Nicolai Jacob Wewer, Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, Cathrine, Poulsen, Steen Seier, Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, Carolyn F., Schwartz, Thue W., Christ, A. D., Martin, R. E. & Holst, Jens Juul, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 6, p. E1081-E1093

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes

      Deacon, Carolyn F., 2019, In: Frontiers in Endocrinology. 10, 14 p., 80.

      Research output: Contribution to journal › Review › Research › peer-review

    31. Published

      Physiology of the Incretin Hormones, GIP and GLP-1-Regulation of Release and Posttranslational Modifications

      Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Rosenkilde, Mette & Deacon, Carolyn F., 2019, In: Comprehensive Physiology. 9, 4, p. 1339-1381

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Sacubitril/Valsartan Augments Postprandial Plasma Concentrations of Active GLP-1 When Combined With Sitagliptin in Men

      Albrechtsen, Nicolai Jacob Wewer, Mark, P. D., Terzic, D., Hansen, L. H., Andersen, U. Ø., Hartmann, Bolette, Carr, R. D., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Goetze, Jens P. & Plomgaard, Peter Stendahl, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 9, p. 3868-3876

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. 2018
    34. Published

      GLP-1 Is a Coronary Artery Vasodilator in Humans

      Clarke, S. J., Giblett, J. P., Yang, L. L., Hubsch, A., Zhao, T., Aetesam-ur-Rahman, M., West, N. E. J., O'Sullivan, M., Figg, N., Bennett, M., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Cheriyan, J. & Hoole, S. P., 20 Nov 2018, In: Journal of the American Heart Association. 7, 22, 14 p., e010321.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?

      Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M., Deacon, Carolyn F., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Aug 2018, In: Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Ghrelin secretion in humans - a role for the vagus nerve?

      Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F., Svendsen, Lars Bo & Holst, Jens Juul, Jun 2018, In: Neurogastroenterology and Motility. 30, 6, e13295.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      A review of dipeptidyl peptidase-4 inhibitors: Hot topics from randomized controlled trials

      Deacon, Carolyn F., Feb 2018, In: Diabetes, Obesity and Metabolism. 20, p. 34-46 13 p.

      Research output: Contribution to journal › Review › Research › peer-review

    38. Published

      Peptide degradation and the role of DPP-4 inhibitors in the treatment of type 2 diabetes

      Deacon, Carolyn F., Feb 2018, In: Peptides. 100, p. 150-157 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients

      Samkani, A., fbg982, fbg982, Kandel, D., Kjaer, S., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2018, In: British Journal of Nutrition. 119, 8, p. 910-917 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      A review of dipeptidyl peptidase-4 inhibitors. Hot topics from randomised controlled trials

      Deacon, Carolyn F., 2018, In: Diabetes, Obesity and Metabolism. 20, Suppl. 1, p. 34-46

      Research output: Contribution to journal › Review › Research › peer-review

    41. Published

      Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

      Christiansen, Charlotte Bayer, Jepsen, Sara Lind, Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, Rune Ehrenreich, Hartmann, Bolette, Mandrup-Poulsen, Thomas, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Acute effects of dietary carbohydrate restriction on glycemia, lipemia and appetite regulating hormones in normal-weight to obese subjects

      Samkani, A. A., fbg982, fbg982, Thomsen, M. N., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Krarup, T. & Haugaard, Steen Bendix, 2018, In: Nutrients. 10, 9, 14 p., 1285.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

      Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Larsen, Olav, Jepsen, Sara Lind, Balk-Møller, E., Andersen, Daniel Bjørklund, Deacon, Carolyn F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, Reidar, Hartmann, Bolette, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: Molecular Metabolism. 11, p. 84-95 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Do we know the true mechanism of action of the DPP-4 inhibitors?

      Andersen, E. S., Deacon, Carolyn F. & Holst, Jens Juul, 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 34-41 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men

      Veedfald, Simon, Wu, T., Bound, M., Grivell, J., Hartmann, Bolette, Rehfeld, Jens Frederik, Deacon, Carolyn F., Horowitz, M., Holst, Jens Juul & Rayner, C. K., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 12, p. 4409-4418

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial

      Samkani, A., fbg982, fbg982, Anholm, C., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S., Boston, R., Krarup, T. & Haugaard, Steen Bendix, 2018, In: Lipids in Health and Disease. 17, 9 p., 295.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. 2017
    48. Published

      Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

      Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Elevated Postoperative Endogenous GLP-1 Levels Mediate Effects of Roux-en-Y Gastric Bypass on Neural Responsivity to Food Cues

      Ten Kulve, J. S., Veltman, D. J., Gerdes, V. E. A., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M. & IJzerman, R. G., Nov 2017, In: Diabetes Care. 40, 11, p. 1522-1529 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

      Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

      Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men

      Matikainen, N., Söderlund, S., Björnson, E., Bogl, L. H., Pietiläinen, K. H., Hakkarainen, A., Lundbom, N., Eliasson, B., Räsänen, S. M., Rivellese, A., Patti, L., Prinster, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., Jun 2017, In: Nutrition, Metabolism & Cardiovascular Diseases. 27, 6, p. 534-542 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia

      Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide: A randomized controlled trial in patients with type 2 diabetes

      Nauck, M. A., Kahle, M., Baranov, O., Deacon, Carolyn F. & Holst, Jens Juul, 6 Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 200-207 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men

      Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In: European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. 2016
    57. Published

      Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition: a randomized, prospective comparison of sitagliptin and vildagliptin treatment

      Baranov, O., Kahle, M., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Nov 2016, In: Diabetes, Obesity and Metabolism. 18, 11, p. 1100-1109 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

      Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      The insulinotropic effect of exogenous GLP-1 is not affected by acute vagotomy in anaesthetized pigs

      Veedfald, Simon, Hansen, M., Christensen, L. W., Larsen, S. A. H., Hjøllund, K. R., Plamboeck, A., Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, 30 Mar 2016, In: Experimental Physiology. 101, 7, p. 895-912 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Cephalic phase secretion of insulin and other enteropancreatic hormones in humans

      Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      A Protein Preload Enhances the Glucose-Lowering Efficacy of Vildagliptin in Type 2 Diabetes

      Wu, T., Little, T., Bound, M., Borg, M., Zhang, X., Deacon, Carolyn F., Horowitz, M., Jones, K. & Rayner, C., 2016, In: Diabetes Care. 39, 4, p. 511-517 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      A comparative review of DPP-4 inhibitors and sulphonylureas

      Deacon, Carolyn F. & Lebovitz, H., 2016, In: Diabetes, Obesity and Metabolism. 18, p. 333-347

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas.

      Deacon, Carolyn F. & Lebovitz, H., 2016, In: Diabetes, Obesity and Metabolism. 18, 4, p. 333-347 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    64. Published

      DPP-4 inhibitors

      Deacon, Carolyn F., 2016, Handbook of incretin therapies in type 2 diabetes. Gough, S. (ed.). Switzerland: Springer, p. 45-60

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

    65. Published

      Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.

      Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes

      Albrechtsen, Nicolai Jacob Wewer, Albrechtsen, Reidar, Bremholm, L., Svendsen, B., Kuhre, Rune Ehrenreich, Poulsen, Steen Seier, Christiansen, Charlotte Bayer, Jensen, E. P., Janus, C., Hilsted, Linda, Deacon, Carolyn F., Hartmann, Bolette & Holst, Jens Juul, 2016, In: Cell Reports. 17, 11, p. 2845-2856 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Published

      Inability of Some Commercial Assays to Measure Suppression of Glucagon Secretion

      Albrechtsen, Nicolai Jacob Wewer, Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2016, In: Journal of Diabetes Research. 2016, 5 p., 8352957.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men

      Matikainen, N., Björnson, E., Söderlund, S., Borén, C., Eliasson, B., Pietiläinen, K. H., Bogl, L. H., Hakkarainen, A., Lundbom, N., Rivellese, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., 2016, In: PLOS ONE. 11, 1, p. 1-15 15 p., e0145890.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Pancreatic α-cell hyperplasia and hyperglucagonemia due to a mutation of the glucagon

      Larger, E., Albrechtsen, Nicolai Jacob Wewer, Hansen, L. H., Gelling, R. W., Capeau, J., Deacon, Carolyn F., Madsen, O. D., Yakushiji, F., Meyts, P. D., Holst, Jens Juul & Nishimura, E., 2016, In: Endocrinology, Diabetes & Metabolism Case Reports. 2016, 6 p., EDM160081.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Peptide production and secretion in GLUTag, NCI-H716 and STC-1 cells: a comparison to native L-cells.

      Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Balk-Møller, E., Rehfeld, Jens Frederik, Relman, F., Gribble, F. M. & Holst, Jens Juul, 2016, In: Journal of Molecular Endocrinology. 56, p. 201-211

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and type 2-diabetic patients using exendin [9-39] as a GLP-1 receptor antagonist.

      Nauck, M. A., Kind, J., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Broschag, M., He, Y., Kjems, L. & Foley, J., 2016, In: Diabetes. 65, 8, p. 2440-2447 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      Small intestinal glucose delivery affects the glucose-lowering effect of acute vildagliptin in type 2 diabetes

      Wu, T., Zhang, X., Trahair, L., Bound, M., Little, T., Deacon, Carolyn F., Horowitz, M., Jones, K. & Rayner, C., 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 12, p. 4769-4778

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. 2015
    74. Published

      Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes

      Ten Kulve, J. S., Veltman, D. J., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Konrad, R. J., Sloan, J. H., Drent, M. L., Diamant, M. & IJzerman, R. G., Dec 2015, In: Diabetologia. 58, 12, p. 2688-98 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      The structure of wheat bread influences the postprandial metabolic response in healthy men

      Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., Oct 2015, In: Food & Function. 6, 10, p. 3236-48 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      Important species differences regarding lymph contribution to gut hormone responses

      Hansen, M., Hjøllund, K. R., Hartmann, Bolette, Plamboeck, A., Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 28-31 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1

      Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

      Jensen, E. P., Poulsen, Steen Seier, Kissow, Hannelouise, von Holstein-Rathlou, Niels-Henrik, Deacon, Carolyn F., Jensen, B. L., Holst, Jens Juul & Sorensen, Charlotte Mehlin, 15 Apr 2015, In: A J P: Renal Physiology (Online). 308, 8, p. F867-F877 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide

      Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      Incretin effect after oral amino Acid ingestion in humans

      Lindgren, O., Pacini, G., Tura, A., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 1172-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Stability of glucagon-like peptide-1 and glucagon in human plasma

      Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors

      Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients

      Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      Effects of sitagliptin on blood pressure and heart rate in response to intraduodenal glucose infusion in type 2 diabetes

      Wu, T., Trahair, L., Bound, M., Deacon, Carolyn F., Horowitz, M., Rayner, C. & Jones, K., 2015, In: Diabetic Medicine. 32, 5, p. 595-600 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report

      Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. 2014
    87. Published

      The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

      Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

      Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose

      Vardarli, I., Arndt, E., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Feb 2014, In: Diabetes. 63, 2, p. 663-74 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

      Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      Effects of sitagliptin on glycemia, incretin hormones, and antropyloroduodenal motility in response to intraduodenal glucose infusion in healthy lean and obese humans, and patients with type 2 diabetes treated with or without metformin

      Wu, T., Ma, J., Bound, M., Checklin, H., Deacon, Carolyn F., Jones, K., Horowitz, M. & Raynor, C., 2014, In: Diabetes. 63, 8, p. 2776-2787 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Effects of sitagliptin therapy on markers of low-grade inflammation and cell adhesion molecules in patients with type 2 diabetes

      Tremblay, A., Lamarche, B., Deacon, Carolyn F., Weisnagel, S. & Couture, P., 2014, In: Metabolism. 63, 9, p. 1141-1148 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Effects of the dipeptidyl peptidase IV inhibitor, vildagliptin, on glycemic, gut hormone, triglyceride, energy expenditure and energy intake responses to intraduodenal fat infusion in healthy males

      Heruc, G., Horowitz, M., Deacon, Carolyn F., Feinle-Bisset, C., Rayner, C., Luscombe-Marsh, N. & Little, T. J., 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 307, 9, p. E830-E837 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      No Effect of Aprotinin (Trasylol) on Degradation of Exogenous and Endogenous Glucagon in Human, Mouse and Rat Plasma

      Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Pedersen, Jens, Christensen, M., Vilsboll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Journal of Endocrinology and Diabetes. 1, 1, p. 1-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans

      Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hartmann, Bolette, Christensen, M., Vilsbøll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: European Journal of Endocrinology. 170, 4, p. 529-538 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies

      Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. 2013
    98. Published

      Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety

      Deacon, Carolyn F. & Holst, Jens Juul, Oct 2013, In: Expert Opinion on Pharmacotherapy. 14, 15, p. 2047-58 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

      Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty

      Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    101. Published

      Is there a place for incretin therapies in obesity and prediabetes?

      Holst, Jens Juul & Deacon, Carolyn F., 13 Feb 2013, In: Trends in Endocrinology and Metabolism. 24, 3, p. 145-152 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    102. Published

      The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs

      Simonsen, L., Holst, Jens Juul, Madsen, K. & Deacon, Carolyn F., 10 Feb 2013, In: Regulatory Peptides. 181, 10, p. 17-21 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    103. Published

      Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin

      Holst, Jens Juul, Deacon, Carolyn F., Hartmann, Bolette & Pedersen, Jens, 2013, Handbook of Biologically Active Peptides . Kastin, AJ. (ed.). 2 ed. Elsevier, p. 1241-1250 10 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

    104. Published

      Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?

      van Raalte, D. H., Kwa, K. A. A., van Genugten, R. E., Tushuizen, M. E., Holst, Jens Juul, Deacon, Carolyn F., Karemaker, J. M., Heine, R. J., Mari, A. & Diamant, M., 2013, In: Metabolism. 62, 4, p. 568-577 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    105. 2012
    106. Published

      Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus

      Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. A. & Heise, T., Nov 2012, In: Diabetes Therapy. 3, 1, p. 10

      Research output: Contribution to journal › Journal article › Research › peer-review

    107. Published

      Commentary: Is endogenous GLP-1 the only important enhancer of glucose-induced insulin secretion in type 2 diabetes?

      Deacon, Carolyn F., 2012, In: Diabetes. 61, 9, p. 2219-2220

      Research output: Contribution to journal › Journal article › Research › peer-review

    108. Published

      Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes—a review and meta analysis

      Deacon, Carolyn F., Mannucci, E. & Ahren, B., 2012, In: Diabetes, Obesity and Metabolism Online. 14, 8, p. 762-767

      Research output: Contribution to journal › Review › Research › peer-review

    109. Published

      Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals

      Rohrer, S., Menge, B. A., Grüber, L., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 5, p. E791-E795

      Research output: Contribution to journal › Journal article › Research › peer-review

    110. Published

      Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes.

      Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. & Heise, T., 2012, In: Diabetes Therapy. 3, 1, p. 10

      Research output: Contribution to journal › Journal article › Research › peer-review

    111. Published

      Potential cardiovascular effects of incretin-based therapies

      Deacon, Carolyn F. & Marx, N., 2012, In: Expert Review of Cardiovascular Therapy. 10, p. 337-351

      Research output: Contribution to journal › Review › Research › peer-review

    112. Published

      The effects of sitagliptin on gastric emptying in healthy humans – a randomised controlled study

      Stevens, J., Horowitz, M., Deacon, Carolyn F., Nauck, M., Rayner, C. & Jones, K., 2012, In: Alimentary Pharmacology and Therapeutics. 36, 4, p. 379-390

      Research output: Contribution to journal › Journal article › Research › peer-review

    113. 2011
    114. Published

      Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus

      Stephens, J. W., Bodvarsdottir, T. B., Wareham, K., Prior, S. L., Bracken, R. M., Lowe, G. D., Rumley, A., Dunseath, G., Luzio, S., Deacon, Carolyn F., Holst, Jens Juul & Bain, S. C., Nov 2011, In: Diabetes Research and Clinical Practice. 94, 2, p. 199-206 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    115. Published

      GLP-1 signals via ERK in peripheral nerve and prevents nerve dysfunction in diabetic mice

      Jolivalt, C., Fineman, M., Deacon, Carolyn F., Carr, R. & Calcutt, N., Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 990-1000 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    116. Published

      Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans

      Lindgren, O., Carr, R. D., Deacon, Carolyn F., Holst, Jens Juul, Pacini, G., Mari, A. & Ahrén, B., Aug 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 8, p. 2519-2524 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    117. Published

      Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes

      Menge, B. A., Grüber, L., Jørgensen, S. M., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., Aug 2011, In: Diabetes. 60, 8, p. 2160-2168 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    118. Published

      Dissociated incretin hormone response to protein versus fat ingestion in obese subjects

      Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In: Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    119. Published

      An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future

      Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    120. Published

      Effect of Sitagliptin therapy on postprandial lipoprotein levels in patients with type 2 diabetes

      Tremblay, A., Lamarche, B., Deacon, Carolyn F., Weisnagel, S. & Couture, P., Apr 2011, In: Diabetes, Obesity and Metabolism. 13, 4, p. 366-373 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    121. Published

      Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

      Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, N., Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    122. Published

      Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review

      Deacon, Carolyn F., Jan 2011, In: Diabetes, Obesity and Metabolism. 13, 1, p. 7-18 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    123. Published

      Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones

      Olthof, M., van Dijk, A., Deacon, Carolyn F., Heine, R. & van Dam, R., 2011, In: Nutrition & Metabolism. 8, p. Artikel 10 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    124. Published

      Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs

      Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    125. Published

      Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes

      Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In: Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    126. Published

      GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes

      Mentis, N., Vardarli, I., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Theodorakis, M., Meier, J. J. & Nauck, M. A., 2011, In: Diabetes. 60, 4, p. 1270-1276 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    127. Published

      Incretin-based therapies– review of the physiology, pharmacology and emerging clinical experience

      Martin, J., Deacon, Carolyn F., Gorrell, M. & Prins, J., 2011, In: Internal Medicine Journal (Online). 41, p. 299-307 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    128. Published

      Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes

      Vardarli, I., Nauck, M. A., Köthe, L. D., Deacon, Carolyn F., Holst, Jens Juul, Schweizer, A. & Foley, J. E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 4, p. 945-954 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    129. Published

      Physiology of incretins in health and disease

      Deacon, Carolyn F. & Ahren, B., 2011, In: Review of Diabetic Studies. 8, 3, p. 293-306 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    130. Published

      Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?

      Nauck, M. A., Vardarli, I., Deacon, Carolyn F., Holst, Jens Juul & Meier, J., 2011, In: Diabetologia. 54, 1, p. 10-18 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    131. 2010
    132. Published

      Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

      Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    133. Published

      Impact of exogenous hyperglucagonemia on postprandial concentrations of gastric inhibitory polypeptide and glucagon-like peptide-1 in humans

      Meier, J. J., Ritter, P. R., Jacob, A., Menge, B. A., Deacon, Carolyn F., Schmidt, W. E., Nauck, M. A. & Holst, Jens Juul, 1 Aug 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 4061-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    134. Published

      The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

      Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    135. Published

      Little enhancement of meal-induced glucagon-like peptide 1 secretion in Japanese: Comparison of type 2 diabetes patients and healthy controls

      Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., 22 Apr 2010, In: Journal of Diabetes Investigation. 1, 1-2, p. 56-9 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    136. Published

      Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus

      Aaboe, K., Knop, Filip Krag, Vilsbøll, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S. & Krarup, T. M., 1 Apr 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-33 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    137. Published

      Reversible hyperinsulinemic hypoglycemia after gastric bypass: a consequence of altered nutrient delivery

      McLaughlin, T., Peck, M., Holst, Jens Juul & Deacon, Carolyn F., Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1851-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    138. Published

      Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

      Deacon, Carolyn F. & Holst, Jens Juul, Jan 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-40 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    139. Published

      Little enhancement of meal-induced GLP-1 secretion in Japanese: Comparison of type 2 diabetes and healthy controls

      Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., Jan 2010, In: Journal of Diabetes Investigation. 1, 1/2, p. 56-59

      Research output: Contribution to journal › Journal article › Research › peer-review

    140. Published

      Incretin hormone secretion over the day

      Ahren, B., Carr, R. & Deacon, Carolyn F., 2010, In: Vitamins and Hormones. 84, p. 203-220 18 p.

      Research output: Contribution to journal › Review › Research › peer-review

    141. Published

      Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

      Deacon, Carolyn F. & Holst, Jens Juul, 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-140 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    142. Published

      Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

      Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    143. Published

      Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

      Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    144. Published

      Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men

      Carr, R. D., Larsen, M. O., Jelic, K., Lindgren, O., Vikman, J., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 872-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    145. Published

      The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose

      Bock, G., Man, C. D., Micheletto, F., Basu, R., Rn, P. D. G., Laugen, J., Deacon, Carolyn F., Holst, Jens Juul, Toffolo, G., Cobelli, C., Rizza, R. A. & Vella, A., 2010, In: Clinical Endocrinology. 73, p. 189-196

      Research output: Contribution to journal › Journal article › Research › peer-review

    146. Published

      Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus

      Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    147. 2009
    148. Published

      DPP-4 inhibition – advances in our understanding of diabetes management

      Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: European Endocrinology. 4, p. 47-49

      Research output: Contribution to journal › Review › Research

    149. Published

      Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men

      Lindgren, O., Mari, A., Deacon, Carolyn F., Carr, R. D., Winzell, M. S., Vikman, J. & Ahrén, B., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 2887-92 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    150. Published

      Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans

      Vollmer, K., Gardiwal, H., Menge, B. A., Goetze, O., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Meier, J. J., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1379-85 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    151. Published

      Immunoassays for the incretin hormones GIP and GLP-1

      Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 425-32 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    152. Published

      Incretin hormones and diabetes mellitus

      Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F. & Holst, Jens Juul, 2009, Therapeutic Strategies in Diabetes. Stehouwer, C. D. A. & Schaper, N. (eds.). Oxford: Clinical Publishing, p. 99-114

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    153. Published

      Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats

      Simonsen, L., Pilgaard, S., Carr, R. D., Kanstrup, A. B., Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Hormone and Metabolic Research. 41, 11, p. 851-3 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    154. Published

      KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes

      Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608

      Research output: Contribution to journal › Journal article › Research › peer-review

    155. Published

      Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats

      Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    156. Published

      Potential of liraglutide in the treatment of patients with type 2 diabetes

      Deacon, Carolyn F., 2009, In: Vascular Health and Risk Management (Online). 5, 1, p. 199-211 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    157. Published

      Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

      Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    158. Published

      Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes

      Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: Advances in Therapy. 26, 5, p. 488-99 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    159. Published

      Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial

      Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748

      Research output: Contribution to journal › Conference abstract in journal › Research

    160. 2008
    161. Published

      Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes

      Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In: Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    162. Published

      Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

      Madsbad, Sten, Krarup, T., Deacon, Carolyn F. & Holst, Jens Juul, Jul 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    163. Published

      Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes.

      Deacon, Carolyn F., 2008, In: Current Opinion in Investigational Drugs. 9, 4, p. 402-13 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    164. Published

      DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes

      Deacon, Carolyn F., Carr, R. D. & Holst, Jens Juul, 2008, In: Frontiers in Bioscience. 13, p. 1780-94 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    165. Published

      Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes

      Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In: Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    166. Published

      Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance.

      Rosenstock, J., Foley, J. E., Rendell, M., Landin-Olsson, M., Holst, Jens Juul, Deacon, Carolyn F., Rochotte, E. & Baron, M. A., 2008, In: Diabetes Care. 31, 1, p. 30-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    167. Published

      Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

      Madsbad, Sten, Krarup, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Deacon, C. F. & Holst, J. J., 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    168. Published

      Glucagon-like peptide-1, glucose homeostasis and diabetes.

      Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In: Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    169. Published

      Incretin and islet hormonal responses to fat and protein ingestion in healthy men.

      Carr, R. D., Larsen, M. O., Winzell, M. S., Jelic, K., Lindgren, O., Deacon, Carolyn F. & Ahrén, B., 2008, In: American Journal of Physiology: Endocrinology and Metabolism. 295, 4, p. E779-84

      Research output: Contribution to journal › Journal article › Research › peer-review

    170. Published

      KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

      Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    171. Published

      Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus.

      Azuma, K., Radikova, Z., Mancino, J., Toledo, F., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D. & Kelley, D., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, p. 459-463

      Research output: Contribution to journal › Journal article › Research › peer-review

    172. Published

      Overnight hypoxic exposure and glucagon-like peptide-1 and leptin levels in humans.

      Snyder, E. M., Carr, R. D., Deacon, Carolyn F. & Johnson, B. D., 2008, In: Applied Physiology, Nutrition and Metabolism. 33, 5, p. 929-35 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    173. Published

      The effect of dipeptidyl peptidase 4 inhibition on gastric volume, satiation and enteroendocrine secretion in Type 2 diabetes: a double blind, placebo-controlled crossover study.

      Vella, A., Bock, G., Giesler, P. D., Burton, D. B., Serra, D. B., Saylan, M. L., Deacon, Carolyn F., Foley, J. E., Rizza, R. A. & Camilleri, M., 2008, In: Clinical Endocrinology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    174. Published

      The incretin system and its role in type 2 diabetes mellitus

      Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In: Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    175. 2007
    176. Published

      Dipeptidyl peptidase 4 inhibition with sitagliptin: a new therapy for type 2 diabetes.

      Deacon, Carolyn F., 2007, In: Expert Opinion on Investigational Drugs. 16, 4, p. 533-45 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    177. Published

      Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.

      Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95

      Research output: Contribution to journal › Journal article › Research › peer-review

    178. Published

      Incretin-based treatment of type 2 diabetes: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors.

      Deacon, Carolyn F., 2007, In: Diabetes, Obesity and Metabolism. 9 Suppl 1, p. 23-31 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    179. Published

      Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes

      Azuma, K., Rádiková, Z., Mancino, J., Toledo, F. G. S., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D., Foley, J. E. & Kelley, D. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 459-464 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    180. Published

      New horizons in diabetes therapy

      Holst, Jens Juul & Deacon, Carolyn F., 2007, In: Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7, 1, p. 49-55 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    181. Published

      Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.

      He, Y., Wang, Y., Bullock, J. M., Deacon, Carolyn F., Holst, Jens Juul, Dunning, B. E., Ligueros-Saylan, M. & Foley, J. E., 2007, In: Journal of Clinical Pharmacology. 47, 5, p. 633-41 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    182. Published

      Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.

      He, Y., Serra, D., Wang, Y., Campestrini, J., Riviere, G., Deacon, Carolyn F., Holst, Jens Juul, Schwartz, S., Nielsen, J. C. & Ligueros-Saylan, M., 2007, In: Clinical Pharmacokinetics. 46, 7, p. 577-88 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    183. Published

      Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects

      Meier, J. J., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Nauck, M. A., 2007, In: Diabetologia. 50, 4, p. 806-813 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    184. Published

      The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients.

      Balas, B., Baig, M. R., Watson, C., Dunning, B. E., Ligueros-Saylan, M., Wang, Y., He, Y., Darland, C., Holst, Jens Juul, Deacon, Carolyn F., Cusi, K., Mari, A., Foley, J. E. & DeFronzo, R. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 4, p. 1249-55 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    185. Published

      The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose

      Utzschneider, K. M., Tong, J., Montgomery, B., Udayasankar, J., Gerchman, F., Marcovina, S. M., Watson, C. E., Ligueros-Saylan, M. A., Foley, J. E., Holst, Jens Juul, Deacon, Carolyn F. & Kahn, S. E., 2007, In: Diabetes Care. 31, 1, p. 108-113 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    186. 2006
    187. Published

      Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake

      Ryskjaer, J., Deacon, Carolyn F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Vilsbøll, Tina, Ryskjaer, J., Deacon, C. F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, J. J. & Vilsbøll, T., 1 Sep 2006, In: European Journal of Endocrinology. 155, 3, p. 485-93 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    188. Published

      Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

      Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., Apr 2006, In: Diabetologia. 49, 4, p. 706-12 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    189. Published

      The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

      Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    190. Published

      Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.

      Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q. & 7 others, Zeng, W., Davies, M. J., Tanaka, W., Holst, Jens Juul, Deacon, Carolyn F., Gottesdiener, K. M. & Wagner, J. A., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    191. Published

      Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

      Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Diabetologia. 49, 4, p. 706-712 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    192. Published

      GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations.

      Deacon, Carolyn F., Plamboeck, A., Rosenkilde, Mette, de Heer, J. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 3, p. E468-75

      Research output: Contribution to journal › Journal article › Research › peer-review

    193. Published

      Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice.

      Gunnarsson, P. T., Winzell, M. S., Deacon, Carolyn F., Larsen, M. O., Jelic, K., Carr, R. D. & Ahrén, B., 2006, In: Endocrinology. 147, 7, p. 3173-80 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    194. Published

      Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagons, lactate and TNF-alfa in patients with HIV-lipodystrophy

      Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J. & Madsbad, Sten, 2006, In: HIV Medicine. 7, p. 163-172 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    195. Published

      Influence of gastric inhibitory polypeptide on pentagastrin-stimulated gastric acid secretion in patients with type 2 diabetes and healthy controls.

      Meier, J. J., Nauck, M. A., Kask, B., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2006, In: World Journal of Gastroenterology. 12, 12, p. 1874-80 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    196. Published

      Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.

      Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, Randi Kjærsgaard, Plamboeck, A. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 138, 2-3, p. 126-32 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    197. Published

      Role of GLP-1 analogues and DDP-IV inhibitors in the treatment of type 2 diabetes

      Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Avances en Diabetologia. 22, 2, p. 115-125 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    198. Published

      The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.

      Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    199. Published

      The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.

      Meier, J. J., Gethmann, A., Nauck, M. A., Götze, O., Schmitz, F., Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 6, p. E1118-23

      Research output: Contribution to journal › Journal article › Research › peer-review

    200. Published

      The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

      Zander, M., Madsbad, S., Deacon, Carolyn F. & Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 369-374 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    201. 2005
    202. Published

      Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig

      Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., Sep 2005, In: Diabetologia. 48, 9, p. 1882-90 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    203. Published

      Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes

      Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2005, In: Diabetologia. 48, 9, p. 1872-81 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    204. Published

      Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes

      Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., Aug 2005, In: The Journal of clinical endocrinology and metabolism. 90, 8, p. 4888-94 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    205. Published

      Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors

      Holst, Jens Juul & Deacon, Carolyn F., Apr 2005, In: Diabetologia. 48, 4, p. 612-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    206. Published

      Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy

      Andersen, Ove, Haugaard, Steen Bendix, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, Sten, Mar 2005, In: HIV Medicine. 6, 2, p. 91-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    207. Published

      Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes.

      Deacon, Carolyn F. & Holst, Jens Juul, 2005, In: International Journal of Biochemistry & Cell Biology. 38, 5-6, p. 831-44 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    208. Published

      Enhanced glucagon-like peptide- 1 (GLP-1) response to oral glucose in glucose intolerant HIV-infected patients on antiretroviral therapy

      Andersen, O., Haugaard, S. B., Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, S., 2005, In: HIV Medicine. 6, p. 91-98

      Research output: Contribution to journal › Journal article › Research › peer-review

    209. Published

      For debate: Are antidiabetic actions of DPP-IV inhibitors mediated by glucagon-like peptide- 1?

      Holst, Jens Juul & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 612-615

      Research output: Contribution to journal › Journal article › Research › peer-review

    210. Published

      Glucagon-like peptide-1 mediates the therapeutic actions of Dpp-IV inhibitors

      Holst, Jens Juul & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 612-615

      Research output: Contribution to journal › Journal article › Research › peer-review

    211. Published

      Insulinotropic effect of gastric inhibitory polypeptide (GIP) in women with a history of gestational diabetes

      Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2005, In: Diabetologia. 48, p. 1872-1881

      Research output: Contribution to journal › Journal article › Research

    212. Published

      MK-431 (Merck).

      Deacon, Carolyn F., 2005, In: Current Opinion in Investigational Drugs. 6, 4, p. 419-26 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    213. Published

      Neutral Endopeptidase 24.11 and dipeptidyl peptidase IV are both physiological mediators of the degradation of glucagon-like peptide-1 in the anaesthetized pig

      Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 1882-1890

      Research output: Contribution to journal › Journal article › Research › peer-review

    214. Published

      Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight

      Schou, J. H., Pilgaard, K., Vilsbøll, Tina, Jensen, C. B., Deacon, Carolyn F., Holst, Jens Juul, Vølund, A., Madsbad, Sten & Vaag, Allan, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 8, p. 4912-19 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    215. Published

      Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV.

      Gram, D. X., Hansen, A. J., Deacon, Carolyn F., Brand, C. L., Ribel, U., Wilken, M., Carr, R. D., Svendsen, O. & Ahrén, B., 2005, In: European Journal of Pharmacology. 509, 2-3, p. 211-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    216. Published

      The incretin enhancer vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed -cell function in patients with type 2 diabetes

      Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, p. 4888-4894

      Research output: Contribution to journal › Journal article › Research

    217. Published

      Vildagliptin, a dipeptidyl peptidase-IV inhibitor improves model-assessed beta-cell function in patients with type 2 diabetes

      Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Duning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 4888-4894

      Research output: Contribution to journal › Journal article › Research

    218. Published

      What do we know about the secretion and degradation of incretin hormones?

      Deacon, Carolyn F., 2005, In: Regulatory Peptides. 128, 2, p. 117-24 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    219. 2004
    220. Published

      Circulation and degradation of GIP and GLP-1

      Deacon, Carolyn F., 2004, In: Hormone and Metabolic Research. 36, p. 761-765

      Research output: Contribution to journal › Journal article › Research › peer-review

    221. Published

      Glucagon-like peptide 1 and inhibitors of dipeptidyl peptidase IV in the treatment of type 2 diabetes mellitus.

      Holst, Jens Juul & Deacon, Carolyn F., 2004, In: Current Opinion in Pharmacology. 4, 6, p. 589-96 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    222. Published

      Inhibitors of dipeptidyl peptidase IV: a novel approach for the prevention and treatment of Type 2 diabetes?

      Deacon, Carolyn F., Ahrén, B. & Holst, Jens Juul, 2004, In: Expert Opinion on Investigational Drugs. 13, 9, p. 1091-102 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    223. Published

      Neutral endopeptidase 24.11 is important for the degradation of both endogenous and exogenous glucagon in anesthetized pigs.

      Trebbien, R., Klarskov, L., Olesen, M., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 3, p. E431-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    224. Published

      Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.

      Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In: Regulatory Peptides. 122, 3, p. 209-17 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    225. Published

      Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.

      Meier, J. J., Nauck, M. A., Kranz, D., Holst, Jens Juul, Deacon, Carolyn F., Gaeckler, D., Schmidt, W. E. & Gallwitz, B., 2004, In: Diabetes. 53, 3, p. 654-62 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    226. Published

      Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.

      Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In: Diabetes. 53 Suppl 3, p. S220-4

      Research output: Contribution to journal › Journal article › Research › peer-review

    227. Published

      The major glucagon-like peptide-1 metabolite, GLP-1-(9-36)-amide, does not affect glucose or insulin levels in mice.

      Rolin, B., Deacon, Carolyn F., Carr, R. D. & Ahrén, B., 2004, In: European Journal of Pharmacology. 494, 2-3, p. 283-8 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    228. Published

      Therapeutic strategies based on glucagon-like peptide 1.

      Deacon, Carolyn F., 2004, In: Diabetes. 53, 9, p. 2181-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    229. 2003
    230. Published

      Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

      Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., Jun 2003, In: Diabetologia. 46, 6, p. 798-801 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    231. Published

      Differential regional metabolism of glucagon in anesthetized pigs.

      Deacon, Carolyn F., Kelstrup, M., Trebbien, R., Klarskov, L., Olesen, M. & Holst, Jens Juul, 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 285, 3, p. E552-60

      Research output: Contribution to journal › Journal article › Research › peer-review

    232. Published

      GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics.

      Sturis, J., Gotfredsen, C. F., Rømer, J., Rolin, B., Ribel, U., Brand, C. L., Wilken, M., Wassermann, K., Deacon, Carolyn F., Carr, R. D. & Knudsen, L. B., 2003, In: British Journal of Pharmacology. 140, 1, p. 123-32 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    233. Published

      Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

      Meier, J. J., Gallwitz, N., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Diabetologia. 46, p. 798-801

      Research output: Contribution to journal › Journal article › Research › peer-review

    234. Published

      Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.

      Ugleholdt, Randi Kjærsgaard, Zhu, X., Deacon, Carolyn F., Ørskov, Cathrine, Steiner, D. F. & Holst, Jens Juul, 2003, In: Endocrinology. 145, 3, p. 1349-55 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    235. Published

      Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.

      Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2003, In: Advances in Experimental Medicine and Biology. 524, p. 303-12 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    236. Published

      Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.

      Meier, J. J., Nauck, M. A., Siepmann, N., Greulich, M., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2003, In: Metabolism - Clinical and Experimental. 52, 12, p. 1579-85 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    237. Published

      The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP).

      Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Regulatory Peptides. 113, 1-3, p. 95-100 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    238. Published

      Valine pyrrolidide preserves intact glucose-dependent insulinotropic peptide and improves abnormal glucose tolerance in minipigs with reduced beta-cell mass.

      Larsen, M. O., Rolin, B., Ribel, U., Wilken, M., Deacon, Carolyn F., Svendsen, O., Gotfredsen, C. F. & Carr, R. D., 2003, In: Experimental Diabesity Research. 4, 2, p. 93-105 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    239. 2002
    240. Published

      Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs

      Deacon, Carolyn F., Wamberg, S., Bie, P., Hughes, T. E. & Holst, Jens Juul, Feb 2002, In: Journal of Endocrinology. 172, 2, p. 355-62 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    241. Published

      Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective.

      Deacon, Carolyn F. & Holst, Jens Juul, 2002, In: Biochemical and Biophysical Research Communications. 294, 1, p. 1-4 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    242. Published

      GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion.

      Deacon, Carolyn F., Plamboeck, A., Møller, Søren & Holst, Jens Juul, 2002, In: American Journal of Physiology: Endocrinology and Metabolism. 282, 4, p. E873-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    243. Published

      NN2211: a long-acting glucagon-like peptide-1 derivative with anti-diabetic effects in glucose-intolerant pigs.

      Ribel, U., Larsen, M. O., Rolin, B., Carr, R. D., Wilken, M., Sturis, J., Westergaard, L., Deacon, Carolyn F. & Knudsen, L. B., 2002, In: European Journal of Pharmacology. 451, 2, p. 217-25 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    244. Published

      The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice.

      Rolin, B., Larsen, M. O., Gotfredsen, C. F., Deacon, Carolyn F., Carr, R. D., Wilken, M. & Knudsen, L. B., 2002, In: American Journal of Physiology: Endocrinology and Metabolism. 283, 4, p. E745-52

      Research output: Contribution to journal › Journal article › Research › peer-review

    245. 2001
    246. Published

      Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs

      Deacon, Carolyn F., Danielsen, P., Klarskov, L., Holst, Jens Juul & Olesen, M., 2001, In: Diabetes. 50, p. 1588-1597

      Research output: Contribution to journal › Journal article › Research › peer-review

    247. Published

      Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes

      Meier, J. J., Huking, K., Holst, Jens Juul, Deacon, Carolyn F., Schmiegel, W. H. & Nauck, M. A., 2001, In: Diabetes. 50, p. 2497-2504

      Research output: Contribution to journal › Journal article › Research › peer-review

    248. 2000
    249. Published

      Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide

      Deacon, Carolyn F., Nauck, M. A., Meier, J., Hücking, K. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 3575-3581

      Research output: Contribution to journal › Journal article › Research › peer-review

    250. Published

      In vivo and in vitro degradation of glucagon-like peptide-2 in humans

      Hartmann, B., Harr, M. B., Jeppesen, P. B., Wojdemann, M., Deacon, Carolyn F., Mortensen, P. B. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 2884-2888

      Research output: Contribution to journal › Journal article › Research › peer-review

    251. 1999
    252. Published

      Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine

      Hansen, L., Deacon, Carolyn F., Ørskov, Cathrine & Holst, Jens Juul, Nov 1999, In: Molecular Endocrinology. 140, 11, p. 5356-63 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    253. Published

      Glucagon-like peptide-1: a basis for new approaches to the management of diabetes

      Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., Mar 1999, In: Drugs of Today. 35, 3, p. 159-70 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    254. Published

      Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells

      Hansen, L., Deacon, Carolyn F., Ørskov, C. & Holst, Jens Juul, 1999, In: Endokrinologiya. 140, p. 5356-5363

      Research output: Contribution to journal › Journal article › Research › peer-review

    255. Published

      Glucagon-like peptide-1: A basis for new approaches to the management of Diabetes

      Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., 1999, In: Drugs of Today. 35, p. 159-170

      Research output: Contribution to journal › Journal article › Research › peer-review

    256. 1998
    257. Published

      Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

      Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769

      Research output: Contribution to journal › Journal article › Research › peer-review

    258. Published

      Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

      Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278

      Research output: Contribution to journal › Journal article › Research › peer-review

    259. Published

      Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

      Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670

      Research output: Contribution to journal › Journal article › Research › peer-review

    260. Published

      On the treatment of diabetes mellitus with glucagon-like peptide-1.

      Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343

      Research output: Contribution to journal › Journal article › Research › peer-review

    261. 1997
    262. Published

      Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

      Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    263. 1996
    264. Published

      Plasma TNF-x is associated with insulin mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy

      Haugaard, S. B., Andersen, O., Pedersen, S. B., Dela, Flemming & Deacon, Carolyn F., 1996, In: Metabolism - Clinical and Experimental. 55(2), p. 175-182

      Research output: Contribution to journal › Journal article › Research › peer-review

    265. 1995
    266. Published

      Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

      Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131

      Research output: Contribution to journal › Journal article › Research › peer-review

    267. Published

      Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.

      Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957

      Research output: Contribution to journal › Journal article › Research › peer-review

    268. Published

      Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).

      Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.

      Research output: Contribution to journal › Journal article › Research › peer-review

    ID: 9220