Carolyn F. Deacon
Carolyn F. Deacon

Associate Professor


  1. Published

    Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Larsen, O., Jepsen, Sara Lind, Balk-Møller, E., Andersen, Daniel Bjørklund, Deacon, Carolyn F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, Reidar, Hartmann, Bolette, Rosenkilde, Mette & Holst, Jens Juul, 2018, In : Molecular Metabolism. 11, p. 84-95 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Peptide production and secretion in GLUTag, NCI-H716 and STC-1 cells: a comparison to native L-cells.

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Balk-Møller, E., Rehfeld, Jens Frederik, Relman, F., Gribble, F. M. & Holst, Jens Juul, 2016, In : Journal of Molecular Endocrinology. 56, p. 201-211

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    GLP-1 signals via ERK in peripheral nerve and prevents nerve dysfunction in diabetic mice

    Jolivalt, C., Fineman, M., Deacon, Carolyn F., Carr, R. & Calcutt, N., Nov 2011, In : Diabetes, Obesity and Metabolism. 13, 11, p. 990-1000 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice

    Jepsen, Sara Lind, Grunddal, Kaare Villum, Albrechtsen, Nicolai Jacob Wewer, Engelstoft, M. S., Gabe, Maria Buur Nordskov, Jensen, E. P., Ørskov, Cathrine, Poulsen, Steen Seier, Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, Carolyn F., Schwartz, Thue W., Christ, A. D., Martin, R. E. & Holst, Jens Juul, 2019, In : American Journal of Physiology: Endocrinology and Metabolism. 317, 6, p. E1081-E1093

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

    Jensen, E. P., Poulsen, Steen Seier, Kissow, Hannelouise, Holstein-Rathlou, N., Deacon, Carolyn F., Jensen, B. L., Holst, Jens Juul & Sorensen, Charlotte Mehlin, 15 Apr 2015, In : A J P: Renal Physiology (Online). 308, 8, p. F867-F877 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Glucagon-like peptide 1 and inhibitors of dipeptidyl peptidase IV in the treatment of type 2 diabetes mellitus.

    Holst, Jens Juul & Deacon, Carolyn F., 2004, In : Current Opinion in Pharmacology. 4, 6, p. 589-96 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Glucagon-like peptide-1, glucose homeostasis and diabetes.

    Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In : Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Glucagon-like peptide-1 mediates the therapeutic actions of Dpp-IV inhibitors

    Holst, Jens Juul & Deacon, Carolyn F., 2005, In : Diabetologia. 48, p. 612-615

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The incretin system and its role in type 2 diabetes mellitus

    Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In : Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    For debate: Are antidiabetic actions of DPP-IV inhibitors mediated by glucagon-like peptide- 1?

    Holst, Jens Juul & Deacon, Carolyn F., 2005, In : Diabetologia. 48, p. 612-615

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors

    Holst, Jens Juul & Deacon, Carolyn F., Apr 2005, In : Diabetologia. 48, 4, p. 612-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

    Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  13. Published

    Is there a place for incretin therapies in obesity and prediabetes?

    Holst, Jens Juul & Deacon, Carolyn F., 13 Feb 2013, In : Trends in Endocrinology and Metabolism. 24, 3, p. 145-152 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin

    Holst, Jens Juul, Deacon, Carolyn F., Hartmann, Bolette & Pedersen, J., 2013, Handbook of Biologically Active Peptides . Kastin, AJ. (ed.). 2 ed. Elsevier, p. 1241-1250 10 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  15. Published

    Physiology of the Incretin Hormones, GIP and GLP-1-Regulation of Release and Posttranslational Modifications

    Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Rosenkilde, Mette & Deacon, Carolyn F., 2019, In : Comprehensive Physiology. 9, 4, p. 1339-1381

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1.

    Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In : Annals of the New York Academy of Sciences. 865, p. 336-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 1998, In : Diabetes. 47, p. 1663-1670

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Role of GLP-1 analogues and DDP-IV inhibitors in the treatment of type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 2006, In : Avances en Diabetologia. 22, 2, p. 115-125 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    New horizons in diabetes therapy

    Holst, Jens Juul & Deacon, Carolyn F., 2007, In : Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7, 1, p. 49-55 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs

    Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In : Diabetologia. 54, 8, p. 2206-8 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  21. Published

    Effects of the dipeptidyl peptidase IV inhibitor, vildagliptin, on glycemic, gut hormone, triglyceride, energy expenditure and energy intake responses to intraduodenal fat infusion in healthy males

    Heruc, G., Horowitz, M., Deacon, Carolyn F., Feinle-Bisset, C., Rayner, C., Luscombe-Marsh, N. & Little, T. J., 2014, In : American Journal of Physiology: Endocrinology and Metabolism. 307, 9, p. E830-E837 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.

    Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q., Zeng, W., Davies, M. J., Tanaka, W., Holst, Jens Juul, Deacon, Carolyn F., Gottesdiener, K. M. & Wagner, J. A., 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes

    Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In : Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.

    He, Y., Wang, Y., Bullock, J. M., Deacon, Carolyn F., Holst, Jens Juul, Dunning, B. E., Ligueros-Saylan, M. & Foley, J. E., 2007, In : Journal of Clinical Pharmacology. 47, 5, p. 633-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.

    He, Y., Serra, D., Wang, Y., Campestrini, J., Riviere, G., Deacon, Carolyn F., Holst, Jens Juul, Schwartz, S., Nielsen, J. C. & Ligueros-Saylan, M., 2007, In : Clinical Pharmacokinetics. 46, 7, p. 577-88 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Plasma TNF-x is associated with insulin mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy

    Haugaard, S. B., Andersen, O., Pedersen, S. B., Dela, Flemming & Deacon, Carolyn F., 1996, In : Metabolism - Clinical and Experimental. 55(2), p. 175-182

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy

    Haugaard, S. B., Andersen, O., Pedersen, S. B., Dela, Flemming, Deacon, Carolyn F., Holst, Jens Juul, Iversen, J. & Madsbad, Sten, 2006, In : HIV Medicine. 7, 3, p. 163-72 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    In vivo and in vitro degradation of glucagon-like peptide-2 in humans

    Hartmann, B., Harr, M. B., Jeppesen, P. B., Wojdemann, M., Deacon, Carolyn F., Mortensen, P. B. & Holst, Jens Juul, 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, p. 2884-2888

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

    Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

    Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In : Diabetes. 59, 7, p. 1765-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Important species differences regarding lymph contribution to gut hormone responses

    Hansen, Marie, Hjøllund, K. R., Hartmann, Bolette, Plamboeck, A., Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, Sep 2015, In : Peptides. 71, p. 28-31 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.

    Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, R. K., Plamboeck, A. & Holst, Jens Juul, 2006, In : Regulatory Peptides. 138, 2-3, p. 126-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells

    Hansen, L., Deacon, Carolyn F., Ørskov, C. & Holst, Jens Juul, 1999, In : Endokrinologiya. 140, p. 5356-5363

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine

    Hansen, L., Deacon, Carolyn F., Ørskov, Cathrine & Holst, Jens Juul, Nov 1999, In : Molecular Endocrinology. 140, 11, p. 5356-63 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice.

    Gunnarsson, P. T., Winzell, M. S., Deacon, Carolyn F., Larsen, M. O., Jelic, K., Carr, R. D. & Ahrén, B., 2006, In : Endocrinology. 147, 7, p. 3173-80 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV.

    Gram, D. X., Hansen, A. J., Deacon, Carolyn F., Brand, C. L., Ribel, U., Wilken, M., Carr, R. D., Svendsen, O. & Ahrén, B., 2005, In : European Journal of Pharmacology. 509, 2-3, p. 211-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published
  38. Published

    Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes

    Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In : Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes

    Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In : Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men

    Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In : European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The structure of wheat bread influences the postprandial metabolic response in healthy men

    Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., Oct 2015, In : Food & Function. 6, 10, p. 3236-48 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review

    Deacon, Carolyn F., Jan 2011, In : Diabetes, Obesity and Metabolism. 13, 1, p. 7-18 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Potential cardiovascular effects of incretin-based therapies

    Deacon, Carolyn F. & Marx, N., 2012, In : Expert Review of Cardiovascular Therapy. 10, p. 337-351

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas.

    Deacon, Carolyn F. & Lebovitz, H., 2016, In : Diabetes, Obesity and Metabolism. 18, 4, p. 333-347 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    A comparative review of DPP-4 inhibitors and sulphonylureas

    Deacon, Carolyn F. & Lebovitz, H., 2016, In : Diabetes, Obesity and Metabolism. 18, p. 333-347

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Circulation and degradation of GIP and GLP-1

    Deacon, Carolyn F., 2004, In : Hormone and Metabolic Research. 36, p. 761-765

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes—a review and meta analysis

    Deacon, Carolyn F., Mannucci, E. & Ahren, B., 2012, In : Diabetes, Obesity and Metabolism Online. 14, 8, p. 762-767

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

    Deacon, Carolyn F. & Holst, Jens Juul, 2010, In : Expert Opinion on Investigational Drugs. 19, 1, p. 133-140 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    DPP-4 inhibitors

    Deacon, Carolyn F., 2016, Handbook of incretin therapies in type 2 diabetes. Gough, S. (ed.). Switzerland: Springer, p. 45-60

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  50. Published

    A review of dipeptidyl peptidase-4 inhibitors. Hot topics from randomised controlled trials

    Deacon, Carolyn F., 2018, In : Diabetes, Obesity and Metabolism. 20, Suppl. 1, p. 34-46

    Research output: Contribution to journalReviewResearchpeer-review

ID: 9220