Carolyn F. Deacon
Associate Professor
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Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition: a randomized, prospective comparison of sitagliptin and vildagliptin treatment
Baranov, O., Kahle, M., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Nov 2016, In: Diabetes, Obesity and Metabolism. 18, 11, p. 1100-1109 10 p.Research output: Contribution to journal › Journal article › peer-review
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The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose
Bock, G., Man, C. D., Micheletto, F., Basu, R., Rn, P. D. G., Laugen, J., Deacon, Carolyn F., Holst, Jens Juul, Toffolo, G., Cobelli, C., Rizza, R. A. & Vella, A., 2010, In: Clinical Endocrinology. 73, p. 189-196Research output: Contribution to journal › Journal article › peer-review
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Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men
Carr, R. D., Larsen, M. O., Jelic, K., Lindgren, O., Vikman, J., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 872-8 6 p.Research output: Contribution to journal › Journal article › peer-review
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Incretin and islet hormonal responses to fat and protein ingestion in healthy men.
Carr, R. D., Larsen, M. O., Winzell, M. S., Jelic, K., Lindgren, O., Deacon, Carolyn F. & Ahrén, B., 2008, In: American Journal of Physiology: Endocrinology and Metabolism. 295, 4, p. E779-84Research output: Contribution to journal › Journal article › peer-review
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Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice
Christiansen, Charlotte Bayer, Jepsen, Sara Lind, Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, Rune Ehrenreich, Hartmann, Bolette, Mandrup-Poulsen, Thomas, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.Research output: Contribution to journal › Journal article › peer-review
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Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study
Clarke, S. J., Pettit, S., Giblett, J. P., Zhao, T., Kydd, A. C., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Parameshwar, J. & Hoole, S. P., 2019, In: Clinical Therapeutics. 41, 1, p. 118-127 10 p.Research output: Contribution to journal › Journal article › peer-review
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GLP-1 Is a Coronary Artery Vasodilator in Humans
Clarke, S. J., Giblett, J. P., Yang, L. L., Hubsch, A., Zhao, T., Aetesam-ur-Rahman, M., West, N. E. J., O'Sullivan, M., Figg, N., Bennett, M., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Cheriyan, J. & Hoole, S. P., 20 Nov 2018, In: Journal of the American Heart Association. 7, 22, 14 p., e010321.Research output: Contribution to journal › Journal article › peer-review
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The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report
Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.Research output: Contribution to journal › Journal article › peer-review
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Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia
Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540Research output: Contribution to journal › Journal article › peer-review
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Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs
Deacon, Carolyn F., Wamberg, S., Bie, P., Hughes, T. E. & Holst, Jens Juul, Feb 2002, In: Journal of Endocrinology. 172, 2, p. 355-62 8 p.Research output: Contribution to journal › Journal article › peer-review
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Glucagon-like peptide-1: a basis for new approaches to the management of diabetes
Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., Mar 1999, In: Drugs of Today. 35, 3, p. 159-70 12 p.Research output: Contribution to journal › Journal article › peer-review
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Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide
Deacon, Carolyn F., Nauck, M. A., Meier, J., Hücking, K. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 3575-3581Research output: Contribution to journal › Journal article › peer-review
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Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).
Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.Research output: Contribution to journal › Journal article › peer-review
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Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.
Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity
Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278Research output: Contribution to journal › Journal article › peer-review
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Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.
Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs
Deacon, Carolyn F., Danielsen, P., Klarskov, L., Holst, Jens Juul & Olesen, M., 2001, In: Diabetes. 50, p. 1588-1597Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.
Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769Research output: Contribution to journal › Journal article › peer-review
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Glucagon-like peptide-1: A basis for new approaches to the management of Diabetes
Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., 1999, In: Drugs of Today. 35, p. 159-170Research output: Contribution to journal › Journal article › peer-review
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What do we know about the secretion and degradation of incretin hormones?
Deacon, Carolyn F., 2005, In: Regulatory Peptides. 128, 2, p. 117-24 7 p.Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective.
Deacon, Carolyn F. & Holst, Jens Juul, 2002, In: Biochemical and Biophysical Research Communications. 294, 1, p. 1-4 3 p.Research output: Contribution to journal › Journal article › peer-review
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Immunoassays for the incretin hormones GIP and GLP-1
Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 425-32 7 p.Research output: Contribution to journal › Journal article › peer-review
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MK-431 (Merck).
Deacon, Carolyn F., 2005, In: Current Opinion in Investigational Drugs. 6, 4, p. 419-26 7 p.Research output: Contribution to journal › Journal article › peer-review
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Dipeptidyl peptidase 4 inhibition with sitagliptin: a new therapy for type 2 diabetes.
Deacon, Carolyn F., 2007, In: Expert Opinion on Investigational Drugs. 16, 4, p. 533-45 12 p.Research output: Contribution to journal › Journal article › peer-review
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Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes
Deacon, Carolyn F. & Holst, Jens Juul, Jan 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-40 8 p.Research output: Contribution to journal › Journal article › peer-review
ID: 9220
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339
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Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
Research output: Contribution to journal › Journal article › peer-review
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244
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Acute effects of dietary carbohydrate restriction on glycemia, lipemia and appetite regulating hormones in normal-weight to obese subjects
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237
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › peer-review
Published